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Role of Microorganisms and Their Metabolites in Agriculture, Food and the Environment: 3rd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 20 June 2026 | Viewed by 2558

Special Issue Editor


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Guest Editor
Department of Microbiology, Prof. Wacław Dąbrowski Institute of Agricultural and Food Biotechnology, 02-532 Warsaw, Poland
Interests: bacteriophages in food industry; non-thermal food processing; food microbiology; food safety; Alicyclobacillus spp. in beverage industry
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Special Issue Information

Dear Colleagues,

Even though people have been using microorganisms for thousands of years, they still surprise us with their possibilities.

The production of fermented foods is one of the oldest food processing technologies and has been known since ancient times. Nowadays, microorganisms are used in the production of foods not only as a strategy for food preservation but also for improving specific characteristics, such as flavor, aroma, texture and digestibility.

The antagonistic activity of microorganisms is widely used, both in biological plant protection to reduce environmental degradation due to the widespread use of fungicides and against food-borne pathogens to prevent disease.

In turn, the ability of microorganisms to adsorb, accumulate and degrade common and emerging pollutants has attracted the use of biological resources in treating contaminated food, feed and the environment.

This Special Issue will attempt to shed light on the molecular aspects and enhance the current research in the field of new high-throughput technologies, such as genomics, metagenomics, transcriptomics, metatranscriptomics and metabolomics, allowing a more thorough description of the microbial constituents of the different environments.

As volume 2 of the Special Issue “Role of Microorganisms and Their Metabolites in Agriculture, Food and the Environment: 2nd Edition” was successful, we reopen this issue again in the International Journal of Molecular Sciences (https://www.mdpi.com/journal/ijms, ISSN 1422-0067, IF 4.9, JCR Category Q1). This third Special Issue, “Role of Microorganisms and Their Metabolites in Agriculture, Food and the Environment: 3rd Edition”, welcomes original manuscripts and review articles addressing this hot topic.

Prof. Dr. Barbara Sokolowska
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • fermentation
  • biopreservation
  • biocontrol
  • biodegradation
  • bioremediation
  • bioaugmentation
  • omic-technologies

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Research

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18 pages, 5004 KB  
Article
Effects of Wood Biomass Combustion Residues on the Structure, Diversity, and Trophic Functions of Soil Fungi
by Jadwiga Wyszkowska, Edyta Boros-Lajszner, Małgorzata Baćmaga and Jan Kucharski
Int. J. Mol. Sci. 2026, 27(6), 2795; https://doi.org/10.3390/ijms27062795 - 19 Mar 2026
Cited by 1 | Viewed by 576
Abstract
Substances derived from the combustion of Carpinus betulus and Salix viminalis wood may have the potential to selectively modulate the structure and diversity of soil fungi. Therefore, the aim of this study was to evaluate their effects on the structure and diversity of [...] Read more.
Substances derived from the combustion of Carpinus betulus and Salix viminalis wood may have the potential to selectively modulate the structure and diversity of soil fungi. Therefore, the aim of this study was to evaluate their effects on the structure and diversity of the mycobiome, the physicochemical and thermodynamic properties of proteins, and the biomass of Zea mays. The pot experiment was conducted for 60 days on Eutric Cambisols soil developed from sandy loam (pHKCl = 4.37). Changes in the taxonomic profile of fungi were analyzed using the ITS region sequencing. Ascomycota dominated the control soil, while the addition of substances from the combustion of S. viminalis reduced their relative abundance, and C. betulus increased it. The growth of fungi of the genera Penicillium, Fusarium, Fusicolla, Chaetomium, and Mortierella was inhibited, whereas Iodophanus was stimulated by both additives. The abundance of Vishniacozyma spp. decreased after the addition of C. betulus and increased after the addition of S. viminalis. The most thermodynamically stable proteins were observed in the genera Fusarium and Penicillium, and the least stable in Mortierella and Vishniacozyma. Substances derived from tree biomass combustion significantly altered the diversity and evenness of fungal communities and exerted an inhibitory effect on both above-ground and root biomass of plants. These results suggest that the presence of these substances in the soil influences the structure and functional activity of fungi. Full article
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Review

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37 pages, 981 KB  
Review
Yeast as a Model for Human Disease
by Bartłomiej Zieniuk, Katarzyna Wierzchowska, Karina Jasińska, Joanna Kobus, Aleksandra Piotrowicz, Şuheda Uğur and Agata Fabiszewska
Int. J. Mol. Sci. 2026, 27(4), 1632; https://doi.org/10.3390/ijms27041632 - 7 Feb 2026
Cited by 1 | Viewed by 1636
Abstract
Yeasts, especially the conventional species Saccharomyces cerevisiae and Schizosaccharomyces pombe, as well as some unconventional species such as Pichia pastoris, Kluyveromyces marxianus and Yarrowia lipolytica, have become fundamental model organisms for understanding the molecular mechanisms underlying human diseases. Their eukaryotic [...] Read more.
Yeasts, especially the conventional species Saccharomyces cerevisiae and Schizosaccharomyces pombe, as well as some unconventional species such as Pichia pastoris, Kluyveromyces marxianus and Yarrowia lipolytica, have become fundamental model organisms for understanding the molecular mechanisms underlying human diseases. Their eukaryotic cell organization, genetic simplicity, and strong conservation of essential biological pathways make them indispensable in biomedical research. This review provides a comprehensive overview of the role of different yeast species in modeling human disorders, highlighting historical milestones and groundbreaking discoveries that have shaped current knowledge. The article discusses the applications of yeast models in studying neurodegenerative diseases such as Alzheimer’s and Huntington’s, as well as metabolic diseases, infectious diseases and mitochondrial disorders, and their growing importance in cancer research and drug discovery. Special attention is given to humanized yeast models, which enable the expression and functional analysis of human genes and the heterologous synthesis of human proteins within yeast cells. Finally, the paper addresses the limitations and challenges of yeast as a model system while outlining future directions and emphasizing the organism’s continued relevance in personalized medicine and functional genomics. Full article
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