Adipose Stem Cells 2019
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 January 2020) | Viewed by 76477
Special Issue Editors
Interests: pancreatic islet transplantation; islet regeneration; stem cell biology
Special Issues, Collections and Topics in MDPI journals
Interests: stem cell; tissue regeneration; biomaterials; epigenetics; aging; extracellular matrix; inflammation; 3D printing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of our 2018 Special Issue, “Adipose Stem Cells”.
Adipose tissue is a complex organ and in this last years it has received great attention thanks to its high stem cell content: adipose stem cells (ASC).
By definition, a stem cell is characterized by its ability to undergo self-renewal and differentiation, and form terminally differentiated cells. Ideally, a stem cell for regenerative medicinal applications should meet the following set of criteria: (i) it should be found in abundant quantities (millions to billions of cells); (ii) it can be collected and harvested by a minimally invasive procedure; (iii) it can be differentiated along multiple cell lineage pathways in a reproducible manner; (iv) it can be safely and effectively transplanted to either an autologous or allogeneic host. Adipose tissue serves as an abundant, accessible and rich source of adult stem cells with multipotent properties suitable for tissue engineering and regenerative medical applications.
The plasticity of ASC most often refers to the inherent ability retained within stem cells to cross lineage barriers and adopt the phenotypic, biochemical and functional properties of cells unique to other tissues.
There has been increased interest in adipose-derived stem cells (ASCs) for tissue engineering, regenerative medicine, biomaterial development and application, and with this in mind, the aim of the present Special Issue is the:
1) Characterization of the physiology of ASC;
2) Characterisation of the secretome activity of ASC;
3) Definition of transcriptional and non-transcriptional events related to their commitment; and
4) Application of ASC as a tool to test novel biomaterials for regenerative medicine
Prof. Dr. Hirofumi Noguchi
Prof. Dr. Barbara Zavan
Guest Editors
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Keywords
- Adult stem cells
- Mesenchymal stem cell
- Biomaterial
- Tissue regeneration
- Tissue engineering
- Regenerative medicine
- Implant surfaces
- Bone regeneration
- Osseointegration
- Wound healing
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