Innovative Applications of Metabolomics in Food Science

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Foodomics".

Deadline for manuscript submissions: 28 September 2025 | Viewed by 542

Special Issue Editors


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Guest Editor
Faculty of Chemistry, University of Belgrade, Studentski trg 12–16, 11000 Belgrade, Serbia
Interests: metabolomics; NMR and FTIR spectroscopy; food analysis; photochemistry; mass spectrometry; antimicrobial; materials

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Guest Editor
Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia
Interests: metabolomics; NMR spectroscopy; food analysis; photochemistry; mass spectrometry; structural elucidation; chromatography
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Special Issue Information

Dear Colleagues,

Almost eight billion people live on Earth, and that number is constantly increasing, leading to an increasing food demand. In recent years, there has been a growing need in the food industry, and among consumers, for instruments that can ensure the quality and origin of meals. This includes confirming the composition of the food and detecting any instances of fraud or misrepresentation. Multivariate data analysis is a crucial technique for examining extensive and intricate datasets, and it is widely used in several scientific fields, including genomics, transcriptomics, proteomics, metabolomics, and lipidomics. Metabolomic studies provide valuable insights into enhancing nutritional and functional characteristics, preventing foodborne illnesses, and comprehending the impacts of processing and storage. Furthermore, the progress in computer science and information technology has led to continuous advancements in the metabolomic technologies used in this sector.

This Special Issue will focus on the latest breakthroughs in metabolomic technologies that have been developed for assessing agricultural goods and diets. The subjects that will be discussed include the use of metabolomic technology to assess and analyze agricultural goods and foods, as well as methodological progress in metabolomic analysis employing agricultural and food-related big data.

Dr. Boban Anđelković
Prof. Dr. Dejan Gođevac
Guest Editors

Manuscript Submission Information

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Keywords

  • multivariate data analysis
  • metabolomics
  • food quality control
  • nuclear magnetic resonance spectroscopy
  • FTIR spectroscopy
  • mass spectrometry
  • foodomics

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Published Papers (1 paper)

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Research

26 pages, 8244 KB  
Article
Exploring the Effects of Nitrogen and Potassium on the Aromatic Characteristics of Ginseng Roots Using Non-Targeted Metabolomics Based on GC-MS and Multivariate Analysis
by Weiyu Cao, Hai Sun, Cai Shao, Hongjie Long, Yanmei Cui, Changwei Sun and Yayu Zhang
Foods 2025, 14(17), 2981; https://doi.org/10.3390/foods14172981 - 26 Aug 2025
Abstract
This study investigated individual/combined nitrogen (N) and potassium (K) deficiencies on ginseng root aroma using GC–MS metabolomics. Four treatments (normal supply, N deficiency (LN), K deficiency (LK), and dual deficiency (LNLK)) were analyzed. Deficiencies impaired growth, mineral accumulation, and induced oxidative stress, suppressing [...] Read more.
This study investigated individual/combined nitrogen (N) and potassium (K) deficiencies on ginseng root aroma using GC–MS metabolomics. Four treatments (normal supply, N deficiency (LN), K deficiency (LK), and dual deficiency (LNLK)) were analyzed. Deficiencies impaired growth, mineral accumulation, and induced oxidative stress, suppressing ginsenoside biosynthesis. From 1768 detected VOCs, 304 compounds (rOAV ≥ 1) significantly contributed to aroma. LN inhibited terpenoids (e.g., isoborneol) but upregulated sulfur compounds (e.g., di-2-propenyl tetrasulfide), intensifying pungency. LK enhanced sweet/woody notes (e.g., 2′-acetonaphthone) via flavonoid biosynthesis and toluene degradation. LNLK reduced esters (e.g., benzyl acetate) and terpenes, attenuating floral–balsamic nuances by coordinating aromatic degradation, glutathione metabolism, and ABC transporters. N–K nutrition dynamically shapes ginseng aroma by differentially regulating phenylpropanoid, terpenoid, and sulfur pathways, providing a foundation for precision fertilization and quality improvement. Full article
(This article belongs to the Special Issue Innovative Applications of Metabolomics in Food Science)
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