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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnosis and Management of Multisystem Wilson’s Disease

edited by

Tomasz Litwin

and

Agnieszka Antos

submission deadline 30 Apr 2026 | 1 articles | Viewed by 489 | Submission Open

Keywords: Wilson’ s disease; brain magnetic resonance imaging; biomarkers; copper metabolism; Wilson’ s disease mimicking disorders; zinc; chelators; liver transplantation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Diagnosis and Management of Breast Cancer

edited by Wing Lok Wendy Chan

submission deadline 30 Apr 2026 | 1 articles | Viewed by 464 | Submission Open

Keywords: breast cancer; diagnosis; treatment; personalized medicine; imaging techniques; immunotherapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Cardiothoracic and Abdominal Imaging: From CT Innovations to AI Diagnostics

edited by

Tommaso D'Angelo

submission deadline 30 Apr 2026 | 1 articles | Viewed by 426 | Submission Open

Keywords: cardiothoracic imaging; abdominal imaging; CT technologies; artificial intelligence (AI) in diagnosis; AI-based imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Microbiome-Based Diagnostics for Oncological Diseases: Innovations and Clinical Applications

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 30 Apr 2026 | Viewed by 314 | Submission Open

Keywords: microbiome-based diagnostics; disease biomarkers; gut microbiota; cancer microbiome; metagenomics; multi-omics in diagnostics; machine learning in microbiome analysis; dysbiosis and disease; precision medicine; microbiome– host interactions

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Molecular Mechanisms in Ophthalmology

edited by Deepshikha Tewari

submission deadline 30 Apr 2026 | Viewed by 295 | Submission Open

Keywords: ophthalmology; molecular mechanisms; cellular processes; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Traumatology: The Essential Role of Imaging in Diagnosis and Management

edited by

Meng-Yu Wu

and

Jui-Yuan Chung

submission deadline 30 Apr 2026 | Viewed by 257 | Submission Open

Keywords: traumatology; injury; mortality; functional outcomes; prehospital care; triage

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Biomedical Diagnostics and Analysis 2025

edited by

Prabal Datta Barua

Turker Tuncer

and

Sengul Dogan

submission deadline 30 Apr 2026 | 1 articles | Viewed by 232 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; medical signal and image processing; internet of medical things (IoMT); bioinformatics; explainable artificial intelligence; machine learning; uncertainty

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Non-Invasive Diagnostic Technologies for Heart Diseases

edited by Dentamaro Ilaria

submission deadline 30 Apr 2026 | 1 articles | Viewed by 228 | Submission Open

Keywords: transthoracic echocardiography; cardiac magnetic resonance; multimodality cardiovascular imaging; cardiac CT; transesophageal echocardiography; cardiovascular disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Diagnosis of Hypertension

edited by Vasileios Kotsis

submission deadline 30 Apr 2026 | Viewed by 192 | Submission Open

Keywords: hypertension; diagnosis; biomarkers; digital health; early detection

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 30 Apr 2026 | Viewed by 165 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Epidemiological Diagnostics: Advances and Applications

edited by

Jinhui Tian

submission deadline 30 Apr 2026 | Viewed by 145 | Submission Open

Keywords: artificial intelligence in diagnostic epidemiology; machine learning for diagnostic screening; predictive diagnostic modeling; automated diagnostic evidence synthesis; AI-designed peptides for diagnostics; antimicrobial peptide diagnostics; AI peptide engineering for pathogen detection; AI-driven population health diagnostics; diagnostic health informatics; digital diagnostic epidemiology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Biomarkers in Forensic Diagnosis

edited by Matteo Antonio Sacco and

Isabella Aquila

submission deadline 30 Apr 2026 | Viewed by 131 | Submission Open

Keywords: forensic biomarkers; postmortem interval estimation; forensic toxicology; molecular autopsy; sudden death investigation; forensic pathology; genetic markers; thanatology; forensic anthropology; cause of death determination

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Liquid Biopsy for Early Detection and Monitoring of Cancer

edited by Nicola Normanno,

Paola Ulivi

and

Tania Rossi

submission deadline 30 Apr 2026 | Viewed by 125 | Submission Open

Keywords: ctDNA; circulating tumor cells; microRNAs; exosomes; methylation; fragmentomics; early detection; minimal residual disease; artificial intelligence

Advances in the Diagnosis and Management of Chronic Disease

edited by

Lin Zhang

submission deadline 30 Apr 2026 | Viewed by 114 | Submission Open

Keywords: biomarkers; digital health technologies; artificial intelligence in diagnostics; non-invasive imaging; genomic screening; point-of-care testing; risk stratification models; multi-omics integration

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Low-Back Pain

edited by

Raffaele Natella

Federico Bruno

and Daniele Giuseppe Romano

submission deadline 30 Apr 2026 | Viewed by 114 | Submission Open

Keywords: low back pain; magnetic resonance imaging; radiculopathy; imaging biomarkers; patient selection; interventional radiology; epidural injections; radiofrequency ablation; intradiscal therapy; vertebral augmentation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathogenesis, Diagnosis, and Management of Rheumatic Disease: Progress and Challenges

edited by Miguel Ángel González-Gay

submission deadline 30 Apr 2026 | Viewed by 112 | Submission Open

Keywords: rheumatic disease; systemic vasculitis; rheumatoid arthritis; metabolic syndrome; atherosclerosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Management of Liver Tumors

edited by

Marija Radmilović-Radjenović

submission deadline 30 Apr 2026 | Viewed by 88 | Submission Open

Keywords: liver tumors; hepatocellular carcinoma; immunotherapy; imaging; oncology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Imaging Techniques in Reconstructive Microsurgery

edited by Marios N. Papadakis

submission deadline 30 Apr 2026 | Viewed by 87 | Submission Open

Keywords: reconstructive microsurgery; intraoperative imaging; indocyanine green angiography; high-resolution ultrasound; 3D imaging; magnetic resonance imaging (MRI); perfusion monitoring; imaging-guided surgery; dynamic thermography; surgical planning tools

(This special issue belongs to the Section Medical Imaging and Theranostics)

Operational Neurosurgery: Clinical Features, Diagnosis and Prognosis

edited by Xiaoyu Yang and Mark Wilson

submission deadline 30 Apr 2026 | Viewed by 86 | Submission Open

Keywords: cranial; spinel; peripheral nerve; pediatric; pre-operative evaluation; risk stratification; prognostic models; patient-reported outcomes; peri-operative pathways; equity; AI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrated Point-of-Care Testing (POCT) Systems: Recent Progress and Applications

edited by Kim Wolff

submission deadline 30 Apr 2026 | Viewed by 82 | Submission Open

Keywords: point-of-care testing (POCT); integrated diagnostic systems; nano-diagnostics; artificial intelligence (AI); clinical decision support; multi-biomarker panels; electronic health records (EHRs) connectivity; infectious disease diagnostics; decentralized healthcare

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 30 Apr 2026 | Viewed by 73 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Infectious Diseases in Obstetrics and Gynecology: Diagnosis and Management

edited by

Edward Araujo Júnior

submission deadline 30 Apr 2026 | Viewed by 70 | Submission Open

Keywords: infectious diseases; obstetrics; gynecology; diagnosis; management; sexually transmitted diseases; congenital malformations; chronic pelvic pain; infertility

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Precision Diagnosis and Treatment of Chorioretinal Diseases: From Biomarkers to Imaging

edited by

Jay Kumar Chhablani

submission deadline 30 Apr 2026 | Viewed by 64 | Submission Open

Keywords: ocular imaging; biomarkers; retinal imaging; retinal diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Fetal, Placental, and Pediatric Dermatopathology: From Development to Disease

edited by

Ovidiu Simion Cotoi

and

Diana-Maria Chiorean

submission deadline 30 Apr 2026 | Viewed by 62 | Submission Open

Keywords: fetal pathology; placental pathology; pediatric pathology; pediatric dermatopathology; neonatal dermatology; inflammation; vascular lesions; congenital disorders; molecular pathology; developmental disease; perinatal outcomes

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Genomics in Cardiac Diagnostics: Bridging Novel Insights to Clinical Practice

edited by

Yiqing Yang

submission deadline 30 Apr 2026 | Viewed by 60 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; cardiac arrhythmia; idiopathic cardiomyopathy; coronary heart disease; arterial hypertension; stroke; genetics; genomics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Precision Medicine for Prostate Cancer: From Molecular Imaging to Targeted Diagnosis and Therapy

edited by

Kalevi Kairemo

and

Finn Edler von Eyben

submission deadline 30 Apr 2026 | Viewed by 57 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; PSMA; prostate cancer

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Viral Respiratory Infections, 2nd Edition

edited by

Federica Novazzi

submission deadline 30 Apr 2026 | Viewed by 51 | Submission Open

Keywords: respiratory tract infections; lower respiratory tract infections (LRTIs); upper respiratory tract infections (URTIs); whole-genome sequencing (WGS); immunological techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Innovative Solutions to Cardiovascular Dilemmas: From Diagnosis to Therapy, Second Edition

edited by

Thach N. Nguyen

and C Michael Gibson

submission deadline 30 Apr 2026 | 1 articles | Viewed by 47 | Submission Open

Keywords: coronary artery disease; acute coronary syndrome; heart failure; hemodynamics in heart failure; coronary flow dynamic; dilated cardiomyopathy; valvular disease; atrial fibrillation; sudden cardiac death; syncope; individualized treatment; clinical decision-making; computational fluid dynamic; big data analysis; artificial intelligence; machine learning

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging in Heart Failure: Advances, Applications, and Future Directions

edited by

Attila Frigy

submission deadline 30 Apr 2026 | Viewed by 43 | Submission Open

Keywords: heart failure; echocardiography; cardiovascular magnetic resonance (CMR); computed tomography (CT); nuclear imaging (PET/SPECT); prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Robotics in Disease Diagnosis and Management

edited by Michele Tedeschi

submission deadline 30 Apr 2026 | Viewed by 42 | Submission Open

Keywords: robotic surgery; disease diagnosis; disease management; outcomes; robotic systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Cancer Pathology and Diagnosis, Second Edition

edited by

Lorenzo Memeo

submission deadline 30 Apr 2026 | Viewed by 38 | Submission Open

Keywords: histopathology; histological classification; cancer biomarkers; digital pathology; AI applications; next-generation sequencing; real-time PCR

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Prostate Cancer: Innovations in Diagnosis and Risk Stratification

edited by Biren Saraiya

submission deadline 30 Apr 2026 | Viewed by 36 | Submission Open

Keywords: prostate cancer; diagnostics; therapeutics; molecular targets; Prostate Specific Membrane Antigen (PSMA); risk stratification; radioligand therapy; multimodal therapy; clinical guidelines

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ovarian Cancer in 2025–2026: A Comprehensive Look at Characteristics, Screening, Diagnosis and Treatment

edited by

Edward J. Pavlik

submission deadline 1 May 2026 | 2 articles | Viewed by 5171 | Submission Open

Keywords: ovarian cancer; risk; treatment; detection; screening; trial design; treatment; collateral effects; endpoints; costs; efficacy; AI; sojourn time models; vaccines; PARP inhibitors; liquid biopsies; post treatment hematologic malignancies; HIPEC; STIC/STIL

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Thyroid Disorders: New Clinical Diagnosis and Management

edited by

Ioannis P. Iakovou

Rodis D. Paparodis

and

Nicholaos G. Angelopoulos

submission deadline 15 May 2026 | Viewed by 99 | Submission Open

Keywords: thyroid disorders; clinical diagnosis; ultrasound; elastography; thyroid cancer; thyroiditis; hyperthyroidism; hypothyroidism; advanced imaging

Advances in Nephrology

edited by

Marijn M. Speeckaert

submission deadline 30 May 2026 | 9 articles | Viewed by 36284 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnostic and Therapeutic Strategies for Infectious Diseases

edited by

Margherita Sambo

submission deadline 31 May 2026 | 6 articles | Viewed by 11912 | Submission Open

Keywords: infectious diseases; diagnostic advancements; therapeutic strategies; antimicrobial resistance; molecular diagnostics; clinical management; emerging pathogens; precision medicine

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Management of Ophthalmic Disorders

edited by Assaf Kratz

submission deadline 31 May 2026 | 7 articles | Viewed by 7456 | Submission Open

Keywords: ocular diseases; early diagnosis; advanced imaging; glaucoma; age-related macular degeneration; diabetic retinopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endoscopic Diagnostics for Pancreatobiliary Disorders 2025

edited by

Masataka Kikuyama

submission deadline 31 May 2026 | 3 articles | Viewed by 4853 | Submission Open

Keywords: endoscopic ultrasonography; endoscopic retrograde cholangiopancreatography; EUS– FNA; SPACE; pancreatic cancer; bile duct caner; gallbladder cancer

(This special issue belongs to the Section Biomedical Optics)

DNA Sequencing of Infectious Diseases

edited by

Edward R. B. Moore

and

Daniel Jaén Luchoro

submission deadline 31 May 2026 | 4 articles | Viewed by 4661 | Submission Open

Keywords: DNA sequencing; infectious disease; diagnostics; screening; whole-genome sequencing; targeted amplicon sequencing

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnostic Methods in Forensic Pathology, Third Edition

edited by

Gennaro Baldino

and

Elvira Ventura Spagnolo

submission deadline 31 May 2026 | 3 articles | Viewed by 4104 | Submission Open

Keywords: multidisciplinary approach; forensic pathology; sudden/unexpected death; sepsis and health infections; suicide; gender violence; post-mortem immunohistochemistry; post-mortem CT; virtopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Emergency Medicine: Diagnostic Insights

edited by Ancor Sanz-Garcia and Raúl López-Izquierdo

submission deadline 31 May 2026 | 3 articles | Viewed by 3976 | Submission Open

Keywords: diagnostic tools; point-of-care testing; prehospital; emergency medicine; rapid and accurate diagnosis; imaging modalities; biomarkers; AI-driven algorithms

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Radiology in the Third Millennium: New Patient-Centered Diagnostic Approaches

edited by

and Fabrizio Urraro

submission deadline 31 May 2026 | 2 articles | Viewed by 3830 | Submission Open

Keywords: radiology; diagnostics; patient-specific imaging; AI; deep learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Oral and Maxillofacial Imaging

edited by

Jòzsef Piffkó

and

Agnes Janovszky

submission deadline 31 May 2026 | 2 articles | Viewed by 3560 | Submission Open

Keywords: technological advancements; diagnostic imaging; treatment planning; clinical applications; oral and maxillofacial surgery; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management

edited by Ombretta Martinelli and

Antonio Marzano

submission deadline 31 May 2026 | 4 articles | Viewed by 3497 | Submission Open

Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence Approaches for Medical Diagnostics in the USA

edited by

Jinzhong Yang

and Yao Zhao

submission deadline 31 May 2026 | 3 articles | Viewed by 3417 | Submission Open

Keywords: artificial intelligence; medical image segmentation; image registration; image quality enhancement; image artifact reduction; radiomics; image reconstruction; deep learning in diagnostics; AI-driven medical Imaging; diagnostic accuracy; diagnostic imaging innovations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases

edited by

Corina Maria Vasile

and Xavier Iriart

submission deadline 31 May 2026 | 3 articles | Viewed by 3206 | Submission Open

Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition

edited by Costantino Ricci

submission deadline 31 May 2026 | 3 articles | Viewed by 3019 | Submission Open

Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Histopathology in Cancer Diagnosis and Prognosis—2nd Edition

edited by

Christina Magkou

submission deadline 31 May 2026 | 1 articles | Viewed by 2772 | Submission Open

Keywords: cancer; precision medicine; histopathology; diagnosis; prognostic/predictive markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis of Digestive Diseases

edited by Noriaki Manabe

submission deadline 31 May 2026 | 2 articles | Viewed by 2564 | Submission Open

Keywords: diagnosis of gastrointestinal disease; functional gastrointestinal disorders; organic diseases; personalized medicine; physiological function evaluation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus

edited by

Elisabeth Kapaki

and

Efstratios-Stylianos Pyrgelis

submission deadline 31 May 2026 | 1 articles | Viewed by 2495 | Submission Open

Keywords: idiopathic normal pressure hydrocephalus (iNPH); neurological disorder; ventricular enlargement; cerebrospinal fluid (CSF) dynamics; cognitive impairment; gait disturbance

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 451-500 on page 10 of 15.

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