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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biomarkers and Biodiagnostics in Neurodegenerative Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 31 Jan 2027 | 1 articles | Viewed by 525 | Submission Open

Keywords: neurodegenerative diseases; biomarkers; biodiagnostics; protein misfolding

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

AI and Explainable Intelligence for Medical Diagnosis: Emerging Trends and Future Directions

edited by

Olamilekan Shobayo

submission deadline 31 Jan 2027 | 1 articles | Viewed by 520 | Submission Open

Keywords: artificial intelligence; deep learning; vision transformers (ViTs); generative AI (GANs, VAEs, diffusion models); multimodal learning; radiology AI; image segmentation and classification; explainable AI (XAI); clinical decision support; medical image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Tumor Cytopathology: Diagnostic Innovations and Applications

edited by Joshua Jing Xi Li and Swati Satturwar

submission deadline 31 Jan 2027 | Viewed by 414 | Submission Open

Keywords: cytopathology; digital pathology; tumor; molecular pathology; diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Breakthroughs in Advanced Medical X-Ray and CT Imaging: From Technology to Clinical Application

edited by Joyoni Dey

submission deadline 31 Jan 2027 | Viewed by 399 | Submission Open

Keywords: advanced X-ray CT imaging; X-ray CT interferometry; phase-contrast X-ray; photon-counting detectors

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging in Heart Failure: Advances, Applications, and Future Directions

edited by

Attila Frigy

submission deadline 31 Jan 2027 | Viewed by 360 | Submission Open

Keywords: heart failure; echocardiography; cardiovascular magnetic resonance (CMR); computed tomography (CT); nuclear imaging (PET/SPECT); prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Meta-Analytical Approaches and Novel Diagnostic Technologies in Cardiovascular Medicine

edited by

Raheel Ahmed

submission deadline 31 Jan 2027 | Viewed by 355 | Submission Open

Keywords: meta-analysis; evidence synthesis; cardiovascular diagnosis; clinical evidence; evidence-based medicine; diagnostic accuracy; systematic review

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cardiovascular Diseases: Diagnosis and Management, Second Edition

edited by Hezzy Shmueli

submission deadline 31 Jan 2027 | Viewed by 344 | Submission Open

Keywords: real-time imaging; cardiovascular disease; cardiovascular imaging; echocardiography; cardiac CT; cardiac MRI; cardiac nuclear scan; acute cardiac care; artificial intelligence; cardiomyopathy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Updated in Endocrine Pathology: From New Diagnosis Tools to Cross-Disciplinary Teams

edited by

Mara Carsote

submission deadline 31 Jan 2027 | Viewed by 342 | Submission Open

Keywords: adrenal; adrenalectomy; thyroid; thyroid cancer; thyroidectomy; pituitary gland; prolactin; hormone; endocrine; dynamic testing; biomarker; computer tomography; magnetic resonance imaging; scintigraphy; DXA; osteoporosis; bone; muscle

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Machine Learning for Computer-Aided Diagnosis in Biomedical Imaging—3rd Edition

edited by

Farhan Akram

submission deadline 31 Jan 2027 | Viewed by 275 | Submission Open

Keywords: cancer diagnosis; medical images; electronic health records; machine learning; deep learning; artificial intelligence; explainable AI models; multi-modal analysis; federated learning; CAD systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Driven Diagnosis and Management in Otolaryngology

edited by

Zhiyu Wan

, Hui Yang and

Yike Li

submission deadline 22 Feb 2027 | Viewed by 304 | Submission Open

Keywords: artificial intelligence; otolaryngology; precision medicine; human voice; multimodal data; digital biomarkers; medical imaging; physiologic signal analysis; clinical decision support; translational medicine; responsible AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Adverse Drug Reactions in Precision Medicine and Big Data

edited by

Elena Ramírez

submission deadline 28 Feb 2027 | 2 articles | Viewed by 19802 | Submission Open

Keywords: adverse drug reactions; pharmacovigilance; drug safety; risk factors; causality assessment; big data; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology, Second Edition

edited by

Ke-Vin Chang

submission deadline 28 Feb 2027 | 9 articles | Viewed by 19745 | Submission Open

Keywords: diagnosis; ultrasound; pain; muscle; tendon; nerve; rehabiltation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases

edited by

Corina Maria Vasile

and Xavier Iriart

submission deadline 28 Feb 2027 | 5 articles | Viewed by 8849 | Submission Open

Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Application of Ultrasound Imaging in Clinical Diagnosis

edited by

Jinbum Kang

submission deadline 28 Feb 2027 | 7 articles | Viewed by 8485 | Submission Open

Keywords: diagnostic ultrasound imaging and systems; doppler ultrasound techniques and applications; elastography for tissue characterization; contrast-enhanced ultrasound (CEUS); artificial intelligence in diagnostic ultrasound; point-of-care ultrasound (POCUS); ultrasound-guided interventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Role of Endoscopic Ultrasound in Clinical Medicine

edited by

Germana De Nucci

submission deadline 28 Feb 2027 | 3 articles | Viewed by 7996 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic imaging; fine needle aspiration (FNA); contrast-enhanced EUS; elastography techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Anatomy and Diagnosis of Peripheral Nervous System—2nd Edition

edited by

Alexandra Diana Vrapciu

submission deadline 28 Feb 2027 | 3 articles | Viewed by 6964 | Submission Open

Keywords: anatomy; peripheral nervous system; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Alzheimer’s Disease Diagnosis—2nd Edition

edited by

Mohammad Shahadat Hossain

submission deadline 28 Feb 2027 | 6 articles | Viewed by 6347 | Submission Open

Keywords: Alzheimer’s disease; artificial intelligence; machine learning; explainable AI; expert systems; computer vision; deep learning; diagnosis; cognition; brain informatics; neurodegenerative disorder

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Multimodal Assessment of Musculoskeletal Conditions

edited by

Stanley K. H. Lam

and Bradley Dean Fullerton

submission deadline 28 Feb 2027 | 2 articles | Viewed by 5612 | Submission Open

Keywords: musculoskeletal disorders; multimodal assessment; biotensegrity; diagnostic ultrasound; imaging; biomechanics; rehabilitation monitoring; patient-reported outcomes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endoscopy in Gynecology and Gynecologic Oncology

edited by

Rudolf Lampé

submission deadline 28 Feb 2027 | 1 articles | Viewed by 5103 | Submission Open

Keywords: gynecology; endoscopy; operative gynecology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Precise Diagnosis, Classification, and Monitoring of Pulmonary Diseases

edited by

Barbara Ruaro

Paola Confalonieri

and

Francesco Salton

submission deadline 28 Feb 2027 | 4 articles | Viewed by 4411 | Submission Open

Keywords: lung diseases; pulmonary diseases; imaging techniques; causal biological pathways; clinical biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Fetal Doppler Assessment: From Basic Research to Clinical Practice

edited by Luís Guedes-Martins

submission deadline 28 Feb 2027 | 1 articles | Viewed by 4257 | Submission Open

Keywords: fetal Doppler; fetal growth restriction; preeclampsia; fetal-placental hemodynamics; fetal death; placental abruption; placental circulation; fetal cerebral circulation; fetal hepatic circulation; fetal heart function

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emerging Technologies and Diagnostic Innovations in Optometry and Vision Science

edited by

Shuan-Yu Huang

submission deadline 28 Feb 2027 | 4 articles | Viewed by 4090 | Submission Open

Keywords: optometry; vision diagnostics; ocular imaging; binocular vision; accommodation–vergence; AI in eye care; visual training; digital theranostics; sports vision; VR/AR; smart medical devices

(This special issue belongs to the Section Biomedical Optics)

Diagnostic Imaging in Urologic Disorders

edited by Matteo Droghetti

submission deadline 28 Feb 2027 | 4 articles | Viewed by 3567 | Submission Open

Keywords: diagnostic imaging; urologic disorders; ultrasound; CT; MRI; PET; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Hearing and Audiology Science: Diagnosis and Management, 2nd Edition

edited by

Yu Sun

submission deadline 28 Feb 2027 | 3 articles | Viewed by 3382 | Submission Open

Keywords: hearing loss; genetic deafness; cochlear implants; hair cell regeneration; central auditory processing; vestibular disorders; tinnitus; intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 28 Feb 2027 | 3 articles | Viewed by 3025 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Expanding Horizons: Optical Coherence Tomography in Cross-Specialty Diagnostic Practice

edited by

Nicusor Iftimia

submission deadline 28 Feb 2027 | 3 articles | Viewed by 2502 | Submission Open

Keywords: optical coherence tomography; cross-specialty diagnosis; AI-assisted OCT; OCT angiography; multimodal imaging

(This special issue belongs to the Section Biomedical Optics)

Advances in Inflammation and Infection Imaging: 2nd Edition

edited by

Giorgio Treglia

submission deadline 28 Feb 2027 | 2 articles | Viewed by 2277 | Submission Open

Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Horizons in Multiple Myeloma Diagnosis and Therapy

edited by Ulrike Dapunt

submission deadline 28 Feb 2027 | Viewed by 2219 | Submission Open

Keywords: multiple myeloma diagnosis and therapy; imaging techniques; biomarkers; genetic and epigenomic profiling; supportive cancer care; exercise therapy; nutrition; pain management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Thyroid Nodule and Cancer Diagnostics

edited by

Kwangsoon Kim

submission deadline 28 Feb 2027 | 2 articles | Viewed by 2007 | Submission Open

Keywords: thyroid nodule; thyroid cancer; diagnostic imaging; molecular diagnostics; ultrasound elastography; Fine-Needle Aspiration (FNA); artificial intelligence; risk stratification; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging Methods in Obstetrics and Gynecology

edited by

Dan-Bogdan Navolan

Dana Stoian

, Laurenţiu Cornel Pirtea, Adrian Ratiu and Dan Dumitrascu-Biris

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1910 | Submission Open

Keywords: obstetric imaging; gynecologic imaging; prenatal ultrasound; fetal MRI; elastography; AI-assisted diagnosis; materno-fetal medicine; breast imaging; fetal lesions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pain Medicine: Diagnostic and Management Innovations

edited by Yuchen Lee, Dongwoo Nam and Cheng-Hao Tu

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1758 | Submission Open

Keywords: pain medicine; chronic pain; neuropathic pain; nociplastic pain; biomarkers; imaging; quantitative sensory testing; artificial intelligence; digital health; multimodal analgesia; neuromodulation; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Forensic Imaging

edited by

Oguzhan Ekizoglu

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1667 | Submission Open

Keywords: forensic imaging; postmortem imaging; artificial intelligence; 3D reconstruction; foren-sic radiology; forensic anthropology

(This special issue belongs to the Section Forensic Diagnostics)

Latest Innovations in Interventional Oncology

edited by

Pierleone Lucatelli

and

David C. Madoff

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1322 | Submission Open

Keywords: contrast-enhanced ultrasound (CEUS); hybrid PET-MRI oncology imaging; optical coherence tomography (OCT) diagnostics; AI-driven lesion segmentation; radiomics-based tumor profiling; liquid biopsy innovations; endovascular biomarker sampling; molecular imaging specificity; real-time tumor characterization; image-guided diagnostic paradigms

(This special issue belongs to the Section Medical Imaging and Theranostics)

Challenges in the Diagnosis and Treatment of Cardiac and Respiratory Infections

edited by

Alessandro Russo

and Francesca Serapide

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1241 | Submission Open

Keywords: cardiac infections; respiratory infections; diagnostic challenges; antimicrobial resistance; biomarkers; molecular diagnostics; targeted therapies; cardiopulmonary disease

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Diagnosis and Treatment of Hematological Diseases

edited by

Mirjana Mitrovic

and

Nikola Pantic

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1230 | Submission Open

Keywords: hematology; anemia; thrombocytopenia; bleeding; thrombosis; hemostasis; leukemia; lymphoma; myeloma; diagnosis; therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

From Variability to Reliability: Standardization, Interference, and the Future of Laboratory Medicine

edited by

Katarzyna Winsz-Szczotka

submission deadline 28 Feb 2027 | Viewed by 1178 | Submission Open

Keywords: laboratory medicine; standardization; diagnostic reliability; sample quality; automation; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis of Skin Disease: 2nd Edition

edited by

Gerardo Cazzato

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1135 | Submission Open

Keywords: dermatology; dermatopathology; skin diseases; neoplastic diseases; inflammatory dermatopathology; CTCL; melanoma; squamous cell carcinoma; basal cell carcinoma; infectious diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging of Long-COVID (Post-Acute Sequelae of COVID, PASC) and Post-Infectious Syndromes

edited by

Eric Guedj

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1025 | Submission Open

Keywords: long COVID; post-acute sequelae of COVID (PASC); COVID-19; SARS-CoV-2; post-infectious syndromes; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); medical imaging; nuclear medicine; PET; SPECT; MRI; CT; ultrasound; imaging biomarkers; metabolism; neuroinflammation; microvascular dysfunction; multisystem involvement; diagnosis; prognosis; rehabilitation; functional impairment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Modern Diabetes Diagnosis and Treatment Technology, Second Edition

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 28 Feb 2027 | Viewed by 994 | Submission Open

Keywords: diabetes; complications; diagnosis; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; technology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Placental Pathology

edited by

Vincenzo Arena

and Eleonora Nardi

submission deadline 28 Feb 2027 | 1 articles | Viewed by 948 | Submission Open

Keywords: placental pathology; placental development; gestational diseases; histopathological examination; pregnancy outcomes; forensic issues

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovative Biomarkers and Diagnostic Strategies in Immune-Mediated Diseases

edited by

Marcos López Hoyos

submission deadline 28 Feb 2027 | 1 articles | Viewed by 936 | Submission Open

Keywords: immune-mediated diseases; innovative biomarkers; diagnostic strategies; classification criteria; laboratory techniques

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Endoscopy—A New Era in Gastrointestinal Diagnostics, 2nd Edition

edited by

Ervin Toth

and

Anastasios Koulaouzidis

submission deadline 28 Feb 2027 | Viewed by 888 | Submission Open

Keywords: AI-supported detection, classification, and workflow in endoscopy; innovations in capsule and device-assisted endoscopy; image enhancement technologies and real-time analytics; therapeutic endoscopic advances and new instrumentation; integration of digital tools and automation into clinical practice; perspectives on training, quality, and standardization; ethical and regulatory considerations in emerging technologies

(This special issue belongs to the Section Biomedical Optics)

Recent Advances in Clinical Biochemical Testing: 2nd Edition

edited by

Tar-Choon Aw

submission deadline 28 Feb 2027 | Viewed by 864 | Submission Open

Keywords: clinical chemistry; diagnostic testing; biomarkers; point-of-care testing; mass spectrometry; immunoassays; microfluidics

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Molecular Diagnostics for Solid Tumors

edited by

Thais Maloberti

submission deadline 28 Feb 2027 | Viewed by 825 | Submission Open

Keywords: rare tumors; solid tumors; NGS; artificial intelligence; molecular profiling; precision oncology; epigenetic biomarkers; liquid biopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Surgical Diagnosis and Management of Inflammatory Diseases in Hepatobiliary and Pancreatic Systems

edited by

Roberto Cotellese

and

Federico Selvaggi

submission deadline 28 Feb 2027 | 1 articles | Viewed by 825 | Submission Open

Keywords: surgical diagnosis; diagnostic biomarkers; intraoperative imaging; pathology; risk stratification; disease differentiation; prognostic assessment; hepatobiliary inflammation; pancreatic inflammation; minimally invasive biopsy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Quantum Machine Learning in Medical Image and Signal Processing

edited by Yolanda Vives-Gilabert

submission deadline 28 Feb 2027 | Viewed by 824 | Submission Open

Keywords: quantum machine learning; medical imaging; medical signal processing; variational quantum circuits

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advancing Precision Cardiovascular Imaging: From Metabolic Disorders to Cardiomyopathies and Rare Cardiac Diseases

edited by

Chung Lieh Hung

submission deadline 28 Feb 2027 | 1 articles | Viewed by 800 | Submission Open

Keywords: cardiomyopathy; rare disease; echocardiography; nuclear imaging; cardiac MRI; computed tomograph

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Imaging and Artificial Intelligence in Emergency Body Radiology

edited by

Francesco Verde

and

Francesca Iacobellis

submission deadline 28 Feb 2027 | Viewed by 727 | Submission Open

Keywords: emergency radiology; advanced imaging; artificial intelligence; dual-energy CT; photon-counting CT; MRI acceleration; contrast-enhanced ultrasound; deep learning; radiomics; workflow optimisation; clinical validation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Quantitative Imaging of Respiratory Diseases: Techniques and Clinical Applications

edited by Chenwang Jin and

Yanrong Chen

submission deadline 28 Feb 2027 | Viewed by 725 | Submission Open

Keywords: quantitative imaging; HRCT; radiomics; machine learning; respiratory diseases; imaging biomarkers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Applications of Artificial Intelligence and Non-Invasive Electrocardiograms in Disease Diagnosis

edited by

Constantinos Bakogiannis

and Samuel L. Johnston

submission deadline 28 Feb 2027 | Viewed by 515 | Submission Open

Keywords: artificial intelligence (AI); non-invasive electrocardiogram (ECG); disease diagnosis; medical imaging analysis; machine learning; deep learning; cardiovascular diseases; pattern recognition; data analytics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Displaying special issue 351-400 on page 8 of 13.

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