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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in the Diagnosis and Management of Liver Disease and Liver Transplantation

edited by Ioana Gabriela Lupescu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4618 | Submission Open

Keywords: focal and diffuse liver pathology; liver transplantation; MPMRI; MDCT; advanced imaging techniques; specific liver contrast material; imaging biomarkers; interventional radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Next-Generation Diagnostic Strategies: Bridging Health Sciences and Laboratory Medicine

edited by

Syed M. Shahid

submission deadline 28 Feb 2026 | 1 articles | Viewed by 4606 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; prevision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Laboratory Medicine)

Clinical Diagnosis and Management in Anesthesia and Pain Medicine

edited by Jamal Hasoon

submission deadline 28 Feb 2026 | 4 articles | Viewed by 4580 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Perspectives and Gaps in the Diagnosis and Management of Rheumatic Diseases

edited by Vikas Majithia

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4512 | Submission Open

Keywords: rheumatology; rheumatic diseases; inflammatory connective tissue diseases; rheumatoid arthritis; systemic lupus erythematosus; vasculitis; spondyloarthritis; scleroderma; osteoarthritis; current perspective; diagnosis; treatment; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Imaging of the Future: From the Standardisation of Diagnostic Processes to Artificial Intelligence

edited by

Emanuele David

submission deadline 28 Feb 2026 | 1 articles | Viewed by 4228 | Submission Open

Keywords: artificial intellicence; technologies; ultrasound; MRI; CT; angiography; mammography

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances and Approaches in Managing Neurological Disorders: Multi-Omics and P4 Medicine

edited by

Shashanka Ashili

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4203 | Submission Open

Keywords: multi-omics; neurological disorders; P4 medicine; Appomics; neurodegenerative disorders; neurodevelopmental disorders; personalized medicine; bioinformatics; aging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Management in Pediatric Surgery

edited by Ioannis A. Valioulis

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4066 | Submission Open

Keywords: pediatric surgery; neonatal surgery; pediatric urology; pediatric oncology; laparoscopy in children; robotic surgery for children; organ transplantation; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Thyroid Cancer: Types, Symptoms, Diagnosis and Management

edited by

Mara Carsote

, Mihai-Lucian Ciobica and

Claudiu Nistor

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4000 | Submission Open

Keywords: thyroid neoplasia; thyroiditis; imaging; functional imaging; thyroidectomy; tumor markers; histological exam; molecular findings; pediatric population; pregnancy and thyroid conditions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3844 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Alzheimer's Disease Diagnosis Based on Deep Learning

edited by Anees Abrol

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3402 | Submission Open

Keywords: Alzheimer's disease (AD); deep learning; MRI; demographic information; disease probability map; convolutional neural network (CNN)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Insights for Skin Melanoma

edited by

Luca Roncati

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3191 | Submission Open

Keywords: skin melanoma; tissue biopsy; histopathological examination; immunohistochemistry; dermatoscopy; reflectance confocal microscopy; modern artificial intelligence; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovative Diagnostic Approaches in Retinal Diseases

edited by

Benedetto Falsini

and Andrea Cusumano

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2938 | Submission Open

Keywords: retinal diseases; electrophysiology; imaging; optical coherence tomography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis, Treatment, and Management of Hair Disorders

edited by Neil Jairath and

Vignesh Ramachandran

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2689 | Submission Open

Keywords: hair loss; alopecia; management; cicatricial; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging in Bone and Soft-Tissue Sarcomas: Practice, Education, and Innovation—2nd Edition

edited by

Paolo Spinnato

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2667 | Submission Open

Keywords: soft-tissue sarcomas; bone sarcomas; imaging; MRI; CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Endocrinology Pathology

edited by

Mara Carsote

Ana Valea

and

Claudiu Nistor

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2219 | Submission Open

Keywords: histological classification and reporting; cytological analysis; fine-needle aspiration; molecular markers; immunohistochemistry; hormone; dynamic hormonal testing; endocrine tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management in Cardiac Intensive Care Medicine

edited by

Elad Asher

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2200 | Submission Open

Keywords: cardiac intensive care; cardiogenic shock; acute heart failure; hemodynamic monitoring; mechanical circulatory support; post-cardiac arrest care; critical care cardiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Trends in Cardiovascular Imaging: 2nd Edition

edited by

Hans-Christoph Becker

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2106 | Submission Open

Keywords: cardiac CT; cardiac MRI; hybrid and multimodality imaging; artificial intelligence and machine learning; coronary artery disease; myocardial tissue characterization; congenital heart disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Skin Diseases

edited by

Montserrat Fernández-Guarino

submission deadline 28 Feb 2026 | 4 articles | Viewed by 2065 | Submission Open

Keywords: dermatology; skin disease; molecular diagnostics; laboratory test; assessment of therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Microwave Radiometry for R&D and Practical Applications in 2025

edited by

Igor Goryanin

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1856 | Submission Open

Keywords: microwave radiometry; core body temperature; breast cancer detection; artificial intelligence; COVID-19 pneumonia; vulnerable plaque; carotid; hypothermia; hyperthermia; ischemic stroke; traumatic brain injury; rheumatoid arthritis; diabetic foot; brown adipose tissue activity; vesicoureteral reflux

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Application of Neural Networks in Medical Diagnosis

edited by

Hamid Reza Marateb

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1834 | Submission Open

Keywords: neural networks in diagnostics; medical imaging analysis; deep learning in healthcare; predictive modeling for disease detection; clinical decision support systems; interpretability and explainability in AI; biomedical data processing; personalized medicine applications

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Biomarkers for Cardiovascular Disease

edited by

Manuela Ciocoiu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1822 | Submission Open

Keywords: cardiovascular risk factors; hypertension; dyslipidemia; overweight; obesity; diabetes mellitus; metabolic syndrome; atherosclerosis; physical inactivity; biomarkers; cardiovascular disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ultrasound Elastography in Musculoskeletal Disorders: From Bench to Bedside

edited by Yoshiki Yamakoshi

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1662 | Submission Open

Keywords: ultrasound elastography; shear wave elastography; musculoskeletal ultrasound; tissue elasticity; tendon and ligament imaging; myofascial pain syndrome; sports medicine; rehabilitation; diagnostic imaging; muscle stiffness

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Anatomy and Diagnosis of Peripheral Nervous System—2nd Edition

edited by

Alexandra Diana Vrapciu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1632 | Submission Open

Keywords: anatomy; peripheral nervous system; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Subjective Experiences of Decline and Dementia Risk: Cognitive, Functional, and Emotional Predictors of Cognitive Decline

edited by Katya Numbers

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1575 | Submission Open

Keywords: subjective cognitive decline (SCD); dementia risk; cognitive complaints; functional decline; emotional well-being; early diagnosis and intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Application of Radiomics in Clinical Diagnosis

edited by

Alfonso Reginelli

and

Vittorio Patanè

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1520 | Submission Open

Keywords: radiomics; clinical diagnosis; medical imaging; quantitative imaging biomarkers; artificial intelligence; machine learning; image analysis; precision medicine; computer-aided diagnosis; multimodal imaging; feature extraction; predictive modeling; diagnostic imaging; integrative diagnostics; imaging biomarkers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Maternal–Fetal Medicine

edited by Roxana Elena Bohiltea

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1396 | Submission Open

Keywords: maternal– fetal medicine; pregnancy; prenatal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Impacts and Value of Anatomy, 2nd Edition

edited by

Maria Piagkou

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1182 | Submission Open

Keywords: musculoskeletal anatomy; clinical anatomy; surgical anatomy; vascular; nervous system; anatomical variations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Prenatal Diagnosis: From Morphological Evaluation to Genetic Testing

edited by

Antonio Pizzuti

and

Gioia Mastromoro

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1086 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound (US); fetal magnetic resonance imaging (MRI); chromosomal microarray analysis; next-generation sequencing; exome sequencing; genome sequencing; non-invasive prenatal screening; non-invasive prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Cone Beam Computed Tomography for Maxillofacial Diseases, Third Edition

edited by

Yiu Yan Leung

submission deadline 28 Feb 2026 | 2 articles | Viewed by 815 | Submission Open

Keywords: cone-beam computed tomography; imaging; radiology; oral and maxillofacial surgery; dentistry; diagnosis; risk management; 3D printing; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances and Challenges in the Diagnosis and Treatment of Rheumatic Diseases

edited by

Anastas Batalov

Mariela Geneva-Popova

and Zgurov Batalov

submission deadline 28 Feb 2026 | 1 articles | Viewed by 613 | Submission Open

Keywords: rheumatology ; rheumatic diseases ; musculoskeletal ultrasound ; clinical diagnostics ; biomarkers ; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Pathology for Forensic Diagnosis

edited by

Cristina Mondello

and Vincenzo Cianci

submission deadline 28 Feb 2026 | 1 articles | Viewed by 539 | Submission Open

Keywords: forensic pathology; forensic medicine; forensic radiology; forensic genetics; forensic toxicology; postmortem interval; forensic odontology; forensic entomology; forensic anthropology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Computer-Aided Diagnosis and Prognosis of Diseases 2025

edited by

Kenji Suzuki

submission deadline 28 Feb 2026 | Viewed by 497 | Submission Open

Keywords: computer-aided detection and diagnosis; early detection; diagnosis; characterization and intervention; advanced imaging; quantitative imaging; image-guided therapy; personalized medicine; precision medicine; biomarkers; machine/deep learning; radiogenomics; radiomics; computational/artificial intelligence; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics in Maxillofacial Oncology and Trauma

edited by

Ioanna Kalaitsidou

and

Benoît Schaller

submission deadline 28 Feb 2026 | 1 articles | Viewed by 442 | Submission Open

Keywords: maxillofacial diagnostics; craniofacial trauma; oral and maxillofacial oncology; artificial intelligence in imaging; photon-counting CT (PCCT); molecular biomarkers; histopathology; radiomics; multimodal imaging; preoperative planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multidisciplinary Diagnostic Approaches to Infectious Pathologies in Surgical Specialties

edited by

Elena Adelina Toma

and

Octavian Enciu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 413 | Submission Open

Keywords: surgical infections; diagnostic advancements; antimicrobial resistance; molecular diagnostics; radiological imaging; microbiological assays; AI-driven diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Musculoskeletal Radiology

edited by

Jernej Vidmar

submission deadline 28 Feb 2026 | Viewed by 378 | Submission Open

Keywords: musculoskeletal radiology; high-resolution MRI; ultrasound-guided interventions; artificial intelligence in imaging; CT imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging in Cardiomyopathy

edited by

Sophie Mavrogeni

submission deadline 28 Feb 2026 | Viewed by 324 | Submission Open

Keywords: cardiomyopathy; imaging technologies; cardiac MRI; echocardiography; CT; tissue characterization; myocardial fibrosis; disease progression; diagnosis; management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Diagnosis and Management of Oral Cancer: Challenges, Advances, and Multidisciplinary Integration

edited by Eleni A. Georgakopoulou

submission deadline 28 Feb 2026 | Viewed by 291 | Submission Open

Keywords: oral cancer; early diagnosis; oral squamous cell carcinoma; artificial intelligence; oral potentially malignant disorders; multidisciplinary management; tumor board; oral pathology; misinformation; dental screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovative Advances in Diagnosis Through Artificial Intelligence

edited by Jorge Mateo Sotos

submission deadline 28 Feb 2026 | Viewed by 281 | Submission Open

Keywords: artificial intelligence; medical diagnostics; predictive analytics; machine learning; deep learning; digital pathology; early disease detection; personalized medicine; smart healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

The Role of Biomarkers in Alzheimer's Disease

edited by

Ram Sagar

submission deadline 28 Feb 2026 | Viewed by 267 | Submission Open

Keywords: Alzheimer's disease; biomarkers; cerebrospinal fluid proteins; MRI; amyloid imaging; early diagnosis

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence and Big Data in Digestive Healthcare

edited by Hélder Cardoso and

Miguel Mascarenhas

submission deadline 28 Feb 2026 | Viewed by 257 | Submission Open

Keywords: artificial intelligence; big data; digestive system diseases; digestive system neoplasms; electronic health records; endoscopy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Trends and Future Directions in Radiotheragnostic Research: A Special Issue in Collaboration with ISRT 2025

edited by

Kalevi Kairemo

submission deadline 28 Feb 2026 | Viewed by 247 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; targeted alpha therapy; PSMA; prostate cancer; neuroendocrine neoplasms; somatostatin analogs; daughter radionuclides; dosimetry; small-scale/micro-dosimetry; radiobiology; target chemistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Applications of Radiomics and Imaging in Oncology and Cardiovascular Diseases

edited by

Dania Cioni

submission deadline 28 Feb 2026 | Viewed by 218 | Submission Open

Keywords: oncologic imaging; cardiovascular imaging; radiomics; artificial intelligence; machine learning; deep learning; magnetic resonance imaging; computed tomography; nuclear medicine; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging in Acute Respiratory Distress Syndrome

edited by

Denise Battaglini

submission deadline 28 Feb 2026 | Viewed by 209 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); computed tomography (CT); lung ultrasound (LUS); electrical impedance tomography (EIT); positron emission tomography (PET); imaging biomarkers; quantitative imaging analysis; multimodal imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathology and Molecular Diagnosis of Vascular Diseases

edited by

Francisco S. Lozano Sánchez

and María Begoña García-Cenador

submission deadline 28 Feb 2026 | Viewed by 199 | Submission Open

Keywords: vascular pathology; molecular diagnostics; precision medicine; biomarkers; atherosclerosis; thrombosis; vascular imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Artificial Intelligence in Infectious Disease Diagnosis

edited by

Thomas Foster Scherr

submission deadline 28 Feb 2026 | Viewed by 196 | Submission Open

Keywords: infectious diseases; mobile health; machine learning; epidemiology; disease surveillance; diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Human Anatomy—2nd Edition

edited by Ji-Hyun Lee

submission deadline 28 Feb 2026 | Viewed by 177 | Submission Open

Keywords: advanced anatomy; anatomical development; anatomy for diagnostic methods; anatomy and medical technology; anatomical research innovation; anatomical history

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Application of PET/CT in Oncology

edited by

Arvin Haj-Mirzaian

and

Yousef Khazaei Monfared

submission deadline 28 Feb 2026 | Viewed by 157 | Submission Open

Keywords: PET/CT; oncology; cancer imaging; radiotracers; tumor staging; precision medicine; hybrid imaging; artificial intelligence; molecular imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Endoscopic Ultrasound: Diagnostic and Therapeutic Innovations

edited by

Andrada Seicean

submission deadline 28 Feb 2026 | Viewed by 143 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic and therapeutic innovations; minimally invasive interventions; EUS-guided tissue acquisition; advanced imaging techniques; multidisciplinary gastroenterology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pediatric Liver Disease: Emerging Diagnostic Biomarkers, Clinical Management, and Future Directions

edited by Wikrom W. Karnsakul

submission deadline 28 Feb 2026 | Viewed by 132 | Submission Open

Keywords: pediatric liver diseases; early and precise diagnosis; diagnostic biomarker; genetic testing; imaging modalities

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by