High-Performance Computing (HPC) and Computer Architecture

Dear Colleagues, 

High-Performance Computing (HPC) and Computer Architecture are undergoing rapid transformation, shaped by large-scale applications, heterogeneous accelerators, and the convergence of cloud- and supercomputing. At the same time, the rise of AI-driven workloads such as large-scale language model (LLM) training, Mixture-of-Experts (MoE) systems, and other AI-HPC infrastructures is redefining performance requirements and architectural priorities. This Special Issue seeks original research, surveys, and applied contributions that advance our understanding of performance, scalability, and system design across these evolving domains.

Topics of interest include parallel and distributed systems, supercomputing and cluster infrastructures, multi-core and GPU computing, hardware acceleration, quantum-AI computing, and energy-efficient system design. We also welcome work that addresses resource allocation, workload management, programming models, memory and interconnect architectures, and cloud or data center integration. Both theoretical advances and applied research are welcome, provided they deliver clear insights into performance optimization or system-level innovation.

By integrating contributions from both traditional HPC and emerging AI-HPC communities, this Special Issue aims to provide a comprehensive perspective on next-generation computing platforms and inspire solutions for scalable, efficient, and intelligent computation.

Prof. Dr. Taskin Kocak
Dr. Ron (Rongyu) Lin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.