Multicomponent Catalytic Reactions under Green Conditions

Dear colleagues,

Multicomponent Reactions (MCRs), where three or more starting materials are combined together and mostly incorporated in the final product, have a long history and brilliant future in green chemistry. MCRs are precious tools in the hands of a green synthetic chemist. The proper selection of the starting materials, the reaction conditions and the catalyst offer an even greener approach than traditional multicomponent reactions that were originally developed more than a century ago with no awareness of green chemistry principles. In fact, the efficiency, together with both the atom and step economy balance intrinsic to MCRs, can be further improved in addition to the overall greenness of the reaction when MCRs are combined with other environmentally benign synthetic methodologies including shorter and less solvent-intensive purification techniques.

Submissions to this Special Issue on “Multicomponent Reactions under Green Conditions” are welcome in the form of original research papers, reviews or communications that highlight the state of research in the development of novel or revisited Multicomponent Reactions under green conditions, ranging from heterogeneous catalysis to green solvents or solventless conditions, microwave and ultrasound-assisted reactions or any other environmentally-friendly C–C and C–heteroatom bond-forming methodologies following the principles of green and sustainable synthesis.

Prof. Dr. Giovanna Bosica
Guest Editor

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