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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Boron Neutron Capture Therapy (BNCT) for Solid Cancers: (2) Current Advances and Future Perspectives in Clinical Practice

edited by

Yasuaki Ichikawa

and

Tadashi Hanafusa

submission deadline 28 Feb 2027 | Viewed by 69 | Submission Open

Keywords: refractory cancer; boron neutron capture therapy; targeted therapy; good patient QOL; clinical practice

(This special issue belongs to the Section Methods and Technologies Development)

Innovative Approaches in Minimally Invasive and Robotic Surgery for Gastrointestinal Oncology

edited by Maximos Frountzas, Efstathia Liatsou and Dimitrios Katsarelias

submission deadline 28 Feb 2027 | Viewed by 37 | Submission Open

Keywords: robotic surgery; minimally invasive surgery; gastrointestinal oncology; surgical innovation; oncological outcomes; fluorescence-guided surgery

(This special issue belongs to the Section Methods and Technologies Development)

Toll-Like Receptors (TLRs) and Cancer Immunology: Mechanisms, Biomarkers, and Therapeutic Perspectives

edited by

Paulina Mertowska

submission deadline 28 Feb 2027 | Viewed by 35 | Submission Open

Keywords: toll-like receptors; innate immune sensing; cancer immunology; tumor microenvironment; immune evasion; immune checkpoints; biomarkers; cancer immunotherapy; epigenetic regulation; non-coding RNAs

Feature Papers in Section “Methods and Technologies Development” in 2026

edited by

Maxim V. Berezovski

submission deadline 1 Mar 2027 | 4 articles | Viewed by 3858 | Submission Open

Keywords: artificial intelligence (AI); medical imaging; clinical diagnostics; oncology biomarkers; precision medicine; big data integration; early cancer detection; radiomics; therapy response prediction; translational technology

(This special issue belongs to the Section Methods and Technologies Development)

New Advances and Approaches in Thyroid Cancer

edited by

Beatriz Febrero

and José Manuel Rodríguez

submission deadline 1 Mar 2027 | 2 articles | Viewed by 3196 | Submission Open

Keywords: thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; follicular thyroid cancer; poorly differentiated thyroid tumours; novel approaches; prognostic biomarkers; risk stratification

(This special issue belongs to the Section Cancer Therapy)

Novel Developments in Invasive Lobular Breast Cancer: Diagnosis, Prognosis and Therapy (2nd Edition)

edited by

Lubna Khaldi

and

Nektarios Koufopoulos

submission deadline 1 Mar 2027 | 1 articles | Viewed by 1490 | Submission Open

Keywords: invasive lobular carcinoma; imaging; diagnosis; pathology; tumor microenvironment; treatment; metastasis

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Endoscopic Management of Esophageal Cancer

edited by Hugo Uchima and

Cristina Bugés Sánchez

submission deadline 1 Mar 2027 | 1 articles | Viewed by 1070 | Submission Open

Keywords: endoscopic submucosal dissection (ESD); esophageal squamous cell carcinoma; Barrett’s esophagus

(This special issue belongs to the Section Cancer Therapy)

Precise and Personalized Radiation Therapy for Cancer Treatment

edited by Thomas Weissmann and

Michael Goldstein

submission deadline 1 Mar 2027 | Viewed by 336 | Submission Open

Keywords: radiation research; artificial intelligence; cancer; adaptive radiotherapy; stereotactic radiotherapy; radiotherapy; (radio)-immunotherapy; (radio)-chemotherapy; precision radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Primary and Recurrent Gynecological Cancer: Epidemiology, Management and New Therapies

edited by Nithya Ratnavelu and Ioannis Biliatis

submission deadline 5 Mar 2027 | 5 articles | Viewed by 20898 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; vulva cancer; vaginal cancer; gynecological cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Symptom Management in Cancer Care

edited by Lena Lee and Joosun Shin

submission deadline 5 Mar 2027 | Viewed by 419 | Submission Open

Keywords: symptom burden; symptom management; health service; palliative care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Ovarian Cancer: Pathogenesis, Molecular Mechanism and Opportunities for Interventions

edited by

Apriliana Kartikasari

submission deadline 10 Mar 2027 | 2 articles | Viewed by 4004 | Submission Open

Keywords: ovarian cancer; pathogenesis; therapy; biomarkers; molecular

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

The Molecular Pathogenesis of Lung Cancer: From Oncogenic Drivers to Tumor Microenvironment

edited by

Bin Xu

submission deadline 12 Mar 2027 | Viewed by 334 | Submission Open

Keywords: lung cancer; oncogenic drivers; tumor microenvironment; immune checkpoint inhibitors; immunotherapy resistance; predictive biomarkers

(This special issue belongs to the Section Cancer Pathophysiology)

Extracellular Vesicles in Cancer: Biology, Biomarkers and Therapeutic Applications

edited by

Nathan Wall

submission deadline 12 Mar 2027 | Viewed by 68 | Submission Open

Keywords: extracellular vesicles; exosomes; biomarker; liquid biopsy; tumor microenvironment

Clinical, Immune, and Microbial Markers of Response to Systemic Therapy in Skin Cancer

edited by

Robin Reschke

submission deadline 14 Mar 2027 | 1 articles | Viewed by 921 | Submission Open

Keywords: melanoma; cutaneous squamous cell carcinoma; immunotherapy; immune checkpoint inhibitors; tumor microenvironment; microbiome; predictive biomarkers

Contemporary Management of Urologic Cancers

edited by

Ruben Blachman-Braun

and Hangcheng Fu

submission deadline 14 Mar 2027 | Viewed by 138 | Submission Open

Keywords: urologic oncology; prostate cancer; kidney cancer; bladder cancer; testicular cancer; penile cancer; upper urinary tract cancer; focal therapy; cancer survivorship; robotic surgery

(This special issue belongs to the Section Cancer Therapy)

Proton Therapy of Cancer Treatment

edited by Minglei Kang, Benjamin Durkee and Kuo Men

submission deadline 15 Mar 2027 | 5 articles | Viewed by 9617 | Submission Open

Keywords: proton therapy; FLASH radiotherapy; upright; pediatric cancer; head and neck cancer; affordable proton solutions; adaptive radiation therapy; treatment planning optimization; proton system commissioning

(This special issue belongs to the Section Cancer Therapy)

Advances in Bone Metastasis Research: From Mechanisms to Therapy

edited by Ye Lin

submission deadline 15 Mar 2027 | 1 articles | Viewed by 2476 | Submission Open

Keywords: bone metastasis; tumour microenvironment; biomarker; targeted therapy; detection; palliative care

(This special issue belongs to the Section Cancer Metastasis)

The Clinical, Technological, and Scientific Progress of Boron Neutron Capture Therapy

edited by

Shinji Kawabata

submission deadline 15 Mar 2027 | Viewed by 1530 | Submission Open

Keywords: boron neutron capture therapy (BNCT); neutron capture therapy (NCT); accelerator-based neutron source; neutron dosimetry; boron drug development; alternative capture agents; radiobiological effects; radiation oncology; interdisciplinary research; clinical translation

(This special issue belongs to the Section Cancer Therapy)

New Models of Cancer Care to Improve Patient Experiences and Clinical Outcomes

edited by

Manali I. Patel

submission deadline 15 Mar 2027 | 1 articles | Viewed by 1260 | Submission Open

Keywords: patient-centered care; community-based interventions; innovative care models; digital health solutions; patient engagement; clinical outcomes; value-based cancer care

Resistance in Lung Cancer

edited by Mohamed Gadelkarim

submission deadline 15 Mar 2027 | Viewed by 634 | Submission Open

Keywords: lung cancer; SCLC; NSCLC; drug resistance; genetic mutations; tumor microenvironment; EMT; biomarkers; targeted therapy; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

The Critical Intersection of Tobacco Use and Cancer Care

edited by Irene Tamí-Maury

submission deadline 15 Mar 2027 | Viewed by 418 | Submission Open

Keywords: cancer; oncology settings; smoking; tobacco use; prevention; cessation

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Robotic and Laparoscopic Techniques for Urologic Cancers: Innovations in Resection and Reconstruction

edited by

Tobias Klatte

submission deadline 15 Mar 2027 | Viewed by 326 | Submission Open

Keywords: robot-assisted surgery; surgical robotics; minimally invasive surgery; artificial intelligence; complications; prognostic and predictive factors; planning; perioperative care

(This special issue belongs to the Section Methods and Technologies Development)

Aptamers Against Cancer

edited by

Anna Kichkailo

and

Liubov A. Osminkina

submission deadline 15 Mar 2027 | Viewed by 269 | Submission Open

Keywords: aptamers; cancer theranostics; targeted therapy; biosensors; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Clinical Update on Lung Cancer: Current Strategies and Outcome

edited by Antonio D'Andrilli

submission deadline 15 Mar 2027 | Viewed by 262 | Submission Open

Keywords: lung cancer; clinical outcomes; diagnosis; treatment

Integrative Cancer Genomics: From Classical Cytogenetics to Emerging Molecular Technologies

edited by Ying S. Zou

submission deadline 15 Mar 2027 | Viewed by 225 | Submission Open

Keywords: integrative cancer genomics; cancer cytogenetics; molecular cytogenetics; chromosomal abnormalities; optical genome mapping; next-generation sequencing; nanopore sequencing; 3D/Hi-C technologies; structural variants; AI in cytogenetics; hematological malignancies; FISH; chromosomal microarray; solid tumors

(This special issue belongs to the Section Methods and Technologies Development)

Mesothelioma Environmental Risk Factors and Epidemiological and Biological Insights

edited by Sonja Klebe

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1372 | Submission Open

Keywords: mesothelioma; asbestos; mesothelial proliferation; therapy; marker

Advances in Clinical, Diagnostic and Neurosurgical Management in Pediatric Neuro-Oncology

edited by

John Ross Crawford

and Michael Levy

submission deadline 20 Mar 2027 | Viewed by 449 | Submission Open

Keywords: neuro-oncology; brain tumors; neuroradiology; proton therapy; pediatric; neurosurgery; treatment; chemotherapy; targeted agents; molecular subtypes; immunotherapy; late effects; radiation therapy

(This special issue belongs to the Section Pediatric Oncology)

Inflammatory Bowel Disease and Cancers: What Connections Lie Between Them?

edited by

Ferdinando D'Amico

submission deadline 20 Mar 2027 | Viewed by 198 | Submission Open

Keywords: inflammatory bowel disease; Crohn’s disease; ulcerative colitis; cancers

From Bench to Bedside: Systemic Therapy in Renal Cell Carcinoma

edited by Hailiang Zhang

submission deadline 20 Mar 2027 | Viewed by 76 | Submission Open

Keywords: renal cell carcinoma; systemic therapy; immune checkpoint inhibitors; targeted therapy; tumor microenvironment; biomarkers; precision oncology; translational research

(This special issue belongs to the Section Cancer Therapy)

Image Assisted High Precision Radiation Oncology

edited by Christopher Njeh and

Senthamizhchelvan Srinivasan

submission deadline 25 Mar 2027 | 4 articles | Viewed by 4338 | Submission Open

Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT, MRI, PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration

(This special issue belongs to the Section Methods and Technologies Development)

Feature Papers in Section “Infectious Agents and Cancer”

edited by

Massimiliano Berretta

submission deadline 25 Mar 2027 | 2 articles | Viewed by 1170 | Submission Open

Keywords: infectious agents; microbiota; biomarker; oncology; cancers

(This special issue belongs to the Section Infectious Agents and Cancer)

Imaging-Based Cancer Radiotherapy

edited by

Fariba Tohidinezhad

and Alberto Traverso

submission deadline 25 Mar 2027 | 1 articles | Viewed by 747 | Submission Open

Keywords: radiotherapy; imaging biomarkers; artificial intelligence; radiomics; toxicity prediction; adaptive radiotherapy; automated treatment planning; image-guided radiotherapy; multimodal learning; precision oncology

(This special issue belongs to the Section Methods and Technologies Development)

Smart Nanotechnology for Drug Delivery in Cancer Therapy

edited by

Stefano Leporatti

submission deadline 30 Mar 2027 | 1 articles | Viewed by 2687 | Submission Open

Keywords: nanotechnology; drug delivery; cancer therapy; nanocarriers; nanoparticles; nano-devices; nano-channels

(This special issue belongs to the Section Methods and Technologies Development)

Brachytherapy in the Treatment of Gynaecological Malignancies

edited by

Alina E. Sturdza

submission deadline 30 Mar 2027 | 2 articles | Viewed by 1710 | Submission Open

Keywords: image-guided brachytherapy; gynecological malignancies; reirradiation using brachytherapy; cervical cancer; endometrial cancer; vulva/vagina cancer; cancer in the elderly; brachy education

(This special issue belongs to the Section Cancer Therapy)

Radiation Therapy for Meningiomas

edited by Helen A. Shih and Lia M. Halasz

submission deadline 30 Mar 2027 | 1 articles | Viewed by 852 | Submission Open

Keywords: radiation therapy; proton radiation; particle therapy; theranostics; brachytherapy; molecular features; advance imaging; late toxicities; quality of life

(This special issue belongs to the Section Cancer Therapy)

Genome Instability, Ubiquitin Signaling and Cancer Therapy

edited by

Sehbanul Islam

and Aftab Alam

submission deadline 30 Mar 2027 | Viewed by 291 | Submission Open

Keywords: DNA damage response; DNA repair; replication stress; ubiquitin–proteasome system; E3 ubiquitin ligases; targeted protein degradation; cell cycle checkpoints; drug resistance

Leukemia Stem Cells: Persistence, Resistance, and Novel Eradication Strategies

edited by Elisa Donato and Darja Karpova

submission deadline 30 Mar 2027 | Viewed by 284 | Submission Open

Keywords: leukemia stem cells (LSCs); acute myeloid leukemia (AML); therapeutic resistance; minimal residual disease (MRD); LSC quiescence; cellular therapy; hematopoietic stem cell transplantation (HSCT); LSC microenvironment

Reproductive and Hormonal Factors in Breast and Gynecological Cancers: Epidemiological, Pathological, Diagnostic, and Therapeutic Perspectives

edited by

Raluca Anca Balan

submission deadline 30 Mar 2027 | Viewed by 246 | Submission Open

Keywords: breast cancer; gynecological cancers; reproductive factors; hormonal exposure; epidemiology; tumor pathology; molecular subtypes; biomarkers; early diagnosis; risk stratification; endocrine therapy; targeted therapy; treatment resistance; personalized medicine

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Ovarian Cancer Research and Treatment: 2nd Edition

edited by

Maria Barbolina

submission deadline 31 Mar 2027 | 9 articles | Viewed by 15645 | Submission Open

Keywords: ovarian carcinoma metastasis; mechanisms of dissemination; chemotherapy resistance; novel treatments and therapeutic approaches; novel molecular targets

(This special issue belongs to the Section Cancer Therapy)

Clinical Treatment and Prognosis of Breast Cancer

edited by Roxana Popescu and

Ionut Marcel Cobec

submission deadline 31 Mar 2027 | 5 articles | Viewed by 13384 | Submission Open

Keywords: breast cancer; targeted therapy; personalized therapy; alternative approach; tumor biology; gynecologic oncology

(This special issue belongs to the Section Clinical Research in Cancer)

Decision-Making Biomarkers in the Treatment of Hepatocellular Carcinoma

edited by

Norihiro Imai

and

Dongming Liu

submission deadline 31 Mar 2027 | 5 articles | Viewed by 11972 | Submission Open

Keywords: hepatocellular carcinoma; borderline resectable; conversion therapy; neoadjuvant therapy; immunotherapy; immune-related adverse event; molecular-targeted agent

(This special issue belongs to the Section Cancer Biomarkers)

Urological Cancer: Epidemiology and Genetics

edited by Ilir Agalliu and Evan Kovac

submission deadline 31 Mar 2027 | 3 articles | Viewed by 7621 | Submission Open

Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Hybrid Molecular Imaging Approaches in Cancer: PET/CT, PET/MRI, and Beyond

edited by

Luca Urso

submission deadline 31 Mar 2027 | 3 articles | Viewed by 4095 | Submission Open

Keywords: PET/CT; PET/MRI; hybrid molecular imaging; radiomics and artificial intelligence; conventional PET Radiotracers; emerging PET Radiotracers; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Acute Myeloid Leukemia in Adults (2nd Edition)

edited by

Theodoros Karantanos

submission deadline 31 Mar 2027 | 3 articles | Viewed by 4088 | Submission Open

Keywords: acute myeloid leukemia; molecular biology; treatment landscape; resistance mechanisms

(This special issue belongs to the Section Clinical Research in Cancer)

Pancreatic Neoplasms in the 21st Century: Challenges and Opportunities in Diagnosis and Management

edited by

Beata Jabłońska

submission deadline 31 Mar 2027 | 4 articles | Viewed by 3693 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDCA); pancreatic mucinous cystic neoplasm (MCN); pancreatic intraductal papillary mucinous neoplasm (IPMN); pancreatic serous cystic neoplasm (SCN); pancreatic solid pseudopapillary neoplasm (SPN); pancreatic neuroendocrine tumor (PNET); pancreatectomy; pancreatic resection

Treatment of Acute Kidney Injury in Cancer Patients: From Theory to Practice

edited by

Umut Selamet

and Shveta S. Motwani

submission deadline 31 Mar 2027 | 2 articles | Viewed by 3588 | Submission Open

Keywords: immune check point inhibitor related nephritis; MGRS; CART cell therapy; stem cell transplant; TMA; BK nephropathy; cisplatin nephropathy

(This special issue belongs to the Section Cancer Therapy)

The Role of Flow Cytometry in Hematologic Malignancies

edited by

Kristy Wolniak

and Lucy Fu

submission deadline 31 Mar 2027 | 1 articles | Viewed by 3052 | Submission Open

Keywords: flow cytometry; hematology; oncology; malignancy; lymphoma; leukemia; pathology; innovation; methodology; diagnosis

(This special issue belongs to the Section Methods and Technologies Development)

Innovations in Colorectal Cancer

edited by Sandy Hwang Fang

submission deadline 31 Mar 2027 | 3 articles | Viewed by 2587 | Submission Open

Keywords: colon cancer; rectal cancer; innovation; clinical trials; total neoadjuvant therapy; medical oncology; radiation oncology

From Molecular Genomics and the Tumor Microenvironment to Precision Diagnosis and Therapy in Liver Cancer

edited by

Daniel Wai Hung Ho

and Yuman Tsui

submission deadline 31 Mar 2027 | 2 articles | Viewed by 2094 | Submission Open

Keywords: tumor heterogeneity; cancer genomics; sequencing; molecular landscapes; tumor microenvironment; cancer stem cell; liquid biopsy; diagnostics; biomarker; treatment and resistance

Integrating Imaging AI into Glioma Clinical Workflows: Deployment, Technical Challenges and Real-World Impact

edited by

Sotirios Bisdas

and Loizos Siakallis

submission deadline 31 Mar 2027 | 2 articles | Viewed by 1994 | Submission Open

Keywords: gliomas; glioblastomas; imaging; MRI; CT; PET; AI; clinical workflow integration; neuro-oncologic care; radiation therapy

(This special issue belongs to the Section Methods and Technologies Development)

Displaying special issue 801-850 on page 17 of 22.

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