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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnostics and Treatments for Glioblastoma

edited by Sied Kebir and

Manmeet Singh Ahluwalia

submission deadline 10 Apr 2026 | 1 articles | Viewed by 604 | Submission Open

Keywords: glioblastoma; molecular diagnostics; neuro-oncology; imaging biomarkers; immunotherapy; targeted therapy; tumor-treating fields; radiotherapy; chemotherapy; translational research; machine learning; positron emission tomography

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Radiation Therapy in Lung Cancer: From a Technical Revolution to a Combination with New Systemic Approaches (2nd Edition)

edited by

Alessio Bruni

submission deadline 10 Apr 2026 | Viewed by 314 | Submission Open

Keywords: NSCLC; SCLC; radiation therapy; SBRT; adjuvant RT; immunotherapy; concomitant treatments; toxicities

(This special issue belongs to the Section Cancer Therapy)

Endothelial Cells in Inflammation, Tissue Repair, Ageing and Cancer: 2nd Edition

edited by

Constantinos Mikelis

submission deadline 10 Apr 2026 | Viewed by 285 | Submission Open

Keywords: ageing; angiogenesis; cancer; cytokines; endothelial cells; growth factors; inflammation; tissue repair

(This special issue belongs to the Section Tumor Microenvironment)

Neurosurgery Research on Brain Tumors

edited by

Toshihide Tanaka

submission deadline 10 Apr 2026 | Viewed by 132 | Submission Open

Keywords: neuro-oncology; neurosurgical technique; brain tumors; neuroimages

Oncology: State-of-the-Art Research in Austria

edited by

Bahil Ghanim

and

Mir Alireza Hoda

submission deadline 15 Apr 2026 | 3 articles | Viewed by 9420 | Submission Open

Keywords: oncology; cancer; research; tumor; Austria

(This special issue belongs to the Section Cancer Therapy)

The Bone Marrow Microenvironment in Myelodysplastic Syndromes—Pathogenesis, Immune Evasion, and Therapeutic Opportunities

edited by

Ciro Roberto Rinaldi

submission deadline 15 Apr 2026 | Viewed by 2785 | Submission Open

Keywords: myelodysplastic syndromes; bone marrow microenvironment; hematopoietic stem cells; mesenchymal stromal cells; immune evasion; CD47; calreticulin; inflammatory cytokines; clonal hematopoiesis; microenvironment-targeted therapy

(This special issue belongs to the Section Tumor Microenvironment)

Detection of Breast Cancer with Mammography

edited by

Luca Nicosia

submission deadline 15 Apr 2026 | 1 articles | Viewed by 2147 | Submission Open

Keywords: mammography; breast cancer detection; imaging technologies; artificial intelligence; radiomics

(This special issue belongs to the Section Methods and Technologies Development)

Advanced Insights into the Etiology of Lymphoma

edited by Susan L. Slager and James R. Cerhan

submission deadline 15 Apr 2026 | 2 articles | Viewed by 1049 | Submission Open

Keywords: lymphoma etiology; genetic predisposition; clonal hematopoiesis; precursor conditions; risk stratification; viral oncogenesis; non-Hodgkin lymphoma; Hodgkin lymphoma

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Cellular Heterogeneity and Plasticity in the Tumor Microenvironment

edited by

Loredana Albonici

and

Manuel Scimeca

submission deadline 15 Apr 2026 | 1 articles | Viewed by 980 | Submission Open

Keywords: tumor microenvironment (TME); tumor microenvironmental heterogeneity and drug resistance; cancer cell plasticity and immune evasion; epithelial– mesenchymal transition (EMT); tumor immune context

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Radiation Therapy for Brain Metastases

edited by Luis A. Pérez-Romasanta

submission deadline 15 Apr 2026 | 1 articles | Viewed by 512 | Submission Open

Keywords: brain metastasis; metastatic brain tumor; imaging; radiotherapy; stereotactic radiosurgery; radiomics; machine learning; magnetic resonance imaging; positron emission tomography

(This special issue belongs to the Section Cancer Therapy)

Recent Advances in Radiological Imaging for Head and Neck Squamous Cell Carcinoma

edited by Mintu Nath and

Fergus McKiddie

submission deadline 15 Apr 2026 | Viewed by 307 | Submission Open

Keywords: head and neck squamous cell carcinoma; computed tomography (CT); positron emission tomography (PET); PET-CT; radiological imaging; image processing; image segmentation; diagnosis; treatment modalities; prediction and prognostic models; mathematical and statistical models; machine learning and deep learning techniques

(This special issue belongs to the Section Methods and Technologies Development)

Brain Tumors—Related Cognitive Impairment

edited by

Djaina Satoer

and

Anne Marie Buunk

submission deadline 15 Apr 2026 | Viewed by 194 | Submission Open

Keywords: aphasia; cognition; brain tumor; surgery; adjuvant treatment; rehabilitation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

State-of-the-Art Surgical Treatment for Lung Cancers

edited by

Andrea Axtell

and

Malcolm DeCamp

submission deadline 15 Apr 2026 | Viewed by 149 | Submission Open

Keywords: lung cancer; lung cancer surgery; sublobar resection; segmentectomy; minimally invasive surgery; robotic surgery; tumor localization; mediastinal staging

(This special issue belongs to the Section Cancer Therapy)

Clinical and Molecular Biomarkers in Breast Cancer Management

edited by Zahi I. Mitri

submission deadline 15 Apr 2026 | Viewed by 102 | Submission Open

Keywords: prognostic biomarkers; predictive biomarkers; molecular assays; therapeutics; special situations in breast cancer

(This special issue belongs to the Section Cancer Biomarkers)

Prostate Cancer: Molecular Imaging and Magnetic Resonance Imaging (MRI)

edited by Marco Paciotti and Davide Maffei

submission deadline 17 Apr 2026 | 5 articles | Viewed by 9729 | Submission Open

Keywords: prostate cancer; prostate imaging; diagnosis; clinical staging; magnetic resonance imaging (MRI); fusion biopsy; molecular imaging; positron emission tomography (PET); PSMA PET/CT; PSMA-based therapy

(This special issue belongs to the Section Methods and Technologies Development)

Unique Perspectives in Cancer Signaling (2nd Edition)

edited by

Peiwen Fei

submission deadline 18 Apr 2026 | 1 articles | Viewed by 1082 | Submission Open

Keywords: oncogenesis; cancer signaling; technology; translational; clinical; epidemiology

(This special issue belongs to the Section Cancer Therapy)

Immune Landscape of Renal Cell Carcinoma

edited by

Scott S. Tykodi

and Yuexin Xu

submission deadline 20 Apr 2026 | 4 articles | Viewed by 13291 | Submission Open

Keywords: renal cell carcinoma; solid tumor; immunotherapy; immune checkpoint inhibitor; T cell; tumor microenvironment; biomarkers; tumor antigen; immune surveillance

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advancements in Child, Adolescent, and Young Adult Cancer Survivorship

edited by

Juan A. Ortega-García

submission deadline 20 Apr 2026 | 5 articles | Viewed by 11306 | Submission Open

Keywords: late effects; chronic diseases; prevention; rehabilitation; remediation; psychosocial factors; quality of life; lifestyles; surveillance; survivors; educational strategies

(This special issue belongs to the Section Pediatric Oncology)

Immunotherapy and Transplantation in the Era of Transplant Oncology (2nd Edition)

edited by

Maen Abdelrahim

submission deadline 20 Apr 2026 | Viewed by 139 | Submission Open

Keywords: transplant oncology; liver transplantation; solid organ transplantation; hepatocellular carcinoma; immunotherapy; immune-checkpoint inhibitors; CTLA-4 inhibitors; PD-1 inhibitors; allograft rejection

(This special issue belongs to the Section Transplant Oncology)

Thyroid Cancer Recurrence: Integrating Surgical, Clinical, and Translational Research

edited by

Nikola Slijepcevic

and Ioannis Koutelidakis

submission deadline 20 Apr 2026 | Viewed by 96 | Submission Open

Keywords: thyroid cancer; recurrence; surgery; clinical management; aggressive subtypes; rare subtypes; biomarkers; imaging; translational research; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Research on Current Progress in Penile Cancer

edited by Juan J. Chipollini and Ahmet Murat Aydin

submission deadline 25 Apr 2026 | 4 articles | Viewed by 14497 | Submission Open

(This special issue belongs to the Section Cancer Therapy)

Hepatocellular Carcinoma: Current Treatment Strategies for Advanced Disease and Recurrence: 2nd Edition

edited by

Takefumi Kimura

submission deadline 25 Apr 2026 | 2 articles | Viewed by 4309 | Submission Open

Keywords: hepatocellular carcinoma; surgery; anticancer drugs; radiation therapy; recurrence

(This special issue belongs to the Section Cancer Therapy)

Clinical Applications of Integrative Analysis of Validated Somatic and Germline Genomic Results in Oncology

edited by

Arezou A. Ghazani

submission deadline 25 Apr 2026 | 1 articles | Viewed by 3934 | Submission Open

Keywords: tumor and constitutional genome integration; clinical application of somatic and germline findings; precision oncology

(This special issue belongs to the Section Molecular Cancer Biology)

PD-1/PD-L1 Immune Checkpoint Therapy: From Predictive Biomarkers to Noninvasive Imaging 2nd Edition

edited by

Patrizia Ferroni

Fiorella Guadagni

and

Mario Roselli

submission deadline 25 Apr 2026 | Viewed by 440 | Submission Open

Keywords: PD-1; PD-L1; anti-cancer immune response; immune checkpoint; immunotherapy; biomarker; immuno-PET radiotracers; drug combinations

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Clinical Benefit of Hybrid PET/MRI Molecular Imaging in Oncology

edited by Ana María García-Vicente and

Edel Noriega-Álvarez

submission deadline 25 Apr 2026 | Viewed by 130 | Submission Open

Keywords: PET/MRI; hybrid imaging; gynecological cancer; prostate cancer; glioma; brain metastases; brain meningioma; sarcoma; liver cancer; hepato-biliary cancer; pancreatic cancer; rectal cancer; breast cancer

(This special issue belongs to the Section Clinical Research of Cancer)

Surgical Treatment of Hepato-Pancreato-Biliary Cancers

edited by Mariano C. Giglio

submission deadline 27 Apr 2026 | 1 articles | Viewed by 1789 | Submission Open

Keywords: pancreatic cancer; hepatocellular carcinoma; colorectal liver metastases; liver surgery; pancreatic surgery; hepato-biliary cancers

(This special issue belongs to the Section Cancer Therapy)

Head and Neck Cancer: Advanced PET/CT and MRI Imaging with a Focus on Current and Emerging Molecular Theranostics

edited by Bennett Chin, Jorge Oldan and Steven P. Rowe

submission deadline 28 Apr 2026 | 6 articles | Viewed by 18492 | Submission Open

Keywords: head and neck cancer; thyroid cancer; PET/SPECT/CT molecular imaging; radionuclide therapy; nuclear medicine

(This special issue belongs to the Section Cancer Therapy)

Immune Biomarkers in Solid Tumors: From Peripheral Blood Parameters to Tissue-Based Indicators for Prognosis and Therapy Response

edited by

Ioannis P. Trontzas

and

Konstantinos Syrigos

submission deadline 28 Apr 2026 | 2 articles | Viewed by 3640 | Submission Open

Keywords: immune biomarkers; solid tumors; peripheral blood immune parameters; circulating immune cells; cytokines; tissue-based biomarkers; immune checkpoint molecules; prognostic biomarkers; predictive biomarkers; tumor microenvironment; immunotherapy response; translational oncology

(This special issue belongs to the Section Cancer Biomarkers)

Novel Therapeutic Strategies in Salivary Gland Tumor

edited by

Giovanni Salzano

Arianna Di Stadio

and

Luigi Angelo Vaira

submission deadline 30 Apr 2026 | 8 articles | Viewed by 21608 | Submission Open

Keywords: parotid gland; parotid tumors; facial nerve; novel therapeutic options; distant metastasis; liquid biopsy; prognostic factors; parotid robotic surgery; microRNA; imaging

(This special issue belongs to the Section Cancer Therapy)

Advancements in Molecular Research of Prostate Cancer

edited by

Anait S. Levenson

submission deadline 30 Apr 2026 | 7 articles | Viewed by 16517 | Submission Open

Keywords: prostate cancer; molecular targets; tumor heterogeneity; targeted interception and therapies; noninvasive biomarkers; precision oncology

(This special issue belongs to the Section Molecular Cancer Biology)

Immune Microenvironment and Immunotherapy in Malignant Brain Tumors

edited by Masaki Terabe and

Mark R. Gilbert

submission deadline 30 Apr 2026 | 5 articles | Viewed by 14901 | Submission Open

Keywords: glioma; brain metastasis; primary brain cancer; tumor immunity; neuroimmunology; immune microenvi-ronment; T cells; myeloid cells; cancer neuroscience

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Uveal Melanoma

edited by

Takami Sato

and

Mizue Terai

submission deadline 30 Apr 2026 | 7 articles | Viewed by 13259 | Submission Open

Keywords: uveal melanoma; eye cancer; liver metastasis; Gα q/11 mutations; BAP1; SF3B1; PRAME; dormancy; liver-directed treatment; T-cell engager

(This special issue belongs to the Section Molecular Cancer Biology)

Quality of Life and Management of Pediatric Cancer

edited by

Luca Giacomelli

and

Momcilo Jankovic

submission deadline 30 Apr 2026 | 5 articles | Viewed by 11760 | Submission Open

Keywords: pediatric palliative care; oncology; quality of life; early management

(This special issue belongs to the Section Pediatric Oncology)

The Future of Machine Learning in Predicting the Treatment Responses of Cancers

edited by Alfredo Vellido,

Ana Candiota

and

Margarida Julia-Sape

submission deadline 30 Apr 2026 | 4 articles | Viewed by 11586 | Submission Open

Keywords: cancer treatment response; medical decision support systems; cancer outcome prediction; personalized medicine; pre-clinical models; artificial intelligence; machine learning; deep learning; progression-free survival; disease-free survival; event-free survival; overall survival; adverse event; quality of life; surrogate endpoint

(This special issue belongs to the Section Methods and Technologies Development)

Human Microbiome, Diet and Cancerogenesis

edited by Ewa Brzeziańska-Lasota

submission deadline 30 Apr 2026 | 3 articles | Viewed by 10934 | Submission Open

Keywords: microbiota; dysbiosis; oncobiome; cell disruptors; cell signaling; epigenetics; diet; dietary intervention; microbiota disorders; cancerogenesis

(This special issue belongs to the Section Tumor Microenvironment)

Targeted Therapy in Head and Neck Cancer

edited by

Pietro De Luca

, Angelo Camaioni and Luca de Campora

submission deadline 30 Apr 2026 | 5 articles | Viewed by 10312 | Submission Open

Keywords: salivary glands; thyroid; laryngeal cancer; molecular oncology; reconstruction; microsurgery; oral cancer; HPV; oropharyngeal cancer

(This special issue belongs to the Section Cancer Therapy)

Epidemiology of Cancer and Risk Factors: Pushing Boundaries in Public Health Research and Policy

edited by

The Phuong Nguyen

submission deadline 30 Apr 2026 | 5 articles | Viewed by 8469 | Submission Open

Keywords: cancer epidemiology; risk factors; public health policy; cancer prevention; early detection; genetic determinants; environmental exposures; behavioral health; interdisciplinary approaches; innovative methodologies

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Prognosis and Treatment of Cutaneous Melanoma (2nd Edition)

edited by

Eduardo Nagore

submission deadline 30 Apr 2026 | 3 articles | Viewed by 8366 | Submission Open

Keywords: prognosis; melanoma; adjuvant; germline; somatic; genetic; epigenetic; neoadjuvant

(This special issue belongs to the Section Cancer Therapy)

Surgical Oncology for Hepato-Pancreato-Biliary Cancer

edited by Zaed Z. R. Hamady

submission deadline 30 Apr 2026 | 6 articles | Viewed by 7519 | Submission Open

Keywords: pancreatic cancer; liver cancer; liver metastases; surgical oncology; multidisciplinary approach

(This special issue belongs to the Section Clinical Research of Cancer)

Neuroblastoma: Molecular Insights and Clinical Implications

edited by Mary Beth Madonna

submission deadline 30 Apr 2026 | 2 articles | Viewed by 7108 | Submission Open

Keywords: neuroblastoma; molecular mechanisms; targeted therapies; immunotherapies; small molecule therapies

(This special issue belongs to the Section Molecular Cancer Biology)

Radiomics in Cancer Imaging: Theory and Applications in Solid Tumours

edited by

Francesco Bianconi

and

Barbara Palumbo

submission deadline 30 Apr 2026 | 3 articles | Viewed by 6624 | Submission Open

Keywords: radiomics for the diagnosis; prognostication and treatment planning of solid tumours; methods; translational research and clinical applications; conventional and deep learning radiomics; interpretability of radiomics features and prediction models; image processing (including acquisition; segmentation and feature extraction); imaging methods (including CT; MRI; PET; SPECT and US)

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Combination Therapy in Lymphoma

edited by

Afua Adjeiwaa Mensah

and Alberto Arribas

submission deadline 30 Apr 2026 | 2 articles | Viewed by 6073 | Submission Open

Keywords: combination therapy; non-Hodgkin lymphoma; Hodgkin lymphoma; targeted agents; antibody drug conjugates; bispecific agents; cellular therapies; immune checkpoint inhibitors and epigenetic agents

(This special issue belongs to the Section Cancer Therapy)

Mesothelioma Epidemiology, Pathogenesis, Emerging Treatments and Pre-Clinical Models

edited by

Francesca Pentimalli

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3833 | Submission Open

Keywords: mesothelioma; epidemiology; pathogenesis; emerging treatments; risk factors; biomarkers; surgical techniques; targeted therapies; immunotherapies; pre-clinical models

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Integrating Bioinformatics, AI, Imaging, and Clinical Informatics in Cancer Research

edited by Jason Li

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3602 | Submission Open

Keywords: bioinformatics; multiomics; genomics; transcriptomics artificial intelligence; deep learning; clinical informatics; medical imaging; functional genomics; multi-discipline

(This special issue belongs to the Section Cancer Informatics and Big Data)

Acute Myeloid Leukemia: Updates on Diagnosis, Treatment and Management

edited by

Francesco Lanza

and

Giovanni Marconi

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3590 | Submission Open

Keywords: acute myeloid leukemia; treatment; targeted therapy; molecular profiling; resistance

(This special issue belongs to the Section Methods and Technologies Development)

Cancer Immunotherapy as Part of Precision Clinical Medicine

edited by

Peter Lang

and

Christo Kole

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3498 | Submission Open

Keywords: cancer; immunotherapy; tumor microenvironment; molecular biology and genetics

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Interrogating Molecular Regulators and Chemical Agents in Brain Tumor Progression

edited by Shilpi Singh

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3488 | Submission Open

Keywords: brain tumor progression; molecular mechanisms; small molecule inhibitors; natural compounds; synthetic drugs; biomarkers; oncogenic pathways; metabolic reprogramming

(This special issue belongs to the Section Tumor Microenvironment)

Molecular PET Imaging in Cancer Metabolic Studies

edited by

Aditi Mulgaonkar

and

Sashi Debnath

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3361 | Submission Open

Keywords: PET imaging; PET/CT; PET/MRI; cancer metabolism; tumor microenvironment; cancer antigens; radiotracers

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Molecular and Genetic Biomarkers in Head and Neck Squamous Cell Carcinoma

edited by

Joanna Katarzyna Strzelczyk

and Michal Masternak

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3357 | Submission Open

Keywords: head and neck squamous cell carcinoma (HNSCC); molecular biomarkers; genetic biomarkers; multi-omics approaches; HNSCC carcinogenesis; prognostic biomarkers; translational medicine; molecular pathology

(This special issue belongs to the Section Molecular Cancer Biology)

Health Disparities and Outcomes in Cancer Survivors

edited by

Claire Jungyoun Han

submission deadline 30 Apr 2026 | 3 articles | Viewed by 2823 | Submission Open

Keywords: cancer survivorship; quality of life; social behavioral determinants of health (SBDH); health disparities; symptom management

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Displaying special issue 451-500 on page 10 of 24.

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