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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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AI-Driven Integration of Multimodal Imaging and Clinical Data for Long COVID: Mapping Brain-Behavior Associations and Treatment Outcomes

edited by

Thorsten Rudroff

and

Riku Klén

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1563 | Submission Open

Keywords: artificial intelligence ; neuroinflammation ; cognitive dysfunction ; multimodal imaging ; neural connectivity ; deep learning ; neurocognitive assessment

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Novel Insights into Pediatric Dystonia and Childhood-Onset Movement

edited by

Terence Sanger

submission deadline 21 Jul 2025 | Viewed by 362 | Submission Open

Keywords: basal ganglia function; movement disorders; theories and models; clinical research

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Psychiatry and Addiction: A Multi-Faceted Issue

edited by

Fabrizio Schifano

Norbert Scherbaum

and

Giovanni Martinotti

submission deadline 25 Jul 2025 | 11 articles | Viewed by 37308 | Submission Open

Keywords: addiction spectrum disorders; substance misuse; dual disorders; dopamine; neurotransmitter pathways; reward systems; addiction treatment; reward deficit syndrome; translational anti-craving medications; food addiction; sex addiction; internet gaming disorder; gambling; novel antidiabetics; salience; Novel Psychoactive Substances (NPS); prescription drug misuse; brain– gut axis; microbiome

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

From Visual Perception to Consciousness

edited by

Baingio Pinna

submission deadline 25 Jul 2025 | 6 articles | Viewed by 10515 | Submission Open

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Outcome Measures and Assessment Tools Related to Neurological and Psychological Disorders

edited by

Anna Berardi

and

Giovanni Galeoto

submission deadline 28 Jul 2025 | 1 articles | Viewed by 2357 | Submission Open

Keywords: outcome measures of neurological and psychological disorders; rehabilitation; assessment; reliability; validity; occupational therapy; physiotherapy; speech language therapy; disability

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Cognitive Impairment and Related Complications of Stroke: Prevention, Diagnosis, and Treatment

edited by

Simona Spaccavento

and Pasquale Moretta

submission deadline 30 Jul 2025 | 4 articles | Viewed by 5741 | Submission Open

Keywords: neuropsychological deficits; behavioral symptoms; functional outcomes; cognitive rehabilitation; stroke; post-stroke cognitive impairment

(This special issue belongs to the Section Neurorehabilitation)

The Impact of Stroke on Functional Cognition and Rehabilitation Approaches

edited by Glen Gillen

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2591 | Submission Open

Keywords: cerebrovascular accident; stroke; cognition; activities of daily living; quality of life; assessment; intervention

(This special issue belongs to the Section Neurorehabilitation)

Novel Insights into Neuroinflammation and Brain Disease

edited by Vlad Pădureanu and

Ana-Maria Buga

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1924 | Submission Open

Keywords: oxidative stress; multiple sclerosis; stroke; neuroinflammation; cytokines; genetic polymorphisms; brain diseases

(This special issue belongs to the Section Systems Neuroscience)

Rethinking the Role of Applied Auditory and Music Neuroscience to Neurorehabilitation

edited by Michael H. Thaut and Marija Pranjić

submission deadline 31 Jul 2025 | Viewed by 1813 | Submission Open

Keywords: auditory; music; brain rehabilitation; neuroscience; motor therapy

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Physiological Functions of LRRK2 and Its Pathogenesis

edited by

Dong Hwan Ho

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1384 | Submission Open

Keywords: leucine-rich repeat kinase 2; neuroinflammation; autophagy; ribosomal function; lysosomal degradation; mitochondrial homeostasis; Parkinson’ s disease

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Brain Network Analysis Based on Machine Learning and Neuroimaging

edited by Onur Tanglay

submission deadline 31 Jul 2025 | Viewed by 253 | Submission Open

Keywords: machine learning; neuroimaging; brain network and function; brain connectivity analysis; multimodal data integration; translational applications; neurological disorders

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Burnout, Adjustment Disorder and Post-Traumatic Stress Disorder: Risk Factors, Impact, Preventive Strategies and Treatment Options

edited by

Martina Corsi

and

Rudy Foddis

submission deadline 31 Jul 2025 | Viewed by 197 | Submission Open

Keywords: burnout; AD; PTSD; psychosocial risk; AI; prevention; diagnosis; treatment

(This special issue belongs to the Section Systems Neuroscience)

Prevention, Diagnosis and Treatment for Postoperative Delirium

edited by Ron Oliven

submission deadline 31 Jul 2025 | Viewed by 186 | Submission Open

Keywords: delirium; stressor trigger; dementia; cognitive healthy; Alzheimer's disease; prevention; drugs; early detection; healthcare

(This special issue belongs to the Section Neuropsychiatry)

Human-Centered Robotics Applications in Rehabilitation of Individuals with Neurological Conditions

edited by Giovanni Morone

submission deadline 31 Jul 2025 | Viewed by 140 | Submission Open

Keywords: robotics; neurological disabilities; stroke; gait; rehabilitation

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Brain Magnetic Resonance Imaging in Neurological Disorders: 2nd Edition

edited by

Francesca Benuzzi

and

Claudia Casadio

submission deadline 1 Aug 2025 | 1 articles | Viewed by 1277 | Submission Open

Keywords: neurological disorder; brain; neuroimaging; magnetic resonance imaging; epilepsy; neurodegenerative diseases; brain tumors

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Research Progress on the Pathogenesis, Diagnosis and Treatment of Parkinson Disease

edited by Giulia Carli and Prabesh Kanel

submission deadline 1 Aug 2025 | Viewed by 298 | Submission Open

Keywords: Parkinson’ s disease; Lewy bodies diseases; disease progression; clinical heterogeneity; preclinical and prodromal stages; treatments; comorbidities

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Exploration of Gaming Disorders and Related Mental Health Issues

edited by

Masaru Tateno

and Takanobu Matsuzaki

submission deadline 8 Aug 2025 | Viewed by 154 | Submission Open

Keywords: gaming disorder; internet gaming disorder; hazardous gaming; pathological gaming; internet addiction; problematic internet use; behavioral addiction

(This special issue belongs to the Section Neuropsychology)

Latest Research on the Treatments of Speech and Language Disorders

edited by

Jubin Abutalebi

and Mehdi Bakhtiar

submission deadline 10 Aug 2025 | 1 articles | Viewed by 1747 | Submission Open

Keywords: aphasia; dyslexia; stuttering; TMS; tDCS; artificial intelligence; virtual reality; rehabilitation; neurogenic communication disorders; Non-invasive brain stimulation

(This special issue belongs to the Section Neurolinguistics)

Current Basic and Clinical Approaches in Neurodegenerative Diseases: Diagnostics and Therapeutics

edited by

Genaro G. Ortiz

and Gloria A. Benítez-King

submission deadline 15 Aug 2025 | 3 articles | Viewed by 7565 | Submission Open

Keywords: neurodegenerative diseases; advances; diagnosis; treatment; basic clinical approach; treatment protocols

(This special issue belongs to the Section Neurodegenerative Diseases)

Unraveling the Role of Physical Activity in Brain, Cognition, and Mental Health

edited by

Fiorenzo Moscatelli

, Nicola Mancini and Pompilio Cusano

submission deadline 15 Aug 2025 | 1 articles | Viewed by 821 | Submission Open

Keywords: physical activity; brain health; cognition; mental health; neurogenesis; neuroplasticity; cognitive function; exercise; depression; anxiety

(This special issue belongs to the Section Neuropsychiatry)

The Role and Research Progress of Neuroinflammation in Neurodegenerative Diseases

edited by Flavio Protasio Veras and Bruno Marcel Silva de Melo

submission deadline 15 Aug 2025 | Viewed by 159 | Submission Open

Keywords: neuroinflammation; neurodegenerative diseases; central nervous system; immune system; microglia; astrocytes; inflammatory signaling; molecular pathways; therapeutic targets; brain– immune interactions

(This special issue belongs to the Section Neurodegenerative Diseases)

Neural–Immune Interactions: Understanding the Bidirectional Relationship between the Brain and Immune Cells

edited by

Enrique Becerril-Villanueva

, Alberto Salazar-Juárez and María Dolores Ponce-Regalado

submission deadline 20 Aug 2025 | 2 articles | Viewed by 2253 | Submission Open

Keywords: neuroimmunology; neuroimmunoendocrinology; psychiatric disorders; psycho-oncology; infectious diseases; sickness behavior; neurotransmitters; cytokines; hormones

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Clinical Research on Parkinson’s Disease: Opportunities and Challenges (2nd Edition)

edited by

Santiago Perez-Lloret

, Matilde Otero-Losada and Francisco Capani

submission deadline 20 Aug 2025 | 1 articles | Viewed by 517 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; clinical research; epidemiology; non-motor symptoms; quality of life; technology; observational studies; randomized controlled trials

(This special issue belongs to the Section Neurodegenerative Diseases)

Impact of Environmental Pollution on the Neuro-Vascular Unit

edited by

Jacopo Junio Valerio Branca

and

Alessandra Pacini

submission deadline 20 Aug 2025 | Viewed by 140 | Submission Open

Keywords: neuro-vascular unit (NVU); endothelial cells; astrocytes; pericytes; microglia; neurons; cerebrovascular disorders; neurodegenerative diseases; brain health; environmental pollution

(This special issue belongs to the Section Neuroglia)

The Impact of Various Types of Stressors on the Functioning of Human Body Systems

edited by Marcin Dornowski

submission deadline 22 Aug 2025 | 1 articles | Viewed by 2880 | Submission Open

Keywords: EEG; neurofeedback; stress; stress reaction; physical efficiency; mental efficiency

(This special issue belongs to the Section Neuropsychology)

Multimodal Imaging in Brain Development

edited by Antonio Napolitano

submission deadline 25 Aug 2025 | 4 articles | Viewed by 4466 | Submission Open

Keywords: brain development (BD); brain plasticity; neuroimaging technique; brain connectivity and activity

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Recent Advances and Future Perspectives in Neuro-Oncology and Neuroradiology

edited by Salvatore M. Cardali and

Alfredo Conti

submission deadline 25 Aug 2025 | Viewed by 156 | Submission Open

Keywords: neuro-oncology; neuroradiology; interventional radiology; brain tumor; spine tumor

(This special issue belongs to the Section Neuro-oncology)

Language Perception and Processing

edited by

Ratree Wayland

submission deadline 29 Aug 2025 | 1 articles | Viewed by 705 | Submission Open

Keywords: language; cognitive mechanism; neural mechanism; speech; perception; processing

(This special issue belongs to the Section Neurolinguistics)

Neuroeducation: Bridging Cognitive Science and Classroom Practice

edited by Yuvaraj Rajamanickam

submission deadline 29 Aug 2025 | Viewed by 272 | Submission Open

Keywords: education; neuroscience; learning and memory; neurodevelopmental disorders; emotions; cognitive skills; neuroplasticity; EEG; neuroimaging; school; classroom; educational interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Application of Deep Brain Stimulation in Movement Disorders

edited by

Diane Ruge

and

Carlos Trenado

submission deadline 30 Aug 2025 | Viewed by 313 | Submission Open

Keywords: deep brain stimulation; movement; disorder; brain mechanism; new technology; computational modeling; plasticity; predictive effects

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Perceptual Learning and Cortical Plasticity

edited by Mario Trevino

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1876 | Submission Open

Keywords: perceptual learning; cortical plasticity; synaptic plasticity; neural network models; sensory modalities; neurophysiology; structural plasticity; behavioral neuroscience; rehabilitation neuroscience; experience-dependent plasticity

(This special issue belongs to the Section Behavioral Neuroscience)

Perspectives of Artificial Intelligence (AI) in Aging Neuroscience

edited by

Christos Frantzidis

and

Aristea Ladas

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1666 | Submission Open

Keywords: aging neuroscience; artificial intelligence; brain aging; big data acquisition; chatbots; deep learning; generative AI; robotic assistance; virtual coaches for active aging

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

The Link Between Traumatic Brain Injury (TBI) and Neurodegeneration

edited by

Waldo Cerpa

and Maximiliano Rovegno

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1298 | Submission Open

Keywords: neurodegeneration; acute brain injuries; brain trauma; spreading depression; synaptic plasticity

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Research on Brain Health and Dementia: Prevention and Early Detection of Cognitive Decline and Dementia—3rd Edition

edited by

Takao Yamasaki

submission deadline 31 Aug 2025 | 1 articles | Viewed by 687 | Submission Open

Keywords: brain health; dementia; mild cognitive impairment; Alzheimer's disease; preventive intervention; early detection and diagnosis

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Application of Invasive and Non-Invasive Brain Stimulation Techniques in Neurological Disorders

edited by Vincenzo Levi and

Massimo Marano

submission deadline 31 Aug 2025 | 1 articles | Viewed by 560 | Submission Open

Keywords: deep brain stimulation (DBS); magnetic resonance-guided focused ultrasound (MRgFUS); transcranial magnetic stimulation (TMS); transcranial direct-current stimulation (tDCS); vagus nerve stimulation (VNS); brain– machine interface; brain stimulation; non-invasive brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Beyond the Brain: Merging Embodied Mind and AI in the Clinical Neuroscience of Psychotherapy

edited by

Raffaele Sperandeo

and

Valeria Cioffi

submission deadline 31 Aug 2025 | Viewed by 452 | Submission Open

Keywords: holistic approach; psychotherapy; neuroscience; complex systems; self-organization; interdisciplinary research; artificial intelligence; embodied mind

(This special issue belongs to the Section Neuropsychology)

Neuromorphic Artificial Intelligence and Its Applications: Retrospective and Prospective

edited by Vassilis Cutsuridis

submission deadline 31 Aug 2025 | Viewed by 388 | Submission Open

Keywords: neuromorphic artificial intelligence; deep learning; sensory recognition; cognitive function; cognitive robotics; neuroimaging

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

From Brain Circuits to Behavior: A Neuroendocrine Perspective

edited by María Elena Hernández-Aguilar, Fausto Rojas-Durán,

Deissy Herrera-Covarrubias

and

María Rebeca Toledo-Cárdenas

submission deadline 31 Aug 2025 | Viewed by 128 | Submission Open

Keywords: hormones; nervous system; molecular biology; neuroplasticity; stress; cancer; biomarkers; circadian rhythms

(This special issue belongs to the Section Behavioral Neuroscience)

Cellular and Molecular Study of Neurodevelopmental and Neurological Disorders

edited by

Kazuhito Toyooka

submission deadline 31 Aug 2025 | Viewed by 72 | Submission Open

Keywords: Autism spectrum disorder (ASD); Attention deficit hyperactivity disorder (ADHD); Schizophrenia; Bipolar disorder; Intellectual disability (ID); Cognitive disorders; Alzheimer’ s disease (AD); Parkinson’ s disease (PD); Traumatic brain injury (TBI)

New Approaches in the Exploration of Parkinson’s Disease

edited by

and

submission deadline 10 Sep 2025 | 9 articles | Viewed by 15266 | Submission Open

Keywords: Parkinson’ s disease; neurodegenerative disorders; nonmotor symptoms; quality of life; cognition; olfactory deficits

(This special issue belongs to the Section Neurodegenerative Diseases)

The Rehabilitation of Neurologic Disorders

edited by

Francisco Nieto-Escamez

submission deadline 10 Sep 2025 | 4 articles | Viewed by 6654 | Submission Open

Keywords: neurologic rehabilitation; neuroplasticity; stroke recovery; traumatic brain injury; neurodegenerative diseases; robotic therapy; virtual reality rehabilitation; cognitive rehabilitation; motor function recovery; advanced therapies

(This special issue belongs to the Section Neurorehabilitation)

Advances in Global Sleep and Circadian Health

edited by

Lourdes DelRosso

submission deadline 15 Sep 2025 | 2 articles | Viewed by 4160 | Submission Open

Keywords: global sleep health; sleep medicine; sleep disorders; sleep disparities; sleep diagnostics; circadian effects on sleep health; shift work disorder and productivity; chronic diseases and sleep; sleep and mental health; sleep health equity; representation in sleep research (age; gender); primary care and sleep; social determinants of sleep health; cross-cultural sleep health

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Studies in Human Performance and Experience: Neuroscience and Functional Brain Imaging: 2nd Edition

edited by

Kurtulus Izzetoglu

submission deadline 15 Sep 2025 | 2 articles | Viewed by 3352 | Submission Open

Keywords: cognitive load; mental workload; functional brain imaging; fNIRS; fMRI; EEG; eye tracking; learning; training; human-autonomy teaming

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Locus Coeruleus Function and Vulnerability in Neurodegenerative Conditions: Evidence from Animal Model and Human Imaging Studies

edited by

Oxana Eschenko

and Dorothea Hämmerer

submission deadline 15 Sep 2025 | Viewed by 355 | Submission Open

Keywords: noradrenaline; locus coeruleus; neuromodulation; magnetic resonance imaging; neurodegeneration; psychiatric disorders; sleep; brainstem

(This special issue belongs to the Section Systems Neuroscience)

Traumatic Stress and Dissociative Disorder

edited by Federica Visco-Comandini

submission deadline 19 Sep 2025 | 2 articles | Viewed by 6442 | Submission Open

Keywords: PTSD; dissociation; C-PTSD; trauma exposure; interpersonal violence; abuse; relational trauma; childhood abuse

(This special issue belongs to the Section Neuropsychiatry)

Behavioural, Emotional and Cognitive Processes Linked to Healthy Sleep and Insomnia

edited by Chiara Baglioni and Debora Meneo

submission deadline 20 Sep 2025 | Viewed by 148 | Submission Open

Keywords: sleep health; insomnia; emotional processes; pre-sleep behaviours; cognitive processes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Unraveling Autism: Neurobiological Mechanisms and Emerging Therapeutic Advances

edited by Antonio Nicotera and

Gabriella Di Rosa

submission deadline 25 Sep 2025 | 2 articles | Viewed by 3876 | Submission Open

Keywords: autism; neurobiology; autistic spectrum disorder; neurodevelopment; genetic

(This special issue belongs to the Section Developmental Neuroscience)

Understanding the Functioning of Brain Networks in Health and Disease

edited by

Moses O. Sokunbi

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1599 | Submission Open

Keywords: brain networks; cognitive dysfunction; diffusion tensor imaging (DTI); electroencephalography (EEG); functional connectivity; functional magnetic resonance imaging (fMRI); magnetoencephalography (MEG); neurological disorders; neuroplasticity; psychiatric disorders; artificial intelligence; deep learning; neural networks; signal complexity

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Brain Development—Shedding Light on Opioid Exposure and Health Disparities

edited by

Adam Abba-Aji

submission deadline 25 Sep 2025 | 1 articles | Viewed by 443 | Submission Open

Keywords: opioids; brain development; cognition; quality of life

(This special issue belongs to the Section Developmental Neuroscience)

Molecular Insights in Neurodegeneration

edited by

Oscar Arias-Carrión

submission deadline 25 Sep 2025 | 1 articles | Viewed by 294 | Submission Open

Keywords: neurodegeneration; molecular mechanisms; protein aggregation; neuroinflammation; oxidative stress; mitochondrial dysfunction; Alzheimer& rsquo; s disease; Parkinson& rsquo; s disease; biomarkers; therapeutic targets

(This special issue belongs to the Section Neurodegenerative Diseases)

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