The Role and Research Progress of Neuroinflammation in Neurodegenerative Diseases
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: 15 August 2025 | Viewed by 117
Special Issue Editors
Interests: neuroinflammation; neuropharmacology; infectious diseases; neurotropic viruses
Special Issues, Collections and Topics in MDPI journals
2. Center for Research in Inflammatory Diseases, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil
Interests: neuroimmunology; neuroinflammation; gut–brain axis; multiple sclerosis
Special Issue Information
Dear Colleagues,
Neuroinflammation has emerged as a key area of interest for understanding the mechanisms behind the onset, development, and persistence of numerous neurological disorders, especially in the case of neurodegenerative diseases. This inflammation can originate from local processes within the central nervous system (CNS) or stem from inflammatory signals circulating from the periphery, emphasizing the complex bidirectional interactions between the immune system and the brain. Cellular signaling is central to the regulation of neuroinflammation, with immune cells such as microglia and astrocytes playing a critical role in activating inflammatory responses. The aim of this Special Issue, therefore, is to present the latest research exploring the role of neuroinflammation in the development and progression of neurodegenerative diseases. We invite contributions that investigate the mechanisms by which neuroinflammatory signaling affects diseases. We welcome both clinical and experimental studies that aim to uncover the molecular pathways underlying neuroinflammation and to identify potential therapeutic targets to modulate the immune response in the brain.
Dr. Flavio Protasio Veras
Guest Editor
Dr. Bruno Marcel Silva de Melo
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- neuroinflammation
- neurodegenerative diseases
- central nervous system
- immune system
- microglia
- astrocytes
- inflammatory signaling
- molecular pathways
- therapeutic targets
- brain–immune interactions
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