Clinical Research on Parkinson’s Disease: Opportunities and Challenges (2nd Edition)
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 216
Special Issue Editors
2. Department of Physiology, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina
Interests: Parkinson’s disease; neuropsychological disorders; disease-modifying therapies; clinical research; epidemiology; non-motor symptoms; quality of life; technology
Special Issues, Collections and Topics in MDPI journals
Interests: neurodegeneration; metabolic syndrome; diabetes; oxidative stress; inflammation
Special Issues, Collections and Topics in MDPI journals
2. Institute of Biomedical Sciences, Faculty of Health Sciences, Autonomous University of Chile, Santiago 7500912, Chile
Interests: neurodegeneration-neuroprotection; cell biology-synapses; 3D reconstructions; electron tomography
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There are no adequate animal or cellular models of the chronic, insidious development of Parkinson’s Disease (PD) or most non-motor symptoms that affect patients. Therefore, clinical research is essential to better understanding the genesis, progression, and treatment of PD. Furthermore, genetic influences can only be studied using clinical studies. Quality of life is one of the most important aspects for patients; thus, more research about its determinants using observational studies is required. Finally, new treatments for non-motor features and improved therapies for motor symptoms are urgently needed.
This Special Issue includes the most recent and cutting-edge research on clinical aspects of PD, including diagnosis, the assessment of motor and non-motor symptoms, biochemical testing, the evaluation of prognostic factors, the development of machine learning/artificial intelligence algorithms, and the evaluation of treatment efficacy and safety. All types of papers, including original articles, brief reports, opinion articles, systematic reviews, and meta-analyses, are welcome. Authors from all around the world are encouraged to submit high-quality research articles to this Special Issue.
Dr. Santiago Perez-Lloret
Dr. Matilde Otero-Losada
Dr. Francisco Capani
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Parkinson’s disease
- disease-modifying therapies
- clinical research
- epidemiology
- non-motor symptoms
- quality of life
- technology
- observational studies
- randomized controlled trials
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