Novel Insights into Pediatric Dystonia and Childhood-Onset Movement
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Sensory and Motor Neuroscience".
Deadline for manuscript submissions: 21 July 2025 | Viewed by 322
Special Issue Editor
Interests: child neurology; pediatric movement disorders; computational neuroscience; brain and cognitive sciences; biomedical engineering
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The standard clinical model of basal ganglia function and its role in movement disorders has been a useful target for proof and disproof, inspiring much research over the past 40 years. Whether this model applies to childhood movement disorders is unknown. This Special Issue will describe childhood movement disorders and models of basal ganglia function and disease that may facilitate our understanding and treatment of these disorders.
The complexity of basal ganglia function and disease during development requires theories and models that help us to explain the relation between childhood disease processes, growth, development, and clinical outcomes. As has often been quoted, "all models are false; some models are useful", and models of deep brain nuclei are no exception. In this issue, we do not aim to establish a definitive model or even to definitively reject existing models. Our goal is to examine clinical phenomena and their origins that could lead to models of developmental movement disorders and to propose a set of possibilities that will broaden our thinking and inspire both clinical and basic science research toward improved outcomes. To this end, we seek innovative clinical observations, and theories that are supported by evidence and experience and that have (1) utility to guide the treatment of disease, (2) validity with reference to experimental observations, and (3) consistency. The goal is to establish a Special Issue that inspires, provokes, fascinates, and drives us to think as deeply as possible about some of the most complex and least understood components of the developing human motor system.
We are pleased to invite you to contribute a manuscript of any length, although 8–10 manuscript pages would be ideal. While we welcome in silico, in vitro, and non-human results, we strongly encourage you to relate those results to the origins and potential treatments of pediatric movement disorders. When appropriate, we may ask you to include references to each other’s manuscripts so that readers can understand the similarities, differences, and linkages between the ideas to be presented.
Prof. Dr. Terence Sanger
Guest Editor
Manuscript Submission Information
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Keywords
- basal ganglia function
- movement disorders
- theories and models
- clinical research
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