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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 84 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Inflammation, Stress, and Comorbidity in Psychiatry: Mechanisms and Therapeutic Implications

edited by Heline Mirzakhanian

submission deadline 20 Mar 2026 | Viewed by 83 | Submission Open

Keywords: immune biomarkers in psychiatry; neuroinflammation; precision neuropsychiatry; risk mechanisms; comorbidity models; HPA axis dysregulation; anti-inflammatory treatments; psychiatric and physical comorbidity; cytokine signaling; microglial activation

(This special issue belongs to the Section Neuropsychiatry)

Neural Correlates of Cognitive Workload and Learning: Portable Brain Monitoring During Skill Acquisition and Real-World Task Performance

edited by Adrian Curtin, Sebastien Scannella,

Hasan Ayaz

and

Candida Barreto

submission deadline 25 Mar 2026 | 1 articles | Viewed by 446 | Submission Open

Keywords: portable neuroimaging; wearable brain sensing; skill acquisition; expertise development; motor learning; cognitive workload; fNIRS/EEG applications; neural efficiency; closed-loop training; neurostimulation (tDCS/rTMS/FUS)

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Balance: Multisensory Integration and Rehabilitation Approaches

edited by

Min-wook Kim

submission deadline 25 Mar 2026 | Viewed by 168 | Submission Open

Keywords: multisensory integration; balance and gait disorders; vestibular; visual; and somatosensory assessment; postural control; sensorimotor dysfunction; neurodegenerative diseases (e.g.; Parkinson’ s; PSP); stroke and brain injury; motor rehabilitation; virtual and augmented reality; neuroplasticity; fall risk and prevention; wearable technology and kinematic analysis

(This special issue belongs to the Section Neurodegenerative Diseases)

Language Perception and Processing

edited by

Ratree Wayland

submission deadline 27 Mar 2026 | 6 articles | Viewed by 6502 | Submission Open

Keywords: language; cognitive mechanism; neural mechanism; speech; perception; processing

(This special issue belongs to the Section Neurolinguistics)

Neuropsychological Exploration of Spatial Cognition and Navigation

edited by

Jose Manuel Cimadevilla

Laura Piccardi

Raffaella Nori

Maria Kozhevnikov

and Sean Commins

submission deadline 27 Mar 2026 | 3 articles | Viewed by 3811 | Submission Open

Keywords: spatial memory; neuropsychological; spatial navigation; cognitive disorder; Alzheimer’ s disease; spatial cognition; dementia; brain Function

(This special issue belongs to the Section Neuropsychology)

Palliative Care for Patients with Severe Neurological Impairment

edited by

Giovanna Artioli

and

Federica Dellafiore

submission deadline 30 Mar 2026 | 4 articles | Viewed by 5057 | Submission Open

Keywords: severe neurological impairment; neurological chronic disease; palliative care; early palliative care; nursing competencies; advance care planning; caregiver support; mental Illness of Healthcare professionals; non pharmacological and complementary treatment; bio-psyco-social and existential needs of patient and caregiver

(This special issue belongs to the Section Neurorehabilitation)

Editorial Board Collection Series: Innovative Research in Molecular and Cellular Neuroscience for Regulation of Cell Death Mechanisms for Functional Neuroprotection

edited by

Swapan K. Ray

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3964 | Submission Open

Keywords: apoptosis; autophagy; artificial intelligence; CRISPR; demyelination; ferroptosis; inflammasomes; microRNAs; necrosis; neuroprotection; organoids; PANoptosis; animal and cellular models of neurological diseases and injuries; proteases

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Advances in LRRK2 and Other Pathological Mechanisms of Parkinson's Disease

edited by

Dong Hwan Ho

submission deadline 31 Mar 2026 | 1 articles | Viewed by 3469 | Submission Open

Keywords: Parkinson's disease; leucine-rich repeat kinase 2; dopaminergic neuronal death; neurodegenerative disease; neuroinflammation; neuroprotection

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Burnout, Adjustment Disorder and Post-Traumatic Stress Disorder: Risk Factors, Impact, Preventive Strategies and Treatment Options

edited by

Martina Corsi

and

Rudy Foddis

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2293 | Submission Open

Keywords: burnout; AD; PTSD; psychosocial risk; AI; prevention; diagnosis; treatment

(This special issue belongs to the Section Systems Neuroscience)

Research Progress on the Pathogenesis, Diagnosis and Treatment of Parkinson Disease

edited by Giulia Carli and Prabesh Kanel

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2164 | Submission Open

Keywords: Parkinson’ s disease; Lewy bodies diseases; disease progression; clinical heterogeneity; preclinical and prodromal stages; treatments; comorbidities

(This special issue belongs to the Section Neurodegenerative Diseases)

Dementia and Cognitive Decline in Aging

edited by

Yvonne Leung

submission deadline 31 Mar 2026 | 3 articles | Viewed by 1152 | Submission Open

Keywords: dementia; cognitive impairment; Alzheimer’ s disease; mild cognitive impairment (MCI); neurodegeneration; cognitive aging; biomarkers; cognitive resilience; cognitive reserve

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Plasticity of Sensory Cortices: From Basic to Clinical Research

edited by Stephanie Clarke and Sonia Crottaz-Herbette

submission deadline 31 Mar 2026 | 1 articles | Viewed by 575 | Submission Open

Keywords: tonotopy; retinotopy; somatotopy; vestibular; olfactory; gustatory; training-induced plasticity; postlesional plasticity; cochlear implant; prostheses

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Emerging Trends and Perspectives in the Neuroscience of Pain

edited by Martina Rekatsina and

Panagiotis Zis

submission deadline 31 Mar 2026 | Viewed by 148 | Submission Open

Keywords: neuroscience of pain; neuroimaging techniques; neuromodulation therapies; pain mechanisms; chronic pain

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Shaping the Brain in Sleep: Neurodevelopmental Mechanisms Across the Lifespan

edited by Sally Staton, Jasneek Chawla and Kartik Iyer

submission deadline 31 Mar 2026 | Viewed by 128 | Submission Open

Keywords: sleep; brain development; neurodevelopment; sensitive periods; napping; genetic and environmental influences; early childhood; adolescents; adulthood; lifespan development

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Stress and Trauma Revisited: Oxytocin, Sociostasis, and Hormesis—Missing Pieces of an Evolving Puzzle

edited by C. Sue Carter, Marcy Kingsbury and Hans Nazarloo

submission deadline 31 Mar 2026 | Viewed by 113 | Submission Open

Keywords: oxytocin; vasopressin; stress; sociostasis; hormesis

(This special issue belongs to the Section Systems Neuroscience)

Neuroimmune Crosstalk in Neurological Disorders: Mechanistic Insights to Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 31 Mar 2026 | Viewed by 113 | Submission Open

Keywords: neuroinflammation; neuroimmune system; glial cell dynamics; immune cell trafficking; cyto-kine signaling; neurological disorders; immune modulation

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Psychiatry and Addiction: A Multi-Faceted Issue—2nd Edition

edited by

Fabrizio Schifano

Norbert Scherbaum

and

Giovanni Martinotti

submission deadline 31 Mar 2026 | Viewed by 95 | Submission Open

Keywords: addiction spectrum disorders; substance misuse; dual disorders; alcohol misuse; prescription drug misuse; dopamine; neurotransmitter pathways; reward systems; addiction treatment; reward deficit syndrome; translational anti-craving medications; food addiction; sex addiction; internet gaming disorder; gambling; novel antidiabetics; salience; novel psychoactive substances (NPSs); prescription drug misuse; brain– gut axis; microbiome

(This special issue belongs to the Section Behavioral Neuroscience)

Advances in Immune-Mediated Disorders of the Nervous System in Childhood

edited by Martino Ruggieri and

Andrea Domenico Praticò

submission deadline 10 Apr 2026 | Viewed by 214 | Submission Open

Keywords: autoimmune encephalitis; pediatric neuroinflammation; immune-mediated CNS disorders; childhood multiple sclerosis; MOG antibody disease; neuroimmunology; immunotherapy in children; neuromyelitis optica

(This special issue belongs to the Section Developmental Neuroscience)

New Perspectives on Language Processing in Aging

edited by Andrea Marini

submission deadline 15 Apr 2026 | 1 articles | Viewed by 1107 | Submission Open

Keywords: aging; language; cognition; phonology; lexical skills; grammatical skills; pragmatics; discourse; neuropsychology of language

(This special issue belongs to the Section Neurolinguistics)

Gait and Balance Analysis in Parkinson’s Disease

edited by Timothy Adam Thrasher

submission deadline 15 Apr 2026 | Viewed by 104 | Submission Open

Keywords: Parkinson’ s disease; gait; postural instability; falls; rehabilitation

(This special issue belongs to the Section Neurodegenerative Diseases)

Clinical Translation in Disorders of Consciousness: New Pathways and Challenges

edited by

Caroline Schnakers

and

Katherine O'Brien

submission deadline 15 Apr 2026 | Viewed by 69 | Submission Open

Keywords: disorders of consciousness; brain injury; consciousness; coma

(This special issue belongs to the Section Systems Neuroscience)

Neural–Immune Interactions: Understanding the Bidirectional Relationship between the Brain and Immune Cells

edited by

Enrique Becerril-Villanueva

, Alberto Salazar-Juárez and María Dolores Ponce-Regalado

submission deadline 16 Apr 2026 | 2 articles | Viewed by 3286 | Submission Open

Keywords: neuroimmunology; neuroimmunoendocrinology; psychiatric disorders; psycho-oncology; infectious diseases; sickness behavior; neurotransmitters; cytokines; hormones

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Neuropsychological Impact and Quality of Life in Chronic Illness

edited by

Nicoletta Ciccarelli

and

Elisa Pini

submission deadline 20 Apr 2026 | 3 articles | Viewed by 4208 | Submission Open

Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures

(This special issue belongs to the Section Neuropsychology)

Cerebral Amyloid Angiopathy: Advances in the Field

edited by Ulf Jensen-Kondering and

Benedetta Storti

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2364 | Submission Open

Keywords: cerebral amyloid angiopathy; cerebral small vessel disease; cerebral hemorrhage; vascular dementia; stroke; amyloid; CAA-ri; iatrogenic CAA

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Brain Mechanisms of Hot and Cold Executive Function in Healthy and Clinical Populations

edited by

Sandra Carvalho

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1976 | Submission Open

Keywords: executive function; hot executive function; cold executive function; cognitive control; emotion; cognition interaction; emotion regulation; transdiagnostic mechanisms

(This special issue belongs to the Section Behavioral Neuroscience)

Brain Plasticity and Motor Control—3rd Edition

edited by

Bernadette Murphy

submission deadline 20 Apr 2026 | Viewed by 130 | Submission Open

Keywords: brain; neuroplasticity; motor control; sensorimotor integration; sensory input

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Addressing ADHD in Children: Contemporary Treatment Strategies

edited by Richard Gallagher

submission deadline 20 Apr 2026 | Viewed by 88 | Submission Open

Keywords: ADHD (attention deficit hyperactivity disorders); children; adolescent; executive function deficits and treatment; functional impairments; psychosocial interventions; brain activity-targeted treatments

(This special issue belongs to the Section Developmental Neuroscience)

Neuroregulatory Factors in Neurodevelopmental Plasticity: From Stem Cell Differentiation to Neural Circuit Maturation

edited by

Anayansi Molina-Hernández

submission deadline 20 Apr 2026 | Viewed by 56 | Submission Open

Keywords: neurodevelopmental plasticity; neural stem cells; differentiation; neural circuit maturation; epigenetic regulation; synaptic plasticity; neurodevelopmental disorders; translational neuroscience

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Beyond the Brain: Merging Embodied Mind and AI in the Clinical Neuroscience of Psychotherapy

edited by

Raffaele Sperandeo

and

Valeria Cioffi

submission deadline 24 Apr 2026 | 3 articles | Viewed by 6730 | Submission Open

Keywords: holistic approach; psychotherapy; neuroscience; complex systems; self-organization; interdisciplinary research; artificial intelligence; embodied mind

(This special issue belongs to the Section Neuropsychology)

Molecular and Cellular Research in Neurodegenerative Diseases

edited by

Kallirhoe Kalinderi

submission deadline 25 Apr 2026 | 2 articles | Viewed by 4208 | Submission Open

Keywords: neurodegenerative diseases; Parkinson’ s disease; Alzheimer’ s disease; Huntington’ s disease; amyotrophic lateral sclerosis; gene; mechanism; molecular; cellular; pathophysiology

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Global Sleep and Circadian Health

edited by

Lourdes DelRosso

submission deadline 30 Apr 2026 | 3 articles | Viewed by 19617 | Submission Open

Keywords: global sleep health; sleep medicine; sleep disorders; sleep disparities; sleep diagnostics; circadian effects on sleep health; shift work disorder and productivity; chronic diseases and sleep; sleep and mental health; sleep health equity; representation in sleep research (age; gender); primary care and sleep; social determinants of sleep health; cross-cultural sleep health

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Psychedelic and Interventional Psychiatry

edited by

Mark S. Gold

submission deadline 30 Apr 2026 | 4 articles | Viewed by 11038 | Submission Open

Keywords: psychedelics; ketamine; interventional psychiatry; psychedelic medicine; LSD; DMT; psilocybin; MDMA; depression; anxiety; end of life; palliative medicine; treatment-resistant depression; OCD; anorexia nervosa; eating disorders; nitrous oxide; TMS; DBS; alcohol use disorders; substance use disorders; trauma; post-traumatic stress disorders; PTSD; ketamine and other psychedelic use disorders

(This special issue belongs to the Section Neuropsychiatry)

Advances in Face Perception and How Disorders Affect Face Perception

edited by Karen Lander, Rachel Bennetts and Natalie Butcher

submission deadline 30 Apr 2026 | 5 articles | Viewed by 5020 | Submission Open

Keywords: face perception; face recognition; prosopagnosia; neurodevelopmental disorders; individual differences; clinical disorders

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Review in Neuropsychology: Advances and Future Directions

edited by

Sara Palermo

Pierluigi Zoccolotti

and

Laura Piccardi

submission deadline 30 Apr 2026 | Viewed by 775 | Submission Open

Keywords: aphasia; attentional disorders; hemineglect; amnesia; apraxia; neurodevelopmental disorders; neuropsychological approach; neuroscience

(This special issue belongs to the Section Neuropsychology)

Innovations in Pediatric Functional Neurosurgery

edited by Samuel Tomlinson and Benjamin C. Kennedy

submission deadline 30 Apr 2026 | Viewed by 197 | Submission Open

Keywords: pediatric neurosurgery; functional neurosurgery; epilepsy; movement disorders; spasticity; dystonia; surgical innovation; minimally invasive surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

New Insights into Mental Health Research for Neurological and Psychiatric Disorders

edited by

Francesco Corallo

and

Lilla Bonanno

submission deadline 30 Apr 2026 | 1 articles | Viewed by 189 | Submission Open

Keywords: neuropsychiatric disorders; mental health; neurological conditions; comorbidity; integrated care; interventions; digital health; neuroimaging; artificial intelligence; personalized medicine

(This special issue belongs to the Section Neuropsychiatry)

Neuroimaging of Cerebral Small Vessel Disease

edited by Sheelakumari Raghavan

submission deadline 30 Apr 2026 | Viewed by 149 | Submission Open

Keywords: Small Vessel Disease; neuroimaging; MRI; cognitive impairment; imaging biomarkers

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Intracranial Aneurysms

edited by Mario Zuccarello and Sudhakar Vadivelu

submission deadline 30 Apr 2026 | Viewed by 143 | Submission Open

Keywords: intracranial aneurysms; natural history; improved diagnosis; minimally invasive treatment; device development; molecular mechanisms; emerging drug therapies; artificial intelligence; prevention strategies; public education

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Advances in Parkinson's Disease and Other Movement Disorders

edited by Quincy J. Almeida

submission deadline 30 Apr 2026 | Viewed by 94 | Submission Open

Keywords: Parkinson’ s disease; movement disorders; artificial intelligence; machine learning; gait; relevant mechanisms; freezing; tremor

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Perspectives on Brain Tumor: From Basic Studies to Clinical Treatment and Rehabilitation

edited by Luca Zigiotto and Silvio Sarubbo

submission deadline 30 Apr 2026 | Viewed by 91 | Submission Open

Keywords: brain tumor surgery; awake surgery; cognitive impairments and rehabilitation; neuropsychology; brain functional networks; structural and functional connectivity; white matter fibers; quality of life; high-grade gliomas; low-grade gliomas

(This special issue belongs to the Section Neuro-oncology)

New Approaches to Prevent Neuropsychiatric Disorders Through the Control of Neuroinflammation

edited by Yoshikaszu Matsuda

submission deadline 30 Apr 2026 | Viewed by 80 | Submission Open

Keywords: neuroinflammation; Alzheimer's disease; microglia; neuroprotective effect; neuropsychiatric disorders; smoldering inflammation

(This special issue belongs to the Section Neurodegenerative Diseases)

Cognitive Training and Physical Exercise: Evidence-Based Strategies for Healthy Aging

edited by

Takao Yamasaki

submission deadline 30 Apr 2026 | Viewed by 78 | Submission Open

Keywords: cognitive training; physical exercise; healthy aging; mild cognitive impairment; dementia; cognitive decline; neuroplasticity; brain health; executive function; memory

(This special issue belongs to the Section Systems Neuroscience)

Neuroscience: Advances in Nanotechnologies

edited by Mohammednadim Sardoiwala

submission deadline 30 Apr 2026 | Viewed by 70 | Submission Open

Keywords: nanomedicine; neurotherapeutics; neuro-oncology; nano-bioimaging; diagnosis; neural regeneration

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Progress in Prosopagnosia Research

edited by

Andrea Albonico

submission deadline 30 Apr 2026 | Viewed by 62 | Submission Open

Keywords: prosopagnosia; face recognition; treatment; diagnosis; development; face blindness

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

The Neural Processes Underlying Parkinson’s Disease and Related Synucleinopathies

edited by Danielle E. Mor

submission deadline 5 May 2026 | Viewed by 299 | Submission Open

Keywords: α -synuclein; synucleinopathies; Parkinson’ s disease; dementia with Lewy bodies; multiple system atrophy; neurodegeneration; protein aggregation

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Dopamine and Cognition

edited by

Luca Aquili

submission deadline 10 May 2026 | 1 articles | Viewed by 3557 | Submission Open

Keywords: dopaminergic system; cognitive neuroscience; reinforcement learning; neuropsychopharmacology; motivation and decision making

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Accessing Treatment and Rehabilitation for Underserved Survivors of Brain Injury

edited by Eve M. Valera

submission deadline 10 May 2026 | Viewed by 162 | Submission Open

Keywords: TBI; brain injury; partner violence; incarcerated; homeless; rehabilitation; strangulation; criminal justice system; barriers

Editorial Board Collection Series: Advances in Neuro-Oncology

edited by

Terry Lichtor

submission deadline 15 May 2026 | 9 articles | Viewed by 18053 | Submission Open

Keywords: brain tumors; gliomas; cytokine gene vaccine therapy; immunotherapy; angiogenesis; checkpoint inhibitors; dendritic cell therapy

(This special issue belongs to the Section Neuro-oncology)

Rethinking Neurodevelopmental Disorders: Beyond One-Size-Fits-All

edited by Salman Zubedat

submission deadline 15 May 2026 | 1 articles | Viewed by 2997 | Submission Open

Keywords: ADHD; autism; intellectual disability; communication disorders

(This special issue belongs to the Section Developmental Neuroscience)

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