Cerebral Amyloid Angiopathy: Advances in the Field
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurosurgery and Neuroanatomy".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 407
Special Issue Editors
Interests: neuroradiology; stroke; cerebral amyloid angiopathy; cerebral small vessel disease; cerebral hemorrhage; biomarkers; MRI; CT
Special Issue Information
Dear Colleagues,
The Background and History of This Topic:
Cerebral amyloid angiopathy (CAA) is a frequent condition in the elderly, recognized as the leading cause of lobar haemorrhages, and, over time, the spectrum of clinical manifestations associated with CAA has expanded beyond haemorrhagic events to include cognitive decline, transient focal neurological episodes (TFNEs), microinfarcts, and white matter damage. Additionally, asymptomatic presentations, inflammatory forms (CAA-related inflammation—CAA-ri), hereditary variants, and iatrogenic CAA have been described, highlighting the complexity and heterogeneity of the disease. The close relationship between CAA and Alzheimer’s disease has also gained increasing attention, given the shared pathological substrate of amyloid deposition.
The Aim and Scope of this Special Issue:
This Special Issue aims to comprehensively explore CAA in all its forms, including its clinical, radiological, and pathological aspects. Special emphasis will be placed on diagnostic parameters — both established and emerging — while insights into the broader context of diseases overlapping with CAA are also welcome. Contributions that advance the understanding of pathophysiology, therapeutic strategies, and clinical outcomes are highly encouraged.
Cutting-Edge Research:
Recent research has focused on expanding diagnostic tools beyond traditional imaging, with CSF, blood biomarkers, and PET imaging gaining prominence. The recognition of inflammatory and hereditary subtypes, as well as iatrogenic forms, represents a cutting-edge development, highlighting the necessity for refined diagnostic criteria and targeted therapeutic approaches.
What Kind of Papers are Solicited:
We seek to submission of original research articles, comprehensive reviews, detailed case reports, and commentaries that contribute to the knowledge of CAA. Contributions can address diagnostic innovations, pathophysiological mechanisms, therapeutic interventions, disease progression, and outcome predictors. Studies exploring experimental biomarkers or novel imaging techniques are particularly welcome.
Dr. Ulf Jensen-Kondering
Dr. Benedetta Storti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cerebral amyloid angiopathy
- cerebral small vessel disease
- cerebral hemorrhage
- vascular dementia
- stroke
- amyloid
- CAA-ri
- iatrogenic CAA
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
