Neuroimmune Crosstalk in Neurological Disorders: Mechanistic Insights to Therapeutic Interventions
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 7
Special Issue Editor
Interests: neuropharmacology and toxicology; molecular neuroscience and neural circuit development; brain insulin resistance and neurodegeneration; preclinical models of Alzheimer’s disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The brain has long been considered as an organ that is independent from the immune system, but several studies from last few decades have provided insights into a complex and vital interplay between the central nervous system and the immune system. In addition, cytokine disparity, microglial activation, and immune dysregulation have recently been noted as commonly occurring pathological hallmarks across multiple brain disorders. In this regard, neuroimmune crosstalk has been found to play a critical role in the pathophysiological aspects of numerous neurodegenerative, neurodevelopmental, and neuropsychiatric disorders, including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, depression, schizophrenia, epilepsy, and autism.
This Special Issue focuses on the mechanisms of neuroimmune interaction and underscores the breakthrough advances made in targeting these pathways as a form of therapeutic intervention. We welcome the submission of original research articles, reviews, and short communications that present novel insights into immune cascades in the brain and their implications for neuronal degeneration, function, therapy, and repair.
Dr. Ansab Akhtar
Guest Editor
Manuscript Submission Information
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Keywords
- neuroinflammation
- neuroimmune system
- glial cell dynamics
- immune cell trafficking
- cyto-kine signaling
- neurological disorders
- immune modulation
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