Special Issues

Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Microbiome in Neurological Disorders
edited by
submission deadline 20 Dec 2025 | Viewed by 410 | Submission Open
Keywords: microbiome; brain– microbiome axis; brain– gut axis; neurological disorders; neurodegenerative; neurodevelopmental; neuroinflammatory; human microbiome
Anti-Aggregation Therapies Targeting Amyloid-Beta, Tau and Alpha-Synuclein and Other Proteins Associated with Neurodegenerative Disorders
edited by
submission deadline 20 Dec 2025 | Viewed by 264 | Submission Open
Keywords: amyloid-beta (Aβ ) aggregation; Tau aggregation; alpha-synuclein (α -Syn) aggregation; TAR DNA-binding protein 43 (TDP-43) aggregation; superoxide dismutase (SOD1) aggregation; Huntingtin (HTT) aggregation; prion protein (PrPá¶œ); protein aggregation; anti-protein aggregating agents; proteinopathies; neurodegeneration
(This special issue belongs to the Section Neurodegenerative Diseases)
Falls: Developing, Understanding, and Communicating Effective Interventions
edited by and
submission deadline 20 Dec 2025 | Viewed by 166 | Submission Open
Keywords: gait; posture; fall prevention; balance disorders; rehabilitation; assistive technology; neurological disorders; wearable devices; intervention strategies; clinical practice; intervention communication
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Artificial Intelligence in Neurological Disorders submission deadline 24 Dec 2025 | 1 articles | Viewed by 1096 | Submission Open
Keywords: artificial intelligence; neurological disorders; machine learning; deep learning; neuroimaging; Alzheimer’ s disease; Parkinson’ s disease; predictive analytics; personalized medicine; ethical AI
(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
Risk Factors for Tinnitus and Tinnitus-Related Disease
edited by and Alberto Eibenstein
submission deadline 25 Dec 2025 | 1 articles | Viewed by 3522 | Submission Open
Keywords: tinnitus; anxiety; depression; stress; migraine; hearing loss; insomnia; biomarkers; noise; ototoxicity
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Brain Stimulation for Psychiatric Disorders: Emerging Evidence and New Perspectives—2nd Edition submission deadline 30 Dec 2025 | 9 articles | Viewed by 27237 | Submission Open
Keywords: repetitive transcranial magnetic stimulation (rTMS) and Theta burst stimulation (TBS); transcranial electrical stimulation (tES) (transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); transcranial random noise stimulation (tRNS)); magnetic seizure therapy (MST); depression; bipolar disorder; and other mood disorders; schizophrenia and psychosis; obsessive– compulsive disorder and anxiety disorders; substance use disorders; neurodevelopmental disorders (ADHD; autism); neuroimaging; neurophysiology; cognition
(This special issue belongs to the Section Neuropsychiatry)
Cellular and Molecular Mechanisms Regulating Neuronal Function, Homeostasis, and Disease submission deadline 31 Dec 2025 | 5 articles | Viewed by 8792 | Submission Open
Keywords: molecular mechanisms; cellular mechanisms; neuronal function; neuronal homeostasis; neuronal health; neuronal development; neuronal metabolism; neuron– glia interactions; synaptic plasticity; biomarkers of early diagnosis; neurodegeneration; brain diseases
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
Neural Mechanisms Underlying Sensorimotor Learning and Plasticity: Novel Advances and Future Perspectives
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 6593 | Submission Open
Keywords: sensorimotor learning; brain plasticity; cognitive neuroscience; neurophysiology; non-invasive brain stimulation; EEG; neuromodulation; motor system; visual system; somatosensory system
(This special issue belongs to the Section Systems Neuroscience)
Recent Advances in Assessment and Rehabilitation of Communication and Language Disorders: Enhancing Innovations, Neuromodulation and AI submission deadline 31 Dec 2025 | 3 articles | Viewed by 3686 | Submission Open
Keywords: lifespan speech and language disorders; lifespan communication disorders; special learning disabilities; lifespan voice and swallowing disorders; assessment; intervention; innovations; neuromodulation; artificial intelligence
(This special issue belongs to the Section Neurolinguistics)
The Future of Human–Machine Collaboration: AI in Neural Rehabilitation and Assistive Technologies
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 3298 | Submission Open
Keywords: artificial intelligence; neural rehabilitation; brain– computer interface; neuroprosthetics; machine learning; rehabilitation robotics; neuroengineering; assistive technology; wearable devices; neurosignal processing
(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
Lifestyle and Risk Factors for Multiple Sclerosis submission deadline 31 Dec 2025 | 1 articles | Viewed by 2181 | Submission Open
Keywords: multiple sclerosis; lifestyle; risk factors; nutrition; pollution; sleep quality; progression
(This special issue belongs to the Section Neurodegenerative Diseases)
Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders
edited by and Ana Lucia De Paul
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2094 | Submission Open
Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Substance Abuse in the Psychiatric Population submission deadline 31 Dec 2025 | 2 articles | Viewed by 1936 | Submission Open
Keywords: substance abuse disorder; genetics (expression; SNPs); epigenetics; schizophrenia; forensic psychiatry; depression; bipolar disorder; translational research; personality disorders; imaging (PET; SPECT; MRI); general psychiatry
(This special issue belongs to the Section Neuropsychiatry)
Advances in Psychopharmacology in Neurodevelopmental Disorders (NDDs)
edited by Shoumitro Deb
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1739 | Submission Open
Keywords: neurodevelopmental disorders; psychopharmacology; research; recent advances; mental health medicine
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Neuroscience of Learning, Mental Health, and Cultural Adaptation: Cognitive, Pedagogical, and Psychological Perspectives submission deadline 31 Dec 2025 | Viewed by 447 | Submission Open
Keywords: cognitive neuroscience; mental health and learning; cultural adaptation; educational neuroscience; neuropsychology of learning; pedagogical interventions; emotional resilience in education; multicultural and inclusive education; neural mechanisms of learning; cross-cultural pedagogy
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
New Advances in Functional Neurosurgery—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 305 | Submission Open
Keywords: functional neurosurgery; trigeminal neuralgia; microvascular decompression; deep brain stimulation; neuromodulation; spinal cord stimulation; epilepsy surgery; neurophysiological intraoperative monitoring; artificial intelligence in neurosurgery; MR-guided focused ultrasound (MRgFUS); laser interstitial thermal therapy (LiTT)
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Quantifying Motor Neurone Disease: Advances and Challenges in Developing Biomarkers, Predictive Models and Outcome Measures
edited by Roisin McMackin and
submission deadline 31 Dec 2025 | Viewed by 269 | Submission Open
Keywords: amyotrophic lateral sclerosis; primary lateral sclerosis; progressive muscular atrophy; biomarkers (cognition; neurophysiology; biofluid markers; neuroimaging); modelling; therapeutic development; early detection and diagnosis; precision medicine
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Advanced Neuromodulation Therapies for Chronic Pain and Psychiatric Disorders
edited by and Marina de Goes Salvetti
submission deadline 31 Dec 2025 | Viewed by 223 | Submission Open
Keywords: repetitive transcranial magnetic stimulation (rTMS); theta burst stimulation (TBS); chronic pain; treatment-resistant depression; neuromodulation; tDCS; tACS; non-invasive brain stimulation; neuroplasticity; functional connectivity; major depressive disorder and generalized anxiety disorder
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Applications of Cognitive Behavioral Therapy in Mental Disorders
edited by Maria Rita Sergi
submission deadline 31 Dec 2025 | Viewed by 210 | Submission Open
Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions
Multiple Sclerosis Across the Age Spectrum—Beyond Inflammation
edited by
submission deadline 1 Jan 2026 | Viewed by 178 | Submission Open
Keywords: multiple sclerosis; neurodegeneration; disability; cognition; functional outcomes; rehabilitation; pediatric-onset; late onset; ageing
Neural Mechanisms Underlying Social Cognition and Emotional Processing
edited by
submission deadline 10 Jan 2026 | 4 articles | Viewed by 5274 | Submission Open
Keywords: social cognition; emotional processing; social neuroscience; developmental neuroscience
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Deep Research into Stroke
edited by
submission deadline 15 Jan 2026 | 2 articles | Viewed by 4857 | Submission Open
Keywords: stroke; rehabilitation; neuromodulation; physical therapy; robotics; artificial intelligence; neuroimaging; deep learning; machine learning; exercise
(This special issue belongs to the Section Neurorehabilitation)
Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease
edited by Yuta Katsumi, and Bradford C. Dickerson
submission deadline 15 Jan 2026 | 3 articles | Viewed by 2642 | Submission Open
Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Beyond Boundaries: Current Advances in Developmental Learning Disorders
edited by Daniela Traficante and
submission deadline 15 Jan 2026 | 1 articles | Viewed by 1297 | Submission Open
Keywords: developmental learning disorders; transdiagnostic approach; comorbidity; domain-general components
(This special issue belongs to the Section Neuropsychology)
Non-Invasive Neurotechnologies for Cognitive Augmentation submission deadline 15 Jan 2026 | 1 articles | Viewed by 252 | Submission Open
Keywords: neurotechnology; brain– computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology
(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
Inflammation and Central Nervous System
edited by
submission deadline 15 Jan 2026 | Viewed by 147 | Submission Open
Keywords: inflammation; inflammasome; brain injury; neurodegeneration; aging; cognition; brain senescence
(This special issue belongs to the Section Systems Neuroscience)
Anxiety, Depression and Stress
edited by
submission deadline 18 Jan 2026 | 7 articles | Viewed by 8627 | Submission Open
Keywords: anxiety; depression; stress; NMDA modulators; brain stimulation; anti-inflammatory agents; psychosocial interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Perception Across Disciplines: Exploring the Intersections of Cognitive, Social, Affective and Neural Dimensions
edited by
submission deadline 18 Jan 2026 | 1 articles | Viewed by 1680 | Submission Open
Keywords: sensory processing; cognitive systems; perception-action binding; multimodal processing; neural foundations; socio-affective systems; computational models; interdisciplinary research
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition
edited by
submission deadline 20 Jan 2026 | 4 articles | Viewed by 11751 | Submission Open
Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Brain Boosting: Recent Advances in Neurostimulation on Cognitive Functions and Behavioral Performance
edited by
submission deadline 20 Jan 2026 | 2 articles | Viewed by 3252 | Submission Open
Keywords: TMS; cognitive functions; behavioral interventions; brain plasticity; addictions; hypnosis; neurostimulation
(This special issue belongs to the Section Behavioral Neuroscience)
Translational EEG Biomarkers in Animal Models: Bridging Pre-Clinical Findings to Human Neuroscience
edited by and Cestmir Vejmola
submission deadline 20 Jan 2026 | 2 articles | Viewed by 2749 | Submission Open
Keywords: EEG; ECoG; biomarker; animal model; pre-clinical
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Advances in the Treatment of Depression, Anxiety, and Other Psychiatric Disorders
edited by Danielle S. Cha
submission deadline 20 Jan 2026 | Viewed by 391 | Submission Open
Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease
(This special issue belongs to the Section Neuropsychiatry)
Neuropathic Pain: Pathophysiology, Diagnosis and Treatment
edited by Marcos Brioschi and
submission deadline 20 Jan 2026 | Viewed by 133 | Submission Open
Keywords: neuropathic pain; pathophysiology; diagnosis; neuroimaging; thermography; artificial intelligence; treatment; rehabilitation; translational research; neuromodulation
(This special issue belongs to the Section Sensory and Motor Neuroscience)
The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System
edited by
submission deadline 23 Jan 2026 | 2 articles | Viewed by 9802 | Submission Open
Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
Emerging Trends in Youth Mental Health
edited by
submission deadline 23 Jan 2026 | 1 articles | Viewed by 1487 | Submission Open
Keywords: mental health; adolescent mental health; young adult; stress; psychological; social media; climate change; identity development; digital health; school health services
(This special issue belongs to the Section Neuropsychology)
Assessment and Rehabilitation of Cognitive Function in Neurological Disorders
edited by Gilles Naeije
submission deadline 25 Jan 2026 | 2 articles | Viewed by 2018 | Submission Open
Keywords: post-stroke cognitive impairment; diaschisis; cerebellum; cortico-cerebellar connectivity; neuromodulation; transcranial cerebellar stimulation; cognitive rehabilitation; functional connectivity
(This special issue belongs to the Section Neurorehabilitation)
Advances in Neurofeedback Research
edited by
submission deadline 25 Jan 2026 | 1 articles | Viewed by 1323 | Submission Open
Keywords: neurofeedback; brain– computer interface; neurophenomenology; EEG; rt-fMRI; fNIRS-neurofeedback
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Current Research in Neurosurgery
edited by , Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque
submission deadline 30 Jan 2026 | 8 articles | Viewed by 14995 | Submission Open
Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Advances in the Relationship Among Brain, Physical Function, and Exercise Performance
edited by
submission deadline 30 Jan 2026 | 7 articles | Viewed by 13040 | Submission Open
Keywords: physical performance; dual task; cognition; sport; environment; cerebellum; movement; neurodegenerative disease
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Brain Tumors: From Molecular Basis to Therapy
edited by Paolo Tini and Giuseppe Minniti
submission deadline 30 Jan 2026 | 5 articles | Viewed by 8758 | Submission Open
Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance
(This special issue belongs to the Section Neuro-oncology)
Management of Acute Stroke
edited by and Ali Hammed
submission deadline 30 Jan 2026 | 5 articles | Viewed by 7208 | Submission Open
Keywords: management in acute stroke care; thrombolysis; mechanical thrombectomy; epidemiology in stroke care; stroke unit; cerebral infarction; intracranial bleeding; therapy in acute stroke
(This special issue belongs to the Section Systems Neuroscience)
The Relationship Between Sleep and the Brain: New Insights into Sleep Disorders and Their Effects on Mental Health, Cognition, and Quality of Life
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 26277 | Submission Open
Keywords: sleep; REM sleep; circadian rhythm; melatonin; mood disorders; delta sleep; clock genes
(This special issue belongs to the Section Sleep and Circadian Neuroscience)
Advances in Memory and Cognitive Decline Associated with Aging and Alzheimer's Disease
edited by
submission deadline 31 Jan 2026 | 9 articles | Viewed by 24553 | Submission Open
Keywords: neurodegeneration; neuroprotection; neurogenesis; learning and memory; engram; neuro-vascular
(This special issue belongs to the Section Neurodegenerative Diseases)
Advanced Clinical Diagnosis, Evaluation, and Treatment of Psychosis
edited by Giulia Menculini and
submission deadline 31 Jan 2026 | 6 articles | Viewed by 15199 | Submission Open
Keywords: psychotic disorders; affective psychoses; schizophrenia; antipsychotic drugs; psychosocial treatments; at-risk mental states; biomarkers; early intervention; prevention; social psychiatry
(This special issue belongs to the Section Neuropsychiatry)
The Eye as the Window to Brain Science: Fields of Neuroscience Created from Eye Research
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 4956 | Submission Open
Keywords: sensory system functions; neuroanatomy; neurochemistry; neurophysiology; developmental neurobiology; neurological health and disease
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Advances in the Diagnosis, Visualization and Treatment of Intracranial Aneurysms and Subarachnoid Hemorrhage
edited by and Lukas Andereggen
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3863 | Submission Open
Keywords: neurovascular; intracranial aneurysm; subarachnoid hemorrhage; education and teaching; imaging technology; hybrid operating room; augmented reality; cerebrovascular disease; cost-effectiveness; artificial intelligence
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Outcome Measures in Rehabilitation submission deadline 31 Jan 2026 | 1 articles | Viewed by 3845 | Submission Open
Keywords: outcome measures; qualitative measures; quantitative measures; neurologic rehabilitation; musculoskeletal rehabilitation; cardiopulmonary rehabilitation; robotic rehabilitation; movement analysis; gait analysis
(This special issue belongs to the Section Neurorehabilitation)
Mechanisms That Support Music Learning and Development
edited by Jennifer A. Bugos
submission deadline 31 Jan 2026 | Viewed by 308 | Submission Open
Keywords: music; music therapy; neurophysiological research; cognitive development; music cognition; performance; auditory processing
(This special issue belongs to the Section Behavioral Neuroscience)
Deep Brain Stimulation (DBS)—Current Status and Future Directions
edited by Yousef Salimpour
submission deadline 31 Jan 2026 | Viewed by 216 | Submission Open
Keywords: deep brain stimulation; neuromodulation; adaptive closed-loop systems; directional leads; neural biomarkers artificial intelligence; personalization treatment; biocompatible materials
(This special issue belongs to the Section Neurodegenerative Diseases)
Translational Neuroanatomy: Recent Updates and Future Perspectives—2nd Edition
edited by and Andrzej Żytkowski
submission deadline 10 Feb 2026 | 3 articles | Viewed by 1872 | Submission Open
Keywords: neuroanatomy; clinical neuroscience; central or peripheral nervous system
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
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