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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Dementia and Cognitive Decline in Aging

edited by

Yvonne Leung

submission deadline 31 Mar 2026 | 3 articles | Viewed by 1543 | Submission Open

Keywords: dementia; cognitive impairment; Alzheimer’ s disease; mild cognitive impairment (MCI); neurodegeneration; cognitive aging; biomarkers; cognitive resilience; cognitive reserve

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Plasticity of Sensory Cortices: From Basic to Clinical Research

edited by Stephanie Clarke and Sonia Crottaz-Herbette

submission deadline 31 Mar 2026 | 1 articles | Viewed by 622 | Submission Open

Keywords: tonotopy; retinotopy; somatotopy; vestibular; olfactory; gustatory; training-induced plasticity; postlesional plasticity; cochlear implant; prostheses

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Emerging Trends and Perspectives in the Neuroscience of Pain

edited by Martina Rekatsina and

Panagiotis Zis

submission deadline 31 Mar 2026 | Viewed by 151 | Submission Open

Keywords: neuroscience of pain; neuroimaging techniques; neuromodulation therapies; pain mechanisms; chronic pain

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Stress and Trauma Revisited: Oxytocin, Sociostasis, and Hormesis—Missing Pieces of an Evolving Puzzle

edited by C. Sue Carter, Marcy Kingsbury and Hans Nazarloo

submission deadline 31 Mar 2026 | Viewed by 134 | Submission Open

Keywords: oxytocin; vasopressin; stress; sociostasis; hormesis

(This special issue belongs to the Section Systems Neuroscience)

Shaping the Brain in Sleep: Neurodevelopmental Mechanisms Across the Lifespan

edited by Sally Staton, Jasneek Chawla and Kartik Iyer

submission deadline 31 Mar 2026 | Viewed by 134 | Submission Open

Keywords: sleep; brain development; neurodevelopment; sensitive periods; napping; genetic and environmental influences; early childhood; adolescents; adulthood; lifespan development

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Neuroimmune Crosstalk in Neurological Disorders: Mechanistic Insights to Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 31 Mar 2026 | Viewed by 120 | Submission Open

Keywords: neuroinflammation; neuroimmune system; glial cell dynamics; immune cell trafficking; cyto-kine signaling; neurological disorders; immune modulation

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Psychiatry and Addiction: A Multi-Faceted Issue—2nd Edition

edited by

Fabrizio Schifano

Norbert Scherbaum

and

Giovanni Martinotti

submission deadline 31 Mar 2026 | Viewed by 96 | Submission Open

Keywords: addiction spectrum disorders; substance misuse; dual disorders; alcohol misuse; prescription drug misuse; dopamine; neurotransmitter pathways; reward systems; addiction treatment; reward deficit syndrome; translational anti-craving medications; food addiction; sex addiction; internet gaming disorder; gambling; novel antidiabetics; salience; novel psychoactive substances (NPSs); prescription drug misuse; brain– gut axis; microbiome

(This special issue belongs to the Section Behavioral Neuroscience)

Advances in Immune-Mediated Disorders of the Nervous System in Childhood

edited by Martino Ruggieri and

Andrea Domenico Praticò

submission deadline 10 Apr 2026 | Viewed by 218 | Submission Open

Keywords: autoimmune encephalitis; pediatric neuroinflammation; immune-mediated CNS disorders; childhood multiple sclerosis; MOG antibody disease; neuroimmunology; immunotherapy in children; neuromyelitis optica

(This special issue belongs to the Section Developmental Neuroscience)

New Perspectives on Language Processing in Aging

edited by Andrea Marini

submission deadline 15 Apr 2026 | 1 articles | Viewed by 1171 | Submission Open

Keywords: aging; language; cognition; phonology; lexical skills; grammatical skills; pragmatics; discourse; neuropsychology of language

(This special issue belongs to the Section Neurolinguistics)

Gait and Balance Analysis in Parkinson’s Disease

edited by Timothy Adam Thrasher

submission deadline 15 Apr 2026 | Viewed by 107 | Submission Open

Keywords: Parkinson’ s disease; gait; postural instability; falls; rehabilitation

(This special issue belongs to the Section Neurodegenerative Diseases)

Clinical Translation in Disorders of Consciousness: New Pathways and Challenges

edited by

Caroline Schnakers

and

Katherine O'Brien

submission deadline 15 Apr 2026 | Viewed by 74 | Submission Open

Keywords: disorders of consciousness; brain injury; consciousness; coma

(This special issue belongs to the Section Systems Neuroscience)

Neural–Immune Interactions: Understanding the Bidirectional Relationship between the Brain and Immune Cells

edited by

Enrique Becerril-Villanueva

, Alberto Salazar-Juárez and María Dolores Ponce-Regalado

submission deadline 16 Apr 2026 | 2 articles | Viewed by 3316 | Submission Open

Keywords: neuroimmunology; neuroimmunoendocrinology; psychiatric disorders; psycho-oncology; infectious diseases; sickness behavior; neurotransmitters; cytokines; hormones

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Neuropsychological Impact and Quality of Life in Chronic Illness

edited by

Nicoletta Ciccarelli

and

Elisa Pini

submission deadline 20 Apr 2026 | 3 articles | Viewed by 4354 | Submission Open

Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures

(This special issue belongs to the Section Neuropsychology)

Cerebral Amyloid Angiopathy: Advances in the Field

edited by Ulf Jensen-Kondering and

Benedetta Storti

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2431 | Submission Open

Keywords: cerebral amyloid angiopathy; cerebral small vessel disease; cerebral hemorrhage; vascular dementia; stroke; amyloid; CAA-ri; iatrogenic CAA

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Brain Mechanisms of Hot and Cold Executive Function in Healthy and Clinical Populations

edited by

Sandra Carvalho

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2049 | Submission Open

Keywords: executive function; hot executive function; cold executive function; cognitive control; emotion; cognition interaction; emotion regulation; transdiagnostic mechanisms

(This special issue belongs to the Section Behavioral Neuroscience)

Brain Plasticity and Motor Control—3rd Edition

edited by

Bernadette Murphy

submission deadline 20 Apr 2026 | Viewed by 137 | Submission Open

Keywords: brain; neuroplasticity; motor control; sensorimotor integration; sensory input

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Addressing ADHD in Children: Contemporary Treatment Strategies

edited by Richard Gallagher

submission deadline 20 Apr 2026 | Viewed by 101 | Submission Open

Keywords: ADHD (attention deficit hyperactivity disorders); children; adolescent; executive function deficits and treatment; functional impairments; psychosocial interventions; brain activity-targeted treatments

(This special issue belongs to the Section Developmental Neuroscience)

Neuroregulatory Factors in Neurodevelopmental Plasticity: From Stem Cell Differentiation to Neural Circuit Maturation

edited by

Anayansi Molina-Hernández

submission deadline 20 Apr 2026 | Viewed by 61 | Submission Open

Keywords: neurodevelopmental plasticity; neural stem cells; differentiation; neural circuit maturation; epigenetic regulation; synaptic plasticity; neurodevelopmental disorders; translational neuroscience

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Beyond the Brain: Merging Embodied Mind and AI in the Clinical Neuroscience of Psychotherapy

edited by

Raffaele Sperandeo

and

Valeria Cioffi

submission deadline 24 Apr 2026 | 3 articles | Viewed by 7026 | Submission Open

Keywords: holistic approach; psychotherapy; neuroscience; complex systems; self-organization; interdisciplinary research; artificial intelligence; embodied mind

(This special issue belongs to the Section Neuropsychology)

Molecular and Cellular Research in Neurodegenerative Diseases

edited by

Kallirhoe Kalinderi

submission deadline 25 Apr 2026 | 2 articles | Viewed by 4388 | Submission Open

Keywords: neurodegenerative diseases; Parkinson’ s disease; Alzheimer’ s disease; Huntington’ s disease; amyotrophic lateral sclerosis; gene; mechanism; molecular; cellular; pathophysiology

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Global Sleep and Circadian Health

edited by

Lourdes DelRosso

submission deadline 30 Apr 2026 | 3 articles | Viewed by 20478 | Submission Open

Keywords: global sleep health; sleep medicine; sleep disorders; sleep disparities; sleep diagnostics; circadian effects on sleep health; shift work disorder and productivity; chronic diseases and sleep; sleep and mental health; sleep health equity; representation in sleep research (age; gender); primary care and sleep; social determinants of sleep health; cross-cultural sleep health

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Psychedelic and Interventional Psychiatry

edited by

Mark S. Gold

submission deadline 30 Apr 2026 | 4 articles | Viewed by 11518 | Submission Open

Keywords: psychedelics; ketamine; interventional psychiatry; psychedelic medicine; LSD; DMT; psilocybin; MDMA; depression; anxiety; end of life; palliative medicine; treatment-resistant depression; OCD; anorexia nervosa; eating disorders; nitrous oxide; TMS; DBS; alcohol use disorders; substance use disorders; trauma; post-traumatic stress disorders; PTSD; ketamine and other psychedelic use disorders

(This special issue belongs to the Section Neuropsychiatry)

Advances in Face Perception and How Disorders Affect Face Perception

edited by Karen Lander, Rachel Bennetts and Natalie Butcher

submission deadline 30 Apr 2026 | 5 articles | Viewed by 5244 | Submission Open

Keywords: face perception; face recognition; prosopagnosia; neurodevelopmental disorders; individual differences; clinical disorders

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Review in Neuropsychology: Advances and Future Directions

edited by

Sara Palermo

Pierluigi Zoccolotti

and

Laura Piccardi

submission deadline 30 Apr 2026 | Viewed by 816 | Submission Open

Keywords: aphasia; attentional disorders; hemineglect; amnesia; apraxia; neurodevelopmental disorders; neuropsychological approach; neuroscience

(This special issue belongs to the Section Neuropsychology)

New Insights into Mental Health Research for Neurological and Psychiatric Disorders

edited by

Francesco Corallo

and

Lilla Bonanno

submission deadline 30 Apr 2026 | 1 articles | Viewed by 452 | Submission Open

Keywords: neuropsychiatric disorders; mental health; neurological conditions; comorbidity; integrated care; interventions; digital health; neuroimaging; artificial intelligence; personalized medicine

(This special issue belongs to the Section Neuropsychiatry)

Innovations in Pediatric Functional Neurosurgery

edited by Samuel Tomlinson and Benjamin C. Kennedy

submission deadline 30 Apr 2026 | Viewed by 204 | Submission Open

Keywords: pediatric neurosurgery; functional neurosurgery; epilepsy; movement disorders; spasticity; dystonia; surgical innovation; minimally invasive surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Neuroimaging of Cerebral Small Vessel Disease

edited by Sheelakumari Raghavan

submission deadline 30 Apr 2026 | Viewed by 156 | Submission Open

Keywords: Small Vessel Disease; neuroimaging; MRI; cognitive impairment; imaging biomarkers

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Intracranial Aneurysms

edited by Mario Zuccarello and Sudhakar Vadivelu

submission deadline 30 Apr 2026 | Viewed by 148 | Submission Open

Keywords: intracranial aneurysms; natural history; improved diagnosis; minimally invasive treatment; device development; molecular mechanisms; emerging drug therapies; artificial intelligence; prevention strategies; public education

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Advances in Parkinson's Disease and Other Movement Disorders

edited by Quincy J. Almeida

submission deadline 30 Apr 2026 | Viewed by 98 | Submission Open

Keywords: Parkinson’ s disease; movement disorders; artificial intelligence; machine learning; gait; relevant mechanisms; freezing; tremor

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Perspectives on Brain Tumor: From Basic Studies to Clinical Treatment and Rehabilitation

edited by Luca Zigiotto and Silvio Sarubbo

submission deadline 30 Apr 2026 | Viewed by 96 | Submission Open

Keywords: brain tumor surgery; awake surgery; cognitive impairments and rehabilitation; neuropsychology; brain functional networks; structural and functional connectivity; white matter fibers; quality of life; high-grade gliomas; low-grade gliomas

(This special issue belongs to the Section Neuro-oncology)

Cognitive Training and Physical Exercise: Evidence-Based Strategies for Healthy Aging

edited by

Takao Yamasaki

submission deadline 30 Apr 2026 | Viewed by 86 | Submission Open

Keywords: cognitive training; physical exercise; healthy aging; mild cognitive impairment; dementia; cognitive decline; neuroplasticity; brain health; executive function; memory

(This special issue belongs to the Section Systems Neuroscience)

New Approaches to Prevent Neuropsychiatric Disorders Through the Control of Neuroinflammation

edited by Yoshikaszu Matsuda

submission deadline 30 Apr 2026 | Viewed by 83 | Submission Open

Keywords: neuroinflammation; Alzheimer's disease; microglia; neuroprotective effect; neuropsychiatric disorders; smoldering inflammation

(This special issue belongs to the Section Neurodegenerative Diseases)

Neuroscience: Advances in Nanotechnologies

edited by Mohammednadim Sardoiwala

submission deadline 30 Apr 2026 | Viewed by 73 | Submission Open

Keywords: nanomedicine; neurotherapeutics; neuro-oncology; nano-bioimaging; diagnosis; neural regeneration

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Progress in Prosopagnosia Research

edited by

Andrea Albonico

submission deadline 30 Apr 2026 | Viewed by 65 | Submission Open

Keywords: prosopagnosia; face recognition; treatment; diagnosis; development; face blindness

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

The Neural Processes Underlying Parkinson’s Disease and Related Synucleinopathies

edited by Danielle E. Mor

submission deadline 5 May 2026 | Viewed by 307 | Submission Open

Keywords: α -synuclein; synucleinopathies; Parkinson’ s disease; dementia with Lewy bodies; multiple system atrophy; neurodegeneration; protein aggregation

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Dopamine and Cognition

edited by

Luca Aquili

submission deadline 10 May 2026 | 1 articles | Viewed by 3775 | Submission Open

Keywords: dopaminergic system; cognitive neuroscience; reinforcement learning; neuropsychopharmacology; motivation and decision making

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Accessing Treatment and Rehabilitation for Underserved Survivors of Brain Injury

edited by Eve M. Valera

submission deadline 10 May 2026 | Viewed by 166 | Submission Open

Keywords: TBI; brain injury; partner violence; incarcerated; homeless; rehabilitation; strangulation; criminal justice system; barriers

Editorial Board Collection Series: Advances in Neuro-Oncology

edited by

Terry Lichtor

submission deadline 15 May 2026 | 9 articles | Viewed by 18475 | Submission Open

Keywords: brain tumors; gliomas; cytokine gene vaccine therapy; immunotherapy; angiogenesis; checkpoint inhibitors; dendritic cell therapy

(This special issue belongs to the Section Neuro-oncology)

Rethinking Neurodevelopmental Disorders: Beyond One-Size-Fits-All

edited by Salman Zubedat

submission deadline 15 May 2026 | 1 articles | Viewed by 3177 | Submission Open

Keywords: ADHD; autism; intellectual disability; communication disorders

(This special issue belongs to the Section Developmental Neuroscience)

Innovation on Neuropsychological and Cognitive Changes in Aging: Assessment and Intervention

edited by Renata Kochhann, Laiss Bertola and

Bernardino Fernández-Calvo

submission deadline 15 May 2026 | 1 articles | Viewed by 963 | Submission Open

Keywords: aging; dementia; neuropsychology; neuropsychological test; non-pharmacological interventions

(This special issue belongs to the Section Neuropsychology)

The Interplay Between the Brain, Behavior and Immunity

edited by

Fatme Seval Ismail

submission deadline 15 May 2026 | Viewed by 500 | Submission Open

Keywords: behavior; therapy; drugs; immunity; neuroinflammation; neurological/psychiatric disorders; clinical studies; in vivo/in vitro models

(This special issue belongs to the Section Behavioral Neuroscience)

Personalised Treatment and Diagnosis of Sleep Disorders

edited by

Dagmara Dimitriou

, Zaid Awad and Mustafa Jaafar

submission deadline 15 May 2026 | Viewed by 131 | Submission Open

Keywords: sleep disorders; obstructive sleep apnoea; personalized treatment; diagnosis; neurodivergence; comorbidities; cross-cultural sleep; wearable technology; paediatric sleep; public health

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Clinical Research on Pain: Advances and Challenges

edited by Mariateresa Giglio

submission deadline 20 May 2026 | 1 articles | Viewed by 739 | Submission Open

Keywords: pain management; chronic pain; pain research; analgesia; multidisciplinary approach

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Controversies and Challenges in Vestibular Medicine

edited by

Alexander A. Tarnutzer

and

Diego Kaski

submission deadline 20 May 2026 | Viewed by 145 | Submission Open

Keywords: vestibular medicine; emerging treatments; vestibular migraine; controversies in neuro-otology; Meniè re’ s disease; acute vertigo and dizziness

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in Psychosocial and Neurological Aspects in Supportive Cancer Care

edited by

Philip R. Debruyne

Patricia Schofield

and

Laura Tack

submission deadline 22 May 2026 | 1 articles | Viewed by 1507 | Submission Open

Keywords: supportive cancer care; neuropsychology; psychosocial; quality of life; pain management

(This special issue belongs to the Section Neuropsychology)

Mechanisms Underlying the Neuropathic/Chronic Pain Development and Maintenance: Focus on Pharmacological Targets and Therapeutic Approaches

edited by

Giada Amodeo

submission deadline 25 May 2026 | 3 articles | Viewed by 10165 | Submission Open

Keywords: neuropathic pain; chronic pain; mood alteration; neurons; glia cells; cytokines; neuroinflammation

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Effect of Lifestyle on Brain Aging and Cognitive Function

edited by

Shuzo Kumagai

Takao Yamasaki

and

Yung Liao

submission deadline 25 May 2026 | Viewed by 293 | Submission Open

Keywords: cognitive function; brain aging; lifestyle; mild cognitive impairment; dementia; prevention and intervention; genetic-environment interaction

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Advances in Circadian Rhythms, Sleep, and Cognitive Function: Translational and Technological Perspectives

edited by

Maria Comas Soberats

submission deadline 25 May 2026 | Viewed by 133 | Submission Open

Keywords: sleep; circadian rhythms; cognitive function; translational research; telemedicine; wearable technology; light therapy; cognitive behavioral therapy; sleep interventions; neurodevelopmental disorders; neurodegenerative disorders; elderly; adolescence; shift work; non-clinical populations; digital health; chronobiology; sleep health; sleep disorders; circadian disruption; at-risk populations

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Social and Emotional Processes in Interpersonal Contexts

edited by

Yaoying Xu

and

Yuyan Xia

submission deadline 29 May 2026 | Viewed by 181 | Submission Open

Keywords: social; emotional; social– emotional; interpersonal; cultural relevance; neuroscience; social interaction; interdisciplinary

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Clinical Research on Parkinson’s Disease: Opportunities and Challenges (2nd Edition)

edited by

Santiago Perez-Lloret

, Matilde Otero-Losada and Francisco Capani

submission deadline 30 May 2026 | 2 articles | Viewed by 2364 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; clinical research; epidemiology; non-motor symptoms; quality of life; technology; observational studies; randomized controlled trials

(This special issue belongs to the Section Neurodegenerative Diseases)

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