Advanced Optical Biosensing: Design, Materials and Practical Applications

Dear Colleagues,

Recent advances in optical biosensing are reshaping analytical science by enabling rapid, label-free, sensitive, and potentially portable detection platforms for biomedical diagnostics, environmental monitoring, food safety, security, and biodefence. The integration of innovative optical transduction schemes, engineered materials, nanostructured interfaces, and robust molecular recognition strategies is opening new routes toward practical optical biosensors with improved selectivity, reproducibility, miniaturization, and field applicability. This Special Issue aims to collect high-quality original research articles, reviews, and short communications focused on the design, fabrication, characterization, and validation of advanced optical biosensing systems. Topics of interest include, but are not limited to, surface plasmon resonance sensors combined with molecular recognition elements (MREs), fiber-optic platforms for biosensing strategies, fluorescence-based biosensors, photonic and plasmonic nanostructures for sensing, molecular recognition layers (e.g., biological or biomimetic), biofunctionalization protocols, microfluidic integration, point-of-care devices, and data-assisted sensing approaches. Particular attention will be given to contributions that connect material/interface design with analytical performance and real-sample applications. Studies addressing biosensor reliability, selectivity, matrix effects, device portability, and translational potential are especially encouraged. Finally, innovative optical sensing principles that exploit new schemes, approaches, and materials are of interest to this Special Issue.

Dr. Mimimorena Seggio
Guest Editor

Dr. Rosalba Pitruzzella
Guest Editor Assistant

Manuscript Submission Information

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