Cutting-Edge Research on the Analysis of Small Biomolecules in Foods, Plants, and Biological Samples, 2nd Edition

Dear Colleagues,

Following a very successful first run, we are pleased to announce the launch of the second edition of a Special Issue on ‘Cutting-Edge Research on the Analysis of Small Biomolecules in Foods, Plants, and Biological Samples’.

Small organic biomolecules that are contained in foods or derived from plants (natural products) are increasingly being recognized as biomolecules that can regulate and control cellular function. It is widely accepted that various foods and plant extracts are associated with effects against diseases, such as metabolic and cardiovascular diseases and cancer, due to the presence of bioactive primary and secondary metabolites. For example, polyphenols are plant secondary metabolites that are ubiquitous in fruits, vegetables, and cereals, which have been positively associated with numerous health benefits. Lipids constitute another example of small biomolecules, which may play a role in the protection and promotion of human health. Although the exact mechanisms of action of the food ingredients are mostly unclear and under continuous investigation, there is a great demand for analytical methods for the sensitive and precise determination of small bioactive molecules in food, plant, and biological samples.

Analytical approaches that employ mass spectrometry (MS) have been recognized as powerful and rapidly growing technologies that can be used in biomedical and natural product research not only to identify novel bioactive small molecules, but also to study disease mechanisms. MS combined with either liquid chromatography (LC–MS) or gas chromatography (GC–MS) is the major technique used for the detection and determination of small bioactive molecules in various matrices. In particular, high-resolution mass spectrometry (HRMS) offers the high sensitivity and high mass accuracy required for the detection and quantification of low-abundance small biomolecule species. Fourier transform infrared (FTIR) and Raman spectroscopy are complementary techniques for the analysis of small biomolecules. The aim of the present Special Issue is to compile review articles and original research articles covering recent advances in the analysis of small bioactive molecules (primary and secondary metabolites) in foods, plants, and biological samples.

Dr. Maroula Kokotou
Prof. Dr. Petros Tarantilis
Dr. Christos Pappas
Guest Editors

Manuscript Submission Information

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