Special Issue "Advances in Plasma Bioscience and Medicine"

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biophysics".

Deadline for manuscript submissions: 23 May 2023 | Viewed by 1124

Special Issue Editors

1. Laboratory of Thermal Physics of Multiphase Systems, Arifov Institute of Ion-Plasma and Laser Technologies, Academy of Sciences of Uzbekistan, Tashkent 100125, Uzbekistan
2. Research Group PLASMANT, Department of Chemistry, University of Antwerp, 2610 Antwerp, Belgium
Interests: plasma medicine; plasma-biomolecule interactions; computer simulations; molecular dynamics
1. Laboratory of Technical Ceramics and Heat Resistance Materials, Institute of Material Sciences, Academy of Sciences of Uzbekistan, Tashkent 100084, Uzbekistan
2. Institute of Fundamental and Applied Research, National Research University TIIAME, Tashkent 100000, Uzbekistan
Interests: plasma medicine; plasma-biomolecule interactions; computer simulations; molecular dynamics
1. Associate Professor, Center of Plasma Nano-Interface Engineering, Kyushu University, Fukuoka 819-0395, Japan
2. Faculty of Information Science and Electrical Engineering , Kyushu University, Fukuoka 819-0395, Japan
Interests: plasma medicine; protein-folding; plasma-biomolecule interactions; computer simulations; molecular dynamics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite you to submit a review or research article to the Special Issue entitled “Advances in Plasma Bioscience and Medicine”, which we are organizing in collaboration with Biomolecules (IF 6.064; https://www.mdpi.com/journal/biomolecules), an open access journal published by MDPI, Switzerland.

Plasma medicine, i.e., the biomedical application of non-thermal atmospheric pressure plasma (NTP), is gaining increasing interest, with applications in sterilization of microorganisms (i.e., bacteria, fungi and viruses), food decontamination, wound healing and even cancer treatment.

It is widely accepted that the biological and medical effects of NTP are related to reactive oxygen and nitrogen species (RONS). While high doses of NTP-generated RONS are undeniably "harmful" to any cell/organism, delivery of low doses of specific RONS may be beneficial in the aforementioned therapies.

The argument follows that RONS regulate key biochemical pathways within intra- and intercellular environments, inducing chemical and physical modifications in cellular components, oxidizing or breaking them into fragments. Studies have already shown that the treatment of living cells with NTP induces changes in intracellular signaling, which is important in the treatment of diseases. However, it is still unclear how plasma-generated RONS regulate intracellular processes. If these processes are better understood, it will allow the development of more targeted and effective medical plasma therapy.

In this Special Issue of Biomolecules, we aim to offer a platform for high-quality publications focused on the fundamental understanding of the impact of NTP-generated RONS on biomolecules or the implications of these interactions in the context of plasma medicine.

Research areas may include (but are not limited to) the following:

  • Plasma medicine
  • Plasma oncology
  • Plasma disinfection
  • Plasma wound healing
  • Plasma immunotherapy
  • Plasma-activated liquid

We look forward to receiving your contributions.

Dr. Maksudbek Yusupov
Dr. Jamoliddin Razzokov
Dr. Pankaj Attri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • non-thermal (cold) atmospheric pressure plasma
  • reactive oxygen and nitrogen species (RONS)
  • plasma–biomolecule interaction
  • plasma cancer treatment
  • plasma immunomodulation
  • plasma inactivation of viruses, fungi and bacteria
  • plasma–liquid interaction
  • computer simulations

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

Review
Receptor-Mediated Redox Imbalance: An Emerging Clinical Avenue against Aggressive Cancers
Biomolecules 2022, 12(12), 1880; https://doi.org/10.3390/biom12121880 - 15 Dec 2022
Viewed by 706
Abstract
Cancer cells are more vulnerable to abnormal redox fluctuations due to their imbalanced antioxidant system, where cell surface receptors sense stress and trigger intracellular signal relay. As canonical targets of many targeted therapies, cell receptors sensitize the cells to specific drugs. On the [...] Read more.
Cancer cells are more vulnerable to abnormal redox fluctuations due to their imbalanced antioxidant system, where cell surface receptors sense stress and trigger intracellular signal relay. As canonical targets of many targeted therapies, cell receptors sensitize the cells to specific drugs. On the other hand, cell target mutations are commonly associated with drug resistance. Thus, exploring effective therapeutics targeting diverse cell receptors may open new clinical avenues against aggressive cancers. This paper uses focused case studies to reveal the intrinsic relationship between the cell receptors of different categories and the primary cancer hallmarks that are associated with the responses to external or internal redox perturbations. Cold atmospheric plasma (CAP) is examined as a promising redox modulation medium and highly selective anti-cancer therapeutic modality featuring dynamically varying receptor targets and minimized drug resistance against aggressive cancers. Full article
(This article belongs to the Special Issue Advances in Plasma Bioscience and Medicine)
Show Figures

Figure 1

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Cold Atmospheric Plasma's Chemical Modifications on Molecules and Their Biological Effects.
Authors: Dayun Yan, Li Lin, Marisa Lazarus, Ruby Limanowski, Alex Horkowitz, William Murphy, Michael Keidar.
Affiliation: George Washington University, Department of Mechanical and Aerospace Engineering, Department of Biomedical Engineering, Department of Physics.

Back to TopTop