Special Issue "The Value of Natural Compounds as Therapeutic Agents"

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-inspired Molecules".

Deadline for manuscript submissions: 31 December 2022 | Viewed by 579

Special Issue Editor

Special Issue Information

Dear Colleagues,

Naturally occurring substances have long been used by humans for medicinal purposes, as concoctions or concentrated extracts. At present, natural products are gaining popularity. A number of pathological conditions have been treated with plant-derived medicines, including cancer and inflammation.

Therefore, in this Special Issue, we aim to unite experts and scientists who work on natural compounds to gather information and data about their involvement in a wide variety of biological mechanisms at the cellular level. The Special Issue will predominantly focus on cellular processes, such as proliferation and survival, apoptosis, dormancy, differentiation, autophagy and senescence, migration, and invasion. Additionally, analyses of soluble mediators involved with microenvironment modulation will be appreciated.

In summary, we would like to emphasize the existing evidence regarding the various potential advantages of plant extracts and plant extract-based products, in regard to human health. Therefore, we encourage submissions of manuscripts that utilize structurally defined natural products or their derivatives, or well-characterized mixtures. We welcome original research articles, review articles, and communications.

Dr. Maria Beatrice Morelli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural compound
  • acute and chronic conditions
  • cell proliferation
  • cell death
  • cell differentiation

Published Papers (1 paper)

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Review

Review
The Benefits of Anthocyanins against Obesity-Induced Inflammation
Biomolecules 2022, 12(6), 852; https://doi.org/10.3390/biom12060852 - 20 Jun 2022
Viewed by 442
Abstract
Obesity has become a serious public health epidemic because of its associations with chronic conditions such as type 2 diabetes mellitus, hypertension, cardiovascular disease, and cancer. Obesity triggers inflammation marked by the secretion of low-grade inflammatory cytokines including interleukin-6, C-reactive protein, and tumor [...] Read more.
Obesity has become a serious public health epidemic because of its associations with chronic conditions such as type 2 diabetes mellitus, hypertension, cardiovascular disease, and cancer. Obesity triggers inflammation marked by the secretion of low-grade inflammatory cytokines including interleukin-6, C-reactive protein, and tumor necrosis factor-α, leading to a condition known as “meta-inflammation”. Currently, there is great interest in studying the treatment of obesity with food-derived bioactive compounds, which have low toxicity and no severe adverse events compared with pharmacotherapeutic agents. Here, we reviewed the beneficial effects of the bioactive compounds known as anthocyanins on obesity-induced inflammation. Foods rich in anthocyanins include tart cherries, red raspberries, black soybeans, blueberries, sweet cherries, strawberries and Queen Garnet plums. These anthocyanin-rich foods have been evaluated in cell culture, animal, and clinical studies, and found to be beneficial for health, reportedly reducing inflammatory markers. One factor in the development of obesity-related inflammation may be dysbiosis of the gut microbiome. Therefore, we focused this review on the in vitro and in vivo effects of anthocyanins on inflammation and the gut microbiota in obesity. Full article
(This article belongs to the Special Issue The Value of Natural Compounds as Therapeutic Agents)
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