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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances of Amyloid-β Dynamics in Health and Diseases

edited by

Rahat Ullah

submission deadline 28 Feb 2026 | Viewed by 393 | Submission Open

Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Drug Resistance and Novel Targets for Cancer Therapy—Third Edition

edited by

Bruno Kaufmann Robbs

and

Fernando de Carvalho da Silva

submission deadline 28 Feb 2026 | 1 articles | Viewed by 345 | Submission Open

Keywords: cancer; drug resistance; targeted therapy; conventional chemotherapy; natural products; molecular targets; cancer hallmarks; therapeutic agents

(This special issue belongs to the Section Cancer Biology and Oncology)

Human Stem Cells in Disease Modelling and Treatment (2nd Edition)

edited by Sofia M. Calado and

Álvaro Plaza Reyes

submission deadline 28 Feb 2026 | 1 articles | Viewed by 293 | Submission Open

Keywords: induced pluripotent stem cells (iPSCs); embryonic stem cells (ESCs); disease models; cell therapies; cell therapy medicinal products (CTMPs); regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

Recent Advances in Biomedical Engineering for the Elderly

edited by

Siti Anom Ahmad

submission deadline 28 Feb 2026 | Viewed by 274 | Submission Open

Keywords: biomedical engineering; gerontechnology; artificial intelligence in healthcare; digital health; physiological signal processing; human– machine interaction; rehabilitation engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Cancer Treatment

edited by

Vlasios Karageorgos

and

George Liapakis

submission deadline 28 Feb 2026 | Viewed by 269 | Submission Open

Keywords: targeted therapy; bio-conjugates; biologic agents; precision oncology; personalized cancer treatment; biomarker-guided therapy; cancer drug development; biopharmaceuticals

(This special issue belongs to the Section Cancer Biology and Oncology)

Neurotrauma: Mechanisms, Pathways, and Emerging Therapeutic Interventions, 2nd Edition

edited by Kevin Pierre and

Brandon Lucke-Wold

submission deadline 28 Feb 2026 | Viewed by 231 | Submission Open

Keywords: neurotrauma; traumatic brain injury; spinal cord injury; inflammation; oxidative stress; excitotoxicity; diagnostic biomarkers; imaging techniques; neuroprotection; neurogeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Current Challenges and Future Trends in Intracranial Aneurysms: Mechanisms, Biomarkers, and Therapeutic Strategies

edited by Zhongsong Shi and

Aichi Chien

submission deadline 28 Feb 2026 | Viewed by 227 | Submission Open

Keywords: intracranial aneurysm; subarachnoid hemorrhage; inflammation; immune; smooth muscle cell; endothelial dysfunction; hemodynamic forces; biomarkers; neuroimaging; non-coding RNA; multi-omics; endovascular treatment; computational fluid dynamic

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pathogenesis, Diagnosis and Treatment of Endocrine Cancers

edited by

Rajeev Parameswaran

submission deadline 28 Feb 2026 | Viewed by 225 | Submission Open

Keywords: thyroid; parathyroid; adrenal; paraganglioma; genomes; transcriptomes; signalling pathways; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Glioblastoma: From Pathology to Novel Therapeutic Approaches

edited by Carlen A. Yuen

submission deadline 28 Feb 2026 | Viewed by 197 | Submission Open

Keywords: glioblastoma; EGFR; TERT; +7/-10; CAR T-cell therapy; immunotherapy; GammaTile® ; LITT

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Immune and Metabolic Dysregulation in Neurological and Neuropsychiatric Disorders

edited by

Qingkun Liu

and

Xin-An Liu

submission deadline 28 Feb 2026 | Viewed by 194 | Submission Open

Keywords: neuroimmune interaction; neuroinflammation; metabolic regulation; gut– brain axis; microbiome; neuroendocrine system; neurodegeneration; psychiatric disorders; brain injuries

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diagnostic and Therapeutic Approaches to Pancreatic Cancer—Second Edition

edited by

Sanchita Rauth

submission deadline 28 Feb 2026 | Viewed by 184 | Submission Open

Keywords: pancreatic cancer; systemic therapy; immunotherapy; tumor microenvironment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Kidney Disease: From Pathophysiology to Treatment

edited by

Paola Pontrelli

and

Francesca Conserva

submission deadline 28 Feb 2026 | Viewed by 172 | Submission Open

Keywords: acute kidney injury; chronic kidney disease; precision medicine; molecular mechanisms; biomarkers; therapeutic response

Novel Insight into Human Reproductive Medicines

edited by

Bo Huang

submission deadline 28 Feb 2026 | Viewed by 167 | Submission Open

Keywords: IVF; oocyte; sperm; clinical outcome; embryo; ovulation induction; fertilization; PGT

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Innovative Strategies for the Diagnosis and Treatment of Sarcopenia and Osteoporosis

edited by Wei-Bin Hsu and

Meng-Huang Wu

submission deadline 28 Feb 2026 | Viewed by 162 | Submission Open

Keywords: sarcopenia; osteoporosis; healthy aging; bone strength; muscle health; fracture prevention; pharmacological therapies; nutritional support; exercise rehabilitation

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances in Diagnosis and Therapeutic Strategies in Intraocular Inflammation—Second Edition

edited by

Uwe Pleyer

submission deadline 28 Feb 2026 | Viewed by 160 | Submission Open

Keywords: biomarker; diagnosis; immune pharmacology; immune regulation; immune system; infection; uveitis; therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Eicosanoids and Fatty Acids in Health, Diseases and Therapeutics

edited by Mihai Nechifor

submission deadline 28 Feb 2026 | Viewed by 151 | Submission Open

Keywords: eicosanoids; prostaglandins; leukotrienes; prostacyclin; lipoxins; resolvins; protectins; maresins; arachidonic acid (AA); eicosapentaenoic acid (EPA); docosahexaenoic acid (DHA); cell functions; immunity; cardiovascular; neuropsychiatric; metabolic; digestive; reproductive; hematologic; inflammatory and oncologic pathology; therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Emerging Technologies in Liquid Biopsy of Cancers

edited by Lingdi Yin

submission deadline 28 Feb 2026 | Viewed by 148 | Submission Open

Keywords: liquid biopsy; circulating tumor cells (CTCs); circulating tumor DNA (ctDNA); exosomes; cancer diagnostics; biomarker discovery; minimally invasive monitoring; emerging technologies; clinical translation; molecular profiling

(This special issue belongs to the Section Cancer Biology and Oncology)

Diagnosis and Treatment of Periodontal Disease

edited by

Khaing Myat Thu

submission deadline 28 Feb 2026 | Viewed by 144 | Submission Open

Keywords: periodontitis; gingivitis; periimplantitis; artificial intelligence; X-ray; periodontal treatment; plaque control; oral hygiene

(This special issue belongs to the Section Molecular and Translational Medicine)

Research Progress on Antimicrobial Resistance (AMR)

edited by

Tomohiro Oishi

submission deadline 28 Feb 2026 | Viewed by 144 | Submission Open

Keywords: antimicrobial resistance; mechanism; therapy; experiment; bacteria; antibiotics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Anticancer Drugs in Immunotherapy: Molecular Mechanisms, Translational Insights, and Clinical Applications

edited by

Bashir Lawal

submission deadline 28 Feb 2026 | Viewed by 143 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitors; drug synergy; immunogenic cell death; tumor microenvironment; cancer immunology; combination therapy; chemotherapy; targeted therapy; translational oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Immunotherapy and Immune-Related Adverse Events in Cancer

edited by

Ivana Mikolašević

and

Marin Golčić

submission deadline 28 Feb 2026 | Viewed by 139 | Submission Open

Keywords: immunotherapy; cancer; PD-1 inhibitors; immune-related adverse effects; management

(This special issue belongs to the Section Immunology and Immunotherapy)

Decoding Resistance: Molecular Drivers of Therapy Failure in Advanced Prostate Cancer

edited by

Jyoti Kaushal

submission deadline 28 Feb 2026 | Viewed by 139 | Submission Open

Keywords: prostate cancer; androgen deprivation therapy; molecular signaling; epigenetic remodeling; cancer stem cell; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Liver Fibrosis: From Mechanisms to Therapeutics

edited by

Kun Zhang

submission deadline 28 Feb 2026 | Viewed by 135 | Submission Open

Keywords: liver fibrosis; therapeutic target; biomarker; hepatocyte; macrophage; LSEC; HSC; immune cells; extracellular matrix

(This special issue belongs to the Section Molecular and Translational Medicine)

Intestinal Homeostasis and Disease Dysbiosis

edited by

Nikolas Dovrolis

submission deadline 28 Feb 2026 | Viewed by 133 | Submission Open

Keywords: gut microbiota; intestinal homeostasis; dysbiosis; microbiota– drug interactions; host– microbe interactions; microbiome therapeutics; precision medicine

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Emerging Trends in Dental Caries: Insights into Etiology, Risk Factors, and Treatment Strategies (2nd Edition)

edited by

Hee-Eun Kim

submission deadline 28 Feb 2026 | Viewed by 133 | Submission Open

Keywords: antimicrobial effect; demineralization; dental caries; dental plaque; oral biofilm; oral disease; oral management; pathogenicity; prevention; remineralization

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Diagnostics in Diabetes: From Biomarkers to Clinical Applications

edited by

Robert Stawski

and Konrad Walczak

submission deadline 28 Feb 2026 | Viewed by 128 | Submission Open

Keywords: diabetes; molecular diagnostics; cell-free DNA (cfDNA); microRNAs; circulating biomarkers; diabetes complications; personalized therapy

(This special issue belongs to the Section Cell Biology and Pathology)

The Tumor Microenvironment and Heterogeneity: Challenges and Opportunities in Multiple Myeloma Immunotherapy

edited by

Enze Liu

submission deadline 28 Feb 2026 | Viewed by 126 | Submission Open

Keywords: multiple myeloma; immunotherapies; tumor microenvironment; novel targets; surfaceome; expression heterogeneity

(This special issue belongs to the Section Cancer Biology and Oncology)

Encephalitis and Viral Infection: Mechanisms and Therapies—2nd Edition

edited by Bradley S. Hollidge and

Samantha S. Soldan

submission deadline 28 Feb 2026 | Viewed by 123 | Submission Open

Keywords: neurovirology; encephalitis; gene therapy; viral vectors; virology; immunology; neuroscience; gene editing; neuroinflammation; arboviruses; innate immunity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Liver Cancer: Molecular and Translational Insights of Carcinogenesis and Treatments

edited by

Joon Hyuk Choi

submission deadline 28 Feb 2026 | Viewed by 118 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; intrahepatic cholangiocarcinoma; carcinogenesis; premalignant lesions; diagnosis; pathology; treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Thyroid Disease: From Mechanism to Therapeutic Approaches (2nd Edition)

edited by

Beata Wojtczak

submission deadline 28 Feb 2026 | Viewed by 117 | Submission Open

Keywords: pathogenesis and molecular mechanism of thyroid diseases; genetic disorders of the thyroid; biomarkers for thyroid dysfunctions; diagnostic challenges; new thyroid’ s therapies; immunotherapy; nuclear medicine; minimally invasive treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Generative Artificial Intelligence in Biomedical Sciences: Transforming Research, Diagnosis, and Therapy

edited by Iman Tavassoly

submission deadline 28 Feb 2026 | Viewed by 110 | Submission Open

Keywords: artificial intelligence; biomedical data; generative models; machine learning; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Channelopathies: Drug Interactions and Clinical Advances

edited by Cesar Celis Ceballos

submission deadline 28 Feb 2026 | Viewed by 105 | Submission Open

Keywords: electrophysiology; ion channels; channelopathies; drugs; patch-clamp

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Contribution of Neural Stemness and Its Regulatory Networks to Tumorigenesis

edited by

Ying Cao

submission deadline 28 Feb 2026 | Viewed by 104 | Submission Open

Keywords: neural stemness; tumorigenicity; pluripotency; phenotypic heterogeneity; cancer cell; cancer cell-intrinsic neural factors; differentiation therapy via targeting neural stemness; tumorigenesis; therapy resistance; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

Precision Approaches in the Diagnosis and Management of Inflammatory Bowel Disease

edited by

Jiayu Ye

submission deadline 28 Feb 2026 | Viewed by 99 | Submission Open

Keywords: inflammatory bowel disease; ulcerative colitis; Crohn’ s disease; precision medicine; microbiome-based therapy; noninvasive diagnostics; stratified therapeutic response; immunometabolism; system immunology; therapeutic repurposing

(This special issue belongs to the Section Cell Biology and Pathology)

State of the Art in Mitochondrial Research

edited by

Jan Ježek

submission deadline 28 Feb 2026 | Viewed by 97 | Submission Open

Keywords: mitochondrial metabolism; bioenergetics; mitochondrial signaling; mitochondrial dynamics; reactive oxygen species; apoptosis; hypoxia; mitochondrial genetics; mitochondrial diseases; aging

(This special issue belongs to the Section Cell Biology and Pathology)

Liquid Biopsy in Tumor

edited by Heidi Fettke

submission deadline 28 Feb 2026 | Viewed by 94 | Submission Open

Keywords: cfDNA; ctDNA; liquid biopsy; solid tumors; fragmentomics; MRD; cancer genomics; non-invasive biomarkers; treatment resistance; precision oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Metabolic Dysregulation in Chronic Kidney Disease: Emerging Mechanisms and Targeted Therapies

edited by

Leszek Niepolski

submission deadline 28 Feb 2026 | Viewed by 90 | Submission Open

Keywords: chronic kidney disease; metabolic dysregulation; biomarkers; gut-kidney axis; targeted therapy

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Molecular Mechanisms of Cardiovascular Diseases (CVDs)

edited by

Xiaoquan Rao

submission deadline 28 Feb 2026 | Viewed by 89 | Submission Open

Keywords: cardiovascular diseases (CVDs); molecular mechanisms; metabolic dysregulation; immunity; immunometabolism

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights in Immunological Pathways

edited by

Wan-Chung Hu

submission deadline 28 Feb 2026 | Viewed by 87 | Submission Open

Keywords: immune response; immune signal pathway; cytokine storm

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research in Cancer Immunotherapy

edited by

Sheila Spada

submission deadline 28 Feb 2026 | Viewed by 84 | Submission Open

Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology

(This special issue belongs to the Section Cancer Biology and Oncology)

Novel Biomarkers and Precision Medicine in Gynecologic Malignancies

edited by Zheng Feng

submission deadline 28 Feb 2026 | Viewed by 77 | Submission Open

Keywords: clinical trials; genomic landscape; targeted therapy; liquid biopsy; tumor screening; biomarker research; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

3D Cell Culture Systems for Biomedical Research, 2nd Edition

edited by

Agnieszka Rusak

and

Benita Wiatrak

submission deadline 28 Feb 2026 | Viewed by 74 | Submission Open

Keywords: 3D; scaffolds; spheroids; biomaterials; tumour model; bioengineering; tissue regeneration; regenerative medicine; targeted therapies; tissue mimics; angiogenesis; cancerogenesis; drug development; 3D printing; material functionalisation

(This special issue belongs to the Section Biomedical Engineering and Materials)

Molecular Mechanisms of Coronary Disease

edited by Quanyi Zhao and João P. Monteiro

submission deadline 28 Feb 2026 | Viewed by 73 | Submission Open

Keywords: atherosclerosis; coronary artery disease; cell fate transition; transcription; epigenetics; genetics; cytokine

(This special issue belongs to the Section Molecular and Translational Medicine)

Regenerative Medicine for Bone and Cartilage

edited by Deryk Jones

submission deadline 28 Feb 2026 | Viewed by 63 | Submission Open

Keywords: articular cartilage; bone marrow lesion; osteochondral allograft and autograft; chondrocyte; trabeculae; magnetic resonance image; regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Laser Applications in Medicine: Current Status and Emerging Challenges

edited by Irit Juwiler

submission deadline 16 Mar 2026 | 1 articles | Viewed by 924 | Submission Open

Keywords: lasers; medicine; surgery; dermatology; ophthalmology; dentistry; otolaryngology; gastroenterology; urology; gynecology; cardiology; neurosurgery; orthopedics; tissue types; biological interactions; technological advancements; clinical applications; health outcomes

(This special issue belongs to the Section Biomedical Engineering and Materials)

Biomarkers in Pain: 2nd Edition

edited by

Mats B. Eriksson

and

Anders O. Larsson

submission deadline 30 Mar 2026 | 2 articles | Viewed by 2015 | Submission Open

Keywords: analgesia; biomarker; CSF; cytokine; inflammation; neuropathy; neurotransmitter; pain; QoL; sensitization; sensory

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances in Chronic Rhinosinusitis and Asthma: 2nd Edition

edited by

Giuseppe Guida

and Cristiano Caruso

submission deadline 30 Mar 2026 | 1 articles | Viewed by 1701 | Submission Open

Keywords: asthma; chronic rhinosinusitis; nasal polyps; severe asthma; type-2 inflammation; phenotypes; endotypes; biologics; epithelial disfunction; remodeling

(This special issue belongs to the Section Molecular and Translational Medicine)

Metabolic Dysfunction-Associated Steatotic Disease

edited by Junzhao Ye

submission deadline 30 Mar 2026 | 1 articles | Viewed by 1039 | Submission Open

Keywords: metabolic dysfunction-associated fatty liver disease; metabolic dysfunction-associated steatotic disease; novel classification using proteomic and metabolomic profiles; new kinds of lifestyle modification interventions; especially for nutrition interventions; radiologic advances in steatosis; inflammation; and fibrosis assessments; artificial intelligence applications; therapeutic innovations; microbiota

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Exploring Acute Coronary Syndrome: Insights from Basic and Clinical Research—2nd Edition

edited by

Cristiana Bustea

submission deadline 30 Mar 2026 | 1 articles | Viewed by 826 | Submission Open

Keywords: acute coronary syndrome; cardiovascular morbidity; myocardial infarction; pathophysiology; diagnostic modalities; therapeutic interventions; translational research

(This special issue belongs to the Section Molecular and Translational Medicine)

Genetic and Epigenetic Research on Kidney Diseases

edited by Hailong Hu

submission deadline 30 Mar 2026 | Viewed by 105 | Submission Open

Keywords: kidney disease; genetics; epigenetics; DNA methylation; non-coding RNAs; precision medicine; therapeutic target; nephrology

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Displaying special issue 251-300 on page 6 of 16.

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