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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical, and Translational Neuropsychiatry—3rd Edition

edited by

Masaru Tanaka

and Simone Battaglia

submission deadline 30 Jun 2026 | Viewed by 97 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; psychiatric disorders; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive; behavioral; and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Novel Insights into Depression Research: Neurobiology, Models, Biomarkers and Therapies

edited by

Adela Magdalena Ciobanu

submission deadline 30 Jun 2026 | Viewed by 80 | Submission Open

Keywords: depression; neurobiology; biomarkers; experimental models; antidepressant therapies; personalized medicine; treatment resistance; pharmacology; psychiatric disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Thyroid Disorders: Comprehensive Insight from Functional Abnormalities, Structural Lesions to Autoimmunity

edited by

Darko Katalinić

submission deadline 30 Jun 2026 | Viewed by 77 | Submission Open

Keywords: thyroid gland pathology; autoimmunity; immunopathogenesis; diagnostic biomarkers; therapeutic strategies

(This special issue belongs to the Section Immunology and Immunotherapy)

Multiple Sclerosis: From Early Diagnosis to Personalized Treatment Strategies

edited by Alberto Calvi

submission deadline 30 Jun 2026 | Viewed by 76 | Submission Open

Keywords: multiple sclerosis; susceptibility; deformation-based techniques; PRL; GFAP; machine learning

(This special issue belongs to the Section Immunology and Immunotherapy)

Artificial Intelligence Applications in Neuroscience and Brain Diseases

edited by

Marios Krokidis

submission deadline 30 Jun 2026 | Viewed by 72 | Submission Open

Keywords: neuroscience; brain diseases; neurology and neurodegeneration; artificial intelligence; machine learning; bioinformatics; neuroimaging; neurotechnology; multimodal data integration; brain– computer interfaces; personalized medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Next-Generation Approaches in Clinical Antiviral Therapy: From Bench to Bedside

edited by

Pouya Hassandarvish

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: clinical antiviral therapy; antiviral potential; novel drug discovery platforms; host-targeted antivirals; drug repurposing; combination therapies; resistance mechanisms; clinical trial; viral infections; viral diseases

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Immunology in Recurrent Pregnancy Loss, Preeclampsia and Infertility

edited by

Jenny Valentina Garmendia

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: immunology of pregnancy; recurrent pregnancy loss; infertility; preeclampsia; autoimmunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Venous and Lymphatic Diseases: Updates on Phlebo-Lymphology and Cross-Talk

edited by

Sergiu-Ciprian Matei

and

Sergio Gianesini

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: chronic venous disease; chronic venous insufficiency; venous leg ulcers; venous reflux; vein wall; glycocalyx; lymphoedema; lipoedema

(This special issue belongs to the Section Molecular and Translational Medicine)

Targeted Nanomedicine: From Design to Application

edited by

Ming Ma

submission deadline 30 Jun 2026 | Viewed by 69 | Submission Open

Keywords: targeted nanomedicine; nanocarriers; nanosystems; drug delivery

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Hereditary Diseases: Insights from Genetic Perspectives

edited by

Maud de Dieuleveult

submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open

Keywords: genetic mutations; inheritance patterns; genomic medicine; monogenic disorders; genetic counseling

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Cardiac Arrhythmias: Technological Frontiers, Therapeutic Approaches and Future Directions

edited by

Panteleimon Pantelidis

Polychronis E. Dilaveris

, Raffaele De Lucia and

Evangelos Oikonomou

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: cardiac arrhythmias; electrophysiology; implantable devices; artificial intelligence; translational medicine; arrhythmogenesis; e-cardiology; biomarkers; telemonitoring

(This special issue belongs to the Section Molecular and Translational Medicine)

Update on Cancer Therapy

edited by

Jian Ruan

submission deadline 30 Jun 2026 | Viewed by 66 | Submission Open

Keywords: cancer; cancer immunotherapy; targeted therapy; ccancer vaccines; therapeutic agents; drug resistance mechanisms

(This special issue belongs to the Section Cancer Biology and Oncology)

Emerging Molecular and Translational Insights into Obstructive Sleep Apnea and Its Cardiovascular Comorbidities

edited by Hui-Ting Wang and

Yunglung Chen

submission deadline 30 Jun 2026 | Viewed by 64 | Submission Open

Keywords: obstructive sleep apnea (OSA); atrial fibrillation (AF); molecular mechanisms; epigenetics; biomarkers; oxidative stress; inflammation; endothelial dysfunction; translational research; precision medicine; artificial intelligence; cardiovascular comorbidities

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Precision Oncology in Solid Tumors: Emerging Biomarkers and Therapeutic Targets

edited by Giuseppe Nicolò Fanelli

submission deadline 30 Jun 2026 | Viewed by 63 | Submission Open

Keywords: precision oncology; predictive biomarkers; target therapy; molecular pathology; liquid biopsy; tumor microenvironment; immunotherapy; multi-omics integration; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis and Treatment of Amyotrophic Lateral Sclerosis (ALS)

edited by

Dongsheng Fan

submission deadline 30 Jun 2026 | Viewed by 63 | Submission Open

Keywords: amyotrophic lateral sclerosis (ALS); multi-target therapy; drug repurposing; translational research; biomarkers; induced pluripotent stem cells (iPSCs); clinical trial design; AI-based prediction models; precise treatment

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Lipid Nanoparticles for Cancer Immunotherapy

edited by Qiyan Wang

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: mRNA; LNP; cancer vaccine; immune therapy; target delivery

(This special issue belongs to the Section Immunology and Immunotherapy)

Pathogenesis, Diagnosis and Treatment of Infectious Diseases (2nd Edition)

edited by

Laura Franza

submission deadline 30 Jun 2026 | Viewed by 57 | Submission Open

Keywords: infection; infectious diseases; vaccination; antibiotics; antibiotic resistance; novel therapies; novel diagnosis; inflammaging; immunosenescence

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases (2nd Edition)

edited by Jixin Zhong

submission deadline 30 Jun 2026 | Viewed by 55 | Submission Open

Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies

(This special issue belongs to the Section Molecular and Translational Medicine)

Nano-Mediated Drug Delivery

edited by

Zhengxing Li

submission deadline 30 Jun 2026 | Viewed by 53 | Submission Open

Keywords: engineered nano-carriers; nanomedicine; micro/nanorobotics; targeted drug delivery; intelligent controllable systems; biohybrid systems; RNA therapeutics; translational nanotechnology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Role of DNA Methylation in Human Health and Diseases

edited by

Ting-Hai Xu

submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open

Keywords: DNA methylation; epigenetics; translational research; biomarker; gene regulation; epigenetic therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advanced Research in Melanoma Metastasis

edited by

Viktória Koroknai

submission deadline 30 Jun 2026 | Viewed by 50 | Submission Open

Keywords: melanoma; metastasis; tumor– host interactions; pre-metastatic niche; tumor microenvironment; organ-specific metastasis; molecular mechanisms; therapeutic targets

(This special issue belongs to the Section Cancer Biology and Oncology)

Nanomaterials for Drug Delivery: Current Status and Future Prospects

edited by

Bing Guo

and Madappa C. Maridevaru

submission deadline 30 Jun 2026 | Viewed by 50 | Submission Open

Keywords: nanomaterials for drug delivery; metal– organic frameworks (MOFs); porous nanomaterials; polymeric nanocarriers; inorganic nanoparticles; hybrid drug delivery systems; controlled drug release; targeted delivery; stimuli-responsive nanocarriers; biocompatible nanoplatforms; theranostics; precision nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Viral Hepatitis: From Pathophysiology to Therapeutic Approaches

edited by

Manish C. Choudhary

submission deadline 30 Jun 2026 | Viewed by 49 | Submission Open

Keywords: viral hepatitis; hepatotropic viruses; viral persistence; immunomodulatory; antiviral resistance

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Integrative Insights into Biology, Diagnosis and Treatment of Pulmonary Diseases

edited by

Te-Chun Shen

submission deadline 30 Jun 2026 | Viewed by 49 | Submission Open

Keywords: pulmonary medicine; critical care; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; lung cancer; respiratory infection; obstructive sleep apnea (OSA); respiratory failure; acute respiratory distress syndrome (ARDS)

(This special issue belongs to the Section Molecular and Translational Medicine)

Thrombophilia and Haemophilia: Pathophysiology and Therapeutic Interventions

edited by Petr Dulíček

submission deadline 30 Jun 2026 | Viewed by 49 | Submission Open

Keywords: hemophilia; therapy; thrombophilia; F XI inhibitors

(This special issue belongs to the Section Molecular and Translational Medicine)

Intraoperative Neurophysiology: New Perspectives and Clinical Applications

edited by Riccardo Budai and Giada Pauletto

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: IOM (intra operative monitoring); MEP (motor evoked potentials); SEP (somatosensory evoked potentials); BAEP (brainstem acoustic evoked potentials); VEP (visual evoked potentials); EMG (electromyography); EEG (electroencephalography); EcoG (electrocorticography); epilepsy; cerebral tumors

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advanced Research in Hematological Malignancies

edited by

Te-Fu Weng

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: hematological malignancies; leukemia; lymphoma; myeloma

(This special issue belongs to the Section Cancer Biology and Oncology)

Multiple Sclerosis: From Early Diagnosis to Personalized Therapeutic Approaches

edited by

Marta Ponzano

submission deadline 30 Jun 2026 | Viewed by 46 | Submission Open

Keywords: multiple sclerosis; diagnosis; revised criteria; neuroimaging; therapy; disability; individual well-being

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neonatal Disease: From Pathophysiology to Current and Emerging Therapeutic Approaches (3rd Edition)

edited by

Fumihiko Namba

submission deadline 30 Jun 2026 | Viewed by 45 | Submission Open

Keywords: fetal therapy; neonatal diseases; pathophysiology; innovative therapeutic approaches

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances of Biomedical Engineering and Materials

edited by Mei-Jung Chen,

Yaw Sing Tan

and

Chuan Li

submission deadline 30 Jun 2026 | Viewed by 45 | Submission Open

Keywords: tissue engineering; artificial intelligent biocompatible materials; cell therapy; drug delivery system

(This special issue belongs to the Section Biomedical Engineering and Materials)

Translational Immunology in Inflammatory Bowel Diseases: From Mechanisms to Precision Medicine

edited by Fotios S. Fousekis

submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open

Keywords: IBD; immunology; cytokine

(This special issue belongs to the Section Molecular and Translational Medicine)

Technologies and Applications of Genome Editing

edited by

Fu-Lei Tang

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: genome manipulation; CRISPR/Cas systems; preclinical animal models; translational research; editing efficiency; base editing and prime editing; genetically engineered mouse models (GEMMs); virus-like particles (VLPs)

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Genitourinary Cancers: From Molecular Pathogenesis to Precision Diagnosis and Therapy

edited by

Qi-Dong Xia

and Jian-Xuan Sun

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: genitourinary tumors; molecular pathogenesis; tumor microenvironment; biomarkers; liquid biopsy; immunotherapy; targeted therapy; therapy resistance; precision diagnosis

(This special issue belongs to the Section Cancer Biology and Oncology)

Integration of Multi-Omics Analysis and Biomaterial Innovation in Tissue Repair and Regeneration

edited by

Zhiwen Luo

submission deadline 30 Jun 2026 | Viewed by 43 | Submission Open

Keywords: biomaterial innovation; multi-omics integration; tissue engineering; regenerative medicine; personalized medicine; translational research

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in the Diagnosis and Treatment of Urothelial Cancers

edited by Aleksander Ślusarczyk and

Łukasz Zapała

submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open

Keywords: bladder cancer; urethral cancer; upper tract urothelial carcinoma

(This special issue belongs to the Section Cancer Biology and Oncology)

The Molecular Basis of Brain Diseases

edited by

Myung-Hoon Han

submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open

Keywords: molecular biomarkers; brain tumors; neurodegenerative diseases; gene regulation; immunotherapy; neuroinflammation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Mechanisms and Emerging Therapies in Human Skeletal Disorders

edited by Sudeep Gautam

submission deadline 30 Jun 2026 | Viewed by 41 | Submission Open

Keywords: skeletal disorders; genetic bone diseases; metabolic bone disease; rare skeletal dysplasias; extracellular matrix biology; CRISPR genome editing; genetically modified mouse models; gene therapy; AAV-based therapeutics; RNA therapeutics; musculoskeletal regeneration

(This special issue belongs to the Section Molecular and Translational Medicine)

Bowel Cancer: From Early Diagnosis to Personalized Treatment Strategies

edited by Maximos Frountzas

submission deadline 30 Jun 2026 | Viewed by 40 | Submission Open

Keywords: colorectal cancer; precision oncology; liquid biopsy; circulating tumor DNA (ctDNA); molecular biomarkers; radiomics and radiogenomics; artificial intelligence in oncology; tumor microenvironment; personalized therapy; early cancer detection

(This special issue belongs to the Section Cancer Biology and Oncology)

Decoding Retinal Degeneration

edited by

Enzo Maria Vingolo

submission deadline 30 Jun 2026 | Viewed by 40 | Submission Open

Keywords: retinal degeneration; inherited retinal diseases; retinitis pigmentosa; stargardt disease; age-related macular degeneration; photoreceptor degeneration; gene therapy; RNA-based therapies; epigenetic regulation; transcriptomics/proteomics; retinal biomarkers; molecular pathways of neurodegeneration; oxidative stress and inflammation; mitochondrial dysfunction; retinal microglia and neuroinflammation; retinal vasculopathy; stem cell therapy; retinal drug delivery; nanotechnology in ophthalmology; advanced retinal imaging (OCT; OCTA; FAF); artificial intelligence in retinal disease; precision and personalized ophthalmology; translational research in ophthalmology

(This special issue belongs to the Section Molecular and Translational Medicine)

Atopic Dermatitis in the Precision Medicine Era: Immunological Mechanisms, Biomarkers, and Therapeutic Innovations

edited by

Mihail Virgil Boldeanu

submission deadline 30 Jun 2026 | Viewed by 40 | Submission Open

Keywords: atopic dermatitis; immunopathology; skin barrier biology; neuroimmune signaling; microbiome interactions; therapeutic targets; biomarkers; personalized treatment approaches

(This special issue belongs to the Section Molecular and Translational Medicine)

Genomics and Epitranscriptomics Regulation in Cancer

edited by Ilias Georgakopoulos-Soares and

Candace S. Y. Chan

submission deadline 30 Jun 2026 | Viewed by 39 | Submission Open

Keywords: cancer genomics; epitranscriptomics; RNA modifications; non-coding RNAs; gene expression regulation; RNA splicing

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in the Pathogenesis and Therapeutics of Pulmonary Disease

edited by Sara Manti and

Paolo Ruggeri

submission deadline 30 Jun 2026 | Viewed by 38 | Submission Open

Keywords: pulmonary diseases; pathogenesis; therapeutic targets; drug discovery; respiratory inflammation; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in the Diagnosis and Management of Liver Cirrhosis and Portal Hypertension

edited by Xiaoze Wang

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: liver cirrhosis; portal hypertension; hepatic fibrosis; vascular remodeling; sinusoidal endothelial dysfunction; bile acid signaling; gut– liver axis; non-invasive diagnostics; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

Neurological Complications in Oncology: From Pathogenesis to Therapy

edited by Pierfranco Conte

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: neurological complications; neuro-oncology; neurotoxicity; chemotherapy-induced cognitive impairment; cancer-related neuropathy; neuroprotection; neuroimaging

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Burn Research: Therapeutic Innovations

edited by

Marcin Gierek

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: burn wound healing; regenerative medicine; tissue engineering; infection control in burns; scar prevention

(This special issue belongs to the Section Biomedical Engineering and Materials)

Metabolic Reprogramming and Immune Modulation in the Tumor Microenvironment: From Mechanisms to Immunotherapy Enhancement

edited by

Reza Bayat Mokhtari

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: cancer metabolism; tumor microenvironment; immune modulation; immunotherapy resistance; metabolic reprogramming; immunosuppression; combination therapy; biomarkers; metabolic plasticity; anti-tumor immunity

(This special issue belongs to the Section Cancer Biology and Oncology)

Drug Development in Gastrointestinal Disorders

edited by

Miglena Milusheva

and Stoaynka Atanasova Nikolova

submission deadline 30 Jun 2026 | Viewed by 33 | Submission Open

Keywords: inflammatory bowel disease (IBD); crohn's disease; gastrointestinal disorders; biologics; small-molecule inhibitors; drug delivery system; therapeutic target; drug resistance; biomarker; multitarget therapy; nanoparticles

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

New Advances in Heart Diseases

edited by

Patrick Dunn

submission deadline 30 Jun 2026 | Viewed by 31 | Submission Open

Keywords: biologics; heart diseases; regenerative medicine; gene therapy; stem cell therapy; monoclonal antibodies; RNA therapeutics; precision cardiology; cardiovascular regeneration; inflammatory modulation

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of Endothelial Cells in Human Health and Diseases

edited by Adama Sidibé

submission deadline 30 Jun 2026 | Viewed by 26 | Submission Open

Keywords: endothelial cells; angiocrine signaling; endothelial dysfunction; fibrosis; tumor microenvironment; cardiovascular disease; angiogenesis; vascular homeostasis; mechanotransduction; metabolic regulation

(This special issue belongs to the Section Cell Biology and Pathology)

Technology and Applications of Genome Editing in Biomedicine

edited by Guanhua Xun

submission deadline 30 Jun 2026 | Viewed by 9 | Submission Open

Keywords: RNA therapeutics; mRNA vaccines; antisense oligonucleotides (ASOs); siRNA and miRNA therapeutics; nucleic acid modifications; chemical stability and delivery; gene regulation therapy; precision medicine; CRISPR/Cas systems; guide RNA (gRNA); genome editing

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Displaying special issue 651-700 on page 14 of 16.

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