Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Progress in Cardiovascular Pharmacology submission deadline 31 Aug 2025 | 3 articles | Viewed by 4611 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Crohn’s Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition)
edited by and Junsik Sung
submission deadline 31 Aug 2025 | 6 articles | Viewed by 4011 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s  disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Bioactive Peptides and Derivatives as Therapeutic Agents: Potential Applications in Disease Treatment
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3951 | Submission Open
Keywords: bioactive peptide; peptide modification; application; cardiovascular disease; inflammatory disease; digestive disease; neurological disease; drug development
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Adiposity, Inflammation, and Metabolic Regulation: Molecular Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 3914 | Submission Open
Keywords: adipose tissue; inflammation; obesity and its metabolic complications; obesity pathogenesis
(This special issue belongs to the Section Molecular and Translational Medicine)
Connective Tissue Disorders: Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 31 Aug 2025 | 3 articles | Viewed by 3701 | Submission Open
Keywords: connective tissue disorders; pathophysiological mechanisms; inflammation; autoimmunity; extracellular matrix; fibrosis; biomarkers; treatment; therapeutic targets
(This special issue belongs to the Section Molecular and Translational Medicine)
MicroRNAs as Mediators of Tumor Cell State Transitions, Receptor Remodeling, Drug Resistance, and Systemic Metastasis
edited by and Michael J. Kerin
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3363 | Submission Open
Keywords: solid epithelial tumors; cancer stem cells; microRNAs; epigenetics; cell state transitions; chemoresistance; immunosuppression; tumor microenvironment; metastasis
(This special issue belongs to the Section Cancer Biology and Oncology)
Platelets in Health and Disease: From Molecular Mechanisms to Therapeutic Potential
edited by Henry Nording
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3261 | Submission Open
Keywords: platelet biology; vascular immunity; atherosclerosis; therapeutic targets; biomarkers
(This special issue belongs to the Section Cell Biology and Pathology)
Animal Models for the Study of Human Diseases
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2761 | Submission Open
Keywords: animal models; zebrafish; mice; rats
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Liquid Biopsy from Technological Innovation to Therapeutic Intervention
edited by and
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2747 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Meningioma: Novel Diagnostic and Therapeutic Approaches
edited by Carlen A. Yuen
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2361 | Submission Open
Keywords: meningioma; atypical; anaplastic; PET DOTATATE; octreotide; Lutetium-177; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research on Fibromyalgia (3rd Edition)
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2348 | Submission Open
Keywords: fibromyalgia; chronic fatigue syndrome; myofascial pain syndrome; diagnostic biomarkers; biomarkers for predicting treatment response; disability; rehabilitation; chronic pain; mutations and polymorphisms of genes related to fibromyalgia; epigenetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Drug Resistance and Tumor Microenvironment in Human Cancers
edited by , and Marília Isabel Neto Figueira
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2308 | Submission Open
Keywords: cancer therapy; drug resistance; tumor microenvironment; targeted therapy; precision medicine; cancer-related mechanisms
(This special issue belongs to the Section Cancer Biology and Oncology)
Lipids and Lipid Metabolism in Cardiovascular Health and Disease
edited by Fei Luo
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2157 | Submission Open
Keywords: lipids; lipoproteins; lipid metabolism; cardiovascular health and disease; atherosclerotic cardiovascular disease; lipid-lowering therapy; triglyceride-lowering therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Induced Pluripotent Stem Cells
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2131 | Submission Open
Keywords: induced pluripotent stem cells; organoids; tissue engineering; biomaterials; reprogramming; iPSC-based cell modelling; cell therapy; microfluidics; drug discovery
(This special issue belongs to the Section Gene and Cell Therapy)
Advances in Pediatric Ocular Pathology and Treatment
edited by Hyun-jin Shin
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2093 | Submission Open
Keywords: pediatric ophthalmology; eye diseases; genetics; medical; diagnostic techniques; ophthalmological; therapeutics
(This special issue belongs to the Section Cell Biology and Pathology)
Advanced Research on Skeletal Muscle Metabolism
edited by Lorenzo Sanesi
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2089 | Submission Open
Keywords: energy metabolism; mebabolic signaling pathways; homeostasis; myokines; aging; atrophy; muscle metabolism
(This special issue belongs to the Section Molecular and Translational Medicine)
Biotechnology in the Treatment and Management of Hearing Loss submission deadline 31 Aug 2025 | 1 articles | Viewed by 2006 | Submission Open
Keywords: hearing loss; gene therapy; regenerative medicine; cochlear implants; nanotechnology stem cell therapy; CRISPR-Cas9; auditory prosthetics; artificial intelligence; auditory regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advancements in Brain Diagnosis and Treatment: From Insights to Innovations
edited by Irene Chaves-Coira and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1983 | Submission Open
Keywords: brain diagnosis and treatment; underlying mechanisms; individualized treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in the Discovery of Novel Drugs on Natural Molecules, Second Edition submission deadline 31 Aug 2025 | 1 articles | Viewed by 1953 | Submission Open
Keywords: natural compounds; bioactive peptides; peptidomimetics; microbial metabolites; polyphenols; genome mining; molecular modeling; therapeutic uses
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Pathogenesis, Diagnosis and Treatment of Infectious Diseases
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1816 | Submission Open
Keywords: infection; infectious diseases; vaccination; antibiotics; antibiotic resistance; novel therapies; novel diagnosis; inflammaging; immunosenescence
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Polycystic Ovary Syndrome Research: From Molecular Mechanisms to Therapeutic Strategies—2nd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1816 | Submission Open
Keywords: female infertility; endocrine disorder; metabolic disorder; polycystic ovary syndrome; polycystic ovariany morphology; hyperandrogenism; menstrual irregularity; theraputicsTherapeutics; oxidative stress; antioxidant
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Microbial Infections and Sepsis: Pathophysiological Mechanisms and Therapeutic Approaches
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1752 | Submission Open
Keywords: sepsis; cytokines; inflammation; bacteria; stem cell; molecular biology; flow cytometry; multiplex; MALDI-TOF-MS; RT-PCR
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Emerging Trends in the Study of Inherited Metabolic Disorders
edited by Sudeep Gautam
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1700 | Submission Open
Keywords: inherited metabolic disorders; glycogen storage diseases; genetically modified mouse models; liver and kidney disease; hepatocellular carcinoma; autophagy; diabetes mellitus; patient-derived organoids; gene therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Mechanisms and Therapeutic Approaches for Hepatocellular Carcinoma
edited by Lanqi Gong, and Yu Zhang
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1576 | Submission Open
Keywords: hepatocellular carcinoma; HCC diagnosis and prognosis; HCC mechanisms; therapeutic resistance; immunotherapy; targeted therapy; personalized medicine; drug development; clinical trials; translational studies
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Cardiovascular Remodeling: Molecular Mechanisms and Therapeutic Targets
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1415 | Submission Open
Keywords: cardiac remodeling; vascular remodeling; ageing; pathogenesis; molecular mechanisms; diagnostics; therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Gliomas: Signaling Pathways, Molecular Mechanisms and Novel Therapies (2nd Edition)
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1261 | Submission Open
Keywords: glioma; molecular pathology; blood– brain barrier; immunotherapy; microenvironment; nanomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Immune Cell Biology: Insights from Molecular Perspectives
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1210 | Submission Open
Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Brain Imaging and Cognitive Deficits in Psychiatric Disorders, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1075 | Submission Open
Keywords: cognitive deficits; psychiatric disorders; schizophrenia; brain imaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Progress in Immunopharmacy
edited by and Shun-Hua Chen
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1019 | Submission Open
Keywords: immunopharmacy; immunopharmacology; immunomodulation; pharmacological intervention; immunotherapy; drug– immune system interaction; vaccine development; personalized pharmacotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
New Perspectives in the Treatment of Head and Neck Vascular Malformations
edited by Paolo Gennaro
submission deadline 31 Aug 2025 | 1 articles | Viewed by 893 | Submission Open
Keywords: vascular anomalies; vascular malformations; AVMs; venous malformations; electrosclerotherapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Biomedical Engineering for the Aging Population
edited by and Wen-Fong Wang
submission deadline 31 Aug 2025 | 1 articles | Viewed by 886 | Submission Open
Keywords: biomedical engineering; geriatric engineering; senescence; regenerative medicine; rehabilitation
(This special issue belongs to the Section Biomedical Engineering and Materials)
The Role of Immune Response in the Protection Against SARS-CoV-2 Infection
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 779 | Submission Open
Keywords: SARS-CoV-2; COVID-19; immune response; innate immune system; adaptative response; vaccines
(This special issue belongs to the Section Immunology and Immunotherapy)
Biomedicine in Dental and Oral Rehabilitation submission deadline 31 Aug 2025 | 1 articles | Viewed by 772 | Submission Open
Keywords: diagnosis; treatment; oral rehabilitation; dental and oral disease; biomedicine; biomaterial; regeneration; functional; esthetics
(This special issue belongs to the Section Biomedical Engineering and Materials)
Multiple Sclerosis: Diagnosis and Treatment—3rd Edition
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 743 | Submission Open
Keywords: multiple sclerosis; pathogenesis; progressive MS; MRI; disease-modifying therapies; demyelinating disorders; cognitive dysfunction; intestinal microbiota
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Osteoarthritis: Molecular Pathways and Novel Therapeutic Strategies—2nd Edition
edited by , , and Andrea Pantalone
submission deadline 31 Aug 2025 | 1 articles | Viewed by 726 | Submission Open
Keywords: osteoarthritis; cartilage; pain; orthopedics; rehabilitation
(This special issue belongs to the Section Molecular and Translational Medicine)
Imaging Technology for Human Diseases
edited by Emanuele David
submission deadline 31 Aug 2025 | 1 articles | Viewed by 680 | Submission Open
Keywords: technological advances; imaging; X-ray; mammography; CT; MRI; ultrasound; angiography
(This special issue belongs to the Section Biomedical Engineering and Materials)
Emerging Insights in Thoracic Diseases: From Diagnostics to Biomarkers and Therapeutic Implications Through Interdisciplinarity submission deadline 31 Aug 2025 | 1 articles | Viewed by 589 | Submission Open
Keywords: chronic obstructive pulmonary disease; acute respiratory diseases; cardionephrology; interstitial lung disease; interventional cardiology; pulmonary fibrosis; tuberculosis; research methodology; biomarkers; therapeutics; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
Progress in Cytotoxicity of Biomaterials
edited by Lakkamraju Vijayalakshmi
submission deadline 31 Aug 2025 | 1 articles | Viewed by 514 | Submission Open
Keywords: biomaterial cytotoxicity; biocompatibility assessment; in vitro and in vivo toxicity; surface modification; nanomaterials in medicine; oxidative stress and inflammation; tissue engineering materials; drug delivery systems; biodegradable polymers; regulatory perspectives on biomaterial safety
(This special issue belongs to the Section Biomedical Engineering and Materials)
Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes—2nd Edition
edited by
submission deadline 31 Aug 2025 | Viewed by 497 | Submission Open
Keywords: type 2 diabetes; hypertension; LDL-cholesterol; serum lipids; metabolic syndrome; cardiovascular disease; chronic complications; nephropathy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Feature Reviews in Target Identification and Drug Discovery
edited by
submission deadline 31 Aug 2025 | Viewed by 464 | Submission Open
Keywords: drug discovery; biological target; bioactive compounds; pharmacology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Peptide Therapeutic Approaches for Cancer Treatment submission deadline 31 Aug 2025 | Viewed by 395 | Submission Open
Keywords: peptide therapeutics; cancer treatment; drug delivery systems; molecular imaging; bioinformatics; machine learning and artificial intelligence (AI); therapeutic targeting; peptide– drug conjugates; personalized medicine; immunotherapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advancements in the Treatment of Mesothelioma
edited by
submission deadline 31 Aug 2025 | Viewed by 352 | Submission Open
Keywords: mesothelioma; targeted therapy; diagnostics; checkpoint inhibitors; immunotherapy; chemotherapy; combination therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Antiviral Innate Immunity
edited by Junji Zhu
submission deadline 31 Aug 2025 | Viewed by 333 | Submission Open
Keywords: antiviral immunity; innate immune signaling; toll-like receptors (TLRs); RIG-I-like receptors (RLRs); cGAS-STING pathway; type I interferon; viral infection; post-translational modification (PTM); phase separation; host– pathogen interactions; therapeutic strategies
(This special issue belongs to the Section Microbiology in Human Health and Disease)
New Trends in Regional Anesthesia and Pain Management
edited by
submission deadline 31 Aug 2025 | Viewed by 306 | Submission Open
Keywords: regional anesthesia; ultrasound-guided/stimulator-guided nerve blocks; novel techniques for motor-sparing neural intervention; continuous catheter infusions; opioid-sparing techniques; perioperative pain management; novel local anesthetics; cadaveric dissection exploring the anatomical knowledge of motor-sparing techniques; modalities (techniques; technologies; or drug regimen) to prolong the effect of local anesthetics; ERAS-related studies; AI applications in regional anesthesia and pain management; innovations and protocols/curriculum regarding regional anesthesia and pain management in the battlefield; studies comparing new technologies/simulation (such as EpiFaith; SPRint PNS system; or CompuFlo) with traditional methods in improving regional anesthesia and pain management; regenerative medicine; nutritional pain medicine; application of bone marrow aspirate concentration or other stem cell components in pain medicine; multidisciplinary/comprehensive care program; transarterial embolization for pain management; joint denervation for pain management
(This special issue belongs to the Section Molecular and Translational Medicine)
Respiratory Allergies: Insights from Molecular Perspectives
edited by Sara Manti and
submission deadline 31 Aug 2025 | Viewed by 302 | Submission Open
Keywords: pediatrics; allergology; pulmounology; acute and chronic respiratory diseases; congenital and acquired respiratory diseases; novel treatment.
(This special issue belongs to the Section Immunology and Immunotherapy)
Recent Advances in Adipokines (3nd Edition)
edited by
submission deadline 31 Aug 2025 | Viewed by 301 | Submission Open
Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Mitochondrial Dysfunction and Reactive Oxygen Species in Aging and Related Diseases
edited by and Gohar Azhar
submission deadline 31 Aug 2025 | Viewed by 301 | Submission Open
Keywords: mitochondrial dysfunction; aging; reactive oxygen species; mitochondrial dynamics; mitophagy; mitochondrial biogenesis; age-related disorders
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
The Role of Environmental Pollutants in Cancer and Chemoresistance submission deadline 31 Aug 2025 | Viewed by 292 | Submission Open
Keywords: environmental pollutants; cancer cells; therapeutic agents
(This special issue belongs to the Section Cancer Biology and Oncology)
Roles of Extracellular Vesicles in Cancer Immunotherapy
edited by Shujing Liu and Zhiyuan Qin
submission deadline 31 Aug 2025 | Viewed by 274 | Submission Open
Keywords: extracellular vesicles; microvesicles; exosomes; cancer biology; cancer immunity; cancer immunotherapy; biomarkers; cancer vaccines; antigen presentation; drug delivery
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of Cytokines in Health and Disease: 3rd Edition
edited by
submission deadline 31 Aug 2025 | Viewed by 252 | Submission Open
Keywords: cytokine; chemokine; neurodegenerative disease; cancer; inflammatory mediator; diagnosis; biomarker
(This special issue belongs to the Section Cell Biology and Pathology)
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