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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microbial Communities: Interactions, Evolution, and Function

edited by Krisztina Nagy, Peter Galajda and Juan E. Keymer

submission deadline 30 Apr 2027 | 1 articles | Viewed by 853 | Submission Open

Keywords: microbial communities; microbial interactions; microbial communication; spatial organization; biofilm formation; evolution

(This special issue belongs to the Section Ecology)

Advances in Cell Division and Chromosome Segregation Mechanisms

edited by

Zhixin (Jason) Lyu

submission deadline 30 Apr 2027 | Viewed by 526 | Submission Open

Keywords: cell division; chromosome segregation; bacterial cell biology; mammalian cell cycle; genome stability; cytoskeletal dynamics; structural biology; advanced imaging

(This special issue belongs to the Section Cell Biology)

Advances in Embryo Biotechnology and Stem Cell Applications for Animal Conservation and Production

edited by

Rangsun Parnpai

and Ampika Thongphakdee

submission deadline 30 Apr 2027 | Viewed by 257 | Submission Open

Keywords: gametes; embryos; IVP; iPSCs; IVG; cryopreservation; livestock; endangered species; production; conservation

(This special issue belongs to the Section Developmental and Reproductive Biology)

Underrepresented Pathogens: Evolution, Adaptation, and Biological Mechanisms Across Kingdoms

edited by

Dan-Alexandru Țoc

and Ioana Alina Colosi

submission deadline 30 Apr 2027 | Viewed by 232 | Submission Open

Keywords: underrepresented; emerging pathogens; microbial adaptation; evolution and pathogenicity; genome plasticity; host–pathogen interaction; experimental evolution; ecological transitions

(This special issue belongs to the Section Microbiology)

Investigating Reproductive System Diseases Through Animal Models

edited by Diogo Benchimol de Souza

submission deadline 30 Apr 2027 | Viewed by 222 | Submission Open

Keywords: reproductive diseases; animal models; infertility; spermatogenesis; ovarian function; endocrine regulation; reproductive toxicology; translational research; experimental pathology; molecular mechanisms

(This special issue belongs to the Section Developmental and Reproductive Biology)

Plant Responses to Biostimulants and Abiotic Stress

edited by

Stefano Loppi

and

Riccardo Fedeli

submission deadline 30 Apr 2027 | Viewed by 203 | Submission Open

Keywords: biostimulants; abiotic stress; wood vinegar; biochar; plant stress tolerance; sustainable agriculture; crop resilience

(This special issue belongs to the Section Plant Science)

Ecology, Conservation Physiology and Population Monitoring of Endangered Animals

edited by

Hao Du

Chenhong Li

and

Peilin Cheng

submission deadline 30 Apr 2027 | Viewed by 134 | Submission Open

Keywords: endangered aquatic animals; conservation physiology; population monitoring; environmental stressors; adaptative mechanisms; innovative technologies

(This special issue belongs to the Section Marine and Freshwater Biology)

Biodiversity, Integrative Taxonomy, Molecular Approaches, Systematics, and Biogeography of Fishes

edited by

Felipe Ottoni

and Elisabeth Henschel

submission deadline 30 Apr 2027 | Viewed by 116 | Submission Open

Keywords: DNA-barcoding; environmental DNA; evolution; phylogenetics; ichthyology; species delimitation methods; species description; species distribution

(This special issue belongs to the Section Marine and Freshwater Biology)

Internal Defense System and Evolution of Aquatic Animals

edited by

Alessio Alesci

submission deadline 15 May 2027 | 10 articles | Viewed by 24306 | Submission Open

Keywords: internal defense system; evolution; aquatic animals; immunology; aquatic environment; biodiversity; pollution; ecosystems

(This special issue belongs to the Section Evolutionary Biology)

Genetic and Genomic Insights into Cardiovascular Disease

edited by Silvio Zaina and

Carol C. Shoulders

submission deadline 15 May 2027 | 1 articles | Viewed by 822 | Submission Open

Keywords: coronary and carotid atheroma; lipids; thrombosis; inflammation; vascular calcification; vascular smooth muscle cells; foam cells; endothelium; immune cells; epigenetics; genetic variation; gene expression and proteomics; cell and disease models

(This special issue belongs to the Section Genetics and Genomics)

Environmental and Lifestyle Drivers of Redox Imbalance: Mechanisms, Biomarkers and Therapeutic Opportunities

edited by Natalia Kurhaluk and Halina Tkaczenko

submission deadline 30 May 2027 | Viewed by 247 | Submission Open

Keywords: redox homeostasis and oxidative stress regulation; environmental toxicants and redox imbalance; dietary antioxidants and bioactive food compounds; gut microbiota–redox interactions; physical activity and ROS‑mediated hormesis; mitochondrial dysfunction and redox‑targeted therapies; redox biomarkers for diagnosis and monitoring

(This special issue belongs to the Section Cell Biology)

Aquatic Animal Nutrition and Feed

edited by

Yun Wang

submission deadline 31 May 2027 | 12 articles | Viewed by 26433 | Submission Open

Keywords: aquaculture; aquatic animals; nutrition; aquatic feed; immunity; metabolism

Head and Neck Cancer: Current Advances and Future Perspectives

edited by Ana Jotic

submission deadline 31 May 2027 | 5 articles | Viewed by 6379 | Submission Open

Keywords: head and neck cancer; tumor microenvironment; genetic and epigenetic alterations; oncogenes and tumor suppressor genes; signal transduction pathways; immune evasion; metastasis; drug resistance mechanisms; molecular etiology; cancer biology

(This special issue belongs to the Section Cancer Biology)

Studies on Insect Genetics and Genomics

edited by Ying Lin

submission deadline 31 May 2027 | 5 articles | Viewed by 4084 | Submission Open

Keywords: novel sequencing technologies; genome-editing methods; sex chromosome origins; horizontal gene transfer; resource insects; eco-friendly insect control technologies; genomics; ecology; molecular biology; insect

(This special issue belongs to the Section Genetics and Genomics)

Heavy Metal Pollution and Bioremediation: Application and Mechanism

edited by

Guangxu Zhu

, Ruiyu Lin and Rongfei Wei

submission deadline 31 May 2027 | 3 articles | Viewed by 4075 | Submission Open

Keywords: heavy metal pollutants; microbial remediation; phytoremediation; animal remediation; plant–soil–microbe interactions; enhanced remediation; combined remediation; hyperaccumulator plants; microbial-induced calcium carbonate precipitation

(This special issue belongs to the Section Toxicology)

Recent Advances in Biological Research on Prostate Cancer

edited by Samson Mashele and Pakiso Makhoahle

submission deadline 31 May 2027 | 1 articles | Viewed by 3512 | Submission Open

Keywords: prostate cancer; biological research; molecular mechanisms; biomarkers; precision medicine; therapeutic targets; tumor microenvironment; therapeutic resistance; genomics; quality of life

(This special issue belongs to the Section Cancer Biology)

Physiology and Pathophysiology of Skin (2nd Edition)

edited by Seon-Pil Jin

submission deadline 31 May 2027 | 1 articles | Viewed by 1423 | Submission Open

Keywords: epidermal barrier; melanogenesis; wound healing; skin immunity; sensory perception; dermatitis; psoriasis; atopic dermatitis; autoimmune skin disorders; therapeutic approaches

(This special issue belongs to the Section Physiology)

Understanding and Targeting Biological Mechanisms of Heart Failure (2nd Edition)

edited by

Lei Ye

and

Wuqiang Zhu

submission deadline 31 May 2027 | Viewed by 1250 | Submission Open

Keywords: developmental biology; genetics; stem cells; heart failure; cell therapy

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Pluripotent Stem Cells in Development and Disease

edited by

Qiang Wu

submission deadline 31 May 2027 | 1 articles | Viewed by 1185 | Submission Open

Keywords: pluripotent stem cells (PSCs); early development; regenerative medicine; genetic/epigenetic factors; differentiation; cell fate determination; disease modelling; organoids; genomic editing; single-cell omics

(This special issue belongs to the Section Developmental and Reproductive Biology)

Drosophila melanogaster: Cutting-Edge Applications in Medicine and Pharmacy

edited by

Yiwen Wang

submission deadline 31 May 2027 | 1 articles | Viewed by 752 | Submission Open

Keywords: Drosophila melanogaster; disease model; drug development; therapeutic target; metabolic disease; cancer; neurodegeneration diseases; cardiovascular disease; pathogenesis; pharmacology

(This special issue belongs to the Section Medical Biology)

Exploring the Role of Serotonin in Psychiatric Disorders

edited by

Georgianna Gould

submission deadline 31 May 2027 | Viewed by 628 | Submission Open

Keywords: diet; drug treatments; enzymes; epigenetic; post translational modification; serotonin metabolism; serotonin receptors; serotonin transporters

(This special issue belongs to the Section Neuroscience)

Plant Phenology and Climate Change: Patterns, Responses, and Variability

edited by

Zhi Ding

Fengqin Yan

and

Qi Wang

submission deadline 31 May 2027 | 1 articles | Viewed by 532 | Submission Open

Keywords: plant phenology; climate change; remote sensing; big data; extreme climate events; ecosystem services; coastal wetlands; ecologically fragile regions

(This special issue belongs to the Section Plant Science)

CRISPR-Engineered Mouse Models for Unraveling Rare Diseases

edited by

Manuel A. Sanchez-Martin

submission deadline 31 May 2027 | Viewed by 472 | Submission Open

Keywords: mouse models; CRISPR/Cas9; rare disease modeling; phenotyping; translational research; svatar mice

(This special issue belongs to the Section Medical Biology)

From GWAS to Mechanism: Genetic Insights into Autoimmune Disease Pathophysiology

edited by Mohsen Khosravi-Maharlooei

submission deadline 31 May 2027 | Viewed by 253 | Submission Open

Keywords: GWAS; autoimmune disease; genetic susceptibility; HLA; functional genomics; single-cell sequencing; epigenomics; immune tolerance; antigen presentation; precision medicine

(This special issue belongs to the Section Physiology)

Advances in Nutritional Biochemistry and Physiology

edited by

Lawrence Mabasa

submission deadline 31 May 2027 | Viewed by 218 | Submission Open

Keywords: nutrition; metabolism; bioactive compounds; gut microbiota; oxidative stress; inflammation; nutrient sensing; micronutrients; dietary regulation; metabolic pathways; animal model; cells

(This special issue belongs to the Section Physiology)

Silk, Honey, and Venom Gene Functions: Research and Applications of Non-Drosophila Resource Insects

edited by

Guanwang Shen

submission deadline 31 May 2027 | Viewed by 166 | Submission Open

Keywords: resource insects; Bombyx mori; Vespula vulgaris; gene function; metabolism; artificial rearing; biomedical applications

(This special issue belongs to the Section Zoology)

Bioinformatics Within Precision Oncology

edited by

Jorge Melendez-Zajgla

submission deadline 31 May 2027 | Viewed by 58 | Submission Open

Keywords: bioinformatics; precision oncology; cancer genomics; multi-omics; machine learning; tumor heterogeneity; variant interpretation; cancer biology; systems biology; computational oncology

(This special issue belongs to the Section Cancer Biology)

Plasticity in the Autonomic Nervous System

edited by

Miguel Angel Morales

submission deadline 3 Jun 2027 | 1 articles | Viewed by 2173 | Submission Open

Keywords: autonomic nervous system; synaptic plasticity; neuroplasticity; neurotransmitters; co-transmission; long-term potentiation; sympathetic nervous system; parasympathetic nervous system; heart; dysautonomia; heart failure

(This special issue belongs to the Section Neuroscience)

From Basics to Applications of Gene Regulatory Networks

edited by

Thomas Ulas

submission deadline 15 Jun 2027 | 4 articles | Viewed by 12485 | Submission Open

Keywords: gene regulatory networks; computational methods; modeling and simulation; disease mechanisms; therapeutic targeting; transcriptomics

(This special issue belongs to the Section Genetics and Genomics)

Advances in Infection and Genetic Diversity of Zoonotic Parasites, Hosts and Vectors

edited by

Weerachai Saijuntha

submission deadline 30 Jun 2027 | 3 articles | Viewed by 8207 | Submission Open

Keywords: zoonotic parasites; prevalence of infection; helminths; protozoa; vectors; genetic diversity; zoonoses; hosts

(This special issue belongs to the Section Infection Biology)

Research Advances in Aquatic Omics

edited by

Zhengyong Wen

Qiong Shi

and Haiping Liu

submission deadline 30 Jun 2027 | 6 articles | Viewed by 7391 | Submission Open

Keywords: aquatic animals; genomics; transcriptomics; proteomics; metabolomics; genetics; evolutionary biology

(This special issue belongs to the Section Evolutionary Biology)

Advances in Biological Breast Cancer Research (2nd Edition)

edited by

Anna-Mart Engelbrecht

Joji Mercier

and

Iman Van Den Bout

submission deadline 30 Jun 2027 | 5 articles | Viewed by 7171 | Submission Open

Keywords: breast cancer; breast tumor; breast cancer cells; animal models; cell death; cancer diagnosis; cancer treatment; biomarkers; cancer microenvironment; carcinogens; estrogen receptor; molecular biology; cell biology

(This special issue belongs to the Section Cancer Biology)

Mitochondrial Genomics of Arthropods

edited by Renfu Shao

submission deadline 30 Jun 2027 | 8 articles | Viewed by 6251 | Submission Open

Keywords: mitochondrial genome architecture; transcriptional dynamics; translational mechanisms; comparative genomics; molecular evolution; arthropod phylogenetics; systematics; evolutionary biology

(This special issue belongs to the Section Genetics and Genomics)

Metals in Biology (2nd Edition)

edited by

Muhamed Amin

submission deadline 30 Jun 2027 | 4 articles | Viewed by 6222 | Submission Open

Keywords: metalloenzymes; iron sulfur cluster; mn cluster; photosystem I; photosystem II

Paper Collection: Understanding Immune Systems

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 30 Jun 2027 | 3 articles | Viewed by 4628 | Submission Open

Keywords: immune mechanisms; evolutionary immunology; comparative immunology; innate immunity; adaptive immunity; autoimmunity; chronic inflammation; immune ageing; host–pathogen interactions; vaccinology; regenerative medicine

(This special issue belongs to the Section Immunology)

Latest Research in Cancer Multi-Omics

edited by Philip Anthony Sutera

submission deadline 30 Jun 2027 | 2 articles | Viewed by 4174 | Submission Open

Keywords: cancer; multi-omics; genomics; transcriptomics; proteomics; metabolomics; radiomics; pathomics; precision medicine; artificial intelligence

(This special issue belongs to the Section Bioinformatics)

Exploring the Impact of Probiotics and Fermented Food on Gut Microbiota for Personalized Nutrition and Host Health

edited by

Massalin Nakphaichit

and

Suvimol Charoensiddhi

submission deadline 30 Jun 2027 | 3 articles | Viewed by 3336 | Submission Open

Keywords: probiotics (bacteria and yeast); gut microbiota and mycobiome; personalized nutrition; microbiome–host interaction mechanisms; gut–axis communication (brain/skin/immune)

(This special issue belongs to the Section Microbiology)

Biology, Ecology and Management of Invasive Alien Plants (2nd Edition)

edited by

Guoqi Chen

and

Jiang Wang

submission deadline 30 Jun 2027 | 2 articles | Viewed by 2690 | Submission Open

Keywords: changes in the composition and distribution of alien plants; invasive mechanisms; invasiveness; invasibility; invasive population; invasive plant interactions with other organisms; impacts on environment, ecosystem services and human health; chemical control; management of invasive plants; utilization of invasive plants

(This special issue belongs to the Section Plant Science)

Biosynthesis and Regulation of Plant Tissue-Specific Metabolites

edited by

Xiumin Fu

submission deadline 30 Jun 2027 | 3 articles | Viewed by 1680 | Submission Open

Keywords: underground tissue metabolites; root; root exudates; genetic regulation; rhizosphere microbial interaction; environmental response

(This special issue belongs to the Section Plant Science)

Interactions Between Membrane Proteins and Membrane Lipids

edited by

Youzhong Guo

submission deadline 30 Jun 2027 | 1 articles | Viewed by 1601 | Submission Open

Keywords: membrane protein; lipid bilayer; enzyme; channel; receptor; transporter; cryo-EM; X-ray crystallography; structural biology; drug target

(This special issue belongs to the Section Biophysics)

Perception in Noise: From Human Perceptive Abilities to Neural Correlates and Computational Models

edited by

Jean Marc Edeline

submission deadline 30 Jun 2027 | 1 articles | Viewed by 1539 | Submission Open

Keywords: auditory perception; neural networks; communication sounds; auditory system; masking noise; coding in noise; robust representation

(This special issue belongs to the Section Neuroscience)

Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services—3rd Edition

edited by

Giorgio Mancinelli

Paraskevi K. Karachle

Elena Tricarico

and

Baran Yoğurtçuoğlu

submission deadline 30 Jun 2027 | 1 articles | Viewed by 1267 | Submission Open

Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation

(This special issue belongs to the Section Marine and Freshwater Biology)

Environmental and Hormonal Modulators of Cell Fate: Epigenetic and Phenotypic Plasticity in Somatic Tissues

edited by Alireza R. Fazeli and

Małgorzata Duda

submission deadline 30 Jun 2027 | 1 articles | Viewed by 1137 | Submission Open

Keywords: cell fate; epigenetic regulation; phenotypic plasticity; hormonal signaling; environmental stressors; endocrine disruptors; somatic tissues; senescence; reprogramming; non-coding

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Breaking Barriers in Metabolic Health: Novel Insights into Obesity and Metabolic Disorders

edited by Aijun Qiao

submission deadline 30 Jun 2027 | 1 articles | Viewed by 1087 | Submission Open

Keywords: metabolic disorders; pathogenesis and mechanisms; biomarkers

(This special issue belongs to the Section Medical Biology)

From Morphology to Molecules: Traditional Bioassessment, eDNA and eRNA Monitoring in a Changing World

edited by

Shuping Wang

, Xiaofeng Cao and Zhenjun Tian

submission deadline 30 Jun 2027 | 2 articles | Viewed by 913 | Submission Open

Keywords: environmental DNA; environmental RNA; biotic indices; biomonitoring; ecosystem health assessment; morphological identification; molecular detection; multi-taxa biomonitoring; microbes to macrobes; data integration

(This special issue belongs to the Section Ecology)

Applications of Yeast Biotechnology

edited by

Pornthap Thanonkeo

submission deadline 30 Jun 2027 | 1 articles | Viewed by 823 | Submission Open

Keywords: biofuel and feed production; biological control; waste treatment and utilization; yeast metabolites; enzyme technology; yeast strain development; process development

(This special issue belongs to the Section Biotechnology)

Applications of Gene Expression Profiling in Human Disease

edited by

Lipei Shao

submission deadline 30 Jun 2027 | 1 articles | Viewed by 795 | Submission Open

Keywords: gene expression profile; biomarkers; cancer; complex disease

(This special issue belongs to the Section Genetics and Genomics)

Artificial Intelligence Research for Complex Biological Systems (2nd Edition)

edited by

Yong Chen

and

Milana Frenkel-Morgenstern

submission deadline 30 Jun 2027 | 1 articles | Viewed by 550 | Submission Open

Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics

(This special issue belongs to the Section Bioinformatics)

Genetic Breeding and Reproduction of Aquatic Animals—2nd Edition

edited by

Huaping Zhu

, Dongmei Ma and

Zaixuan Zhong

submission deadline 30 Jun 2027 | Viewed by 509 | Submission Open

Keywords: genetic breeding; reproduction technology; gene; protein; molecular marker; trait; QTLs; molecular marker; fish; shrimp; crab; shellfish; aquatic animals; transcriptomics; proteomics; metabonomics

(This special issue belongs to the Section Zoology)

Cytochrome P450s Across Biological Systems: From Molecular Mechanisms to Biotechnological and Biomedical Applications

edited by

Pradeepraj Durairaj

submission deadline 30 Jun 2027 | Viewed by 394 | Submission Open

Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; biocatalysis and biotransformation; orphan enzymes; redox biology; structural biology; synthetic biology; enzyme engineering; multi-omics approaches

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Displaying special issue 251-300 on page 6 of 8.

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