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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gut Microbiome in Health and Disease (2nd Edition)

edited by

Hao Zhong

and

Fengqin Feng

submission deadline 15 Jul 2025 | 14 articles | Viewed by 23480 | Submission Open

Keywords: gut microbiota; ‘ gut-x’ axis; dysbiosis; food nutrition; metabolites; type 2 diabetes mellitus; gut health; immunity

(This special issue belongs to the Section Microbiology)

The Evolving Trends of Freshwater Microbial Communities Under the Influence of Climate Change and Anthropogenic Pollution

edited by Yantian Ma

submission deadline 15 Jul 2025 | Viewed by 272 | Submission Open

Keywords: freshwater microorganisms; community structure and function; microbial metabolic pathways/potentials; functional genes and genomes; water contaminants and restoration; microbial community ecology and bio-indicators

(This special issue belongs to the Section Microbiology)

Tissue and Organ Regeneration in Fish: Evolutionary Mechanisms

edited by Yujun Liang

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2199 | Submission Open

Keywords: organ and tissue regeneration; regeneration mechanisms; progenitor cells; dedifferentiation; fishes; evolutionary adaptation; genetic regulation; signaling pathways; comparative genomics

(This special issue belongs to the Section Evolutionary Biology)

Alien Marine Species in the Mediterranean Sea

edited by

Claudia Cosentino

submission deadline 31 Jul 2025 | 6 articles | Viewed by 16409 | Submission Open

Keywords: marine organisms; ecology and paleoecology; biodiversity; Mediterranean ecosystem

(This special issue belongs to the Section Marine Biology)

Novel Insights of Bone Repair: Strategies for Improvement, Microscopic, Molecular and Ultrastrastructural Aspects

edited by

Roberta Okamoto

, Kathryn Grandfield and Karina Carneiro

submission deadline 31 Jul 2025 | 10 articles | Viewed by 15216 | Submission Open

Keywords: bone repair; aging; bone remodeling; biomaterials; drug delivery; bone regeneration

Advances in Wildlife Conservation and Habitat Management in the Anthropocene

edited by

Yiannis G. Zevgolis

and

Panayiotis G. Dimitrakopoulos

submission deadline 31 Jul 2025 | 10 articles | Viewed by 14861 | Submission Open

Keywords: innovative technologies; advanced monitoring techniques; habitat suitability modeling; species distribution modeling; climate change scenarios; anthropogenic; biotic; and abiotic stressors; environmental impact assessments; invasive species management; disease outbreak impacts; long-term ecological monitoring; protected area effectiveness; keystone species conservation; threatened species; adaptive conservation strategies; conservation planning; wildlife conservation; habitat management

(This special issue belongs to the Section Ecology)

Plant Natural Products: Mechanisms of Action for Promoting Health

edited by

Francisco Les

and

Guillermo Cásedas

submission deadline 31 Jul 2025 | 9 articles | Viewed by 11777 | Submission Open

Keywords: phytochemicals; bioactivity; therapeutics; mechanisms; health promotion; metabolism; enzyme activity; bioactive compounds; pharmacognosy; plant extracts; polyphenols; ethnopharmacology; essential oils; aromatic plants; antioxidants; natural products

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Dendrochronology in Arid and Semiarid Regions

edited by

Zongshan Li

submission deadline 31 Jul 2025 | 6 articles | Viewed by 11244 | Submission Open

Keywords: tree rings; growth– climate response; dendrochronology; dendroecology; dryland regions

(This special issue belongs to the Section Ecology)

Advances in Biological Research of Adipose-Derived Stem Cells

edited by Xinlin Yang

submission deadline 31 Jul 2025 | 4 articles | Viewed by 11053 | Submission Open

Keywords: adipose-derived stem cells (ADSCs); isolation and culture method; biomarkers and multipotency; immunomodulation; regenerative medicine; tissue engineering

(This special issue belongs to the Section Cell Biology)

Host–Pathogen Interactions and Pathogenesis

edited by

Sashi Kant

, Deeksha Tripathi and Saurabh Pandey

submission deadline 31 Jul 2025 | 4 articles | Viewed by 7917 | Submission Open

Keywords: host-pathogen dynamics; infectious disease mechanisms; virulence factors; microbial interactions; pathogenicity; emerging pathogens; immunological response; immunomodulation tactics; infection prevention; disease pathophysiology

Aquatic Economic Animal Breeding and Healthy Farming

edited by Yude Wang and Shengwei Luo

submission deadline 31 Jul 2025 | 5 articles | Viewed by 6115 | Submission Open

Keywords: aquaculture economic animal; breeding; genetics; culture; nutrition

(This special issue belongs to the Section Zoology)

Biology and Function of Inflammasomes

edited by

Seung-Yong Seong

submission deadline 31 Jul 2025 | 3 articles | Viewed by 5844 | Submission Open

Keywords: damage-associated molecular patterns; DAMPs; pattern recognition receptor; immune inflammatory response; inflammasome

(This special issue belongs to the Section Immunology)

Milk Oligosaccharides: Biological Functions and Application Prospects

edited by

Chunsheng Jin

submission deadline 31 Jul 2025 | 3 articles | Viewed by 5302 | Submission Open

Keywords: milk oligosaccharides; colostrum; HMO; gut microbiota; immune modulator; prebiotics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Reproductive Physiology and Pathology in Livestock

edited by Claudio Gustavo Ustavo Barbeito and

Fabiano José Ferreira De Sant’Ana

submission deadline 31 Jul 2025 | 3 articles | Viewed by 5057 | Submission Open

Keywords: livestock; animal reproduction; reproductive biology; physiology and pathology of reproduction; experimental models; non-conventional species; biotechnology; immunology

(This special issue belongs to the Section Developmental and Reproductive Biology)

Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

edited by

Apostolos P. Georgopoulos

submission deadline 31 Jul 2025 | 2 articles | Viewed by 4692 | Submission Open

Keywords: HLA; vaccine; antigen; antibody; cancer; binding affinity; biophysical modeling; lymphocytes

Unraveling the Molecular Mechanisms of Development and Stress Tolerance in Vegetables

edited by

Zhansheng Li

Jin Xu

and

Ying Li

submission deadline 31 Jul 2025 | 2 articles | Viewed by 4482 | Submission Open

Keywords: vegetable development; molecular mechanisms; stress tolerance; genetic regulation; epigenetic regulation; biochemical regulation; sustainable agriculture; environmental stress; growth adaptation; crop yield; gene editing; cellular engineering

(This special issue belongs to the Section Plant Science)

Phytoplasmas: Molecular Characterization and Host–Pathogen Interactions (2nd Edition)

edited by

Wei Wei

submission deadline 31 Jul 2025 | 3 articles | Viewed by 4282 | Submission Open

Keywords: molecular diagnosis and epidemiology; host-phytoplasma interactions; genetic diversity; taxonomy and classification; ecology and evolution; insect vectors; disease management; phytoplasma genomics and other omics studies

(This special issue belongs to the Section Microbiology)

The Relationship Between Water Quality and Aquatic Organisms (2nd Edition)

edited by Dong Zhang,

Ming Duan

Miao Wang

Xiangsheng Hong

and Mengmeng Yi

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2873 | Submission Open

Keywords: aquatic animals; water quality; phytoplankton; zooplankton; microorganisms; physiology

The Biodiversity and Ecosystem Dynamics of Deep-Sea Hydrothermal Vents

edited by

Xiang Zeng

and Yadong Zhou

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2768 | Submission Open

Keywords: deep-sea hydrothermal vents; biodiversity; microbiome; biological resources; marine biology

(This special issue belongs to the Section Marine Biology)

Molecular Mechanisms of Sexual and Reproductive Development in Aquatic Animals

edited by

Zhenkui Qin

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2165 | Submission Open

Keywords: aquatic animals; sex; germline; reproduction; regulatory mechanism

(This special issue belongs to the Section Marine Biology)

Cellular and Molecular Mechanisms in Sensory–Metabolic Integration: From Signaling Pathways to Systemic Regulation

edited by

Antonino Maniaci

, Giovanni Giurdanella, Mohamed Amin Zaoual and

Caterina Gagliano

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1828 | Submission Open

Keywords: multisensory disorders; metabolic dysfunction; systemic health; sensory impairments; metabolic syndrome; neurometabolic pathways; vision impairment; hearing loss; vestibular disorders; olfactory dysfunction; gustatory dysfunction; somatosensory impairment; energy homeostasis; integrative medicine

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Advances in Evolutionary Ecology of Host–Parasite Interactions

edited by Xi Huang

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1601 | Submission Open

Keywords: evolutionary ecology; infectious disease; host– parasite interactions; host switching; host specificity; immune response; phylogeography

(This special issue belongs to the Section Infection Biology)

Osteoblast Differentiation in Health and Disease

edited by

Nadia Calabriso

and Maria Annunziata Carluccio

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1477 | Submission Open

Keywords: osteogenesis; mesenchymal stem cells; osteoblast; osteoblast differentiation; bone diseases; transcription factors; epigenetics; extracellular vesicles; inflammatory mediators; bioactive natural compounds

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Tickborne Diseases and Their Vectors

edited by Moses Sibusiso Mtshali

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1407 | Submission Open

Keywords: ticks; tickborne pathogens; epidemiology of tickborne diseases; zoonotic diseases; molecular diagnosis; genetic diversity; immunology; vector control and mapping

(This special issue belongs to the Section Infection Biology)

Advances in Foodborne Pathogens

edited by Qiming Chen

submission deadline 31 Jul 2025 | 1 articles | Viewed by 697 | Submission Open

Keywords: foodborne pathogens; contamination mechanisms; infection mechanisms; detection assays; risk assessment; antibacterial agents or materials

(This special issue belongs to the Section Microbiology)

Advances in Thrombosis and Vascular Biology

edited by Lu Wang

submission deadline 31 Jul 2025 | 1 articles | Viewed by 587 | Submission Open

Keywords: blood and vascular biology; thrombosis; hemostasis; vascular injury

(This special issue belongs to the Section Physiology)

Inflammatory Cells and Repair

edited by

Nanako Kawaguchi

and

Toshio Nakanishi

submission deadline 31 Jul 2025 | Viewed by 365 | Submission Open

Keywords: inflammation; repair; damage

(This special issue belongs to the Section Immunology)

The Role of Non-Coding RNA in Tumorigenesis and Development

edited by Haili Wu

submission deadline 31 Jul 2025 | Viewed by 258 | Submission Open

Keywords: microRNA; lncRNA; circRNA; tumorigenesis; tumor energy metabolism; innate immunity; acquired immunity; tumor immune checkpoint; small-molecule drugs; novel drug targets

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Current Advances in Plants Genome Editing

edited by Xuean Cui

submission deadline 31 Jul 2025 | Viewed by 258 | Submission Open

Keywords: plant genome engineering; CRISPR/Cas; gene knock-out; gene knock-in; base editor; prime editor; genome editing tools; multiplex genome editing; gene expression regulation; plant trait improvement

(This special issue belongs to the Section Genetics and Genomics)

Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control

edited by

Fernando Almeida-Souza

Flávia de Oliveira Cardoso

and

Kátia Da Silva Calabrese

submission deadline 15 Aug 2025 | 7 articles | Viewed by 15247 | Submission Open

Keywords: Leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; clinical studies; treatment; vaccine

(This special issue belongs to the Section Microbiology)

Ferroptosis: Mechanisms and Human Disease

edited by Chan-Yen Kuo

submission deadline 15 Aug 2025 | 2 articles | Viewed by 5490 | Submission Open

Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment

(This special issue belongs to the Section Cell Biology)

Animal Models of Arthritis

edited by Nevena Arsenović-Ranin and Biljana Bufan

submission deadline 30 Aug 2025 | 4 articles | Viewed by 7585 | Submission Open

Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine

(This special issue belongs to the Section Medical Biology)

Metabolic and Stress Responses in Aquatic Animals

edited by

Marcelino Herrera

, Laura Fernández-Alacid and

Ignacio Ruiz-Jarabo

submission deadline 31 Aug 2025 | 13 articles | Viewed by 21098 | Submission Open

Keywords: stress; metabolism; animal welfare; aquaculture; cephalopods; fish; molluscs; crustaceans; aquatic animals; animal physiology

(This special issue belongs to the Section Zoology)

The Replication Licensing System

edited by

Peter J. Gillespie

submission deadline 31 Aug 2025 | 6 articles | Viewed by 20343 | Submission Open

Keywords: cell cycle; DNA replication; genome stability; replication licensing; MCM2-7; ORC; Cdc6; CDT1; cancer; Meier-Gorlin syndrome

(This special issue belongs to the Section Cell Biology)

Infectious Diseases: Emerging Diagnostic Methods, Updated Treatment Protocols and New Antimicrobial Agents

edited by

Andreas G. Tsantes

Dimitrios V. Papadopoulos

Rozeta Sokou

and

Vanesa Bellou

submission deadline 31 Aug 2025 | 6 articles | Viewed by 19504 | Submission Open

Keywords: infectious diseases; pathophysiology; risk factors; prognosis; diagnostic methods; biomarkers; molecular techniques; treatment protocols; novel antibiotic

(This special issue belongs to the Section Infection Biology)

Editorial Board Members' Collection Series: “Biodiversity and Ecosystem Function under Global Change”

edited by

Shucun Sun

and

Panayiotis G. Dimitrakopoulos

submission deadline 31 Aug 2025 | 9 articles | Viewed by 18517 | Submission Open

Keywords: climate change; global warming; precipitation; N deposition; biological invasion; species interaction; microbial process; ecosystem function; ecosystem service

2nd Edition: Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services

edited by

Paraskevi K. Karachle

Elena Tricarico

Giorgio Mancinelli

and

Baran Yoğurtçuoğlu

submission deadline 31 Aug 2025 | 8 articles | Viewed by 14792 | Submission Open

Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation

(This special issue belongs to the Section Marine Biology)

The Effect of Food- and Nutrient-Derived Molecules on Cells and Tissue

edited by

Roberta Moschini

and

Francesca Felice

submission deadline 31 Aug 2025 | 4 articles | Viewed by 12532 | Submission Open

Keywords: natural products; molecules; nutrition; antioxidants; cell biology; metabolism

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Bone Cell Biology

edited by Yohei Abe and

Giulia Lanzolla

submission deadline 31 Aug 2025 | 6 articles | Viewed by 9968 | Submission Open

Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling

(This special issue belongs to the Section Cell Biology)

Pollination Biology

edited by

Yu Gao

submission deadline 31 Aug 2025 | 7 articles | Viewed by 9954 | Submission Open

Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinator insect

(This special issue belongs to the Section Ecology)

Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease

edited by

Mridula Chopra

Helen L. Fillmore

and

Maurizio Forte

submission deadline 31 Aug 2025 | 2 articles | Viewed by 6299 | Submission Open

Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle

Biology, Ecology and Management of Harmful Algae

edited by Paul V. Zimba and

Jabulani R. Gumbo

submission deadline 31 Aug 2025 | 4 articles | Viewed by 5867 | Submission Open

Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources

Lipid Metabolism in Plant Growth and Development

edited by Xiaohong Yu and Yingqi Cai

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2956 | Submission Open

Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process

(This special issue belongs to the Section Plant Science)

Molecular Basis of Seed Germination and Dormancy

edited by

Yifeng Wang

Jiezheng Ying

Xiaohong Tong

and Yu Cheng

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1535 | Submission Open

Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement

(This special issue belongs to the Section Plant Science)

Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control

edited by Honglun Bi

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1211 | Submission Open

Keywords: insect gene editing; genetic regulation ; CRISPR/Cas ; gene drive ; pest control; sex determination ; reproductive development; insect sterile technique

(This special issue belongs to the Section Zoology)

Airway Smooth Muscle and Respiratory Diseases

edited by

Joseph Jude

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1067 | Submission Open

Keywords: airway; airway smooth muscle; asthma; COPD; airway hyperresponsiveness; airway inflammation; airway remodeling; bronchospasm; bronchodilators

(This special issue belongs to the Section Cell Biology)

Adaptation Mechanisms of Forest Trees to Abiotic Stress

edited by

Ling Yang

submission deadline 31 Aug 2025 | 1 articles | Viewed by 956 | Submission Open

Keywords: genetic variation; epigenetic control; plant hormone; nitric oxide; reactive oxygen species; phenomic; metabolomic; genomic; signal transduction; gene function

(This special issue belongs to the Section Plant Science)

Recent Advances in Metabolic Disorders

edited by

Vinood B. Patel

submission deadline 31 Aug 2025 | 1 articles | Viewed by 926 | Submission Open

Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals; alcohol; treatment TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Physiology)

Disease Biomarker Discovery and Validation

edited by Matthew James Jennings

submission deadline 31 Aug 2025 | 1 articles | Viewed by 926 | Submission Open

Keywords: biomarkers; prognostic validation; predictive validation; analytical validation

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Redox Signaling and Oxidative Stress in Health and Disease

edited by

Taeho Kwon

and

Hu-Nan Sun

submission deadline 31 Aug 2025 | 1 articles | Viewed by 902 | Submission Open

Keywords: redox signaling; oxidative stress; antioxidant defense; cellular regulation; aging; cancer; cardiovascular diseases; neurodegenerative diseases; therapeutic approaches; digital biotechnology

(This special issue belongs to the Section Cell Biology)

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