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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Wetland Ecosystems (2nd Edition)

edited by

Jian Li

, Chenglang Pan and Qiang Wang

submission deadline 1 Jun 2026 | 20 articles | Viewed by 48295 | Submission Open

Keywords: biological invasion; pollution; carbon sink function; the biogeochemical cycle of biogenic elements; population and community ecology; global climate change; coastal zone management; the structure and function of the microbiome; environmental adaptation mechanisms of wetland organisms; wetland landscape; wetland degradation

(This special issue belongs to the Section Ecology)

Animal Models of Neurodegenerative Diseases

edited by Xiangyu Guo

submission deadline 1 Jun 2026 | 6 articles | Viewed by 21660 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; Parkinson's disease; Huntington's disease; neuroscience; animal models; pathogenesis

(This special issue belongs to the Section Neuroscience)

Biomarkers in Stress Biology and Ecology

edited by

and

submission deadline 1 Jun 2026 | 4 articles | Viewed by 10587 | Submission Open

Keywords: biomarkers; ecotoxicology; environmental contamination; stress ecology; neurotoxicity; oxidative stress; pollution

Interactions and Cross-Kingdom Regulation of Hosts and Pathogens/Parasites

edited by

Rui Guo

and Jianfeng Qiu

submission deadline 1 Jun 2026 | Viewed by 209 | Submission Open

Keywords: host; pathogen; parasite; interaction; cross-kingdom regulation; immune response; infection

(This special issue belongs to the Section Microbiology)

Sustainable Waste Management: Application of Biotechnology to Reduce Waste

edited by

Sushanta Kumar Saha

and Hande Ermis

submission deadline 1 Jun 2026 | Viewed by 147 | Submission Open

Keywords: sustainable waste management; environmental biotechnology; microbial waste treatment; bioresource valorization; circular economy; waste-to-energy; bioreactors and bioprocesses; enzymatic degradation; industrial and municipal waste treatment

(This special issue belongs to the Section Biotechnology)

Recent Advances in Biosynthesis and Degradation of Plant Anthocyanin

edited by

Qinsong Yang

and

Minjie Qian

submission deadline 15 Jun 2026 | 9 articles | Viewed by 20262 | Submission Open

Keywords: anthocyanin; fruit ripening; flowering coloration; leaf coloration; secondary metabolite; molecular mechanism

(This special issue belongs to the Section Plant Science)

From Basics to Applications of Gene Regulatory Networks

edited by

Thomas Ulas

submission deadline 15 Jun 2026 | 4 articles | Viewed by 8151 | Submission Open

Keywords: gene regulatory networks; computational methods; modeling and simulation; disease mechanisms; therapeutic targeting; transcriptomics

(This special issue belongs to the Section Genetics and Genomics)

Targeting Neuromuscular Plasticity in Injury and Motoneuron Disease

edited by

Rosario Gulino

submission deadline 15 Jun 2026 | 1 articles | Viewed by 476 | Submission Open

Keywords: neural plasticity; dendritic remodelling; axonal sprouting; metabolic changes; mitochondrial dysfunction; amyotrophic lateral sclerosis; motoneuron; spinal cord injury; regenerative medicine

(This special issue belongs to the Section Neuroscience)

Pregnancy Health and Complications: Molecular Processes and Mechanisms

edited by

Shibin Cheng

submission deadline 30 Jun 2026 | 7 articles | Viewed by 44334 | Submission Open

Keywords: placenta; uterine; fetus; adverse pregnancy outcome; preterm birth; preeclampsia; gestational diabetes; maternal– fetal interface; immune tolerance; inflammation

(This special issue belongs to the Section Developmental and Reproductive Biology)

New Insights into Skeletal Muscle Metabolism in Pathological and Physiological Conditions

edited by

Cristina Antinozzi

submission deadline 30 Jun 2026 | 11 articles | Viewed by 17477 | Submission Open

Keywords: skeletal muscle; muscle diseases; hormones; physical exercise; muscle physiology; biomarkers; disease prevention; antibodies; pharmacological approaches; cell metabolism

(This special issue belongs to the Section Cell Biology)

State of the Art in Fish Nutrition: Antimicrobials, Immunostimulants, Synbiotics and Alternative Protein Sources

edited by Jiun-Yan Loh

submission deadline 30 Jun 2026 | 3 articles | Viewed by 8635 | Submission Open

Keywords: probiotics; prebiotics; synbiotics; immunostimulants; antimicrobial peptides; alternative protein/single-cell protein sources; insect meals; aquatic species; metabolisms; disease resistances

(This special issue belongs to the Section Zoology)

Evolution, Genetics, and Conservation of Wildlife Respond to Environmental Changes

edited by Jiang Chang and

Shuping Wang

submission deadline 30 Jun 2026 | 9 articles | Viewed by 6553 | Submission Open

Keywords: environmental change; wildlife; rapid evolution; genetic diversity; conservation genomics; environmental DNA; species distribution models; adaptive evolution; eco-evolutionary dynamics

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Advances in Research on Diseases of Plants (2nd Edition)

edited by

Wei Cheng

submission deadline 30 Jun 2026 | 4 articles | Viewed by 4310 | Submission Open

Keywords: phytopathogen; plant immunity; plant disease resistance; gene expression/regulation; signal regulation; pathogenesis; virulence; genetic engineering; disease control

(This special issue belongs to the Section Plant Science)

Advances in Infection and Genetic Diversity of Zoonotic Parasites, Hosts and Vectors

edited by

Weerachai Saijuntha

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3705 | Submission Open

Keywords: zoonotic parasites; prevalence of infection; helminths; protozoa; vectors; genetic diversity; zoonoses; hosts

(This special issue belongs to the Section Infection Biology)

Current Advances in Echinoderm Research (2nd Edition)

edited by

Muyan Chen

and

Xiutang Yuan

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3553 | Submission Open

Keywords: echinoderms; sea cucumbers; starfish; brittle stars; sea urchins

Plant Stress Physiology: A Trait Perspective

edited by Shuang-Xi Zhou,

Aoxue Wang

and Yanchang Wang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2983 | Submission Open

Keywords: photosynthetic traits; hydraulic traits; metabolic traits; stoichiometric traits; molecular traits; trait plasticity; trait adjustment; stress adaptation; climate resilience

(This special issue belongs to the Section Plant Science)

Research Advances in Aquatic Omics

edited by

Zhengyong Wen

Qiong Shi

and Haiping Liu

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2589 | Submission Open

Keywords: aquatic animals; genomics; transcriptomics; proteomics; metabolomics; genetics; evolutionary biology

(This special issue belongs to the Section Evolutionary Biology)

Metals in Biology (2nd Edition)

edited by

Muhamed Amin

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2375 | Submission Open

Keywords: metalloenzymes; iron sulfur cluster; mn cluster; photosystem I; photosystem II

Advances in Biological Breast Cancer Research (2nd Edition)

edited by Anna-Mart Engelbrecht,

Joji Mercier

and

Iman Van Den Bout

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2115 | Submission Open

Keywords: breast cancer; breast tumor; breast cancer cells; animal models; cell death; cancer diagnosis; cancer treatment; biomarkers; cancer microenvironment; carcinogens; estrogen receptor; molecular biology; cell biology

(This special issue belongs to the Section Cancer Biology)

Latest Research in Cancer Multi-Omics

edited by Philip Anthony Sutera

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1730 | Submission Open

Keywords: cancer; multi-omics; genomics; transcriptomics; proteomics; metabolomics; radiomics; pathomics; precision medicine; artificial intelligence

(This special issue belongs to the Section Bioinformatics)

Precision Nutrition: Unraveling the Molecular Physiology of Nutrient–Gut–Health Axis in Livestock and Poultry

edited by Shengchen Wang, Tingting Li and Xiaoyan Cui

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1504 | Submission Open

Keywords: livestock; poultry; animal production; essential nutrients; bioactive compounds; metabolism; animal health; gut physiology; microbiota; molecular

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Protein Kinases: Key Players in Carcinogenesis

edited by

Yingyu Cui

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1480 | Submission Open

Keywords: protein kinases; carcinogenesis; molecular mechanisms; kinase inhibitors; cancer stem cells

(This special issue belongs to the Section Cancer Biology)

Genomics and Bioinformatics in Microorganism from the Class Insecta

edited by Irám Pablo Rodríguez-Sánchez

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1402 | Submission Open

Keywords: genomics; bioinformatics; microbial communities; insect microbiomes; multi-omics; metagenomics; transcriptomics; host-microbe interactions; evolutionary dynamics; biotechnological applications

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Vector-Borne Diseases: Host Infection Mechanisms, Immune Response and Epidemiology

edited by

Sahatchai Tangtrongsup

and

Nattawooti Sthitmatee

submission deadline 30 Jun 2026 | Viewed by 1319 | Submission Open

Keywords: vector-borne pathogens; host– vector– pathogen interactions; immune response to arthropod-borne infections; vector competence and ecology; one health surveillance; emerging zoonoses; tick-borne diseases; animal vector-borne diseases; veterinary public health

(This special issue belongs to the Section Immunology)

The Plasticity of Autonomic Ganglia

edited by

Miguel Angel Morales

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1132 | Submission Open

Keywords: acetylcholine; GABA; co-transmission; neuroplasticity; transmitter segregation; synapse; gLTP; binge-eating disorders; dysautonomia; heart disease

(This special issue belongs to the Section Neuroscience)

Paper Collection: Understanding Immune Systems

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1100 | Submission Open

Keywords: immune mechanisms; evolutionary immunology; comparative immunology; innate immunity; adaptive immunity; autoimmunity; chronic inflammation; immune ageing; host– pathogen interactions; vaccinology; regenerative medicine

(This special issue belongs to the Section Immunology)

Biology, Ecology and Management of Invasive Alien Plants (2nd Edition)

edited by

Guoqi Chen

and

Jiang Wang

submission deadline 30 Jun 2026 | 1 articles | Viewed by 922 | Submission Open

Keywords: changes in the composition and distribution of alien plants; invasive mechanisms; invasiveness; invasibility; invasive population; invasive plant interactions with other organisms; impacts on environment; ecosystem services and human health; chemical control; management of invasive plants; utilization of invasive plants

(This special issue belongs to the Section Plant Science)

Advancing Crop Nutritional Quality Through Genomic Approaches

edited by Gen Xu

submission deadline 30 Jun 2026 | 1 articles | Viewed by 889 | Submission Open

Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding

(This special issue belongs to the Section Plant Science)

Nutritional Physiology of Animals

edited by

Bai Xue

Yuhong Gao

and Jia Zhou

submission deadline 30 Jun 2026 | 1 articles | Viewed by 652 | Submission Open

Keywords: animals; nutrition; feed additives; novel feed resources; physiology; digestibility; metabolism; stress; reproduction; multi-omics

(This special issue belongs to the Section Physiology)

Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease

edited by

Sorina Dinescu

submission deadline 30 Jun 2026 | Viewed by 555 | Submission Open

Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication

(This special issue belongs to the Section Cell Biology)

Interactions Between Membrane Proteins and Membrane Lipids

edited by

Youzhong Guo

submission deadline 30 Jun 2026 | Viewed by 496 | Submission Open

Keywords: membrane protein; lipid bilayer; enzyme; channel; receptor; transporter; cryo-EM; X-ray crystallography; structural biology; drug target

(This special issue belongs to the Section Biophysics)

Mechanisms of Drug Resistance in Cancer Cells

edited by

Xin Chen

Tuoen Liu

and

Wei Lei

submission deadline 30 Jun 2026 | Viewed by 399 | Submission Open

Keywords: drug resistance; mechanisms; cell growth; cell proliferation; efficacy

(This special issue belongs to the Section Medical Biology)

Applications of Yeast Biotechnology

edited by

Pornthap Thanonkeo

submission deadline 30 Jun 2026 | Viewed by 211 | Submission Open

Keywords: biofuel and feed production; biological control; waste treatment and utilization; yeast metabolites; enzyme technology; yeast strain development; process development

(This special issue belongs to the Section Biotechnology)

Genetic Breeding and Reproduction of Aquatic Animals—2nd Edition

edited by

Huaping Zhu

, Dongmei Ma and

Zaixuan Zhong

submission deadline 30 Jun 2026 | Viewed by 159 | Submission Open

Keywords: genetic breeding; reproduction technology; gene; protein; molecular marker; trait; QTLs; molecular marker; fish; shrimp; crab; shellfish; aquatic animals; transcriptomics; proteomics; metabonomics

(This special issue belongs to the Section Zoology)

Breaking Barriers in Metabolic Health: Novel Insights into Obesity and Metabolic Disorders

edited by Aijun Qiao

submission deadline 30 Jun 2026 | Viewed by 139 | Submission Open

Keywords: metabolic disorders; pathogenesis and mechanisms; biomarkers

(This special issue belongs to the Section Medical Biology)

Environmental and Disease-Driven Biomechanical Stress in Red Blood Cell Biology

edited by

Marijke Grau

submission deadline 30 Jun 2026 | Viewed by 123 | Submission Open

Keywords: RBCs and environmental factors; RBCs and biomechanical stress; RBCs and pathological conditions; RBCs and microcirculation; RBCs and biomarkers for diseases

(This special issue belongs to the Section Biophysics)

Cytochrome P450s Across Biological Systems: From Molecular Mechanisms to Biotechnological and Biomedical Applications

edited by

Pradeepraj Durairaj

submission deadline 30 Jun 2026 | Viewed by 110 | Submission Open

Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; biocatalysis and biotransformation; orphan enzymes; redox biology; structural biology; synthetic biology; enzyme engineering; multi-omics approaches

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Novel Insights of Bone Repair: Strategies for Improvement, Microscopic, Molecular and Ultrastrastructural Aspects—2nd Edition

edited by

Roberta Okamoto

submission deadline 30 Jun 2026 | Viewed by 108 | Submission Open

Keywords: bone repair; aging; bone remodeling; biomaterials; drug delivery; bone regeneration

(This special issue belongs to the Section Medical Biology)

Biosynthesis and Regulation of Plant Tissue-Specific Metabolites

edited by

Xiumin Fu

submission deadline 30 Jun 2026 | Viewed by 94 | Submission Open

Keywords: underground tissue metabolites; root; root exudates; genetic regulation; rhizosphere microbial interaction; environmental response

(This special issue belongs to the Section Plant Science)

Immune Response Regulation in Animals (2nd Edition)

edited by

Rong Gao

and

Hua-Ji Qiu

submission deadline 30 Jun 2026 | Viewed by 91 | Submission Open

Keywords: immunoregulation of animals; vaccination; immunomodulators; immune memory; cytokine; biotechnology; immune response; molecular networks

(This special issue belongs to the Section Immunology)

The Role of Epigenetics in Cell Fate Determination, Cancer Development, and Aging

edited by

Yong Tao

and

Wenbing Xie

submission deadline 30 Jun 2026 | Viewed by 82 | Submission Open

Keywords: epigenetics; cell fate determination; cell fate determination; cancer epigenetics; aging; DNA methylation; histone modification; chromatin remodeling; epigenome editing; epigenetic therapy; stem cells

(This special issue belongs to the Section Cell Biology)

One Health Insights: From Molecules to Ecosystems

edited by Leonardo Oliveira Reis and Lucas Assoni

submission deadline 30 Jun 2026 | Viewed by 72 | Submission Open

Keywords: One Health; environmental health; planetary health; cancer epidemiology; comparative oncology; emerging diseases; immuno-oncology; molecular mechanisms

Neurogenetics of Behaviour—2nd Edition

edited by

Charalambos Kyriacou

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: behaviour; genetics; molecules; species; brain; networks; health; disease

(This special issue belongs to the Section Genetics and Genomics)

Feature Papers in 'Conservation Biology and Biodiversity' (2nd Edition)

edited by

Ettore Randi

submission deadline 1 Jul 2026 | 1 articles | Viewed by 413 | Submission Open

Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Research on the Interaction Mechanism Between Animal Intestine and Its Microbiota

edited by

Zongjie Li

and Xiaomin Guo

submission deadline 1 Jul 2026 | Viewed by 280 | Submission Open

Keywords: animal disease; innate immunity; gut microbiota; gut barrier; immune homeostasis

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Microbial Responses, Pollutant Toxicity Mechanisms, and Human Health Implications

edited by

Chao Song

, Zhongquan Jiang and

Jiale Chen

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1007 | Submission Open

Keywords: heavy metal and emerging pollutants; microbiology and plant physiology; aquatic biology; environmental chemistry; anthropogenic disturbances; machine learning; pangenome analysis; computational toxicology; human health

Ultrastructure and Function in In Vitro Cancer Models: From Morphology to Mechanism

edited by

Michela Relucenti

and

Katia Cortese

submission deadline 15 Jul 2026 | 1 articles | Viewed by 585 | Submission Open

Keywords: cancer; organoids; spheroids; transmission electron microscopy; scanning electron microscopy; focused ion beam (FIB)

(This special issue belongs to the Section Cancer Biology)

Plant Perception, Behavior, and Environmental Response Mechanisms

edited by

Silvia Guerra

and Bianca Bonato

submission deadline 15 Jul 2026 | Viewed by 67 | Submission Open

Keywords: plant perception; plant movement; social cognition; communication; plant behavior; climbing plants; interactions; plant– plant interactions; environment; plant– environment interactions

(This special issue belongs to the Section Plant Science)

Methods in Bioinformatics and Computational Biology

edited by

Xingjian Chen

submission deadline 25 Jul 2026 | 1 articles | Viewed by 790 | Submission Open

Keywords: bioinformatics; computational biology; machine learning in biomedicine; artificial intelligence; single-cell and spatial transcriptomics analysis; biological network analysis; high-throughput data analysis

Tissue and Organ Regeneration in Fish: Evolutionary Mechanisms

edited by Yujun Liang

submission deadline 30 Jul 2026 | 1 articles | Viewed by 5198 | Submission Open

Keywords: organ and tissue regeneration; regeneration mechanisms; progenitor cells; dedifferentiation; fishes; evolutionary adaptation; genetic regulation; signaling pathways; comparative genomics

(This special issue belongs to the Section Evolutionary Biology)

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