Targeting Neuromuscular Plasticity in Injury and Motoneuron Disease
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Neuroscience".
Deadline for manuscript submissions: 15 June 2026 | Viewed by 1085
Special Issue Editor
Interests: neuroscience; neural plasticity; amyotrophic lateral sclerosis; spinal cord injury; motoneuron; regenerative medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Plastic changes, such as synaptic plasticity, synaptogenesis, fiber sprouting, dendritic remodeling and metabolic changes, are typical events associated with activity-dependent modification of neural circuits, including those responsible for compensatory changes occurring after various injury events, including stroke or mechanical damage to the central nervous system. An increasing body of evidence suggests that neuroplasticity could also be responsible for compensatory attempts during the progression of neurodegenerative disorders, including motoneuron diseases. As a result, symptom onset usually occurs long after the initiation of neuronal degeneration.
Although these compensatory plastic changes are unable to halt disease progression or repair damaged tissues, they represent an important mechanism for further study, as well as a promising target of therapy approaches.
Focusing exclusively on basic research, this Special Issue invites contributions that utilise experimental models to explore the role of plasticity in spinal cord injury or motoneuron diseases. We are particularly interested in studies that elucidate the fundamental biological processes of pathogenesis and repair. Research articles and reviews with a strong emphasis on mechanistic discoveries are welcome.
Dr. Rosario Gulino
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neural plasticity
- dendritic remodelling
- axonal sprouting
- metabolic changes
- mitochondrial dysfunction
- amyotrophic lateral sclerosis
- motoneuron
- spinal cord injury
- regenerative medicine
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
