Special Issue "Bioactivity of Medicinal Plants and Extracts"

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Plant Science".

Deadline for manuscript submissions: 31 March 2021.

Special Issue Editors

Dr. Francisco Les
Website
Guest Editor
1. Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, 50830 Villanueva de Gállego (Zaragoza), Spain
2. Instituto Agroalimentario de Aragón-IA2 (CITA-Universidad de Zaragoza), 50059 Zaragoza, Spain
Interests: pharmacology and pharmacy; pharmacognosy; ethnopharmacology; plant science; medicinal plants; food science; natural products; nutrition and dietetics; bioactive foods
Dr. Víctor López
Website
Co-Guest Editor
1. Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge
2. Instituto Agroalimentario de Aragón-IA2 (CITA-Universidad de Zaragoza)
Interests: natural products; functional foods; medicinal plants; bioactive compounds; polyphenols; anthocyanins; antioxidants; enzyme inhibitors
Special Issues and Collections in MDPI journals
Dr. Guillermo Cásedas
Website
Co-Guest Editor
Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge
Interests: natural products; berries; neuroprotection; anthocyanins; antioxidants; cell culture

Special Issue Information

Dear Colleagues,

Medicinal plants and natural products have played a central role in therapeutics, being considered the origin of Pharmacy and Pharmacology. Plants are still a source in nature to obtain and isolate molecules with pharmacological applications (drug discovery) but can also be used as herbal medicinal products in traditional or complementary medicine.

In addition, the WHO has launched a Traditional Medicine Strategy (2014–2023), including herbal medicines as medicinal therapies, with the aim to ensure the quality, safety, proper use, and effectiveness of traditional medicines, among other objectives.

For all these reasons, this Special Issue on “Bioactivity of Medicinal Plants and Extracts” includes a collection of original research and review articles on new advances in the development and application of bioactive compounds and extracts from plant matrices.

Dr. Francisco Les
Dr. Víctor López
Dr. Guillermo Cásedas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Medicinal plants
  • Herbal medicines
  • Bioactive compounds
  • Pharmacognosy
  • Plant extracts
  • Polyphenols
  • Ethopharmacogy
  • Essential oils
  • Aromatic plants
  • Antioxidants
  • Natural products
  • Phytochemicals

Published Papers (2 papers)

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Research

Open AccessArticle
Salvia Spp. Essential Oils against the Arboviruses Vector Aedes albopictus (Diptera: Culicidae): Bioactivity, Composition, and Sensorial Profile—Stage 1
Biology 2020, 9(8), 206; https://doi.org/10.3390/biology9080206 - 04 Aug 2020
Abstract
Mosquito-borne arboviruses diseases cause a substantial public health burden within their expanding range. To date, their control relies on synthetic insecticides and repellents aimed to control the competent mosquito vectors. However, their use is hampered by their high economic, environmental, and human health [...] Read more.
Mosquito-borne arboviruses diseases cause a substantial public health burden within their expanding range. To date, their control relies on synthetic insecticides and repellents aimed to control the competent mosquito vectors. However, their use is hampered by their high economic, environmental, and human health impacts. Natural products may represent a valid eco-friendly alternative to chemical pesticides to control mosquitoes, and mosquito-borne parasitic diseases. The aim of this work was to combine the chemical and sensorial profiles with the bioactivity data of Salvia spp. essential oils (EOs) to select the most suitable EO to be used as a repellent and insecticide against the invasive mosquito Aedes albopictus (Diptera: Culicidae), vector of pathogens and parasites, and to describe the EOs smell profile. To do this, the EOs of four Salvia species, namely S. dolomitica, S. dorisiana, S. sclarea, and S. somalensis were extracted, chemically analyzed and tested for their bioactivity as larvicides and repellents against Ae. albopictus. Then, the smell profiles of the EOs were described by a panel of assessors. The LC50 of the EOs ranged from 71.08 to 559.77 μL L−1 for S. dorisiana and S. sclarea, respectively. S. sclarea EO showed the highest repellence among the tested EOs against Ae. albopictus females (RD95 = 12.65 nL cm−2), while the most long-lasting, at the dose of 20 nL cm−2, was S. dorisiana (Complete Protection Time = 43.28 ± 3.43 min). S. sclarea EO showed the best smell profile, while S. dolomitica EO the worst one with a high number of off-flavors. Overall, all the EOs, with the exception of the S. dolomitica one, were indicated as suitable for “environmental protection”, while S. dorisiana and S. sclarea were indicated as suitable also for “Body care”. Full article
(This article belongs to the Special Issue Bioactivity of Medicinal Plants and Extracts)
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Open AccessArticle
Cytotoxic, Antioxidant, and Enzyme Inhibitory Properties of the Traditional Medicinal Plant Matthiola incana (L.) R. Br.
Biology 2020, 9(7), 163; https://doi.org/10.3390/biology9070163 - 13 Jul 2020
Abstract
Matthiola incana (L.) R. Br. (Brassicaceae) is widely cultivated for ornamental purposes and utilized as a medicinal plant. In the present work, the hydroalcoholic extract from the aerial parts of this species has been evaluated in different bioassays in order to detect potential [...] Read more.
Matthiola incana (L.) R. Br. (Brassicaceae) is widely cultivated for ornamental purposes and utilized as a medicinal plant. In the present work, the hydroalcoholic extract from the aerial parts of this species has been evaluated in different bioassays in order to detect potential pharmacological applications. The cytotoxic capacity against the human colorectal adenocarcinoma (CaCo-2) and breast cancer (MCF-7) cell lines was tested using the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. The extract was investigated as a neuroprotective inhibitor of central nervous system (CNS) enzymes such as monoamine oxidase A, tyrosinase, acetylcholinesterase, and as a natural enzyme inhibitor of α-glucosidase and lipase involved in some metabolic disorders such as obesity or type 2 diabetes. The antioxidant ability was also evaluated in an enzymatic system (xanthine/xanthine oxidase assay). Results showed that the M. incana extract displayed moderate to low cytotoxicity vs. CaCo-2 cells. The extract acted as a superoxide radical scavenger and enzymatic inhibitor of monoamine oxidase A, tyrosinase, α-glucosidase, and lipase. The best results were found in the α-glucosidase assay, as M. incana hydroalcoholic extract was able to inhibit the enzyme α-glucosidase up to 100% without significant differences, compared to the antidiabetic drug acarbose. Matthiola incana has been demonstrated to exert different biological properties. These are important in order to consider this species as a source of bioactive compounds. Full article
(This article belongs to the Special Issue Bioactivity of Medicinal Plants and Extracts)
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