Implications of Bioactive Compounds in Lifelong Disorders: 2nd Edition
A special issue of Life (ISSN 2075-1729).
Deadline for manuscript submissions: 30 April 2026 | Viewed by 305
Special Issue Editors
2. Instituto Agroalimentario de Aragón-IA2, CITA-Universidad de Zaragoza, 50059 Zaragoza, Spain
Interests: natural products; western blot; neuroprotection; polyphenols; antioxidants; cell culture; oxidative stress; phytochemicals
Special Issues, Collections and Topics in MDPI journals
2. Instituto Agroalimentario de Aragón-IA2, CITA-Universidad de Zaragoza, 50059 Zaragoza, Spain
Interests: pharmacology and pharmacy; pharmacognosy; ethnopharmacology; plant science; medicinal plants; food science; natural products; nutrition and dietetics; bioactive foods
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The regulation of oxidative stress plays a fundamental role in several physiological and pathological processes, encompassing the modulation of the inflammatory response, cellular proliferation, apoptotic activity, and immune responses. In addition, its relationship with various diseases has been studied, such as inflammatory bowel diseases (IBDs), cardiovascular and neurodegenerative disorders, cancer, and metabolic syndromes.
Over the past few decades, coordinated solutions have been proposed to remedy these intracellular imbalances. Within this context, bioactive compounds have emerged as pivotal candidates due to changes in scientific perspectives and growing concern within society about understanding the food ecosystem.
The benefits that these bioactive compounds can provide will depend on their redox signalling mechanisms. Many of them possess antioxidant properties and can act as electron donors, neutralizing free radicals and reducing oxidative stress. This helps to ensure the maintenance of a proper redox balance in cells and prevents oxidative damage to biomolecules such as lipids, proteins, and DNA.
These compounds can act as key modulators in regulating cellular processes, which could have a significant impact on health and well-being.
This Special Issue revolves around the search for bioactive compounds and their impact on cellular signalling, unveiling new avenues of action within known signalling pathways. These compounds offer a promising opportunity to prevent the development of neurodegenerative and cardiovascular diseases.
Studying their effect on lifelong disorders provides a deeper understanding of these underlying mechanisms and may lead to the development of innovative therapeutic interventions in the future.
In this sense, several studies are relevant to this Special Issue, including systematic reviews and metanalyses, clinical trials, and preclinical studies. Submitted manuscripts must include sufficiently detailed descriptions of the composition and stability of the study material when addressing plant extracts or other natural compounds.
Dr. Guillermo Cásedas
Dr. Francisco Les
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- phytochemicals
- functional food
- oxidative stress
- metabolic syndrome
- neuroinflammation
- antioxidant
- polyphenols
- diabetes
- inflammatory bowel disease
- natural products
- neurodegenerative disease
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
