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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Healthcare: Harnessing AI for Diagnostic and Therapeutic Innovations

edited by Wei-Chang Yeh

submission deadline 30 Sep 2025 | 2 articles | Viewed by 5063 | Submission Open

Keywords: artificial intelligence; personalized healthcare; medicine; bioengineering; machine learning

(This special issue belongs to the Section Biosignal Processing)

Biomaterials and Technology for Tumor Engineering

edited by

Girdhari Rijal

and

Narayan Bhattarai

submission deadline 30 Sep 2025 | 1 articles | Viewed by 4512 | Submission Open

Keywords: three-dimensional tumor models; xenograft tumors; cancer cell signatures; H-scan ultrasound; in vivo imaging systems; dye-tagged cell technologies; scaffolds; tumoroids; spheroids; anticancer drugs

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Cartilage and Bone Tissue Engineering: Second Edition

edited by

Francesca Scalera

submission deadline 30 Sep 2025 | 4 articles | Viewed by 4166 | Submission Open

Keywords: cartilage; bone; scaffolds; stem cells; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Dental Implant Reconstruction and Biomechanical Evaluation, 2nd Edition

edited by

Bongju Kim

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3320 | Submission Open

Keywords: dental materials; dental implants; dental prosthesis; implant-supported prosthesis; FEA; FEM; computational modelling; biomechanical characterization

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Periodontics and Implant Dentistry

edited by

Sergio Alexandre Gehrke

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2261 | Submission Open

Keywords: periodontics; implantology; technological advances; periodontal health; dental implants; digital planning; guided tissue regeneration; laser therapy; biomaterials; minimally invasive therapies; 3D printing; artificial intelligence; cone beam computed tomography (CBCT); biomodulation; peri-implantitis; tissue engineering; sustainability in dentistry; stem cells; bioprinting; oral rehabilitation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for the Repair and Regeneration of Musculoskeletal Tissue

edited by Christopher Bibbo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2037 | Submission Open

Keywords: musculoskeletal; soft tissue; bone; cartilage; nerve; regenerative medicine; reconstructive surgery

(This special issue belongs to the Section Regenerative Engineering)

Applications of Computational Modeling in Biomedical Image and Signal Processing—2nd Edition

edited by Xuxin Chen and

Bin Zheng

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1910 | Submission Open

Keywords: computational modeling; quantitative disease markers; medical image processing; image segmentation; biosignal testing; biosignal processes; feature selection; deep learning; computer-aided diagnosis; data standardization; synthetic data generation

(This special issue belongs to the Section Biosignal Processing)

Wearable, Flexible, and Integrated Microfluidic-Based Biosensors for Point-of-Care Testing Applications

edited by Madhusudan B. Kulkarni

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1785 | Submission Open

Keywords: biomedical electronic devices; health-monitoring wearables; implantable sensors; bioelectronic medicine; personalized healthcare

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Development of Bioelectrochemical Systems for Environmental Engineering

edited by

Shiue-Lin Li

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1672 | Submission Open

Keywords: bioelectrochemical systems; microbial fuel cells; bioelectrosynthesis; high-added value chemicals; environmental engineering

(This special issue belongs to the Section Biochemical Engineering)

Artificial Intelligence for Biomedical Signal Processing, 2nd Edition

edited by

Verónica Barroso-García

and

Fernando Vaquerizo-Villar

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1607 | Submission Open

Keywords: aid diagnosis; automatic diagnosis; biomedical signals; biomedical signal processing; deep learning; diseases; explainable artificial intelligence; machine learning; physiological time series; predictive models

(This special issue belongs to the Section Biosignal Processing)

Hydrogels for Biomedical Applications, 2nd Edition

edited by

Pallabi Pal

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1199 | Submission Open

Keywords: drug delivery systems; surface modified biomaterials; self-healing hydrogels; thermoresponsive hydrogels; injectable hydrogels; tissue regeneration; 3D printing; bioactive hydrogels

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of AI in Biomedical Engineering for Healthy Ageing

edited by

Sai Kit Lam

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1184 | Submission Open

Keywords: artificial intelligence in healthy aging; aging-associated diseases; cancer; deep learning; image segmentation and classification; machine learning; medical image analysis; personalized medicine; prognostication; risk stratification

(This special issue belongs to the Section Biosignal Processing)

Breast Cancer: From Precision Medicine to Diagnostics

edited by Kosuke Kawaguchi

submission deadline 30 Sep 2025 | 2 articles | Viewed by 950 | Submission Open

Keywords: breast cancer; precision medicine; diagnostics; novel treatment options; personalized treatment; tumor microenvironment; breast imaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Partial Differential Equations in Bioengineering

edited by

José Alberto Rodrigues

and

Jacinta Serpa

submission deadline 30 Sep 2025 | Viewed by 477 | Submission Open

Keywords: Partial Differential Equations; bioengineering modeling; mathematical biology; tissue engineering; biomechanics; biomedical imaging; fluid dynamics in biology; heat transfer in tissues; drug diffusion modeling; systems biology; epidemic modeling; mathematical models of physiological processes; numerical methods in bioengineering; biological signal processing; computational biology; multiscale modeling; mathematical modeling in regenerative medicine; multi-OMICs in health and disease

Microalgae Biotechnology and Microbiology: Prospects and Applications

edited by Dora Allegra Carbone and Michael Melkonian

submission deadline 30 Sep 2025 | 1 articles | Viewed by 461 | Submission Open

Keywords: microalgae; bacteria; photobioreactor; bioengineering; biomass; wastewater; compounds

(This special issue belongs to the Section Biochemical Engineering)

Machine Learning and Artificial Intelligence for Biomedical Applications, 3rd Edition

edited by

Crescenzio Gallo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 452 | Submission Open

Keywords: artificial intelligence models; biomedicine; machine learning methods; artificial neural networks; precision medicine; personalized health care

(This special issue belongs to the Section Biosignal Processing)

Challenges for Managing Glaucoma in the 21st Century

edited by

Karanjit S. Kooner

submission deadline 30 Sep 2025 | Viewed by 390 | Submission Open

Keywords: retinal imaging; artificial intelligence; minimally invasive glaucoma surgeries (MIGSs); telemedicine; neuroimaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence and Nanotechnology in Cancer Therapy

edited by Wancheng Guo and

Aarti Sharma

submission deadline 30 Sep 2025 | Viewed by 384 | Submission Open

Keywords: AI; nanotechnology; cancer therapy

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Engineering Biomaterials for Regenerative Medicine Applications

edited by

Ramar Thangam

Heemin Kang

and Venugopal Krishnan

submission deadline 30 Sep 2025 | Viewed by 359 | Submission Open

Keywords: biomaterials; tissue repair; regenerative medicine; stem cells; immune cells; cancer therapy; biomedical devices and implants; tissue regeneration

(This special issue belongs to the Section Regenerative Engineering)

Musculoskeletal Bioengineering: Imaging and Computational Modeling in Biomechanics

edited by Geoffrey Handsfield

submission deadline 30 Sep 2025 | Viewed by 335 | Submission Open

Keywords: musculoskeletal bioengineering; biomechanics; imaging; computational modeling; musculoskeletal system; biomedical engineering; orthopedics

(This special issue belongs to the Section Biosignal Processing)

Design and Control Innovations in Prosthetic Hands: From Appearance to Advanced Functionality

edited by

Wenjun (Chris) Zhang

submission deadline 30 Sep 2025 | Viewed by 228 | Submission Open

Keywords: prosthetic hands; biomechanics; neural control systems; soft prosthetics; advanced materials; user-centered design; 3D printing in prosthetics; wireless control systems; mind-controlled prosthetics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Flexible Bioelectronics: Pioneering Innovations in Healthcare and Medicine

edited by George Luka and Sujung Kim

submission deadline 30 Sep 2025 | Viewed by 175 | Submission Open

Keywords: flexible bioelectronics; bioelectronics; biosensors; wearable microneedle biosensors; soft electronics; stretchable electronics; smart healthcare technologies

(This special issue belongs to the Section Biosignal Processing)

Advances in Drug Delivery in Cancer Treatment

edited by

Chang Yang

submission deadline 30 Sep 2025 | Viewed by 167 | Submission Open

Keywords: cancer; drug delivery; nanotechnology; targeted therapy; combination therapy; biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Bioengineering and the Eye—3rd Edition

edited by

Dimitrios Karamichos

submission deadline 30 Sep 2025 | Viewed by 143 | Submission Open

Keywords: stem cell therapies; functional ocular tissue equivalents; biomaterials; 3D bioprinting; tissue engineering

(This special issue belongs to the Section Regenerative Engineering)

Bioengineering Cardiovascular Cell and Gene Therapies: Advances and Translational Challenges

edited by

Emre Bektik

and

Kurt Pfannkuche

submission deadline 30 Sep 2025 | Viewed by 140 | Submission Open

Keywords: myocardial infarction; atherosclerosis; peripheral artery disease (PAD); stem cells differentiation; iPSCs disease modeling; biomaterials; gene delivery; tissue engineering approaches; vascular regeneration; cardiac repair; CRISPR gene editing; bio-scaffolds; bioprinting; microfluidics; organ-on-a-chip; immunomodulation; exosomes; drug delivery; clinical translation

(This special issue belongs to the Section Regenerative Engineering)

Multiscale Modeling in Computational Biomechanics: When Contemporary AI Meets Virtual Human Twin

edited by

Tien Tuan Dao

submission deadline 30 Sep 2025 | Viewed by 130 | Submission Open

Keywords: multiscale modeling; computational biomechanics; AI-driven biomechanics; virtual human twin; generative AI in medicine

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Contribution of Bioprocess Engineering to the Achievement of the UN Sustainable Development Goals (SDGs)

edited by

Dirk Holtmann

submission deadline 30 Sep 2025 | Viewed by 108 | Submission Open

Keywords: bioprocess engineering; sustainability; sustainable development goals (SDGs)

(This special issue belongs to the Section Biochemical Engineering)

Cardiovascular Models and Biomechanics

edited by

Hwa Liang Leo

submission deadline 30 Sep 2025 | Viewed by 95 | Submission Open

Keywords: vascular mechanics; patient-specific modeling; cardiovascular devices; mechanobiology; experimental methods; computational modeling; machine learning

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Technological Advances in Neurorehabilitation

edited by

Susan Duff

and Andria J. Farrens

submission deadline 30 Sep 2025 | Viewed by 81 | Submission Open

Keywords: assistive technology; neuroimaging; neurorehabilitation; robotics; wearables

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Reinforcement Learning and Neuromodulators: Bridging Neuroscience and Artificial Intelligence

edited by

Incheol Seo

and

Hyunsu Lee

submission deadline 30 Sep 2025 | Viewed by 78 | Submission Open

Keywords: reinforcement learning; neuromodulators; neuroscience; Artificial Intelligence (AI)

(This special issue belongs to the Section Biosignal Processing)

Bio-Applications of Engineered Escherichia coli—Second Volume

edited by

Joana Rodrigues

and

Debora Ferreira

submission deadline 30 Sep 2025 | Viewed by 62 | Submission Open

Keywords: Escherichia coli; heterologous production; biosynthetic pathways; value-added compounds; microbial chassis; microbial host; biosensors; whole-cell biosensors; diagnosis tools; therapeutic tools

(This special issue belongs to the Section Biochemical Engineering)

Recent Advances in Artificial Intelligence Paradigms for the Detection and Diagnosis of Neurological Diseases

edited by

Yunfeng Wu

submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open

Keywords: biomedical signal processing; artificial intelligence; data mining

(This special issue belongs to the Section Biosignal Processing)

Innovations in Hollow Viscera Imaging: Engineering Breakthroughs and Clinical Translation

edited by

and

submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open

Keywords: hollow viscera imaging; bioengineered diagnostics; AI in endoscopy; minimally invasive devices; functional luminal mapping; smart stents & microsensors; computational biomechanics; clinical translation

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence and Wearable Biosensors for Precision Medicine: Integrating Technology

edited by

Matteo Frigerio

submission deadline 30 Sep 2025 | Viewed by 32 | Submission Open

Keywords: healthcare; gynecology; pelvic floor medicine; pelvic floor rehabilitation; pelvic floor training; laparoscopy; pelvic organ prolapse; urinary incontinence; anal incontinence; overactive bladder; ultrasound; urodynamics; urogynecology; new technologies; pelvic pain; laser; radiofrequency; magnetic stimulation; functional electrical stimulation; biofeedback; vaginal rejuvenation; electronic bladder diaries; sacral neuromodulation; women’ s health

(This special issue belongs to the Section Biosignal Processing)

Biomaterial- and Engineering-Based Approaches for Organoids

edited by Xiuzhi Susan Sun

submission deadline 30 Sep 2025 | Viewed by 24 | Submission Open

Keywords: organoids; biomaterials; tissue engineering; three-dimensional bioprinting; microfluidics; extracellular matrix; disease modeling; regenerative medicine; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Strategies for Ophthalmic Diseases

edited by

Jae Yong Kim

submission deadline 30 Sep 2025 | Viewed by 21 | Submission Open

Keywords: ophthalmic diseases; imaging technology; artificial intelligence; retinal regeneration; corneal implants; drug delivery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Artificial Intelligence for Medical Diagnosis

edited by Alessio Luschi and Pietro Rubegni

submission deadline 30 Sep 2025 | Viewed by 19 | Submission Open

Keywords: healthcare; medicine; artificial intelligence; deep learning; machine learning; generative AI

(This special issue belongs to the Section Biosignal Processing)

Strategies for Microbial Bioprocess Optimization

edited by

Razieh Rafieenia

submission deadline 30 Sep 2025 | Viewed by 15 | Submission Open

Keywords: metabolic engineering; fermentation; synthetic biology; bioreactor design; synthetic microbial communities; machine learning based process design; renewable substrates; life cycle assessment

(This special issue belongs to the Section Biochemical Engineering)

Advanced Bioprocessing Approaches in Energy and Nutrient Recovery from Waste

edited by

Rajinikanth Rajagopal

and

Chunjiang An

submission deadline 30 Sep 2025 | Viewed by 12 | Submission Open

Keywords: anaerobic digestion; biogas production; biogas upgrading; hydrothermal carbonization; thermochemical processes; microbial communities; manure management; wastewater treatment; nutrient recovery; energy recovery; computational modeling; machine learning; circular economy; methane yield; nitrogen recovery; phosphorus recovery

(This special issue belongs to the Section Biochemical Engineering)

Three-Dimensional Printing in Modern Dentistry: State of the Art, Benefits and Future Prospects

edited by

Saverio Capodiferro

Massimo Corsalini

and

Giuseppe D'Albis

submission deadline 30 Sep 2025 | Viewed by 11 | Submission Open

Keywords: additive manufacturing; 3D printing; dentistry; CAD/CAM systems; biocompatible materials; clinical applications; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Dental Materials for Restorative Dentistry

edited by Feng Gao

submission deadline 30 Sep 2025 | Viewed by 11 | Submission Open

Keywords: denal restoration; restorative dentistry; dental biomaterials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Novel Biomaterial Design and Strategies for Musculoskeletal Tissue Engineering

edited by

Jiannan Li

Sien Lin

Ni Su

and Ning Zhang

submission deadline 1 Oct 2025 | 3 articles | Viewed by 6851 | Submission Open

Keywords: biomaterials; bioprinting; tissue engineering; hydrogels; stem cells; orthopaedic surgery; musculoskeletal tissues; bone regeneration

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Orthodontic Biomechanics

edited by Joanna Lis

submission deadline 15 Oct 2025 | 2 articles | Viewed by 1970 | Submission Open

Keywords: orthodontic biomechanics; skeletal anchorage; absolute anchorage

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Orthopedic and Trauma Biomechanics

edited by

Ligia Rusu

Nejc Šarabon

and

Mihnea Ion Marin

submission deadline 16 Oct 2025 | Viewed by 102 | Submission Open

Keywords: biomechanics; gait; trauma and biomechanics; movement; orthopedic assessment

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Recent Progress in Biomedical Image Processing and Analysis

edited by

Dildar Hussain

and Jawad Khan

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4493 | Submission Open

Keywords: biomedical imaging; image processing; image analysis; artificial intelligence; machine learning; medical diagnosis; precision medicine; healthcare technology

(This special issue belongs to the Section Biosignal Processing)

Machine Learning and Eye Movements: Insights into Learning and Autism Spectrum Disorders

edited by

Zoi Kapoula

and Alae Eddine El Hmimdi

submission deadline 20 Oct 2025 | Viewed by 9 | Submission Open

Keywords: eye movements; dyslexia; attention deficit disorders (ADDs); autism spectrum disorders (ASDs); learning disorders; artificial intelligence (AI); eye tracking technology; AI for early screening; explainable AI (XAI); anomaly detection

(This special issue belongs to the Section Biosignal Processing)

Biomechanics and Motion Analysis

edited by

Christina Zong-Hao Ma

and

Hong Fu

submission deadline 31 Oct 2025 | 15 articles | Viewed by 16702 | Submission Open

Keywords: biomechanics; motion capture and analysis; sports and rehabilitation engineering; artificial intelligence; assistive technology

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Medical Devices and Implants, 2nd Edition

edited by Tanvir Faisal, Christine Walck and Donald Sorrells

submission deadline 31 Oct 2025 | 6 articles | Viewed by 11757 | Submission Open

Keywords: implant; medical devices; prototyping; 3D printing; scaffolds; tissue engineering; additive manufacturing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Innovations in Regenerative Therapy: Cell and Cell-Free Approaches

edited by

Prakash Gangadaran

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7577 | Submission Open

Keywords: cell-based therapies; MSCs; exosome; extracellular vesicles; bio nanovesicles; wound; ischemia; hair growth; brain; degenerative diseases

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Application of Bioengineering to Implant Dentistry

edited by Rolf Ewers

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4257 | Submission Open

Keywords: bioengineering; dental implantology; implant dentistry; dental biomaterials; surface modifications; biomechanics of implant integration; tissue engineering; biocompatibility; implant-associated infections

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

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