Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 3rd Edition

A special issue of Bioengineering (ISSN 2306-5354).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 595

Special Issue Editors


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Guest Editor
Institute for Electromagnetic Sensing of the Environment (IREA), National Research Council, 80124 Napoli, Italy
Interests: electromagnetic bio-effects; bioelectromagnetics; cellular and molecular biology; electroporation; fluorescence and confocal microscopy; mammalian cells exposed to electromagnetic fields in in vitro studies; systematic reviews; electromagnetic fields exposure assessment; biocompatibility of nanomaterials
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute for Electromagnetic Sensing of the Environment (IREA), National Research Council, 80124 Napoli, Italy
Interests: electromagnetic fields; bioelectromagnetics; electromagnetic dosimetry; electroporation; biomedical applications of electromagnetic fields; electromagnetic fields exposure assessment; systematic reviews
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,  

Electric, magnetic, and electromagnetic fields (EMFs) are widely used in everyday life and in specific occupational environments. EMF-based technologies employ different parts of the spectrum, from static fields to low- and high-frequency electromagnetic fields encompassing millimeter waves and THz.  

Exposure to these fields raises concerns about the possible effects on human health, especially due to the diffusion of 5G networks, which are expected to have a major impact on exposure scenarios. On the other hand, biomedical applications of non-ionizing radiation are successfully employed for diagnosis and therapy (e.g., electroporation-based treatments, microwave hyperthermia, etc.). There is great interest in evaluating the associated interaction mechanisms, which are also relevant to foster the development of new biomedical applications or the optimization of the existing ones.  

This Special Issue is open to scientific studies addressing in vitro, in vivo, and epidemiological investigations on electric, magnetic, and electromagnetic exposure aimed at evaluating possible health effects, the beneficial potential of such fields for diagnosis and therapy, and studies focusing on interaction mechanisms. This includes work in any frequency range and covers exposure assessment, dosimetry, risk assessment, communication, and management. Researchers and scholars from industry, academia, and government are invited to submit full research and/or review, systematic review, and meta-analysis papers to this Special Issue.

Dr. Anna Sannino
Dr. Stefania Romeo
Guest Editors

Manuscript Submission Information

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Keywords

  • electromagnetic bio-effects
  • interaction mechanisms
  • environmental health
  • cooperative effects
  • electromagnetic field modelling
  • exposure assessment
  • EMF risk assessment
  • diagnostic and therapeutic applications
  • experimental studies
  • electroporation and electrochemotherapy
  • EMF measurements
  • electromagnetic dosimetry

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Related Special Issue

Published Papers (2 papers)

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Research

15 pages, 1804 KiB  
Article
Neuromuscular Electrical Stimulation Enhances Lower Limb Muscle Synergies During Jumping in Martial Artists Post-Anterior Cruciate Ligament Reconstruction: A Randomized Crossover Trial
by Xiaoyan Wang, Haojie Li and Jiangang Chen
Bioengineering 2025, 12(5), 535; https://doi.org/10.3390/bioengineering12050535 - 16 May 2025
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Abstract
Objective: This study aimed to investigate the effects of neuromuscular electrical stimulation (NMES) on lower limb muscle synergies during the single-leg hop test in martial artists after anterior cruciate ligament (ACL) reconstruction. Methods: Twenty-four martial artists who underwent ACL reconstruction were recruited and [...] Read more.
Objective: This study aimed to investigate the effects of neuromuscular electrical stimulation (NMES) on lower limb muscle synergies during the single-leg hop test in martial artists after anterior cruciate ligament (ACL) reconstruction. Methods: Twenty-four martial artists who underwent ACL reconstruction were recruited and performed a single-leg hop test under two conditions: with NMES (ES) and without NMES (CON). The ES condition involved using Compex SP 8.0 to deliver biphasic symmetrical wave stimulation. Jump performance metrics and electromyographic (EMG) signals were recorded. Muscle synergies of the lower limbs were extracted using non-negative matrix factorization (NMF) to analyze patterns of muscle coordination. Results: Compared with the CON condition, the ES condition significantly reduced the jump time (0.13 ± 0.05 vs. 0.18 ± 0.09; F = 5.660; p = 0.022) and significantly increased the contact time (0.53 ± 0.12 vs. 0.43 ± 0.21; F = 4.013; p = 0.049). Muscle synergy analysis revealed three distinct synergy patterns under both conditions. For synergy pattern 1, compared with the CON condition, the muscle weightings of the rectus femoris and tibialis anterior muscles were significantly increased under the ES condition (p < 0.001). For synergy pattern 2, compared with the CON condition, the muscle weighting of the lateral gastrocnemius muscle was significantly increased under the ES condition (p < 0.001). Additionally, the activation timing of synergy pattern 2 was significantly reduced under the ES condition (p = 0.001). Conclusion: Neuromuscular electrical stimulation enhances jump performance and alters muscle synergy patterns in martial artists after ACL reconstruction. The findings suggest that NMES can promote better lower limb muscle coordination during jumping tasks, potentially aiding in postoperative rehabilitation and performance optimization. Full article
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12 pages, 7441 KiB  
Article
An Evaluation of Magnetic Resonance Imaging Dixon Sequence Fat–Water Separation Techniques (T2w Dixon FSTs) to Detect Dorso-Lumbar Structural Lesions in Patients with Axial Spondyloarthritis
by David Fadli, Pierre-Francois Lintingre, Laurence Dallet, Julien Raoult, Julien Gay-Depassier, Nicolas Bouguennec, Lionel Pesquer and Benjamin Dallaudière
Bioengineering 2025, 12(5), 502; https://doi.org/10.3390/bioengineering12050502 - 9 May 2025
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Abstract
Objective: The aim of this study was to assess and compare the diagnostic accuracy of two MRI techniques for identifying structural bone lesions (fatty lesions [BMFs], subchondral erosions [BMEs], sclerosis [BMS], and ankylosis [A]) in the dorso-lumbar joints. This assessment specifically focused on [...] Read more.
Objective: The aim of this study was to assess and compare the diagnostic accuracy of two MRI techniques for identifying structural bone lesions (fatty lesions [BMFs], subchondral erosions [BMEs], sclerosis [BMS], and ankylosis [A]) in the dorso-lumbar joints. This assessment specifically focused on the application of MRI Dixon sequence fat–water separation techniques (T2w Dixon FSTs) when acquiring T1-weighted (T1w) images as the reference standard, among patients diagnosed with axial spondyloarthritis (SpA). Methods: Conducted at a single center, this study involved the recruitment of patients who underwent both spinal and sacroiliac (SI) joint MRI between 2019 and 2022, with follow-up continuing until 2023. In 2023, three independent readers reassessed the initial MRI datasets to evaluate specific radiological features of SpA. They recorded confidence estimates regarding the use of T2w Dixon FSTs when acquiring T1w images. The centralized MRI interpretations were then compared to established rheumatologic diagnoses. Results: A total of 73 patients (42 men and 31 women) were included in the study. The mean sensitivity, specificity, and accuracy of T2w Dixon FSTs (fat-only images) were at least 75%, 100%, and 96%, respectively, based on the 2023 assessment for all considered items. The diagnostic performance of T2w Dixon FSTs was comparable to that of T1w images. Conclusions: The diagnostic performance of T2w Dixon FSTs (fat-only images) matched that of T1w images not only in assessing structural and fatty lesions, but also in the evaluation of subchondral erosions, sclerosis, and ankylosis in the dorso-lumbar joints of patients with a rheumatologic diagnosis of SpA. These findings suggest the potential avoidance of T1-weighted images when employing multi-parameter, multi-sequence imaging, such as the Dixon sequence. Full article
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