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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Applications of Transcranial Stimulation and EEG-Based Feedback Systems in Bioengineering

edited by Milan Pantovic and

Brach Poston

submission deadline 30 Nov 2025 | Viewed by 73 | Submission Open

Keywords: non-invasive brain stimulation; performance optimization; EEG-based feedback systems; wearable neuromodulation; virtual reality integration

(This special issue belongs to the Section Biosignal Processing)

Cutting-Edge AI Techniques for Enhanced Biomedical Engineering Applications

edited by Avinash Malik and

Alan Wang

submission deadline 30 Nov 2025 | Viewed by 66 | Submission Open

Keywords: deep learning; generative AI; machine learning; precision medicine; biomedical imaging; medical devices; gene therapy; predictive modelling; computational biology; health informatics

(This special issue belongs to the Section Biosignal Processing)

Multimodal Neuroimaging Techniques: Progress and Application, Second Edition

edited by Frédéric Grouiller

submission deadline 30 Nov 2025 | Viewed by 59 | Submission Open

Keywords: multimodal neuroimaging; MRI; MEG; EEG; fNIRS; PET; TMS; VR technology; imaging setups; brain function; multimodal signals processing; deep learning algorithms; artificial intelligence; brain computer interface

(This special issue belongs to the Section Biosignal Processing)

The Use of Artificial Intelligence in Pain Research

edited by

Min Cheol Chang

submission deadline 30 Nov 2025 | Viewed by 58 | Submission Open

Keywords: pain; research; artificial intelligence; deep learning; machine learning

(This special issue belongs to the Section Biosignal Processing)

Advances in Wound Healing and Regenerative Medicine

edited by Sik Namgoong and

Shang-You Yang

submission deadline 30 Nov 2025 | Viewed by 55 | Submission Open

Keywords: wound healing; regenerative medicine; stem cells; tissue engineering; ECM; diabetic ulcers; microsurgical reconstruction; bioactive materials; cell-based therapy; translational models; DNA methylation; CRISPR technology; nanomedicine

(This special issue belongs to the Section Regenerative Engineering)

Novel MRI Techniques and Biomedical Image Processing: Second Edition

edited by Dilbag Singh

submission deadline 30 Nov 2025 | Viewed by 53 | Submission Open

Keywords: MRI; image generation; image processing; image acquisition; image reconstruction; machine learning; deep learning

(This special issue belongs to the Section Biosignal Processing)

Advances in Catheter Ablation of Atrial Fibrillation

edited by

Alexandru Bejinariu

and Obaida Rana

submission deadline 30 Nov 2025 | Viewed by 51 | Submission Open

Keywords: complex arrhythmias; pulmonary vein isolation; pulsed field ablation; electroanatomical mapping

(This special issue belongs to the Section Biosignal Processing)

From Biostatistics to Machine Learning: Modern Approaches in Bioengineering for Modeling and Understanding Biological Complexity

edited by Chien-Wei (Masaki) Lin and Kwang Woo Ahn

submission deadline 1 Dec 2025 | 1 articles | Viewed by 674 | Submission Open

Keywords: statistics; machine learning; AI; computational tools; prediction and classification

(This special issue belongs to the Section Biosignal Processing)

Advancements in Bioreactors for Tissue Engineering

edited by Emma Petiot,

Giovanni Vozzi

and

Shang-Tian Yang

submission deadline 1 Dec 2025 | Viewed by 314 | Submission Open

Keywords: tissue engineering; perfusion bioreactors; bioprocessing; mechanical stimulation; fluid shear stress; oxygen regulation; real-time monitoring; scalable tissue production; computational modeling; smart bioreactors

(This special issue belongs to the Section Regenerative Engineering)

Advanced Physical Techniques in Tissue Engineering and Regenerative Medicine

edited by

Alessandra Giuliani

Michele Furlani

and

Nicole Riberti

submission deadline 10 Dec 2025 | 1 articles | Viewed by 582 | Submission Open

Keywords: tissue engineering; regenerative medicine; advanced imaging modalities; high-resolution microscopy; magnetic resonance imaging (MRI); computed tomography (CT); artificial intelligence (AI)

(This special issue belongs to the Section Regenerative Engineering)

Machine Learning-Aided Medical Image Analysis

edited by

Amirreza Mahbod

and Ramona Woitek

submission deadline 15 Dec 2025 | 4 articles | Viewed by 4826 | Submission Open

Keywords: artificial intelligence; deep learning; machine learning; medical image analysis; medical imaging

(This special issue belongs to the Section Biosignal Processing)

Retinal Biomarkers: Seeing Diseases in the Eye

edited by

Paul Constable

and

Hugo F. Posada-Quintero

submission deadline 15 Dec 2025 | Viewed by 144 | Submission Open

Keywords: biomarker; retina; structure; function; machine learning; deep learning; classification; imaging; electrophysiology

(This special issue belongs to the Section Biosignal Processing)

Tissue Engineering for Regenerative Dentistry, 2nd Edition

edited by

Carlos Fernando Mourão

submission deadline 15 Dec 2025 | Viewed by 61 | Submission Open

Keywords: regenerative dentistry; autologous blood concentrates; platelet-rich fibrin (PRT); stem cells; bioactive biomaterials; tissue engineering; oral and maxillofacial regeneration; extracellular matrix; translational research; dental tissue repair

(This special issue belongs to the Section Regenerative Engineering)

Synthesis, Characterization, and Application of Biomacromolecules and Biobased Polymers

edited by

Shichao Ding

and Wenzhuo Chen

submission deadline 20 Dec 2025 | Viewed by 424 | Submission Open

Keywords: biomacromolecules; biobased polymers; synthesis; characterization; engineered biomaterial; biopharmaceuticals

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Machine Learning in Precision Oncology: Innovations and Applications

edited by Sheida Nabavi and

Jun Bai

submission deadline 20 Dec 2025 | Viewed by 76 | Submission Open

Keywords: generative models in oncology; machine learning in cancer research; large language models in cancer; diffusion models; synthetic medical data; AI-driven cancer diagnosis; deep learning for oncology; personalized cancer therapy; cancer imaging and reconstruction; predictive modeling in oncology; data augmentation in medical imaging; bioinformatics and generative AI; multi-omics integration; digital pathology and AI; computational oncology; clinical decision support systems

(This special issue belongs to the Section Biosignal Processing)

Biomedical Applications of Intelligent Ultrasound Imaging

edited by Guangquan Zhou

submission deadline 25 Dec 2025 | Viewed by 37 | Submission Open

Keywords: artificial intelligence (AI) in ultrasound; deep learning for medical imaging; explainable AI in medical imaging; intelligent ultrasound imaging; AI-powered diagnostics; ultrasound image segmentation; multimodal data fusion (CT/MRI)

(This special issue belongs to the Section Biosignal Processing)

Fetal-Maternal Monitoring during Pregnancy and Labor: Trends and Opportunities

edited by

and

Martin Gerbert Frasch

submission deadline 31 Dec 2025 | 9 articles | Viewed by 33872 | Submission Open

Keywords: fetal monitoring; perinatal medicine; antenatal care; pregnancy; signal processing; artificial intelligence; simulators

(This special issue belongs to the Section Biosignal Processing)

Electromagnetic Regenerative Bioengineering: Updates and Future Directions

edited by

Alfredo Franco-Obregón

submission deadline 31 Dec 2025 | 6 articles | Viewed by 24027 | Submission Open

Keywords: mitochondria; oxidative stress; electromagnetism; ROS (reactive oxygen species); photons; calcium channels; cancer; regenerative medicine

(This special issue belongs to the Section Regenerative Engineering)

Medical Artificial Intelligence and Data Analysis

edited by Ujjwal Baid and Bhakti Baheti

submission deadline 31 Dec 2025 | 7 articles | Viewed by 11053 | Submission Open

Keywords: artificial intelligence; deep learning; medical image classification; medical image segmentation; medical image registration; lesion identification and localization

(This special issue belongs to the Section Biosignal Processing)

Advanced Biomaterials, Coatings, and Techniques: Applications in Medicine

edited by Yong Hou

submission deadline 31 Dec 2025 | 6 articles | Viewed by 10510 | Submission Open

Keywords: biomaterials; coatings; advanced techniques; medical devices; implants; tissue engineering; biocompatibility; 3D printing; nanotechnology; surface modification

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancements in Biomechanical Gait Analysis: Implications for Footwear Biomechanics and Sports Injury Prevention

edited by

Yang Song

Dong Sun

and

Xuanzhen Cen

submission deadline 31 Dec 2025 | 1 articles | Viewed by 6402 | Submission Open

Keywords: human locomotion; motion capture technology; wearable sensors; biomechanical modeling; injury risk assessment; personalized footwear design; machine learning in biomechanics; sports science integration

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Biomechanics of Physical Exercise

edited by

Andrea Biscarini

submission deadline 31 Dec 2025 | 5 articles | Viewed by 6159 | Submission Open

Keywords: biomechanics; kinematics; kinetics; muscle activation; joint loads; proprioception; postural control and balance; neuromotor control; human movement; physical exercise; athletic training; athletic performance; sport; injury prevention; rehabilitation; exercise equipment; equipment design; ergonomics; motion analysis; force plates; electromyography; EMG; musculoskeletal modelling; simulation; sensors; imaging; magnetic resonance; MRI; artificial intelligence; robotics; new technologies

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Biomedical Application of Big Data and Artificial Intelligence—Second Edition

edited by

Yan Pei

and

Jijiang Yang

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5515 | Submission Open

Keywords: artificial intelligence; big data; image processing; data mining; soft computing; bioinformatics; bioengineering; healthcare

(This special issue belongs to the Section Biosignal Processing)

Electric, Magnetic, and Electromagnetic Fields in Biology and Medicine: From Mechanisms to Biomedical Applications: 3rd Edition

edited by

Anna Sannino

and

Stefania Romeo

submission deadline 31 Dec 2025 | 6 articles | Viewed by 4039 | Submission Open

Keywords: electromagnetic bio-effects; interaction mechanisms; environmental health; cooperative effects; electromagnetic field modelling; exposure assessment; EMF risk assessment; diagnostic and therapeutic applications; experimental studies; electroporation and electrochemotherapy; EMF measurements; electromagnetic dosimetry

Recent Advances in the Application of Mathematical and Computational Models in Biomedical Science and Engineering (2nd Edition)

edited by

Sundeep Singh

Roderick Melnik

and Manpreet Singh

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3528 | Submission Open

Keywords: modeling and simulation; biomedical engineering; medical physics; multiphysics and multiscale models; biomedical therapy; neurotechnology; regenerative medicine; drug delivery; data-driven models; machine learning; patient-specific models

(This special issue belongs to the Section Biosignal Processing)

Anaerobic Digestion Advances in Biomass and Waste Treatment

edited by

Tina Kegl

and Breda Kegl

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3506 | Submission Open

Keywords: waste management; biomass and waste pre-treatments; anaerobic digestion; modeling and optimization; biogas plants; biogas production; digestate treatment; microbial fuel cells; electricity production

(This special issue belongs to the Section Biochemical Engineering)

AI and Data Science in Bioengineering: Innovations and Applications

edited by

Muneer Ahmad

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3061 | Submission Open

Keywords: AI; data science; bioengineering; biomedical engineering; predictive modeling; machine learning; smart biomaterials; tissue engineering

(This special issue belongs to the Section Biosignal Processing)

Intelligent Systems for Human Action Recognition

edited by

Mondher Bouazizi

, Yue Yin and Tomoaki Ohtsuki

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2770 | Submission Open

Keywords: wearable sensors; IoT devices; action recognition; computer vision; video analysis; image processing; pattern recognition; human– robot interaction; healthcare; biomedical sensing; biosignal processing; signal processing; activity detection; deep learning; AI

(This special issue belongs to the Section Biosignal Processing)

New Sights of Deep Learning and Digital Model in Biomedicine

edited by

John A. St. Cyr

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2398 | Submission Open

Keywords: deep learning; digital model; biomedicine

(This special issue belongs to the Section Biosignal Processing)

Engineering Neural Motor Control: From Mechanisms to Neural Interfaces

edited by Eizo Miyashita and Yuki Ueyama

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2197 | Submission Open

Keywords: systems neuroscience; computational neuroscience; motor control; motor learning; motor dysfunction; rehabilitation; neuromodulation; human argumentation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Tissue Engineering and Regenerative Medicine Strategies for Biomedical Engineering

edited by Hun Jin Jeong and

Solaiman Tarafder

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2067 | Submission Open

Keywords: tissue engineering; regenerative medicine; bioprinting; microfluidics; tissues on chip

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Label-Free Cancer Detection

edited by

Raphaël Canadas

submission deadline 31 Dec 2025 | 3 articles | Viewed by 1999 | Submission Open

Keywords: label-free; microfluidics; biomarkers; cancer; non-invasive; biosensors; nanotechnology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Smart Applications and Technology for Cardiovascular Disease Management

edited by Alexander Samol and Sven Kaese

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1883 | Submission Open

Keywords: cardiovascular disease; smart applications; technology; wearable devices; artificial intelligence; telemedicine; virtual reality

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

3D Cell Culture Systems: Current Technologies and Applications

edited by

Peggy Stock

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1388 | Submission Open

Keywords: 3D cell culture; tissue engineering; biomaterials; drug discovery; cancer research; regenerative medicine; scaffold technology; high-throughput screening; organoids; in vitro models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Integrative Bioengineering in Orthopedic Surgery: From Regenerative Constructs to Precision Arthroplasty

edited by Man Soo Kim

submission deadline 31 Dec 2025 | 1 articles | Viewed by 859 | Submission Open

Keywords: orthopedic bioengineering; tissue-engineered constructs; stem cell therapy; robotic surgery; AI-guided arthroplasty; smart implants; biomechanical modeling; scaffold-implant hybrid systems; regenerative surgery; precision orthopedics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Nerve Regeneration

edited by Luca Cicero,

Claudia Giampietri

and

Munmun Chattopadhyay

submission deadline 31 Dec 2025 | 1 articles | Viewed by 801 | Submission Open

Keywords: nerve regeneration; neuroengineering; biomaterials; stem cells; neuroprosthetics; biomedical devices

(This special issue belongs to the Section Regenerative Engineering)

Next-Generation Diagnostic and Therapy Systems for Neurodegenerative Diseases

edited by

Raji Sundararajan

and

Miad Faezipour

submission deadline 31 Dec 2025 | 1 articles | Viewed by 770 | Submission Open

Keywords: Alzheimer's disease; Parkinson's disease; machine learning; deep learning; neurostimulation; neuromodulation; artificial intelligence models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Emerging Nanomaterials and Nanotechnologies for Biomedical and Related Applications

edited by

Dipak Maity

and

Mangilal Agarwal

submission deadline 31 Dec 2025 | 1 articles | Viewed by 761 | Submission Open

Keywords: nanomaterials; nanotechnologies; biomedical applications; drug delivery systems; biosensors; tissue engineering; cancer therapeutics; diagnostics; biomedical imaging; photothermal therapy; chemodynamic therapy; cardiovascular diseases; infection control; neurological diseases; orthopedics

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Materials and Methods for Genetic and Cell-Based Therapy for Ocular Tissue

edited by Jesse Sengillo

submission deadline 31 Dec 2025 | Viewed by 652 | Submission Open

Keywords: retinal injury; retinal repair; biomaterials; surgical techniques; drug delivery systems; imaging modalities; stem cell therapy; gene therapy; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Soft and Flexible Sensors for Biomedical Applications

edited by Martina Maselli and Parisa Pour Shahid Saeed Abadi

submission deadline 31 Dec 2025 | Viewed by 195 | Submission Open

Keywords: stretchable electronics; flexible sensors; biomedical applications; wearable devices; conformable materials; health monitoring

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Emerging Roles of Large Language and Foundation Models in Pathology

edited by Zeynettin Akkus

submission deadline 31 Dec 2025 | Viewed by 193 | Submission Open

Keywords: large language models (LLMs); foundation models; digital pathology; histopathology image analysis; self-supervised learning; multi-modal AI; clinical decision support; retrieval-augmented generation (RAG); explainable AI (XAI); translational pathology

(This special issue belongs to the Section Biosignal Processing)

Bio-Scaffold Engineering for Soft Tissue Regenerative Medicine

edited by Zhonggang Feng

submission deadline 31 Dec 2025 | Viewed by 186 | Submission Open

Keywords: bio-scaffold engineering; decellularization; 3D bio-printing; hydrogel; polymer; natural materials; electrospinning; mechanical environment; cellular homeostasis; simulation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Biotechnology and Applied Microbiology

edited by

Ranjith Kumar Manoharan

and

Sathiyaraj Srinivasan

submission deadline 31 Dec 2025 | Viewed by 186 | Submission Open

Keywords: probiotics; postbiotics; biofilms; antimicrobial resistance; multidrug-resistant bacteria; genomics; microbiome; functional foods

(This special issue belongs to the Section Biochemical Engineering)

Cardiac Tissue Engineering: From Tissue Regeneration to In Vitro Tissue Models

edited by

Elisabetta Rosellini

and Laurie Boyer

submission deadline 31 Dec 2025 | Viewed by 183 | Submission Open

Keywords: cardiac tissue engineering; heart-on-a-chip; stem cell therapy

(This special issue belongs to the Section Regenerative Engineering)

Advances and Applications of Neuroimaging

edited by Richard James Addante and Sujoy Ghosh-Hajra

submission deadline 31 Dec 2025 | Viewed by 182 | Submission Open

Keywords: neuroimaging; fMRI; EEG; ERPs; TMS; tDCS; tACS; rTMS; MRI; PET; iEEG; sEEG

(This special issue belongs to the Section Biosignal Processing)

Advancements in Imaging and Sensing of Single Multi-Functional Nanoparticles, Viruses and Organelles

edited by Michelle A. Digman, Qimei Zhang, Jian Yang and

Georgios Alexandrakis

submission deadline 31 Dec 2025 | Viewed by 121 | Submission Open

Keywords: super-resolution microscopy; hyperspectral imaging; nanopore sensing; plasmonics; lipid nanoparticles; liposomes; quantum dots; virus; cell organelles

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Novel Strategies in Dentin/Pulp Regeneration Through Tissue Engineering

edited by Roda Seseogullari-Dirihan

submission deadline 31 Dec 2025 | Viewed by 117 | Submission Open

Keywords: dentin/pulp regeneration; stem cell; tissue engineering; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Voice Analysis Techniques for Medical Diagnosis

edited by

Shinichi Tokuno

and

Antonio Lanata

submission deadline 31 Dec 2025 | Viewed by 100 | Submission Open

Keywords: voice biomarker; diagnosis; monitoring; severity assessment

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Brain Stimulation Technology

edited by

Paolo Belardinelli

and

Giulia Liberati

submission deadline 31 Dec 2025 | Viewed by 93 | Submission Open

Keywords: brain stimulation; state-dependent brain stimulation; brain disorders; deep brain stimulation; transcranial magnetic stimulation; transcranial electrical stimulation; temporal interference stimulation

(This special issue belongs to the Section Biosignal Processing)

Machine Learning-Driven Innovations in Predictive Healthcare

edited by