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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Papers in Biomedical Engineering and Biomaterials

edited by

Andrea Cataldo

Christian Demitri

and

Emanuele Piuzzi

submission deadline 30 Apr 2025 | 11 articles | Viewed by 48272 | Submission Open

Keywords: development; design and characterization of biomaterials; biological tissues and bio-systems; bioengineering; medical diagnosis; biosensors; devices; lab-on-chip and organ-on-a-chip; biomedical instrumentation; smart sensing and predictive modelling; Industry-4.0-ehanced biomedical systems

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Bone Repair and Regeneration

edited by

Jianhua Li

submission deadline 30 Apr 2025 | 11 articles | Viewed by 33125 | Submission Open

Keywords: biomaterials; bone scaffold; bone tissue engineering; osteogenesis; regenerative medicine; bone immunoregulation; antibacterial bone scaffold; bone implant; bone defect treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Polyhydroxyalkanoate (PHA) Production, 4th Edition

edited by

Martin Koller

submission deadline 30 Apr 2025 | 7 articles | Viewed by 21944 | Submission Open

(This special issue belongs to the Section Biochemical Engineering)

Smartphone- or Tablet-Based Technologies for Balance and Gait Rehabilitation

edited by

Beom-Chan Lee

submission deadline 30 Apr 2025 | 7 articles | Viewed by 17280 | Submission Open

Keywords: smartphone- or tablet-based technologies for balance and gait rehabilitation; exergame; diagnostic tools for balance and gait impairments; wearable sensors; telerehabilitation or telemonitoring; sensory biofeedback; aging or neurological disorders

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Tissue Engineering for Regenerative Dentistry

edited by

Shahram M. Ghanaati

and

Carlos Fernando Mourão

submission deadline 30 Apr 2025 | 8 articles | Viewed by 14349 | Submission Open

(This special issue belongs to the Section Regenerative Engineering)

Advances in Additive Manufacturing Technologies in the Clinical, Pharmaceutical and Biomedical Sectors

edited by

Karthik K. Tappa

and

Udayabhanu Jammalamadaka

submission deadline 30 Apr 2025 | 6 articles | Viewed by 13660 | Submission Open

Keywords: 3D printing; bioprinting; bioactive materials; bioink; anatomical models; surgical guides; patient-specific implants; 3D-printed drug delivery systems; 3D-printed biomedical devices

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Machine Learning and Deep Learning Applications in Healthcare

edited by

Jorge Mateo

and

Ana María Torres Aranda

submission deadline 30 Apr 2025 | 7 articles | Viewed by 11319 | Submission Open

Keywords: machine learning; deep learning; big-data enabled healthcare systems; biomedical diagnostic techniques; diagnostic imaging; medical decision making; digital pathology; digital radiology; artificial neural networks; artificial intelligence; smart health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Intelligent Health Management, Nursing and Rehabilitation Technology

edited by Ning Deng

submission deadline 30 Apr 2025 | 5 articles | Viewed by 10266 | Submission Open

Keywords: intelligent rehabilitation technology; health monitoring systems; machine learning in healthcare; intelligent nursing technology; data-driven health management

(This special issue belongs to the Section Biosignal Processing)

Biomedical Imaging and Data Analytics for Disease Diagnosis and Treatment, 2nd Edition

edited by

Cosimo Ieracitano

and

Xuejun Zhang

submission deadline 30 Apr 2025 | 13 articles | Viewed by 9979 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; biomedical engineering; medical image processing; data analytics

(This special issue belongs to the Section Biosignal Processing)

Advances in Physical Therapy and Rehabilitation

edited by

Alvaro N. Gurovich

submission deadline 30 Apr 2025 | 6 articles | Viewed by 8719 | Submission Open

Keywords: biomedical engineering; rehabilitation engineering; biomechanics; motor control; applied physiology; 3D printing; additive manufacture; imaging; ultrasound

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Biomedical Imaging and Biomedical Signal Processing

edited by Zvi Friedman

submission deadline 30 Apr 2025 | 4 articles | Viewed by 7361 | Submission Open

Keywords: artificial intelligence; biomedical imaging; biomedical signal processing; machine learning; deep learning; image segmentation; image classification; image retrieval; knowledge extraction

(This special issue belongs to the Section Biosignal Processing)

Adaptive Neurostimulation: Innovative Strategies for Stimulation

edited by

Luca Mesin

submission deadline 30 Apr 2025 | 3 articles | Viewed by 7274 | Submission Open

Keywords: neurostimulation; closed-loop stimulation; adaptive stimulation; sustained attention; working memory; meditation; relaxation; stress; mindfulness; epilepsy; psychiatric disorders; ADHD; transcranial direct current stimulation; transcranial alternating current stimulation; binaural beats; light pulse stimulation; EEG; ECG; pupillogram; breath monitoring; real time processing; EEG rhythms; complexity; entropy; heart rate variability

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Polymeric Biomaterials for Wound Healing Applications

edited by

Shangyou Yang

submission deadline 30 Apr 2025 | 3 articles | Viewed by 6880 | Submission Open

Keywords: polymeric biomaterials; wound healing; scaffolds; dressings; coatings; tissue regeneration; tissue engineering; biocompatibility; biodegradability; controlled release

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanics of Sports Injuries

edited by Man Soo Kim and Sue En Sohn

submission deadline 30 Apr 2025 | 4 articles | Viewed by 6474 | Submission Open

Keywords: sports; shoulder; knee; spine; hip; ankle; wrist; elbow; muscle; mechanics

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advances in Biomedical Analytics: Real-World Evidence, Digital Health, Robotics and Artificial Intelligence

edited by

Kelly H. Zou

, Susan Halabi, Aaron Galaznik and Kiyoyuki Chinzei

submission deadline 30 Apr 2025 | 2 articles | Viewed by 6115 | Submission Open

Keywords: real-world data; real-world evidence; big data; randomized controlled trials; patient-reported outcomes; digital innovation; digital health; robotics; medical devices; artificial intelligence; machine learning; deep learning

(This special issue belongs to the Section Biosignal Processing)

10th Anniversary of Bioengineering: Biosignal Processing

edited by

Andrea Cataldo

Francesco Amato

and Raissa Schiavoni

submission deadline 30 Apr 2025 | 5 articles | Viewed by 5793 | Submission Open

Keywords: biosignal processing; signal analysis; biomedical devices; medical diagnostics; biomedical imaging; biomedical engineering; health monitoring; wearable systems; image processing and visualization; biosensor technology; biosensors; lab-on-chip and organ-on-a-chip instrumentation; smart sensing and predictive modeling; 4.0-ehanced biomedical systems

(This special issue belongs to the Section Biosignal Processing)

Fundamentals of Orthopaedic Biomechanics: Implants, AI, and Innovation in Surgery

edited by Farid Amirouche

submission deadline 30 Apr 2025 | 3 articles | Viewed by 5294 | Submission Open

Keywords: orthopedics; biomechanics; implants; shoulder; knee; hip; hand and motion analysis; AI; augmented reality; ortho innovation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Multimodal Imaging Methodologies and Virtual/Augmented Reality for Biomedical Applications

edited by

Vera Gramigna

and Arrigo Palumbo

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4531 | Submission Open

Keywords: multimodal imaging; magnetic resonance imaging (MRI); computerized tomography (CT); positron emission tomography (PET); single-photon emission computed tomography (SPECT); functional near infrared spectroscopy (fNIRS); virtual; augmented; and mixed reality; biomedicine; human– robot interaction; technology in healthcare

(This special issue belongs to the Section Biosignal Processing)

Advanced Assessment of Medical Devices

edited by Andrew Robert Beadling, Michael Bryant and Richard M. Hall

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4451 | Submission Open

Keywords: medical devices; preclinical assessment; biomaterials; bioengineering; regulatory science; digital twins

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

ML and AI for Augmented Biosensing Applications

edited by

Rossana Madrid

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4042 | Submission Open

(This special issue belongs to the Section Biosignal Processing)

Natural Peptides/Proteins and Their Applications in Bioengineering

edited by

Satish Rojekar

and Anusha Rani Pallapati

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3814 | Submission Open

Keywords: peptide design; protein engineering; biomaterial fabrication; drug delivery systems; tissue regeneration; bioengineering; biomaterials; biomedical application

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Biomedical Diagnosis and Prognosis: Second Edition

edited by

Tae-Seong Kim

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3768 | Submission Open

Keywords: medical diagnosis; medical prognosis; medical AI; machine learning; deep learning; pervasive AI medical systems

(This special issue belongs to the Section Biosignal Processing)

Computer-Aided Diagnosis for Biomedical Engineering

edited by

Brij Gupta

Nadia Nedjah

and

Kwok Tai Chui

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3009 | Submission Open

Keywords: computer-aided diagnosis; biomedical engineering; secure biomedical; machine learning; deep learning; image processing; medical imaging; clinical decision support systems

(This special issue belongs to the Section Biosignal Processing)

Machine Learning Methods for Biomedical Imaging

edited by Lei Qiu, Yibo Xie and Suk Whan Yoon

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2486 | Submission Open

Keywords: AI; machine learning; deep learning; biomedical image analysis

(This special issue belongs to the Section Biosignal Processing)

Waste-to-Resource: Microbial-Driven Processes for Gaseous, Liquid and Solid Wastes Valorization

edited by Valeria Agostino, Annalisa Abdel Azim and Nicolò S. Vasile

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2424 | Submission Open

Keywords: waste-to-resource; CO2 valorization; industrial waste streams valorization; bio-based manufacturing; acetogens; microalgae; methanogens; methanotrophs; fermentation

(This special issue belongs to the Section Biochemical Engineering)

Research Progress in Stem Cells and Regenerative Medicine

edited by

Naoki Yamamoto

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2102 | Submission Open

Keywords: regenerative medicine; cancer therapy; culture method; drug screening; alternative methods of animal experiment

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Connective Tissue Structure and Function in Normal, Pathological and Aging Skin

edited by Agata Jabłońska-Trypuć

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1648 | Submission Open

Keywords: connective tissue; skin; fibroblasts; collagen; ECM; aging

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Engineering Cells for Immunotherapy

edited by Yun Chang

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1566 | Submission Open

Keywords: cell engineering; CAR T cells; immunotherapy; genetically modified immune cells; tumor targeting; synthetic biology; biomaterials for cell therapy; gene editing for immunotherapy; delivery systems; molecular immunoengineering; preclinical and clinical immunotherapies

(This special issue belongs to the Section Regenerative Engineering)

Advancements in Tissue-Engineered Muscle

edited by Filiz Ates

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1349 | Submission Open

Keywords: skeletal muscle; tissue engineering; biomaterial scaffolds; contractile force; myoblasts; satellite cells; stem cells; volumetric muscle loss; muscle regeneration; myogenic differentiation; vascularization; organ-on-chip; nanofibers; 3D printing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Cell Mechanobiology in Health and Disease

edited by Sangyoon Han

submission deadline 30 Apr 2025 | Viewed by 649 | Submission Open

Keywords: mechanobiology; fibroblasts; immune cells; stem cells; cancer cells; connective tissue disorder; extracellular matrix; shear stress sensing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Systems in Radiotherapy

edited by

Rosario Megna

and Marcello Serra

submission deadline 30 Apr 2025 | 1 articles | Viewed by 569 | Submission Open

Keywords: innovative techniques; cancer treatment; radiation therapy

(This special issue belongs to the Section Biosignal Processing)

Microfluidic Devices for Biomedical Engineering

edited by Therese W. Herling

submission deadline 30 Apr 2025 | Viewed by 279 | Submission Open

Keywords: microfluidics; lab-on-a-chip; organ-on-a-chip; diagnostics; microfabrication; biomedical analysis; biomarker detection; biomolecular analysis and characterization; biomolecular separation; microdroplets; microreactors; detection and optics; single-cell analysis; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Electrical Stimulation Systems for Cardiac Tissue Engineering

edited by Johannes Muller

submission deadline 30 Apr 2025 | Viewed by 181 | Submission Open

Keywords: electrical stimulation; cardiac tissue engineering; myocardial regeneration; biomaterial scaffolds; electrode design; tissue maturation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Emerging Trends in Materials for Advanced Biosensing and Biomedical Applications

edited by Xuan Luo

submission deadline 30 Apr 2025 | Viewed by 176 | Submission Open

Keywords: biosensing; biomedical applications; novel materials; nanomaterials; biocompatibility; sustainability

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Vascular Interventions and Their Techniques

edited by Elias Kehayas

submission deadline 1 May 2025 | Viewed by 293 | Submission Open

Keywords: vascular interventions; vascular procedures; vascular surgery; endovascular techniques; minimally invasive vascular procedures; interventional radiology; angioplasty; stenting; embolization; thrombolysis; atherectomy; intravascular lithoplasty; thrombectomy; vascular access techniques; catheterization; vascular imaging; vascular interventions for peripheral artery disease

(This special issue belongs to the Section Regenerative Engineering)

Innovations in Biomaterials for Advanced Biomedical Applications

edited by

Muhammad Zubair

and

Aman Ullah

submission deadline 15 May 2025 | 1 articles | Viewed by 612 | Submission Open

Keywords: biomaterials; cancer treatment; wound care; cancer therapy; nanomedicine; drug delivery; tumor targeting; biocompatible materials; theranostics; immunotherapy; drug-release systems

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Medical Artificial Intelligence and Data Analysis

edited by Ujjwal Baid and Bhakti Baheti

submission deadline 30 May 2025 | 4 articles | Viewed by 5885 | Submission Open

Keywords: artificial intelligence; deep learning; medical image classification; medical image segmentation; medical image registration; lesion identification and localization

(This special issue belongs to the Section Biosignal Processing)

Transformative Approaches in Musculoskeletal Tissue Regeneration: From Bench to Bedside

edited by

Jiabing Fan

submission deadline 30 May 2025 | Viewed by 151 | Submission Open

Keywords: musculoskeletal tissue regeneration; MSC-mediated therapies biomaterial delivery chronic bone loss disorders degenerative diseases musculoskeletal injuries

(This special issue belongs to the Section Regenerative Engineering)

Brain Computer Interfaces for Motor Control and Motor Learning

edited by

Ramana Kumar Vinjamuri

submission deadline 30 May 2025 | Viewed by 122 | Submission Open

Keywords: brain-computer interface (BCI); motor control; motor learning; AI and ML in BCIs; neuroprosthetics; neurorehabilitation

(This special issue belongs to the Section Biosignal Processing)

Fetal-Maternal Monitoring during Pregnancy and Labor: Trends and Opportunities

edited by

and

Martin Gerbert Frasch

submission deadline 31 May 2025 | 8 articles | Viewed by 28389 | Submission Open

Keywords: fetal monitoring; perinatal medicine; antenatal care; pregnancy; signal processing; artificial intelligence; simulators

(This special issue belongs to the Section Biosignal Processing)

Machine Learning and Medicine: The Interface of Medicine, Engineering and Artificial Intelligence

edited by Simon W. Rabkin

submission deadline 31 May 2025 | 8 articles | Viewed by 19531 | Submission Open

Keywords: medical informatics; healthcare analytics; predictive modeling; digital health; precision medicine; machine learning; artificial intelligence

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence and Machine Learning in Spine Research

edited by

Min Cheol Chang

submission deadline 31 May 2025 | 7 articles | Viewed by 14156 | Submission Open

Keywords: spinal disorder; artificial intelligence; machine learning

(This special issue belongs to the Section Biosignal Processing)

Application of Deep Learning in Medical Diagnosis

edited by

Zhanlin Ji

and

Li Zhao

submission deadline 31 May 2025 | 7 articles | Viewed by 10995 | Submission Open

Keywords: deep learning; artificial intelligence; medical image segmentation; medical image target detection; medical image classification; computer-assisted therapy

(This special issue belongs to the Section Biosignal Processing)

Functionalization of Dental Materials towards Improved Interaction with the Oral Environment

edited by

Nicoleta Ilie

and

Andrei Cristian Ionescu

submission deadline 31 May 2025 | 4 articles | Viewed by 10815 | Submission Open

Keywords: resin composites; bioreactors; oral biofilms; microbial adherence; biofilm formation; bioactivity; controlled release; toxicity; surface texturing; surface characterization; aging; accelerated aging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Drug Delivery Systems for Cancer Treatment

edited by

Wujie Zhang

submission deadline 31 May 2025 | 3 articles | Viewed by 10054 | Submission Open

Keywords: drug delivery; cancer treatment; controlled release; sustained release; drug targeting; microcarrier; nanocarrier; tumor microenvironment-responsive; cancer stem-like cells

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Joint Biomechanics and Implant Design

edited by Ryan Willing

submission deadline 31 May 2025 | 8 articles | Viewed by 7285 | Submission Open

Keywords: orthopedics; sports medicine; arthroplasty; prosthesis design; finite element analysis; joint motion simulators; imaging; contact mechanics; instability; loosening

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advancements in Artificial Intelligence for Wearable Devices: A New Perspective on Healthcare Applications

edited by

Maria Giovanna Bianco

Salvatore Pullano

and

Syed Kamrul Islam

submission deadline 31 May 2025 | 3 articles | Viewed by 6840 | Submission Open

Keywords: wearable devices; artificial lntelligence; machine learning; biomedical signal processing; deep learning; bio-inspired systems; biosensor devices

(This special issue belongs to the Section Biosignal Processing)

Novel, Low Cost Technologies for Cancer Diagnostics and Therapeutics

edited by

Brian T. Crouch

and

Jenna Mueller

submission deadline 31 May 2025 | 3 articles | Viewed by 6269 | Submission Open

Keywords: low-cost cancer diagnostics; low-cost cancer therapeutics; point-of-care technology; see and treat; global health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomedical Applications of Optical Coherence Tomography, Second Edition

edited by Shintaro Horie

submission deadline 31 May 2025 | 3 articles | Viewed by 5997 | Submission Open

Keywords: retinal imaging; optical coherence tomography; optics; biophotonics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomedical Application of Big Data and Artificial Intelligence—Second Edition

edited by

Yan Pei

and

Jijiang Yang

submission deadline 31 May 2025 | 2 articles | Viewed by 3885 | Submission Open

Keywords: artificial intelligence; big data; image processing; data mining; soft computing; bioinformatics; bioengineering; healthcare

(This special issue belongs to the Section Biosignal Processing)

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