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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Preclinical Models in Cardiovascular Disease Research

edited by

Muhammad Riaz

submission deadline 31 Mar 2026 | Viewed by 100 | Submission Open

Keywords: cardiovascular diseases; preclinical cell models; preclinical animal models; iPSCs; organ-on-chip; computational models

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

AI in Biomedical Image Segmentation, Processing and Analysis

edited by

Toufique Ahmed Soomro

Lihong Zheng

and Mohammad Ali Moni

submission deadline 31 Mar 2026 | Viewed by 93 | Submission Open

Keywords: artificial intelligence; biomedical imaging; image segmentation; deep learning; medical image processing; radiomics; explainable AI; computer-aided diagnosis

(This special issue belongs to the Section Biosignal Processing)

Gene Therapies for Regenerative Medicine

edited by

Eddie Han Pin Tan

and

Yie Hou Lee

submission deadline 31 Mar 2026 | Viewed by 60 | Submission Open

Keywords: cell therapy; gene therapy; regenerative medicine; gene delivery; stem cell engineering; tissue engineering; biomaterials; cell reprogramming; viral vectors

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Electromechanical Effects in Biomedical Science: Mechanisms, Materials, and Medical Applications

edited by

Melika Mohammadkhah

Dragan Marinkovic

and

Paula Pascoal-Faria

submission deadline 31 Mar 2026 | Viewed by 43 | Submission Open

Keywords: electromechanical effects; piezoelectricity; flexoelectricity; bone remodeling and regeneration; mechanobiology; regenerative medicine; smart biomaterials; tissue engineering; biomedical applications; electroactive scaffold; computational modeling of coupled effects; experimental identification of electromechanical effects in tissues; smart drug delivery systems; bioelectronic medicine; smart medical technology; digital twin models for tissue engineering applications

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Biomedical Engineering Strategies for Scoliosis Treatment

edited by Pier Francesco Costici and Sergio De Salvatore

submission deadline 31 Mar 2026 | Viewed by 35 | Submission Open

Keywords: scoliosis; AIS; gait analysis; posture analysis; spine surgery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Tissue Engineering and Next-Generation Biomaterials: From Techniques to Emerging Applications

edited by

Yageng Li

, Nazlı Tümer and Pedro J. Díaz-Payno

submission deadline 31 Mar 2026 | Viewed by 35 | Submission Open

Keywords: tissue engineering; regenerative medicine; biomedical engineering; advanced biomaterials; biofabrication

(This special issue belongs to the Section Regenerative Engineering)

Diagnostic Biomedical Image and Processing with Artificial Intelligence and Deep Learning—2nd Edition

edited by

Hongying Meng

and Xinrong Chen

submission deadline 31 Mar 2026 | Viewed by 34 | Submission Open

Keywords: biomedical image; artificial intelligence; deep learning; image processing; medical imaging; computer-assisted diagnosis; pattern recognition; computer vision; bioengineering; medical large language models

(This special issue belongs to the Section Biosignal Processing)

Stem Cell Immunoengineering

edited by Yun Chang

submission deadline 31 Mar 2026 | Viewed by 31 | Submission Open

Keywords: stem cell; immunoengineering; immune cells; genetic and epigenetic programming; biomaterials; delivery system

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advances in Polymer Biotechnology: Sustainable Materials, Biocatalysis, and Industrial Applications

edited by

José Cleiton Sousa dos Santos

and Leonardo Farias Serafim

submission deadline 31 Mar 2026 | Viewed by 29 | Submission Open

Keywords: polymer biotechnology; sustainable materials; biocatalysis; bio-based polymers; biomanufacturing; smart materials; polymer nanocomposites; industrial biotechnology

(This special issue belongs to the Section Biochemical Engineering)

Advanced Fermentation Technologies for Value-Added Production

edited by

Jiahua Shi

submission deadline 31 Mar 2026 | Viewed by 28 | Submission Open

Keywords: food waste; bioconversion; fermentation technology; value-added products; sustainable food system; microbial system; process optimization

(This special issue belongs to the Section Biochemical Engineering)

Biomaterials for Cartilage and Bone Tissue Engineering: Third Edition

edited by

Francesca Scalera

submission deadline 31 Mar 2026 | Viewed by 21 | Submission Open

Keywords: cartilage; bone; scaffolds; stem cells; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Restoring Form and Function: Clinical Frontiers in Regenerative Applications

edited by

Joris A. van Dongen

Steven Paul Nisticò

, Luigi Bennardo and Marco Marcasciano

submission deadline 31 Mar 2026 | Viewed by 18 | Submission Open

Keywords: regenerative medicine; plastic and reconstructive surgery; tissue; traumatic injuries; tissue regeneration; wound healing

(This special issue belongs to the Section Regenerative Engineering)

Multiscale PDE–Agent-Based Modeling in Health and Disease

edited by

José Alberto Rodrigues

and

Jacinta Serpa

submission deadline 31 Mar 2026 | Viewed by 17 | Submission Open

Keywords: PDE; reaction– diffusion; agent-based model; angiogenesis; chemotaxis; Turing pattern; perfusion heterogeneity; pharmacokinetics; multiscale modeling; data assimilation

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Plastic and Reconstructive Surgery: Innovations and Clinical Applications

edited by Cesar Abraham Gomez-Cabello and

Antonio Jorge Forte

submission deadline 13 Apr 2026 | Viewed by 112 | Submission Open

Keywords: artificial intelligence; machine learning; plastic surgery; reconstructive surgery; surgical planning; risk stratification; outcome prediction; postoperative monitoring

(This special issue belongs to the Section Biosignal Processing)

Smart Polymer Hydrogels for Advanced Biomedical Applications

edited by

Yongfeng Gao

submission deadline 20 Apr 2026 | Viewed by 18 | Submission Open

Keywords: smart hydrogels; stimuli-responsive polymers; drug delivery systems; tissue engineering; regenerative medicine; biosensors; biocompatibility; controlled release; biomedical materials; supramolecular hydrogels

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Tendon/Ligament and Enthesis Injuries: Repair and Regeneration

edited by Dai Fei Elmer Ker, Jingyu Shi and Bingyang Dai

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2260 | Submission Open

Keywords: tendon; ligament; enthesis; drug delivery; therapeutics; biomaterials; tissue engineering; musculoskeletal animal models

(This special issue belongs to the Section Regenerative Engineering)

Basics and Mechanisms of Different Neuromodulation Devices

edited by

Alaa Abd-Elsayed

submission deadline 30 Apr 2026 | Viewed by 50 | Submission Open

Keywords: spinal cord stimulation; peripheral nerve stimulation; deep brain stimulation; vagal nerve stimulation; gastric stimulators; sacral stimulators; neuromodulation; basics; mechanism of action

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Ophthalmic Engineering: Fourth Edition

edited by

Xiaofei Wang

submission deadline 30 Apr 2026 | Viewed by 22 | Submission Open

Keywords: ophthalmology; biomechanics; eye; medical imaging; optical coherence tomography; artificial intelligence; deep learning; virtual reality; medical device; finite element method; inverse analysis

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Biodegradable-Implant Materials, 3rd Edition

edited by

Hamdy Ibrahim

submission deadline 30 Apr 2026 | Viewed by 14 | Submission Open

Keywords: biomaterials; bioprinting; additive manufacturing; biocompatibility

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Innovative Tools for Muscular Assessment

edited by Ross Alan Bogey

submission deadline 30 Apr 2026 | Viewed by 10 | Submission Open

Keywords: muscle force; muscle power; sarcopenia; muscle function; aging and atrophy

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Biotechnology

edited by Mohammad (Behdad) Jamshidi and Omid Moztarzadeh

submission deadline 20 May 2026 | Viewed by 180 | Submission Open

Keywords: artificial intelligence (AI); biotechnology; machine learning; deep learning; digital twins; multi-omics integration; cancer diagnostics; synthetic biology; internet of bio-nano things (IoBNT); drug discovery

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Biomedical Diagnosis and Prognosis: Third Edition

edited by

NIkolaos Papandrianos

and

Ioannis D. Apostolopoulos

submission deadline 30 May 2026 | Viewed by 28 | Submission Open

Keywords: medical diagnosis; medical prognosis; medical AI; machine learning; deep learning; pervasive AI medical systems

(This special issue belongs to the Section Biosignal Processing)

New Sights of Data Analysis and Digital Model in Biomedicine

edited by

Robert Karpiński

submission deadline 31 May 2026 | Viewed by 468 | Submission Open

Keywords: artificial intelligence in medicine; machine learning for diagnosis; deep learning in medical imaging; predictive analytics in healthcare; AI-powered clinical decision support; natural language processing in biomedicine; data-driven disease diagnosis; digital twins in healthcare; big data in biomedical diagnostics; AI-enhanced biomarker discovery

(This special issue belongs to the Section Biosignal Processing)

Advances in Neural Interface Techniques and Applications

edited by

Lei Chen

and

Yi Wang

submission deadline 31 May 2026 | Viewed by 47 | Submission Open

Keywords: neural interface; brain machine interface; neural recording and stimulation; neural signal processing; flexible electronics; implantable bioelectronics; surgical implantation; neural prosthetics; neurological diseases and treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Biomedical Engineering Applications Towards Clinical Translation

edited by

Shivaram Poigai Arunachalam

submission deadline 31 May 2026 | Viewed by 28 | Submission Open

Keywords: artificial intelligence (AI); bioengineering; clinical translation; medical imaging; digital twins; precision medicine; digital health; explainable AI (XAI)

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Wearable Sensors for Human Gait Analysis

edited by

Tong Li

, Qingguo Li and Bingfei Fan

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1496 | Submission Open

Keywords: wearable sensors; human movement analysis; rehabilitation; sport science; sensor fusion; machine learning

(This special issue belongs to the Section Biosignal Processing)

Advances in Computational Imaging and Artificial Intelligence for Biomedical and Clinical Applications

edited by Nan Meng,

Jason Pui Yin Cheung

and Junming Shao

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1426 | Submission Open

Keywords: computational imaging; artificial intelligence; deep learning; medical image analysis; medical diagnosis

(This special issue belongs to the Section Biosignal Processing)

The Biophysics of Vocal Onset, 2nd Edition

edited by

Sten Ternström

and

Claudia Manfredi

submission deadline 30 Jun 2026 | Viewed by 25 | Submission Open

Keywords: biophysics; vocal onset; intraglottal pressure; transglottal flow; glottal area; intraglottal turbulence; videokymography; glottography; high-speed imaging; voice acoustics; voice synthesis; machine learning

(This special issue belongs to the Section Biosignal Processing)

Novel Microfluidics Applications in Dental, Oral, and Craniofacial Research

edited by

Xianrui Yang

, Jing Pan, Fan Zhang and

L. Shannon Holliday

submission deadline 3 Jul 2026 | Viewed by 113 | Submission Open

Keywords: dentistry; microfluidics; stem cells; bioengineering; biological mechanisms

AI and Data Analysis in Neurological Disease Management

edited by