Neuroscience of Cognition and Motor Control

A Special Issue of Behavioral Sciences (ISSN 2076-328X) belonging to the section "Experimental and Clinical Neurosciences".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 350

Editor


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Guest Editor
Department of Psychology, The American College of Greece, 153 42 Athens, Greece
Interests: cognitive and behavioral neuroscience; cholinergic system; cognitive function; motor function; mental health

Special Issue Information

Dear Colleagues,

This Special Issue on Neuroscience of Cognition and Motor Control explores the neural mechanisms underlying human motor behavior and its interaction with cognitive processes. Recent advances in human research, employing neuroimaging, electrophysiology, and computational modeling, have revealed that cognition and motor control are deeply interconnected. Studies highlight shared neural circuits spanning the cortex, basal ganglia, and cerebellum, underscoring the integrated organization of these systems. This Special Issue focuses on how cognitive domains—including perception, attention, memory, and decision-making—influence motor planning, execution, and learning in humans. It also examines the reciprocal effects, showing how motor experience shapes cognitive functions through feedback mechanisms and neural plasticity. Bridging both fundamental and applied perspectives, the collection addresses the pathophysiology of cognitive-motor disorders and explores innovative strategies for human cognitive–motor rehabilitation. By integrating insights across neuroscience, psychology, and clinical practice, the Special Issue advances our understanding of how the human brain orchestrates the dynamic interplay between cognition and movement, offering new avenues for therapeutic interventions in neurological and psychiatric conditions.

Dr. Eleni Konsolaki
Guest Editor

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Keywords

  • cognitive–motor integration
  • perception–action coupling
  • executive function
  • sensorimotor processing
  • motor learning and adaptation
  • cortico-basal ganglia-cerebellar networks
  • cognitive–motor rehabilitation
  • neural plasticity
  • brain connectivity
  • decision-making

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Published Papers (1 paper)

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Research

14 pages, 959 KB  
Article
Neural Correlates of Uncertainty Processing During Decision-Making in Individuals with Different Levels of Worry Proneness
by Xueli Cai, Mengxue Wu, Hong Tang, Rui Yang and Ju Fan
Behav. Sci. 2026, 16(9), 1518; https://doi.org/10.3390/bs16091518 - 28 Aug 2026
Abstract
Background: Worry proneness has been proposed to influence uncertainty processing; however, its neural mechanisms during different forms of uncertain decision-making remain poorly understood. This study used functional magnetic resonance imaging (fMRI) to investigate behavioral and neural responses associated with risky and ambiguous decision-making [...] Read more.
Background: Worry proneness has been proposed to influence uncertainty processing; however, its neural mechanisms during different forms of uncertain decision-making remain poorly understood. This study used functional magnetic resonance imaging (fMRI) to investigate behavioral and neural responses associated with risky and ambiguous decision-making and to examine how individual differences in worry proneness relate to uncertainty-related neural processing. Methods: Participants completed a modified ambiguity–risk decision-making task during fMRI scanning. Whole-brain, region-of-interest (ROI), and continuous PSWQ-based correlation analyses were conducted to characterize neural responses associated with uncertainty type and individual differences in worry proneness. Results: Behavioral analyses revealed no significant effects of worry proneness or uncertainty type on gambling choices or reaction times. Whole-brain analyses showed that risky decisions elicited greater activation than ambiguous decisions in the right insula, right inferior parietal lobule, and left supramarginal gyrus, whereas ambiguous decisions preferentially recruited the right superior temporal gyrus. An exploratory peak-level interaction between worry proneness and uncertainty type was identified in the right middle frontal gyrus (BA6), with higher worry proneness associated with lower BA6 activation during risky decision-making. Continuous analyses further showed that BA6 activation during risky decisions was negatively correlated with PSWQ scores. ROI analyses demonstrated greater activation during risky than ambiguous decisions in the bilateral caudate nucleus, left insula, and right inferior frontal gyrus. Conclusions: These findings demonstrate that risky and ambiguous decision-making are associated with partially dissociable patterns of neural activation. Worry proneness was not associated with widespread alterations in behavioral performance or uncertainty-related neural responses; however, exploratory analyses identified localized associations between worry proneness and prefrontal neural responses during risky decision-making. These findings suggest that individual differences in worry proneness may be related to selective variation in specific neural processes rather than broad alterations in the neural systems supporting uncertainty processing. Full article
(This article belongs to the Special Issue Neuroscience of Cognition and Motor Control)
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