Lipid Peroxidation: Analysis and Applications in Biological Systems

Dear Colleagues,

It is globally known the interaction of free radical/reactive oxygen species (ROS) in lipid metabolism, namely polyunsaturated fatty acids are the core source of lipid peroxidation reaction in the biological systems. The metabolites released can be biomarkers of oxidative stress such as isoprostanes in mammals and phytoprostanes in plants and food or act as mediators in signalling pathways to redox responses, and even displayed some health benefits. Collectively, they are also known as oxylipins and are ubiquitous in the living system. In retrospect, antioxidants have been known for decades to regulate the release of these metabolites and prevent progression of diseases, and recently, phytochemicals tandem fatty acids including lipophenols showed potent antioxidant properties. However, proper selection of analysis for valid evaluation of antioxidant potential in desired applications is needed to understand the principle mechanisms of these oxylipins including synthesis, distribution, metabolism, and excretion in plants and mammals.

This Special Issue will publish original research papers and reviews on aspects of oxylipins derived from polyunsaturated fatty acids related to the following topics: health and diseases, metabolism, antioxidants, analytical views, chemistry and biomarkers.

• Oxylipins
• Isoprostanes
• Phytoprostanes
• Polyunsaturated fatty acids
• Lipophenols 
• Mass spectrometry

Dr. Jetty Chung-Yung Lee
Dr. Thierry Durand
Guest Editors

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