Design and Discovery of New Antibacterial Agents: Past, Evolution, and Perspectives

Dear Colleagues,

Millions of human lives are being saved annually throughout the world because of antibiotics, be they natural (i.e., produced by microorganisms in their own habitat) or of synthetic origin. However, concern about antibacterial resistance increased in the late 1990s, and since then, many governmental and agency reports have advised decreasing use of antibacterials, appropriate choice of antibacterials and regimens, prevention of cross-infection, and development of new antibacterials. The COVID-19 pandemic has exacerbated this phenomenon, leading to critical conditions in several cases. The dearth of new medicines effective against antibiotic-resistant bacteria represents a growing global public health concern. The discovery and development of new antibiotics is urgently needed. This Special Issue invites manuscript submissions (research articles or reviews) to enlighten the scientific community on recent studies regarding the synthesis and/or biological evaluation of new antibacterial agents. In vitro and in vivo studies are encouraged, as well as papers regarding clinical studies, molecular modeling studies, ADMET studies, nanotechnology-based innovation, biomaterials, nanomaterials, hybrid materials, core–shell materials, thin films, and self-assembling systems for the development of new antibiotics. We are particularly interested in receiving manuscript from the academic community as well as contributions from the industry.

Dr. Alessia Catalano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

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