Antimicrobial Resistance in One Health Perspective: New Insights in Human, Animal, and Environment Interlace

Dear Colleagues,

The emergence of and constant increase in the occurrence of multiple antibiotic-resistant bacteria has become a global public health threat due to the lack of pharmacological methods to treat infections in humans and animals. Being ubiquitous, microorganisms represent a pool of antimicrobial traits in all ecological niches. The main drivers of antimicrobial resistance include the indiscriminate use and abuse of antimicrobials in human, animal, and environmental sectors. Given the strong and interdependent human, animal, and environmental interactions in the context of antimicrobial resistance, a coordinated approach such as the One-Health strategy is highly suitable to characterize and address this warning and emerging phenomenon.
This Special Issue aims to collect original papers and reviews investigating the issue of antimicrobial resistance in the context of the One-Health perspective. In particular, the main topics that should be discussed in this Special Issue include: the impact of the companion animal population and human–animal relationships on the cross-transmission of antimicrobial resistance traits; the influence of aquaculture on the diffusion of antibiotic residues to the terrestrial ecosystem via the food chain and its dispersion through wastewater in the aquatic ecosystems; the rule of domestic animal husbandry on antimicrobial resistance spread.

The topic of this Special Issue is perfectly in line with the aims and scope of the journal Antibiotics. This Special Issue aims to encourage the publication of original experimental and theoretical results that demonstrate how interactions between the main drivers of the antimicrobial resistance influence this emerging phenomenon. Moreover, the innovative data published in this issue could be helpful to implement the potential containment strategies against antimicrobial resistance.

Dr. Rosalia Crupi
Prof. Domenico Britti
Prof. Dr. Giuseppe Crescenzo
Dr. Carmine Merola
Dr. Giulia Caioni
Dr. Alessio Soggiu
Guest Editors

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