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Most Cited

  • Review
  • Open Access
543 Citations
41,597 Views
38 Pages

Polymer-Based Hydrogels Applied in Drug Delivery: An Overview

  • Nguyen Hoc Thang,
  • Truong Bach Chien and
  • Dang Xuan Cuong

27 June 2023

Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied for drug delivery applications because of their ability to hold large amounts of water and biological fluids and control drug release based on their unique physic...

  • Review
  • Open Access
197 Citations
38,176 Views
28 Pages

Pectin Hydrogels: Gel-Forming Behaviors, Mechanisms, and Food Applications

  • Nurul Saadah Said,
  • Ibukunoluwa Fola Olawuyi and
  • Won Young Lee

9 September 2023

Pectin hydrogels have garnered significant attention in the food industry due to their remarkable versatility and promising properties. As a naturally occurring polysaccharide, pectin forms three-dimensional (3D) hydrophilic polymer networks, endowin...

  • Review
  • Open Access
137 Citations
19,088 Views
21 Pages

Essential Guide to Hydrogel Rheology in Extrusion 3D Printing: How to Measure It and Why It Matters?

  • Helena Herrada-Manchón,
  • Manuel Alejandro Fernández and
  • Enrique Aguilar

26 June 2023

Rheology plays a crucial role in the field of extrusion-based three-dimensional (3D) printing, particularly in the context of hydrogels. Hydrogels have gained popularity in 3D printing due to their potential applications in tissue engineering, regene...

  • Review
  • Open Access
125 Citations
14,558 Views
50 Pages

22 March 2024

Hydrogels, being hydrophilic polymer networks capable of absorbing and retaining aqueous fluids, hold significant promise in biomedical applications owing to their high water content, permeability, and structural similarity to the extracellular matri...

  • Review
  • Open Access
113 Citations
23,777 Views
24 Pages

Application of Collagen-Based Hydrogel in Skin Wound Healing

  • Yuan Zhang,
  • Yong Wang,
  • Ying Li,
  • Yunpeng Yang,
  • Mingyuan Jin,
  • Xiaoying Lin,
  • Zeming Zhuang,
  • Kai Guo,
  • Tao Zhang and
  • Weiqiang Tan

27 February 2023

The repair of skin injury has always been a concern in the medical field. As a kind of biopolymer material with a special network structure and function, collagen-based hydrogel has been widely used in the field of skin injury repair. In this paper,...

  • Review
  • Open Access
106 Citations
17,973 Views
33 Pages

Oleogels as a Fat Substitute in Food: A Current Review

  • Roberta Claro da Silva,
  • Md. Jannatul Ferdaus,
  • Aline Foguel and
  • Thais Lomonaco Teodoro da Silva

24 February 2023

Fats and oils in food give them flavor and texture while promoting satiety. Despite the recommendation to consume predominantly unsaturated lipid sources, its liquid behavior at room temperature makes many industrial applications impossible. Oleogel...

  • Review
  • Open Access
101 Citations
56,955 Views
30 Pages

Aloe vera-Based Hydrogels for Wound Healing: Properties and Therapeutic Effects

  • Mariana Chelu,
  • Adina Magdalena Musuc,
  • Monica Popa and
  • Jose Calderon Moreno

3 July 2023

Aloe vera-based hydrogels have emerged as promising platforms for the delivery of therapeutic agents in wound dressings due to their biocompatibility and unique wound-healing properties. The present study provides a comprehensive overview of recent a...

  • Review
  • Open Access
95 Citations
25,892 Views
38 Pages

Gel Polymer Electrolytes: Advancing Solid-State Batteries for High-Performance Applications

  • Kanakaraj Aruchamy,
  • Subramaniyan Ramasundaram,
  • Sivasubramani Divya,
  • Murugesan Chandran,
  • Kyusik Yun and
  • Tae Hwan Oh

21 July 2023

Gel polymer electrolytes (GPEs) hold tremendous potential for advancing high-energy-density and safe rechargeable solid-state batteries, making them a transformative technology for advancing electric vehicles. GPEs offer high ionic conductivity and m...

  • Review
  • Open Access
91 Citations
16,085 Views
46 Pages

8 March 2024

Hydrogels are polymeric materials that possess a set of characteristics meeting various requirements of an ideal wound dressing, making them promising for wound care. These features include, among others, the ability to absorb and retain large amount...

  • Review
  • Open Access
90 Citations
14,084 Views
23 Pages

22 October 2023

In recent years, significant advancements in the field of advanced materials and hydrogel engineering have enabled the design and fabrication of smart hydrogels and nanogels that exhibit sensitivity to specific signals or pathological conditions, lea...

  • Review
  • Open Access
90 Citations
19,824 Views
29 Pages

Rheology of Gels and Yielding Liquids

  • Alexander Ya. Malkin,
  • Svetlana R. Derkach and
  • Valery G. Kulichikhin

3 September 2023

In this review, today’s state of the art in the rheology of gels and transition through the yield stress of yielding liquids is discussed. Gels are understood as soft viscoelastic multicomponent solids that are in the incomplete phase separatio...

  • Review
  • Open Access
84 Citations
15,858 Views
36 Pages

2 January 2025

This review summarizes the fundamental concepts, recent advancements, and emerging trends in the field of stimuli-responsive hydrogels. While numerous reviews exist on this topic, the field continues to evolve dynamically, and certain research direct...

  • Review
  • Open Access
82 Citations
8,451 Views
24 Pages

21 July 2023

Hydrogel-based bone tissue engineering is a potential strategy for treating bone abnormalities and fractures. Hyaluronic acid (HA) is a natural polymer that is widely distributed in the human body and plays a significant role in numerous physiologica...

  • Review
  • Open Access
80 Citations
13,866 Views
28 Pages

Aerogels for Thermal Protection and Their Application in Aerospace

  • Runze Jin,
  • Zihan Zhou,
  • Jia Liu,
  • Baolu Shi,
  • Ning Zhou,
  • Xinqiao Wang,
  • Xinlei Jia,
  • Donghui Guo and
  • Baosheng Xu

26 July 2023

With the continuous development of the world’s aerospace industry, countries have put forward higher requirements for thermal protection materials for aerospace vehicles. As a nano porous material with ultra-low thermal conductivity, aerogel ha...

  • Review
  • Open Access
78 Citations
10,875 Views
31 Pages

27 March 2023

Chitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, a...

  • Review
  • Open Access
77 Citations
7,824 Views
21 Pages

4 December 2023

Starch-based hydrogels have gained significant attention in biomedical applications as a type of drug delivery system due to their biocompatibility, biodegradability, and ability to absorb and release drugs. Starch-based hydrogels can serve as effect...

  • Review
  • Open Access
76 Citations
8,805 Views
22 Pages

25 October 2023

AI and ML have emerged as transformative tools in various scientific domains, including hydrogel design. This work explores the integration of AI and ML techniques in the realm of hydrogel development, highlighting their significance in enhancing the...

  • Article
  • Open Access
76 Citations
3,331 Views
17 Pages

29 August 2023

Sustained release is highly desired for “efficacious, safe and convenient” drug delivery, particularly for those anticancer drug molecules with toxicity. In this study, a modified coaxial electrospraying process was developed to coat a hy...

  • Review
  • Open Access
71 Citations
7,301 Views
27 Pages

15 March 2023

Hydrogels have been developed for different biomedical applications such as in vitro culture platforms, drug delivery, bioprinting and tissue engineering. Enzymatic cross-linking has many advantages for its ability to form gels in situ while being in...

  • Review
  • Open Access
69 Citations
9,396 Views
29 Pages

22 May 2023

Alginates are polysaccharides that are produced naturally and can be isolated from brown sea algae and bacteria. Sodium alginate (SA) is utilized extensively in the field of biological soft tissue repair and regeneration owing to its low cost, high b...

  • Review
  • Open Access
65 Citations
17,178 Views
28 Pages

Hydrogels—A Promising Materials for 3D Printing Technology

  • Gobi Saravanan Kaliaraj,
  • Dilip Kumar Shanmugam,
  • Arish Dasan and
  • Kamalan Kirubaharan Amirtharaj Mosas

22 March 2023

Hydrogels are a promising material for a variety of applications after appropriate functional and structural design, which alters the physicochemical properties and cell signaling pathways of the hydrogels. Over the past few decades, considerable sci...

  • Review
  • Open Access
64 Citations
6,206 Views
37 Pages

28 July 2023

Concrete as a building material is susceptible to degradation by environmental threats such as thermal diffusion, acid and sulphate infiltration, and chloride penetration. Hence, the inclusion of nanomaterials in concrete has a positive effect in ter...

  • Review
  • Open Access
64 Citations
15,681 Views
26 Pages

Progress of Hydrogel Dressings with Wound Monitoring and Treatment Functions

  • Shanshan Jin,
  • Md All Amin Newton,
  • Hongju Cheng,
  • Qinchen Zhang,
  • Weihong Gao,
  • Yuansheng Zheng,
  • Zan Lu,
  • Zijian Dai and
  • Jie Zhu

28 August 2023

Hydrogels are widely used in wound dressings due to their moisturizing properties and biocompatibility. However, traditional hydrogel dressings cannot monitor wounds and provide accurate treatment. Recent advancements focus on hydrogel dressings with...

  • Review
  • Open Access
63 Citations
13,687 Views
20 Pages

Rheological Considerations of Pharmaceutical Formulations: Focus on Viscoelasticity

  • Lívia Budai,
  • Marianna Budai,
  • Zsófia Edit Fülöpné Pápay,
  • Zsófia Vilimi and
  • István Antal

7 June 2023

Controlling rheological properties offers the opportunity to gain insight into the physical characteristics, structure, stability and drug release rate of formulations. To better understand the physical properties of hydrogels, not only rotational bu...

  • Review
  • Open Access
63 Citations
16,061 Views
36 Pages

Chitosan Hydrogels for Water Purification Applications

  • Mariana Chelu,
  • Adina Magdalena Musuc,
  • Monica Popa and
  • Jose M. Calderon Moreno

17 August 2023

Chitosan-based hydrogels have gained significant attention for their potential applications in water treatment and purification due to their remarkable properties such as bioavailability, biocompatibility, biodegradability, environmental friendliness...

  • Review
  • Open Access
63 Citations
9,841 Views
32 Pages

17 December 2023

Rheological characterisation plays a crucial role in developing and optimising advanced materials in the form of hydrogels and aerogels, especially if 3D printing technologies are involved. Applications ranging from tissue engineering to environmenta...

  • Review
  • Open Access
62 Citations
14,146 Views
15 Pages

Progress in Research on Metal Ion Crosslinking Alginate-Based Gels

  • Yantao Wang,
  • Zhenpeng Shen,
  • Huili Wang,
  • Zhaoping Song,
  • Dehai Yu,
  • Guodong Li,
  • Xiaona Liu and
  • Wenxia Liu

27 December 2024

Alginate is an important natural biopolymer and metal ion-induced gelation is one of its most significant functional properties. Alginate-based hydrogels crosslinked with metal ions are commonly utilized in the food, biomedical, tissue engineering, a...

  • Review
  • Open Access
62 Citations
22,697 Views
23 Pages

25 October 2024

Hydrogels are known for their high water retention capacity and biocompatibility and have become essential materials in tissue engineering and drug delivery systems. This review explores recent advancements in hydrogel technology, focusing on innovat...

  • Review
  • Open Access
61 Citations
9,761 Views
38 Pages

1 May 2023

Chitosan hydrogels have a wide range of applications in tissue engineering scaffolds, mainly due to the advantages of their chemical and physical properties. This review focuses on the application of chitosan hydrogels in tissue engineering scaffolds...

  • Review
  • Open Access
59 Citations
11,174 Views
39 Pages

Application of Silk-Fibroin-Based Hydrogels in Tissue Engineering

  • Yihan Lyu,
  • Yusheng Liu,
  • Houzhe He and
  • Hongmei Wang

22 May 2023

Silk fibroin (SF) is an excellent protein-based biomaterial produced by the degumming and purification of silk from cocoons of the Bombyx mori through alkali or enzymatic treatments. SF exhibits excellent biological properties, such as mechanical pro...

  • Review
  • Open Access
59 Citations
16,076 Views
28 Pages

Food Emulsion Gels from Plant-Based Ingredients: Formulation, Processing, and Potential Applications

  • Canice Chun-Yin Yiu,
  • Sophie Wenfei Liang,
  • Kinza Mukhtar,
  • Woojeong Kim,
  • Yong Wang and
  • Cordelia Selomulya

26 April 2023

Recent advances in the understanding of formulations and processing techniques have allowed for greater freedom in plant-based emulsion gel design to better recreate conventional animal-based foods. The roles of plant-based proteins, polysaccharides,...

  • Review
  • Open Access
58 Citations
7,812 Views
19 Pages

16 May 2023

The enervating side effects of chemotherapeutic drugs have necessitated the use of targeted drug delivery in cancer therapy. To that end, thermoresponsive hydrogels have been employed to improve the accumulation and maintenance of drug release at the...

  • Review
  • Open Access
56 Citations
10,017 Views
25 Pages

Bigels as Delivery Systems: Potential Uses and Applicability in Food

  • Alyssa Francavilla,
  • Maria G. Corradini and
  • Iris J. Joye

11 August 2023

Bigels have been mainly applied in the pharmaceutical sector for the controlled release of drugs or therapeutics. However, these systems, with their intricate structures, hold great promise for wider application in food products. Besides their classi...

  • Review
  • Open Access
55 Citations
10,661 Views
35 Pages

3D-Printed Hydrogel for Diverse Applications: A Review

  • Arpana Agrawal and
  • Chaudhery Mustansar Hussain

7 December 2023

Hydrogels have emerged as a versatile and promising class of materials in the field of 3D printing, offering unique properties suitable for various applications. This review delves into the intersection of hydrogels and 3D printing, exploring current...

  • Review
  • Open Access
55 Citations
10,021 Views
26 Pages

Recent Advances of Chitosan-Based Hydrogels for Skin-Wound Dressings

  • Wei Guo,
  • Xiaoyue Ding,
  • Han Zhang,
  • Zhenzhong Liu,
  • Yanting Han,
  • Qianqian Wei,
  • Oseweuba Valentine Okoro,
  • Amin Shavandi and
  • Lei Nie

29 February 2024

The management of wound healing represents a significant clinical challenge due to the complicated processes involved. Chitosan has remarkable properties that effectively prevent certain microorganisms from entering the body and positively influence...

  • Review
  • Open Access
55 Citations
7,131 Views
28 Pages

Chitosan-Based Hydrogel in the Management of Dermal Infections: A Review

  • Popat Mohite,
  • Pudji Rahayu,
  • Shubham Munde,
  • Nitin Ade,
  • Vijay R. Chidrawar,
  • Sudarshan Singh,
  • Titilope J. Jayeoye,
  • Bhupendra G. Prajapati,
  • Sankha Bhattacharya and
  • Ravish J. Patel

24 July 2023

The main objective of this review is to provide a comprehensive overview of the current evidence regarding the use of chitosan-based hydrogels to manage skin infections. Chitosan, a naturally occurring polysaccharide derived from chitin, possesses in...

  • Review
  • Open Access
54 Citations
19,886 Views
36 Pages

Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings

  • Adina Alberts,
  • Dana-Ionela Tudorache,
  • Adelina-Gabriela Niculescu and
  • Alexandru Mihai Grumezescu

7 February 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic wound management by addressing challenges such as infection control, moisture balance, and enhanced healing. Important progress has been made, especially wi...

  • Review
  • Open Access
54 Citations
14,952 Views
36 Pages

Gel Formulations for Topical Treatment of Skin Cancer: A Review

  • Marta Slavkova,
  • Borislav Tzankov,
  • Teodora Popova and
  • Christina Voycheva

22 April 2023

Skin cancer, with all its variations, is the most common type of cancer worldwide. Chemotherapy by topical application is an attractive strategy because of the ease of application and non-invasiveness. At the same time, the delivery of antineoplastic...

  • Review
  • Open Access
54 Citations
13,101 Views
42 Pages

Food-Grade Oleogels: Trends in Analysis, Characterization, and Applicability

  • Simona Perța-Crișan,
  • Claudiu-Ștefan Ursachi,
  • Bianca-Denisa Chereji,
  • Iolanda Tolan and
  • Florentina-Daniela Munteanu

6 May 2023

Currently, a large number of scientific articles can be found in the research literature in the field focusing on the use of oleogels for food formulation to improve their nutritional properties. The present review focuses on the most representative...

  • Review
  • Open Access
54 Citations
10,923 Views
34 Pages

23 January 2025

There is ongoing research for biomedical applications of polyvinyl alcohol (PVA)-based hydrogels; however, the execution of this has not yet been achieved at an appropriate level for commercialization. Advanced perception is necessary for the design...

  • Review
  • Open Access
54 Citations
6,625 Views
32 Pages

2 June 2024

At the forefront of advanced material technology, radiation-induced hydrogels present a promising avenue for innovation across various sectors, utilizing gamma radiation, electron beam radiation, and UV radiation. Through the unique synthesis process...

  • Review
  • Open Access
52 Citations
6,705 Views
26 Pages

Recent Advances in Nanocellulose Aerogels for Efficient Heavy Metal and Dye Removal

  • Azfaralariff Ahmad,
  • Mohamad Anuar Kamaruddin,
  • Abdul Khalil H.P.S.,
  • Esam Bashir Yahya,
  • Syaifullah Muhammad,
  • Samsul Rizal,
  • Mardiana Idayu Ahmad,
  • Indra Surya and
  • C. K. Abdullah

16 May 2023

Water pollution is a significant environmental issue that has emerged because of industrial and economic growth. Human activities such as industrial, agricultural, and technological practices have increased the levels of pollutants in the environment...

  • Review
  • Open Access
52 Citations
7,858 Views
23 Pages

Recent Advances in Stimuli-Responsive Hydrogel-Based Wound Dressing

  • Luigia Serpico,
  • Stefania Dello Iacono,
  • Aniello Cammarano and
  • Luca De Stefano

30 May 2023

Polymeric materials have found increasing use in biomedical applications in the last decades. Among them, hydrogels represent the chosen class of materials to use in this field, in particular as wound dressings. They are generally non-toxic, biocompa...

  • Review
  • Open Access
52 Citations
10,835 Views
37 Pages

30 June 2023

Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment. Hydrog...

  • Review
  • Open Access
51 Citations
11,678 Views
18 Pages

NaDES Application in Cosmetic and Pharmaceutical Fields: An Overview

  • Carla Villa,
  • Debora Caviglia,
  • Francesco Saverio Robustelli della Cuna,
  • Guendalina Zuccari and
  • Eleonora Russo

28 January 2024

Natural deep eutectic solvents (NaDES) represent a new generation of green, non-flammable solvents, useful as an efficient alternative to the well-known ionic liquids. They can be easily prepared and exhibit unexpected solubilizing power for lipophil...

  • Review
  • Open Access
48 Citations
5,548 Views
27 Pages

Alginate Gel-Based Carriers for Encapsulation of Carotenoids: On Challenges and Applications

  • Milan Milivojević,
  • Aleksandra Popović,
  • Ivana Pajić-Lijaković,
  • Ivan Šoštarić,
  • Stefan Kolašinac and
  • Zora Dajić Stevanović

1 August 2023

Sodium alginate is one of the most interesting and the most investigated and applied biopolymers due to its advantageous properties. Among them, easy, simple, mild, rapid, non-toxic gelation by divalent cations is the most important. In addition, it...

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Gels - ISSN 2310-2861