Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Diabetic Foot Disease
edited by Xuefeng Yu
submission deadline 27 Feb 2026 | Viewed by 399 | Submission Open
Keywords: diabetes; diabetic foot; endocrinology; metabolic disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathology, Complications and Prognosis of Type 1 Diabetes
edited by Maurizio Delvecchio
submission deadline 27 Feb 2026 | Viewed by 217 | Submission Open
Keywords: type 1 diabetes mellitus; autoimmune β -cell destruction; diabetic complications; microvascular and macrovascular damage; diabetic ketoacidosis; glycemic control; disease prognosis; immunopathogenesis
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Research of Gut Microbiota in Health and Diseases—2nd Edition submission deadline 28 Feb 2026 | 8 articles | Viewed by 29421 | Submission Open
Keywords: microbiota; gut; dysbiosis; gut microbiome; pathological conditions; metabolic disorders; autoimmune disease; inflammatory disorders; degenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Natural Product for the Interventions of Chronic Diseases: From Source to Therapy
edited by
submission deadline 28 Feb 2026 | 7 articles | Viewed by 24903 | Submission Open
Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Cellular and Molecular Biology of Neurodegenerative Disorders
edited by
submission deadline 28 Feb 2026 | 6 articles | Viewed by 22457 | Submission Open
Keywords: neurodegeneration; omics; biomarkers; systems biology; disease-modifying therapies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Musculoskeletal Injuries: Clinical, Radiological, and Biochemical Evaluation in Orthopedics submission deadline 28 Feb 2026 | 7 articles | Viewed by 20288 | Submission Open
Keywords: orthopedic surgery; sports injuries; bone cancer; diabetic foot; clinical evaluation; radiological evaluation; biomarkers; prognostic markers
(This special issue belongs to the Section Molecular and Translational Medicine)
Glioblastoma: Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 28 Feb 2026 | 5 articles | Viewed by 19097 | Submission Open
Keywords: drug delivery methods (TTFields; nanoparticles); immunotherapy; oncolytic virotherapy; cell metabolism (glycolysis; OXPHOS; fatty acid oxidation); epigenetic; biomarkers; gene therapy (CRISPR/Cas9)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Feature Reviews in Cell Death
edited by and Madalina Nistor
submission deadline 28 Feb 2026 | 5 articles | Viewed by 16907 | Submission Open
Keywords: cell death pathways; apoptosis; necrosis; biomarkers; therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Cellular and Pathogenesis Mechanisms in Oral Cancer
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 16416 | Submission Open
Keywords: oral carcinogenesis; oral cancer model; OSCC; oral cytology; biomarkers; targeted therapies; precision medicine; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Mesenchymal Stem Cells submission deadline 28 Feb 2026 | 3 articles | Viewed by 15739 | Submission Open
Keywords: mesenchymal stem cells; tissue repair and regeneration; immunomodulatory functions
(This special issue belongs to the Section Cell Biology and Pathology)
Progress in Cardiovascular Pharmacology submission deadline 28 Feb 2026 | 3 articles | Viewed by 14984 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Neuroendocrine Neoplasia and Endocrine Tumors: Pathogenic Features, Prognostic Markers and New Therapeutic Approaches
edited by
submission deadline 28 Feb 2026 | 6 articles | Viewed by 13866 | Submission Open
Keywords: neuroendocrine tumors; endocrine tumors; somatostatin analogues; carcinoid syndrome; PRRT; mTOR inhibitor; lymph node; neuroendocrine marker; hormone; ki67
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Diabetes: Comorbidities, Therapeutics and Insights (3rd Edition)
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 12703 | Submission Open
Keywords: diabetes; complications; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Liquid Biopsy from Technological Innovation to Therapeutic Intervention
edited by and
submission deadline 28 Feb 2026 | 7 articles | Viewed by 10979 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Breast Diseases and Histopathology
edited by Michał Budzik
submission deadline 28 Feb 2026 | 6 articles | Viewed by 10845 | Submission Open
Keywords: breast cancer; breast diseases; histopathology; biomarkers; screening; diagnosis; early detection; tumor microenvironment; pathophysiology; molecular biology
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Biomarker Discovery for Cardiovascular Disease
edited by and
submission deadline 28 Feb 2026 | 7 articles | Viewed by 10197 | Submission Open
Keywords: cardiovascular disease; genomics; transcriptomics; proteomics; metabolomics; multiomics; gene sequencing; liquid chromatography/gas chromatography tandem mass spectrometry; diagnostic biomarkers; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Progress in Nanotechnology-Based Therapeutic Strategies
edited by Ambra Del Grosso and Mariacristina Gagliardi
submission deadline 28 Feb 2026 | 3 articles | Viewed by 8406 | Submission Open
Keywords: nanotechnology-based therapies; targeted drug delivery; nanoparticles; nanostructures; cancer treatment; cardiovascular diseases; neurodegenerative diseases; infectious diseases; lysosomal storage disorders; regenerative medicine; tissue engineering; gene therapy; biochemical diagnostics; omics approaches; biological barriers
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Animal Models for the Study of Human Diseases
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 7509 | Submission Open
Keywords: animal models; zebrafish; mice; rats
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Research in Ocular Pathology submission deadline 28 Feb 2026 | 3 articles | Viewed by 6810 | Submission Open
Keywords: molecular pathology; ocular diseases; biomarkers; diabetic retinopathy; glaucoma; age-related macular degeneration; thyroid eye disease; inflammatory pathways; oxidative stress; angiogenesis; neurodegeneration; gene therapy; cell therapy; precision medicine; ocular imaging
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Wound Healing and Skin Regeneration
edited by and Siqi Fu
submission deadline 28 Feb 2026 | 4 articles | Viewed by 6361 | Submission Open
Keywords: wound healing; skin regeneration; biomaterials; stem cell therapy; tissue engineering; bioactive dressings; 3D bioprinting; growth factors; chronic wounds; regenerative medicine
The Role of Ion Channels and Transporters in Human Health and Diseases (2nd Edition)
edited by Teresa Soda
submission deadline 28 Feb 2026 | 2 articles | Viewed by 5897 | Submission Open
Keywords: ion channels; transporters; ion pumps; voltage-gated channels; ionotropic receptors; TRP channels; store-operated channels; piezo channels; NALCN channels; inositol-1; 4; 5-receptors; ryanodine receptors; two-pore channels; synaptic transmission; channelopathies; neurodegenerative disorders; cardiovascular disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurodegenerative Diseases: From Mechanisms to Therapeutic Approaches, 2nd Edition submission deadline 28 Feb 2026 | 4 articles | Viewed by 5835 | Submission Open
Keywords: neurodegenerative diseases; neurons; mechanism
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Cardiovascular Remodeling: Molecular Mechanisms and Therapeutic Targets
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5484 | Submission Open
Keywords: cardiac remodeling; vascular remodeling; ageing; pathogenesis; molecular mechanisms; diagnostics; therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Growth Hormone Disorders and Their Related Diseases: From Pathophysiology to Therapeutic Approaches
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 5279 | Submission Open
Keywords: growth; growth hormone deficiency; GH; IGF-1; pediatric endocrinology
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Autophagy, Apoptosis and Cancer: 2025 Update
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 5089 | Submission Open
Keywords: autophagy; apoptosis; glioblastoma; hypoxia-inducible factors (HIFs); female fertility and ovarian cancer; nanoparticle-based drug delivery; bioactive natural products
(This special issue belongs to the Section Cancer Biology and Oncology)
Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target—3rd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 4723 | Submission Open
Keywords: endothelial function; arterial stiffness; vascular medicine; cardiovascular risk; nitric oxide; reactive oxygen species; interleukins; inflammation; biomarkers
(This special issue belongs to the Section Cell Biology and Pathology)
Advanced Research on Skeletal Muscle Metabolism
edited by Lorenzo Sanesi
submission deadline 28 Feb 2026 | 1 articles | Viewed by 4719 | Submission Open
Keywords: energy metabolism; mebabolic signaling pathways; homeostasis; myokines; aging; atrophy; muscle metabolism
(This special issue belongs to the Section Molecular and Translational Medicine)
Application of Artificial Intelligence in Biomedicines
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 4599 | Submission Open
Keywords: artificial intelligence; generative artificial intelligence; precision medicine; clinical decision support; drug discovery; personalized therapy; trustworthy AI
(This special issue belongs to the Section Molecular and Translational Medicine)
Biotechnology in the Treatment and Management of Hearing Loss submission deadline 28 Feb 2026 | 2 articles | Viewed by 4378 | Submission Open
Keywords: hearing loss; gene therapy; regenerative medicine; cochlear implants; nanotechnology stem cell therapy; CRISPR-Cas9; auditory prosthetics; artificial intelligence; auditory regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma—2nd Edition
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 3836 | Submission Open
Keywords: checkpoint inhibitors; combinatorial treatments; hepatocellular carcinoma (HCC); immunotherapy; liver cancer; therapy; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Mechanisms and Therapeutic Approaches for Hepatocellular Carcinoma
edited by Lanqi Gong, and Yu Zhang
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3731 | Submission Open
Keywords: hepatocellular carcinoma; HCC diagnosis and prognosis; HCC mechanisms; therapeutic resistance; immunotherapy; targeted therapy; personalized medicine; drug development; clinical trials; translational studies
(This special issue belongs to the Section Cancer Biology and Oncology)
Pathophysiology and Therapeutic Innovations in Skin and Appendage Disorders
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 3490 | Submission Open
Keywords: skin disorders; skin development; skin pathophysiology; tumorigenesis; psoriasis; atopic dermatitis; acne; innovative therapies; molecular dermatology; translational skin research
(This special issue belongs to the Section Cell Biology and Pathology)
Microcirculation, Thrombosis, and Inflammation in Peripheral Artery Disease and in the Brain submission deadline 28 Feb 2026 | 3 articles | Viewed by 3298 | Submission Open
Keywords: microcirculation; thrombosis; inflammation; peripheral artery disease; brain
(This special issue belongs to the Section Molecular and Translational Medicine)
Pluripotent Stem Cells: Current Understanding and Future Directions—2nd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 3061 | Submission Open
Keywords: induced pluripotent stem cells; iPSC generation; somatic reprogramming; iPSC-derived cells; cell therapy; exosome therapy; therapeutic application; drug screening
(This special issue belongs to the Section Cell Biology and Pathology)
Pathogenesis and Treatment of Mycobacterium Tuberculosis Infection
edited by Sajid Nadeem
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2425 | Submission Open
Keywords: mycobacterium tuberculosis; pathogenesis; host-directed therapy; inflammation; necrosis; innate and adaptive immunity
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advances in Precision Cancer Therapy
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2291 | Submission Open
Keywords: personalized cancer therapy; targeted therapy; immunotherapy; cancer genomics; cancer biomarker; liquid biopsy; CAR-T cell therapy; kinase inhibitor; combination therapy; molecular profiling
(This special issue belongs to the Section Cancer Biology and Oncology)
Congenital Heart Disease: Diagnosis, Treatment and Prognosis
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2088 | Submission Open
Keywords: adult congenital heart disease; eisenmenger's syndrome; endocarditis; thromboprophylaxis
(This special issue belongs to the Section Molecular and Translational Medicine)
Immune Cell Reprogramming: Molecular Mechanisms and Therapeutic Approaches
edited by , and Paolo Convertini
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2072 | Submission Open
Keywords: immune cell reprogramming; immunometabolism; macrophage activation; gene expression regulation; cell signaling; innate immunity; adaptive immunity; metabolic disorders; chronic inflammation; targeted therapies
(This special issue belongs to the Section Immunology and Immunotherapy)
Recent Advances in Adipokines (3nd Edition)
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1888 | Submission Open
Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Innovations in Nanomedicine for Disease Management
edited by Anna Valentino and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1575 | Submission Open
Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Gastric Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatment
edited by Sharona B. Ross
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1388 | Submission Open
Keywords: gastric cancer; tumor microenvironment; molecular mechanism; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Human Stem Cells in Disease Modelling and Treatment (2nd Edition)
edited by Sofia M. Calado and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1354 | Submission Open
Keywords: induced pluripotent stem cells (iPSCs); embryonic stem cells (ESCs); disease models; cell therapies; cell therapy medicinal products (CTMPs); regenerative medicine
(This special issue belongs to the Section Biomedical Engineering and Materials)
Pyroptosis and Cellular Stress: Emerging Mechanisms and Therapeutic Targets
edited by Gang Du
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1150 | Submission Open
Keywords: pyroptosis; cellular stress; ROS; programmed cell death; gasdermin; cytokines; inflammation; infection; cellular metabolism; immunometabolism
(This special issue belongs to the Section Cell Biology and Pathology)
Cannabinoids in Therapeutics: Mechanisms, Signaling Pathways and Personalized Treatment Strategies
edited by and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 961 | Submission Open
Keywords: cannabinoids; endocannabinoid system; cancer; pain; inflammation; personalized medicine; receptor signaling; therapeutic development; drug delivery; pharmacogenomics; systems pharmacology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Kidney Disease: From Pathophysiology to Treatment submission deadline 28 Feb 2026 | 1 articles | Viewed by 774 | Submission Open
Keywords: acute kidney injury; chronic kidney disease; precision medicine; molecular mechanisms; biomarkers; therapeutic response
Peptide Therapeutic Approaches for Cancer Treatment submission deadline 28 Feb 2026 | Viewed by 653 | Submission Open
Keywords: peptide therapeutics; cancer treatment; drug delivery systems; molecular imaging; bioinformatics; machine learning and artificial intelligence (AI); therapeutic targeting; peptide– drug conjugates; personalized medicine; immunotherapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Pathogenesis, Diagnosis and Treatment of Endocrine Cancers submission deadline 28 Feb 2026 | 1 articles | Viewed by 614 | Submission Open
Keywords: thyroid; parathyroid; adrenal; paraganglioma; genomes; transcriptomes; signalling pathways; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Environmental Pollutants in Cancer and Chemoresistance submission deadline 28 Feb 2026 | Viewed by 461 | Submission Open
Keywords: environmental pollutants; cancer cells; therapeutic agents
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances of Amyloid-β Dynamics in Health and Diseases
edited by
submission deadline 28 Feb 2026 | Viewed by 456 | Submission Open
Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in Primary and Relapsed Ovarian Cancer
edited by Cornelia Bachmann
submission deadline 28 Feb 2026 | Viewed by 430 | Submission Open
Keywords: ovarian cancer; relapse; BRCA; genetics; immunotherapy; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
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