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Journal of Dementia and Alzheimer's Disease, Volume 3, Issue 4

2026 December - 9 articles

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Articles (9)

  • Perspective
  • Open Access

Dementia progressively erodes autonomy, personal identity, and the ability to manage everyday life, placing growing demands on the people who provide care. Many AI-based assistive tools respond to this challenge by prioritizing what the algorithm can...

  • Article
  • Open Access
58 Views
16 Pages

Background/Objectives: Population-based risk stratification for dementia is increasingly important in rapidly ageing societies. Developing prediction models for incident dementia using longitudinal survey data remains challenging because new events a...

  • Systematic Review
  • Open Access
206 Views
15 Pages

Background: The clinical adoption of anti-amyloid monoclonal antibodies, including lecanemab and donanemab, has changed Alzheimer’s disease management from primarily symptomatic care toward biologically targeted intervention. This transition su...

  • Article
  • Open Access
124 Views
12 Pages

Health Inequalities Within Memory Services—The Need for Service Standards

  • Hari Subramaniam,
  • Shahbaz Abdullah,
  • Damodar Chari,
  • Elizabeta Mukaetova-Ladinska and ,
  • Sujoy Mukherjee and
  • Mohan Bhat
  • + 1 author+ 0 author

Background/Objectives: Healthcare systems worldwide face challenges regarding dementia diagnosis and offered care. The focus within services has been on diagnosis and waiting times monitored through key centralised performance metrics. However, inequ...

  • Review
  • Open Access
481 Views
14 Pages

Background: Goal setting is a core component of Occupational Therapy (OT), yet its application in people with dementia remains complex due to cognitive impairment and contextual factors. Evidence on how goal setting is implemented in this population...

  • Review
  • Open Access
326 Views
22 Pages

Estrogen and Alzheimer’s Disease: Neurobiology, Epigenetics, and AI-Driven Therapeutic Design

  • Tianhua Zhai,
  • Risa Garg,
  • Peiming Li,
  • Zixuan Wen and ,
  • Yijing Su and
  • Li Shen
  • + 1 author+ 0 author

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, and women are disproportionately affected. This review examines the evidence that estrogen signaling contributes to this disparity and asks what a molecularly targeted therap...

  • Review
  • Open Access
453 Views
22 Pages

Background: Alzheimer’s disease (AD) care is increasingly communication-intensive, requiring sustained caregiver education, symptom monitoring, behavioral management, and coordination across fragmented clinical settings. Large language models (...

  • Review
  • Open Access
569 Views
20 Pages

Sleep Loss and Alzheimer’s Disease: Mechanisms, Risk Factors, and Cognitive Consequences—A Narrative Review

  • Antoniya Hachmeriyan,
  • Gabriela Georgieva Panayotova,
  • Annriya Anand,
  • Nimisha Reji and
  • Lili Grudeva

Sleep loss is increasingly recognized as a potentially modifiable factor in cognitive aging and Alzheimer’s disease (AD). Evidence supports a bidirectional relationship in which sleep disruption may both reflect early AD-related neurodegenerati...

  • Review
  • Open Access
369 Views
15 Pages

Alzheimer’s and related dementias are not inevitable consequences of aging. This manuscript proposes that they arise when cumulative stress exceeds the repair capacity of three biological systems critical for maintaining brain health: proteosta...

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J. Dement. Alzheimer's Dis. - ISSN 3042-4518