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Psychoactives, Volume 5, Issue 3

2026 September - 8 articles

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Articles (8)

  • Article
  • Open Access
475 Views
26 Pages

Nyaope, a highly addictive high-grade heroin mixture combined with various adulterants, presented a severe socio-economic and public health crisis in South Africa. The administration of chronic exposure to nyaope induces systemic neurobehavioral alte...

(This article belongs to the Special Issue New Psychoactive Substances and Emerging Trends: Pharmacology, Neurotoxicity and Public Health Implications)
  • Systematic Review
  • Open Access
388 Views
35 Pages

The Role of Phytomedicine in Managing Comorbid Depression and Recreational Substance Use in Epilepsy: A Systematic Review

  • Matome M. Sekhotha,
  • Mxolisi J. Ndlovu,
  • Morongwa J. Mojapelo,
  • Lebogang S. Ledwaba and ,
  • Dineo M. Mariri,
  • Keitumetse S. Ndlovu,
  • Thandi M. Lamola and
  • Tinashe Mutize
  • + 3 authors+ 0 author

The development of depression frequently impacts epileptic patients due to unmanaged central nervous system changes. This may severely reduce their quality of life. These mental conditions can lead to the administration of illicit drugs for self-medi...

(This article belongs to the Special Issue New Psychoactive Substances and Emerging Trends: Pharmacology, Neurotoxicity and Public Health Implications)
  • Review
  • Open Access
1,770 Views
32 Pages

The global drug landscape is undergoing its most profound transformation since the emergence of the modern illicit drug market during the twentieth century. For decades, drug policies, analytical toxicology, forensic science, and public health respon...

  • Review
  • Open Access
1,374 Views
15 Pages

Background: Alcohol use disorder (AUD) remains a leading contributor to global morbidity, yet conventional treatments often yield suboptimal outcomes and high relapse rates. Psilocybin-assisted therapy has re-emerged as a potential intervention for s...

(This article belongs to the Special Issue New Psychoactive Substances and Emerging Trends: Pharmacology, Neurotoxicity and Public Health Implications)
  • Article
  • Open Access
695 Views
9 Pages

Serotonergic Antidepressant Use Is Not Associated with Increased Revision but Alters Postoperative Pain Following Rotator Cuff Repair

  • Ronak J. Mahatme,
  • Shawn A. Moore,
  • Anish Gangavaram,
  • Esha Reddy and ,
  • David L. Bernholt and
  • Brian M. Grawe
  • + 1 author+ 0 author

Rotator cuff tears are common, and although surgical repair is frequently performed, re-tear and complication rates remain substantial. The impact of selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibito...

  • Article
  • Open Access
548 Views
10 Pages

Association Between Psychological Moral Injury and Delay Discounting in Military Veterans: A Behavioral Economic Perspective

  • Justin T. McDaniel,
  • Ethan Mudd,
  • Jamale King,
  • Jolie N. Haun and ,
  • Christine Melillo,
  • Logan Jerolds,
  • Kelly Clary and
  • Katherine Selber
  • + 3 authors+ 0 author

Background/Objectives: In a recent meta-analysis of 1186 empirical studies, results showed that impulsivity may be one of the most important predictors of substance use. As such, the current study examined the association between an emerging psycholo...

  • Commentary
  • Open Access
763 Views
11 Pages

The nature of the psychedelic experience, and the distinctive phenomenological features it generates, leaves it susceptible to an unresolved epistemological tension between first-person phenomenological reports and claims about the fundamental nature...

  • Systematic Review
  • Open Access
1,350 Views
25 Pages

Cannabis use among adolescents and young adults has increased alongside legalization, commercialization, and higher product potency. However, evidence regarding the effectiveness of interventions to prevent or reduce cannabis use remains heterogeneou...

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Psychoactives - ISSN 2813-1851