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Oral, Volume 5, Issue 2

2025 June - 25 articles

Cover Story: Salivary biomarkers have been extensively studied in relation to oral diseases, including periodontal disease, oral cancer, and dental caries, in addition to systemic conditions such as diabetes, cardiovascular diseases, and neurological disorders. Advances in proteomics, genomics, and metabolomics have significantly enhanced the sensitivity and specificity of biomarker analysis. Techniques such as enzyme-linked immunosorbent assay (ELISA), polymerase chain reaction (PCR), mass spectrometry, and biosensor technologies enable the reliable detection of biomarkers, including inflammatory cytokines, oxidative stress markers, and microRNAs. However, standardization of sample collection, processing, and analysis remains a key challenge for clinical application. View this paper
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Articles (25)

  • Article
  • Open Access
1,897 Views
16 Pages

16 June 2025

Background: Class II Division 1 malocclusion is often characterized by an increased overjet, which has traditionally been considered a negative predictor of aesthetic outcomes, treatment efficacy, and long-term stability. Although early two-phase tre...

  • Case Report
  • Open Access
4,520 Views
13 Pages

10 June 2025

Background/Objectives: Orthodontic camouflage is a treatment strategy designed to address mild to moderate skeletal discrepancies through dental compensation when growth modification or orthognathic surgery (OGS) is unsuitable or declined by the pati...

  • Review
  • Open Access
3 Citations
2,876 Views
12 Pages

10 June 2025

Interim fixed dental prostheses (FDPs) play a crucial role in maintaining oral stability during the construction of final FDPs. Traditionally, interim FDPs were fabricated using conventional methods. However, advancements in digital dentistry have in...

  • Article
  • Open Access
2,838 Views
10 Pages

Safety and Feasibility of Dental Evaluation in Patients Undergoing Heart Valve Replacement Surgery: Retrospective Analysis

  • Lara Sviličić,
  • Kaja Topolnjak,
  • Petra Ivanišić,
  • Ivan Mikić,
  • Danica Vidović Juras,
  • Bernard Janković,
  • Valentina Rajić,
  • Marko Vuletić,
  • Marko Granić and
  • Vlaho Brailo
  • + 1 author

9 June 2025

Background/Objectives: Although there is a general consensus that patients should have dental evaluation before heart valve surgery, data on the extent and complications of this evaluation are scarce. The objective was to analyze safety and feasibili...

  • Article
  • Open Access
1 Citations
1,840 Views
13 Pages

Knowledge and Attitudes of Dentists and Dental Students in the Early Diagnosis of Oral Cancer: A Cross-Sectional Descriptive Observational Study

  • Maria Miguel Silva,
  • Lucrezia Maria Vozzo,
  • Tiago Marques,
  • Nélio Veiga,
  • Juliana Campos Hasse Fernandes,
  • Gustavo Vicentis Oliveira Fernandes and
  • Patrícia Couto

9 June 2025

Objective: This study aimed to evaluate and compare the knowledge and attitudes of dentists and dental students regarding the early diagnosis of oral cancer. Study Design: Data were collected using a questionnaire administered to students on an integ...

  • Article
  • Open Access
1 Citations
3,032 Views
13 Pages

Enhanced Proximal Caries Remineralization Using Cav-Aid®, a Novel Fluoride Delivery Device: An In Vitro Study

  • Chase David Hardy,
  • Bennett Tochukwu Amaechi,
  • Kannan Kanthaiah,
  • Amos Chinedu Obiefuna,
  • Mahalakshmi Vijayaraghavan,
  • Nahid Iftikhar,
  • Kyumin Whang,
  • Maria-Jose Cervantes Mendez and
  • Stanislaus Dyda

6 June 2025

Objective: This study evaluated the efficacy of a novel interproximal fluoride delivery device, Cav-Aid®, in remineralizing initial proximal caries, comparing it with conventional fluoride treatments. Methods: Initial caries lesions were produced...

  • Case Report
  • Open Access
1,311 Views
15 Pages

Comprehensive Management of Odontogenic Myxofibroma in the Mandible: A Four-Year Follow-Up Case Report with a Review of Differential Diagnosis and Treatment Approaches

  • Joanna Wójcik,
  • Liliia Yefanova,
  • Kacper Nijakowski,
  • Katarzyna Bednarek-Rajewska,
  • Krzysztof Osmola and
  • Maciej Okła

3 June 2025

Odontogenic myxofibroma (OMF) is a rare, benign, and slow-growing tumour arising from odontogenic ectomesenchyme. Despite its low prevalence, accounting for approximately 0.5% to 17.7% of all odontogenic tumours worldwide and 3.1% in specific regiona...

  • Case Report
  • Open Access
4,577 Views
11 Pages

Fusion, Gemination or a Morphological Variation? A Case Report on a Diagnostically Challenging Mandibular Molar

  • Argyro Kavadella,
  • Ioannis Papavasileiou,
  • Maria-Areti Salamouri,
  • Ioannis Papavasileiou and
  • Elpida-Niki Emmanouil-Nikoloussi

1 June 2025

Background/Objectives: Dental anomalies can manifest as a consequence of developmental defects and/or genetic influences, which disrupt the normal functioning of the oral cavity and present in various forms. Cases of fusion, gemination and concrescen...

  • Article
  • Open Access
1,855 Views
13 Pages

Effects of Tooth Loss and Denture Wear on Nutritional Status of a Sample of Elderly Patients Attending the Dental Teaching Hospital in Peradeniya, Sri Lanka

  • Pannilage Bimali Teshani Perera,
  • Weerakkody Sachini Nimthara Perera,
  • Udaveediya Lekam Ralalage Hansini Amanda Premathilaka,
  • Sachith Piyumal Abeysundara,
  • Kehinde Kazeem Kanmodi,
  • Ruwan Duminda Jayasinghe and
  • Rasika Manori Jayasinghe

23 May 2025

Background: The rapidly growing elderly population in Sri Lanka faces multiple challenges, including the ill effects of tooth loss. Tooth loss and denture wear could both affect the amount and variety of food intake of the elders, leading to a state...

  • Article
  • Open Access
3 Citations
3,425 Views
15 Pages

20 May 2025

Aim: This study aimed to determine the oral health profile of children with autism spectrum disorder and to analyze the impact of their oral health status on their personal quality of life and the quality of life of their families. Materials and Meth...

  • Review
  • Open Access
6,949 Views
24 Pages

Mycophenolate Mofetil in the Management of Oral Mucocutaneous Diseases: Current Evidence and Future Perspectives

  • Khalid Aljohani,
  • Ghada H. Naguib,
  • Abdulghani I. Mira,
  • Abeer Alnowaiser,
  • Mohamed T. Hamed,
  • Ahmed O. Abougazia,
  • Ghaida A. Alzarani,
  • Raghad M. Noorsaeed and
  • Rayyan A. Kayal

15 May 2025

Background/Objectives: Mycophenolate mofetil (MMF) has emerged as a valuable immunosuppressive agent used in the management of oral mucocutaneous diseases, particularly in autoimmune and inflammatory conditions, such as pemphigus vulgaris (PV), oral...

  • Review
  • Open Access
2,363 Views
13 Pages

Investigating Masticatory Cycle Parameters and Functional Wear Characteristics in Older Removable Complete Denture Wearers: A Targeted Literature Review

  • Savvas Kamalakidis,
  • Athanasios Stratos,
  • Dimitrios Tortopidis,
  • Norina Consuela Forna and
  • Vassiliki Anastassiadou

14 May 2025

Background: Mandibular movement is inherently complex, involving both lateral and vertical components. In older adults, this complexity is compounded by diminished neuromuscular coordination and reduced proprioceptive feedback, often impairing effect...

  • Article
  • Open Access
2,794 Views
12 Pages

The Impact of Upper Jaw Expansion Treatment on Vertical Craniofacial Characteristics and Upper Airway Dimensions

  • Sara Crnković,
  • Doris Šimac Pavičić,
  • Anđelo Svirčić,
  • Magda Trinajstić Zrinski and
  • Višnja Katić

7 May 2025

Aim: This study aimed to assess the impact of rapid palatal expansion (RPE) treatment on vertical craniodentofacial characteristics and upper airway dimensions in individuals with crossbites and skeletal discrepancies. Subjects and Methods: The study...

  • Article
  • Open Access
2 Citations
1,660 Views
17 Pages

Assessing the Genotoxic Impact of Ni-Cr Alloys in Dental Prosthodontics: A Preliminary Comparative Analysis with and Without Beryllium

  • Florentina Caministeanu,
  • Viorel Stefan Perieanu,
  • Andrei Sabin Popa,
  • Loredana Sabina Cornelia Manolescu,
  • Andreea Angela Stetiu,
  • Radu Catalin Costea,
  • Mihai Burlibasa,
  • Andrei Vorovenci,
  • Raluca Mariana Costea and
  • Liliana Burlibasa
  • + 4 authors

7 May 2025

Objective: This study aims to evaluate cell proliferation capacity and micronuclei incidence in the presence of nickel–chromium (Ni-Cr)-based dental alloys, with and without the addition of beryllium (Be). The use of these alloys in dental pros...

  • Article
  • Open Access
3,467 Views
13 Pages

Stress Distribution in a Mandibular Kennedy Class I with Bilateral Implant-Assisted Removable Partial Denture: A Finite Element Analysis

  • Dagny Ochoa-Escate,
  • Freddy Valdez-Jurado,
  • Romel Watanabe,
  • Martha Pineda-Mejía,
  • Edwin Antonio Córdova Huayanay,
  • Maria Soledad Ventocilla Huasupoma,
  • Marcos Herrera Cisneros,
  • Giovanna Lujan Larreátegui,
  • Angela Quispe-Salcedo and
  • Jesús Julio Ochoa Tataje
  • + 1 author

5 May 2025

Objectives: This study evaluated the dental and alveolar bone stress distribution of a mandibular Kennedy Class I restored with a bilateral implant-assisted removable partial denture (IARPD) compared with a conventional removable partial denture (CRP...

  • Article
  • Open Access
1,923 Views
9 Pages

Bone Mineral Density, Water Fluoride Intake, and Dental Fluorosis in Adults from Northwest Mexico

  • Rosa O. Méndez-Estrada,
  • Abigail Vega-Velasco,
  • Ana M. Calderón de la Barca and
  • Graciela Caire-Juvera

1 May 2025

Background: Dental fluorosis (DF) is an irreversible alteration of tooth enamel formation caused by excessive fluoride (F) consumption during tooth growth, leading to skeletal fluorosis development due to the high F content of tap water, which should...

  • Case Report
  • Open Access
2 Citations
2,073 Views
9 Pages

24 April 2025

Medication-related osteonecrosis of the jaw (MRONJ) is a multifactorial condition defined as an adverse drug reaction that results in progressive jawbone destruction and necrosis in individuals treated with certain medications, occurring without a hi...

  • Article
  • Open Access
3 Citations
3,964 Views
14 Pages

Predicting Artificial Intelligence Acceptance in Dental Treatments Among Patients in Saudi Arabia: A Perceived Risks and Benefits Perspective

  • Rayan Sharka,
  • Bayan Skatawi,
  • Ghaday Sayyam,
  • Maya Abutaleb,
  • Mawadah Alshareef,
  • Mohammed Alamar,
  • Lujain Abualkhair and
  • Yousef Ezzat

16 April 2025

Background/Objectives: Artificial Intelligence (AI) is transforming dentistry by offering advanced solutions to improve diagnostic accuracy, optimize treatment planning, and advance patient care. However, as AI becomes more prevalent in dental practi...

  • Article
  • Open Access
1 Citations
2,014 Views
15 Pages

The Effect of a Manni Telescopic Herbst Appliance with Four Miniscrews (STM4) on the Treatment of a Class II Division I Malocclusion: A 3D Finite Element Study

  • Andrea Boggio,
  • Abdolreza Jamilian,
  • Antonio Manni,
  • Giorgio Gastaldi,
  • Rosana Farjaminejad,
  • Mojtaba Hasani and
  • Mauro Cozzani

10 April 2025

Aim: Class II Division I malocclusion poses significant challenges in orthodontics. The combination of a Herbst appliance and miniscrew anchorage emerged as a practical solution to improve skeletal and dental outcomes. This study employed finite elem...

  • Review
  • Open Access
24 Citations
9,254 Views
19 Pages

Salivary Biomarkers Identification: Advances in Standard and Emerging Technologies

  • Vlad Constantin,
  • Ionut Luchian,
  • Ancuta Goriuc,
  • Dana Gabriela Budala,
  • Florinel Cosmin Bida,
  • Cristian Cojocaru,
  • Oana-Maria Butnaru and
  • Dragos Ioan Virvescu

9 April 2025

Introduction: Salivary biomarkers have been extensively studied in relation to oral disease, such as periodontal disease, oral cancer, and dental caries, as well as systemic conditions including diabetes, cardiovascular diseases, and neurological dis...

  • Conference Report
  • Open Access
1 Citations
8,374 Views
8 Pages

ONJ (MRONJ) Update 2024: Osteonecrosis of the Jaw Related to Bisphosphonates and Other Drugs—Prevention, Diagnosis, Pharmacovigilance, Treatment—A National Italian Symposium

  • Vittorio Fusco,
  • Martina Coppini,
  • Gaetano La Mantia,
  • Paolo G. Arduino,
  • Fortunato Buttacavoli,
  • Alessio Gambino,
  • Francesco M. Erovigni,
  • Alberto Bedogni and
  • Giuseppina Campisi

3 April 2025

On 24 February 2024, Italian physicians, dentists and oral care specialists, students, nurses, psychologists, dental hygienists, and other professionals met (live or online) to discuss controversial issues about medication-related osteonecrosis of th...

  • Review
  • Open Access
7 Citations
10,713 Views
26 Pages

2 April 2025

Three-dimensional (3D) printing is transforming dentistry by enabling precise and personalized treatments in prosthodontics, orthodontics, and endodontics. However, challenges such as high costs, material limitations, and post-processing requirements...

  • Review
  • Open Access
5 Citations
5,585 Views
24 Pages

Cultural Themes Related to Oral Health Practices, Beliefs, and Experiences in Nigeria: A Scoping Review

  • Taofeek Kolawole Aliyu,
  • Olusegun Stephen Titus,
  • Oluwabunmi Tope Bernard,
  • Omolola Titilayo Alade,
  • Adebola Oluyemisi Ehizele and
  • Moréniké Oluwátóyìn Foláyan

2 April 2025

The objective of this scoping review was to map out the cultural themes related to oral health practices, beliefs, and experiences in Nigeria; explore mythologies about oral health in Nigeria; identify the perceived cultural significance of oral heal...

  • Technical Note
  • Open Access
2,187 Views
10 Pages

Digital Denture Cast-Free Workflow Merging Concepts and Advantages of Mucostatics and Mucocompressive Philosophies

  • Lucio Lo Russo,
  • Laura Guida,
  • Mauro Lorusso,
  • Alfredo De Lillo,
  • Domenico Ciavarella and
  • Fariba Esperouz

1 April 2025

Background: Mucostatic impressions have been always indicated in thin, sharp, or flabby ridges, and have been addressed for their beneficial effect on long-term residual ridge stability. Nonetheless, a purely mucostatic impression was not possible un...

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Oral - ISSN 2673-6373