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Oral, Volume 5, Issue 4

December 2025 - 32 articles

Cover Story: Obstructive sleep apnea (OSA) often remains undiagnosed because standard diagnostic tools such as polysomnography are not easily accessible. Recent advances in artificial intelligence (AI) have enabled deep learning models to analyze craniofacial radiographs and identify anatomical patterns associated with OSA. This approach helps flag individuals who may be at elevated risk in dental and/or primary care settings. AI systems have demonstrated high accuracy in recognizing oropharyngeal crowding and anatomical imbalance of the upper airway, and interpretability analyses indicate that these models focus on clinically meaningful regions including the tongue, mandible, and upper airway. Integrating AI with routine imaging may therefore support early screening and guide timely referral for definitive diagnostic evaluation. View this paper
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Articles (32)

  • Article
  • Open Access
135 Views
19 Pages

Molar–Incisor Hypomineralisation: Possible Aetiological Factors and Their Association with Hypomineralised Second Primary Molars. A Pilot Study

  • Carolina Díaz-Hernández,
  • Gloria Saavedra-Marbán,
  • Nuria Esther Gallardo-López,
  • Manuel Joaquín de Nova-García,
  • Nere Zurro-Arrazola and
  • Antonia María Caleya

16 December 2025

Molar incisor hypomineralisation (MIH) is a developmental defect affecting permanent first molars and often the incisors too. Hypomineralised second primary molars (HSPM) have been proposed as potential early indicators of MIH. Aim: The aim was to id...

  • Case Report
  • Open Access
86 Views
12 Pages

Multiple Teeth Impaction in an Adult Patient Affected by Infantile Refsum Disease: A Case Report

  • Edoardo Staderini,
  • Gioele Gioco,
  • Federica Guglielmi,
  • Francesca Cazzato,
  • Licia Leccese,
  • Carmen Chiara Nacca and
  • Patrizia Gallenzi

16 December 2025

Introduction: Infantile Refsum disease (IRD) is considered one of the milder phenotypes within the Zellweger Spectrum Disorders (ZSDs), a group of peroxisomal biogenesis disorders characterized by a generalized impairment of peroxisomal function. Pat...

  • Review
  • Open Access
367 Views
18 Pages

Artificial Intelligence Tools for Dental Caries Detection: A Scoping Review

  • Patricio Meléndez Rojas,
  • Macarena Rodríguez Luengo,
  • Marcelo Durán Anrique,
  • Sven Niklander,
  • María F. Villalobos Dellafiori,
  • Jaime Jamett Rojas and
  • Alejandro Veloz Baeza

12 December 2025

Background/Objectives: Despite decades of technological progress, the diagnosis of dental caries still depends largely on subjective, operator-dependent assessment, leading to inconsistent detection of early lesions and delayed intervention. Artifici...

  • Review
  • Open Access
175 Views
25 Pages

Impact of Oral and Gut Microbiota Dysbiosis in Patients with Multiple Myeloma and Hematological Malignancies: A Narrative Review

  • Antonio Belmonte,
  • Ylenia Leanza,
  • Alessandro Polizzi,
  • Alessandra Romano,
  • Alessandro Allegra,
  • Rosalia Leonardi,
  • Cristina Panuzzo and
  • Gaetano Isola

11 December 2025

The interplay between the oral and gut microbiota and systemic health has garnered significant attention in recent years, particularly concerning hematological malignancies. Multiple myeloma and other hematological cancers are characterized by immune...

  • Article
  • Open Access
581 Views
19 Pages

Immediate Effects of Biomimetic Hydroxyapatite Toothpaste and Mouthwash on Dentin Hypersensitivity: A Randomized Controlled Trial

  • Andrea Scribante,
  • Matteo Pellegrini,
  • Alessandro Chiesa,
  • Stefania Crea and
  • Andrea Butera

10 December 2025

Background/Objectives: Dentin hypersensitivity (DH) is associated with gingival recession and dentin exposure. Biomimetic hydroxyapatite (HAp) reduces DH by occluding dentinal tubules, with conventional toothpaste formulations showing benefits. High-...

  • Article
  • Open Access
256 Views
12 Pages

Analysis of Maxillary Anterior Tooth Dimensions and Proportions in Young Cambodians: A Cross-Sectional Study

  • Aliza Tithphit,
  • Benedikt Schneider,
  • Ahmed Othman,
  • Veasna Phit,
  • Hong Yoeu Tith and
  • Constantin von See

3 December 2025

Background/Purpose: The study aimed to analyze the dimensions and width-to-length ratios of the maxillary anterior teeth in young native Cambodian adults and to assess their relationship with the golden proportion, symmetry, and sexual dimorphism. Ma...

  • Article
  • Open Access
263 Views
16 Pages

PRF Membranes Enhance Postoperative Recovery After Periapical Surgery: A Single-Blind Randomized Pilot Trial Using 3D Imaging

  • Martin Major,
  • Melinda Polyák,
  • Tamás Würsching,
  • Gábor Kammerhofer,
  • Éva Kocsis,
  • Zsolt Németh and
  • György Szabó

3 December 2025

Background: Periapical surgery is indicated for persistent periapical lesions that do not respond to conventional endodontic therapy, yet postoperative recovery is often hindered by pain, swelling, and delayed healing. Platelet-rich fibrin (PRF) memb...

  • Article
  • Open Access
204 Views
14 Pages

In Vivo Accuracy Assessment of Two Intraoral Scanners Using Open-Source Software: A Comparative Full-Arch Pilot Study

  • Francesco Puleio,
  • Fabio Salmeri,
  • Ettore Lupi,
  • Ines Urbano,
  • Roberta Gasparro,
  • Simone De Vita and
  • Roberto Lo Giudice

2 December 2025

Background: The precision of intraoral scanners (IOSs) is a key factor in ensuring the reliability of digital impressions, particularly in full-arch workflows. Although proprietary metrology tools are generally employed for scanner validation, open-s...

  • Article
  • Open Access
748 Views
35 Pages

The Antibacterial Effect of Eight Selected Essential Oils Against Streptococcus mutans: An In Vitro Pilot Study

  • Iulia Muntean,
  • Laura-Cristina Rusu,
  • Lavinia Cosmina Ardelean,
  • Codruta Victoria Tigmeanu,
  • Alexandra Roi,
  • Stefania Dinu and
  • Adina Andreea Mirea

1 December 2025

Background/Objectives: As antimicrobial dental treatments, based on chemical products, long tested for their efficacy, have been lately associated with developing antimicrobial resistance, there is a growing interest to identify and develop efficient...

  • Article
  • Open Access
220 Views
18 Pages

A Co-Design Approach to Developing a Hydrogel-Based Diagnostic Tool for Periodontal Disease: Perspectives from Healthcare Professionals

  • Adelaide Mensah,
  • Lyndsey McMullan,
  • Leonard Maguire,
  • Charles Benneh,
  • Ahmed Abuelhana,
  • Rosalina Intan Saputri and
  • Aaron J. Courtenay

27 November 2025

Background/Objectives: Early diagnosis of periodontal disease is vital for preventing disease progression and improving patient outcomes. This study explored healthcare professionals’ perspectives on a novel minimally invasive biofluid sampling...

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Oral - ISSN 2673-6373