2026 August - 19 articles
Parkinson’s disease (PD) is a neurodegenerative disorder caused by the loss of dopaminergic neurons. Its symptoms affect both motor functions—such as bradykinesia, rigidity, resting tremor, and postural instability—and non-motor fun...
Responsive neurostimulation (RNS) is a neuromodulation option for treatment of drug-resistant epilepsy (DRE). There is limited data reviewing bilateral thalamic and corticothalamic RNS therapy response. We performed a retrospective analysis of 21 pat...
Background: Neurocognitive testing in neuro-oncological patients often relies on time-intensive batteries with limited feasibility in this patient cohort. We evaluated the feasibility of the Bonn Leistungs Tracking Test (BLTT), a time-efficient scree...
Menopause represents a major neuroendocrine transition characterized by substantial hormonal, metabolic, vascular, and inflammatory changes that may increase vulnerability to cognitive decline and neurodegenerative disease. Declining estrogen levels...
Perfusion impairment is one of the major barriers to using machine perfusion to prepare brain tissue for research and clinical applications. As ischemia progresses, multiple mechanisms, including intravascular obstructions, perivascular cellular edem...
Malpighia mexicana has been traditionally used in Mexican ethnomedicine for the treatment of central nervous systems disorders. Previous studies have demonstrated neuropharmacological activity of crude extracts, but the contribution of enriched phyto...
Multiple sclerosis (MS) is the second-leading cause of disability in young adults [...]
Background: Multiple sclerosis (MS) is a chronic inflammatory, autoimmune, and neurodegenerative disease of the central nervous system. Our study aimed to examine the relationship between serum iron levels and the following clinical parameters: depre...
Background: Current treatments for myasthenia gravis (MG), while improving outcomes, are often associated with adverse effects, and a proportion of patients remain refractory to standard therapies. Eculizumab, a humanized monoclonal antibody targetin...
Background: Cell and mouse models studies demonstrate NLRP3 inflammasome involvement in amyotrophic lateral sclerosis (ALS) neuroinflammation. Peripheral blood mononuclear cells (PBMCs) are a promising, yet understudied, source of in vivo inflammasom...
Background: Atrial fibrillation (AF) is a common but frequently undiagnosed cause of ischemic stroke, particularly among patients with cryptogenic stroke and embolic stroke of undetermined source (ESUS). Implantable cardiac monitors (ICMs) enable pro...
Mitofusin-2 (MFN2) variants are a well-established cause of Charcot–Marie–Tooth disease type 2A, although central nervous system involvement has increasingly been recognized in a subset of affected patients. We report a 51-year-old woman...
Rodent models, especially chronic stress paradigms, are essential in depression research, yet existing behavioral assessments often struggle to capture pathophysiological heterogeneity. We developed the Multimodal Behavior Scoring (MBS) algorithm, wh...
(1) Background: The effects of posterior parietal cortex (PPC)-targeted transcranial direct current stimulation (tDCS) on postural stability and cortical activity remain unclear. Therefore, this study aimed to investigate and compare changes in corti...
Brain injury after hypoxia–ischemia (HI) is the leading cause of morbidity and mortality in term and near-term neonates worldwide. The ferret is a promising translational model to study HI due to its gyrified brain and white-to-gray matter rati...
Traumatic intracranial aneurysms (TICAs) are rare lesions accounting for <1% of intracranial aneurysms and are associated with high morbidity and mortality. They frequently arise after blunt trauma and may develop days to months following the init...
Background: Monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway represent an effective preventive treatment for chronic migraine, including in patients with multiple prior therapeutic failures. However, a substantial pr...
This study investigated whether neuro-exergaming with an interactive physical and cognitive exercise system (iPACES), might alleviate symptoms in college students with symptoms of Attention Deficit Hyperactivity Disorder (sxADHD). It was hypothesized...
Noise exposure has become an increasingly prevalent public health concern, with effects extending beyond the auditory system. Accumulating evidence indicates that chronic noise exposure induces both structural and functional alterations in the centra...
