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Tomography, Volume 9, Issue 6

2023 December - 21 articles

Cover Story: Quantitative imaging biomarkers (QIBs) from diffusion-weighted (DW) and dynamic contrast-enhanced (DCE) MR imaging hold promise in characterizing tumor physiology. Limitations remain with the accessibility of quantitative DWI multi-b-value and DCE pharmacokinetic analysis tools for radiologists and researchers. We present Quantitative Analysis and Multiparametric Evaluation Routines for MRI (MRI-QAMPER) software for the extraction of QIBs from MRI data. MRI-QAMPER is MATLAB based (The Mathworks) with advanced routines for post-processing quantitative DWI, DCE, T1, and T2 data. MRI-QAMPER analyzes data from brain, pancreas, bladder, and other organs via customizable presets for non-linear fitting. MRI-QAMPER is approved with National Cancer Institute Quantitative Imaging Network Level 5 “Clinical Benchmark” status for use in clinical trials. View this paper
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Articles (21)

  • Case Report
  • Open Access
2 Citations
2,655 Views
9 Pages

Exploring CNS Involvement in Pain Insensitivity in Hereditary Sensory and Autonomic Neuropathy Type 4: Insights from Tc−99m ECD SPECT Imaging

  • Cheng-Chun Chiang,
  • Yu-Che Wu,
  • Chiao-Hsin Lan,
  • Kuan-Chieh Wang,
  • Hsuan-Ching Tang and
  • Shin-Tsu Chang

18 December 2023

Hereditary sensory and autonomic neuropathy type 4 (HSAN4), also known as congenital insensitivity to pain with anhidrosis (CIPA), is a rare genetic disorder caused by NTRK1 gene mutations, affecting nerve growth factor signaling. This study investig...

  • Article
  • Open Access
3 Citations
4,950 Views
14 Pages

Non-A Non-B Acute Aortic Dissection: Is There Some Confusion in the Radiologist’s Mind?

  • Tullio Valente,
  • Giacomo Sica,
  • Federica Romano,
  • Gaetano Rea,
  • Roberta Lieto,
  • Marisa De Feo,
  • Alessandro Della Corte,
  • Salvatore Guarino,
  • Candida Massimo and
  • Giorgio Bocchini
  • + 2 authors

15 December 2023

Background: The aim of this study is to define and determine the rate of acute non-A–non-B aortic dissections, and to evaluate CT angiography findings and possible complications, as well as to discuss management strategies and currently availab...

  • Article
  • Open Access
2,144 Views
14 Pages

MSTAC: A Multi-Stage Automated Classification of COVID-19 Chest X-ray Images Using Stacked CNN Models

  • Thanakorn Phumkuea,
  • Thakerng Wongsirichot,
  • Kasikrit Damkliang,
  • Asma Navasakulpong and
  • Jarutas Andritsch

13 December 2023

This study introduces a Multi-Stage Automated Classification (MSTAC) system for COVID-19 chest X-ray (CXR) images, utilizing stacked Convolutional Neural Network (CNN) models. Suspected COVID-19 patients often undergo CXR imaging, making it valuable...

  • Article
  • Open Access
1 Citations
2,604 Views
11 Pages

Transnasal Endoscopic Pituitary Surgery—The Role of a CT Scan in Individual Tailoring of Posterior Septum Size Resection

  • Jakub Lubojacký,
  • Lenka Čábalová,
  • Michaela Mladoňová,
  • Viktória Hránková,
  • Tomáš Krejčí,
  • Jakub Mičaník,
  • Maria Miklošová,
  • Lačezar Ličev,
  • Pavel Komínek and
  • Petr Matoušek

12 December 2023

Objective: This study was designed to evaluate the possibility of predicting the minimum size of septal resection for safe tumor extraction in transnasal paraseptal pituitary adenoma resection from preoperative computed tomography scans. Methods: A r...

  • Article
  • Open Access
2,890 Views
11 Pages

Chest X-ray at Emergency Admission and Potential Association with Barotrauma in Mechanically Ventilated Patients: Experience from the Italian Core of the First Pandemic Peak

  • Pietro Andrea Bonaffini,
  • Francesco Stanco,
  • Ludovico Dulcetta,
  • Giancarla Poli,
  • Paolo Brambilla,
  • Paolo Marra,
  • Clarissa Valle,
  • Ferdinando Luca Lorini,
  • Mirko Mazzoleni and
  • Sandro Sironi
  • + 2 authors

8 December 2023

Barotrauma occurs in a significant number of patients with COVID-19 interstitial pneumonia undergoing mechanical ventilation. The aim of the current study was to investigate whether the Brixia score (BS) calculated on chest-X-rays acquired at the Eme...

  • Review
  • Open Access
7 Citations
10,516 Views
21 Pages

Imaging of Pathologies of the Temporal Bone and Middle Ear: Inflammatory Diseases, Their Mimics and Potential Complications—Pictorial Review

  • Christopher Kloth,
  • Annika Beck,
  • Nico Sollmann,
  • Meinrad Beer,
  • Marius Horger and
  • Wolfgang Maximilian Thaiss

8 December 2023

Imaging of the temporal bone and middle ear is challenging for radiologists due to the abundance of distinct anatomical structures and the plethora of possible pathologies. The basis for a precise diagnosis is knowledge of the underlying anatomy as w...

  • Review
  • Open Access
18 Citations
8,537 Views
32 Pages

A Systematic Literature Review of 3D Deep Learning Techniques in Computed Tomography Reconstruction

  • Hameedur Rahman,
  • Abdur Rehman Khan,
  • Touseef Sadiq,
  • Ashfaq Hussain Farooqi,
  • Inam Ullah Khan and
  • Wei Hong Lim

5 December 2023

Computed tomography (CT) is used in a wide range of medical imaging diagnoses. However, the reconstruction of CT images from raw projection data is inherently complex and is subject to artifacts and noise, which compromises image quality and accuracy...

  • Article
  • Open Access
4 Citations
3,415 Views
10 Pages

Automated High-Order Shimming for Neuroimaging Studies

  • Jia Xu,
  • Baolian Yang,
  • Douglas Kelley and
  • Vincent A. Magnotta

1 December 2023

B0 inhomogeneity presents a significant challenge in MRI and MR spectroscopy, particularly at high-field strengths, leading to image distortion, signal loss, and spectral broadening. Existing high-order shimming methods can alleviate these issues but...

  • Article
  • Open Access
5 Citations
4,178 Views
14 Pages

The Role of Cone-Beam Computed Tomography CT Extremity Arthrography in the Preoperative Assessment of Osteoarthritis

  • Marion Hamard,
  • Marta Sans Merce,
  • Karel Gorican,
  • Pierre-Alexandre Poletti,
  • Angeliki Neroladaki and
  • Sana Boudabbous

29 November 2023

Osteoarthritis (OA) is a prevalent disease and the leading cause of pain, disability, and quality of life deterioration. Our study sought to evaluate the image quality and dose of cone-beam computed tomography arthrography (CBCT-A) and compare them t...

  • Review
  • Open Access
3 Citations
6,390 Views
18 Pages

High-Resolution Phase-Contrast Tomography on Human Collagenous Tissues: A Comprehensive Review

  • Michele Furlani,
  • Nicole Riberti,
  • Maria Laura Gatto and
  • Alessandra Giuliani

27 November 2023

Phase-contrast X-ray imaging is becoming increasingly considered since its first applications, which occurred almost 30 years ago. Particular emphasis was placed on studies that use this technique to investigate soft tissues, which cannot otherwise b...

  • Article
  • Open Access
11 Citations
5,179 Views
13 Pages

Artificial Intelligence for Image-Based Breast Cancer Risk Prediction Using Attention

  • Stepan Romanov,
  • Sacha Howell,
  • Elaine Harkness,
  • Megan Bydder,
  • D. Gareth Evans,
  • Steven Squires,
  • Martin Fergie and
  • Sue Astley

24 November 2023

Accurate prediction of individual breast cancer risk paves the way for personalised prevention and early detection. The incorporation of genetic information and breast density has been shown to improve predictions for existing models, but detailed im...

  • Article
  • Open Access
2 Citations
3,219 Views
14 Pages

15 November 2023

Background: Measuring left ventricular ejection fraction (LVEF) is important for detecting heart failure, e.g., in treatment with potentially cardiotoxic chemotherapy. MRI is considered the reference standard for LVEF, but availability may be limited...

  • Article
  • Open Access
6 Citations
1,892 Views
10 Pages

Have Chest Imaging Habits Changed in the Emergency Department after the Pandemic?

  • Cüneyt Arıkan,
  • Ejder Saylav Bora,
  • Efe Kanter and
  • Fatma Nur Karaarslan

7 November 2023

The rate of patients undergoing tomography in the emergency department has increased in the last two decades. In the last few years, there has been a more significant increase due to the effects of the pandemic. This study aimed to determine the rate...

  • Article
  • Open Access
1 Citations
3,047 Views
12 Pages

6 November 2023

Introduction: Our institution is part of a provincial program providing annual breast MRI screenings to high-risk women. We assessed how MRI experience, background parenchymal enhancement (BPE), and the amount of fibroglandular tissue (FGT) affect th...

  • Article
  • Open Access
8 Citations
5,990 Views
15 Pages

A Quantitative Multiparametric MRI Analysis Platform for Estimation of Robust Imaging Biomarkers in Clinical Oncology

  • Eve LoCastro,
  • Ramesh Paudyal,
  • Amaresha Shridhar Konar,
  • Peter S. LaViolette,
  • Oguz Akin,
  • Vaios Hatzoglou,
  • Alvin C. Goh,
  • Bernard H. Bochner,
  • Jonathan Rosenberg and
  • Amita Shukla-Dave
  • + 3 authors

3 November 2023

There is a need to develop user-friendly imaging tools estimating robust quantitative biomarkers (QIBs) from multiparametric (mp)MRI for clinical applications in oncology. Quantitative metrics derived from (mp)MRI can monitor and predict early respon...

  • Article
  • Open Access
4 Citations
5,262 Views
13 Pages

2 November 2023

Dedicated cone-beam breast computed tomography (CBBCT) is an emerging modality and provides fully three-dimensional (3D) images of the uncompressed breast at an isotropic voxel resolution. In an effort to translate this modality to breast cancer scre...

  • Article
  • Open Access
6 Citations
3,061 Views
10 Pages

Reporting Diagnostic Reference Levels for Paediatric Patients Undergoing Brain Computed Tomography

  • Ali Alhailiy,
  • Essam Alkhybari,
  • Sultan Alghamdi,
  • Nada Fisal,
  • Sultan Aldosari and
  • Salman Albeshan

1 November 2023

Brain computed tomography (CT) is a diagnostic imaging tool routinely used to assess all paediatric neurologic disorders and other head injuries. Despite the continuous development of paediatric CT imaging, radiation exposure remains a concern. Using...

  • Review
  • Open Access
2 Citations
5,057 Views
13 Pages

Assessment of Computed Tomography Perfusion Research Landscape: A Topic Modeling Study

  • Burak B. Ozkara,
  • Mert Karabacak,
  • Konstantinos Margetis,
  • Vivek S. Yedavalli,
  • Max Wintermark and
  • Sotirios Bisdas

1 November 2023

The number of scholarly articles continues to rise. The continuous increase in scientific output poses a challenge for researchers, who must devote considerable time to collecting and analyzing these results. The topic modeling approach emerges as a...

  • Article
  • Open Access
12 Citations
3,333 Views
10 Pages

Idiopathic Normal Pressure Hydrocephalus: The Real Social and Economic Burden of a Possibly Enormous Underdiagnosis Problem

  • Gianpaolo Petrella,
  • Silvia Ciarlo,
  • Stefania Elia,
  • Rita Dal Piaz,
  • Paolo Nucera,
  • Angelo Pompucci,
  • Mauro Palmieri and
  • Alessandro Pesce

30 October 2023

Normal Pressure Hydrocephalus (iNPH) typically affects the elderly and can cause cognitive decline, resulting in its differential diagnosis with other neurodegenerative conditions. Moreover, it is probably underdiagnosed; such under- and misdiagnosis...

  • Case Report
  • Open Access
2 Citations
8,044 Views
7 Pages

27 October 2023

Introduction: Conus medullaris syndrome (CMS) is a distinctive spinal cord injury (SCI), which presents with varying degrees of upper motor neuron signs (UMNS) and lower motor neuron signs (LMNS). Herein, we present a case with a burst fracture injur...

  • Article
  • Open Access
1 Citations
4,224 Views
12 Pages

The Tomosynthesis Broken Halo Sign: Diagnostic Utility for the Classification of Newly Diagnosed Breast Tumors

  • Johannes Deeg,
  • Michael Swoboda,
  • Daniel Egle,
  • Verena Wieser,
  • Afschin Soleiman,
  • Valentin Ladenhauf,
  • Malik Galijasevic,
  • Birgit Amort,
  • Silke Haushammer and
  • Leonhard Gruber
  • + 1 author

24 October 2023

Background: Compared to conventional 2D mammography, digital breast tomosynthesis (DBT) offers greater breast lesion detection rates. Ring-like hypodense artifacts surrounding dense lesions are a common byproduct of DBT. This study’s purpose wa...

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Tomography - ISSN 2379-139X