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Biomimetics, Volume 10, Issue 6 (June 2025) – 68 articles

Cover Story (view full-size image): Birds use perching as a means to land and take off from different surfaces. This study presents a bioinspired perching mechanism to improve landing and takeoff behavior for a flapping-wing micro aerial vehicle. Mimicking the human hand, the lightweight gripper uses compliant claws actuated by shape memory alloy (SMA) springs that simulate muscle movement. The SMA-based system enables fast, bidirectional actuation using short electrical pulses. Optimized for cylindrical grasping, the 50 g gripper integrates SMA springs within its phalanges to reduce size and mass. Tests show a 16 N grasping force, enabling perching, grasping, and carrying tasks. The compact, adaptable design offers a simpler, more efficient alternative to traditional actuators for small-scale MAVs. View this paper
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58 pages, 8213 KiB  
Article
A Novel Exploration Stage Approach to Improve Crayfish Optimization Algorithm: Solution to Real-World Engineering Design Problems
by Harun Gezici
Biomimetics 2025, 10(6), 411; https://doi.org/10.3390/biomimetics10060411 - 19 Jun 2025
Viewed by 272
Abstract
The Crayfish Optimization Algorithm (COA) has limitations that affect its optimization performance seriously. The competition stage of the COA uses a simplified mathematical model that concentrates on relations of distance between crayfish only. It is deprived of a stochastic variable and is not [...] Read more.
The Crayfish Optimization Algorithm (COA) has limitations that affect its optimization performance seriously. The competition stage of the COA uses a simplified mathematical model that concentrates on relations of distance between crayfish only. It is deprived of a stochastic variable and is not able to generate an applicable balance between exploration and exploitation. Such a case causes the COA to have early convergence, to perform poorly in high-dimensional problems, and to be trapped by local minima. Moreover, the low activation probability of the summer resort stage decreases the exploration ability more and slows down the speed of convergence. In order to compensate these shortcomings, this study proposes an Improved Crayfish Optimization Algorithm (ICOA) that designs the competition stage with three modifications: (1) adaptive step length mechanism inversely proportional to the number of iterations, which enables exploration in early iterations and exploitation in later stages, (2) vector mapping that increases stochastic behavior and improves efficiency in high-dimensional spaces, (3) removing the Xshade parameter in order to abstain from early convergence. The proposed ICOA is compared to 12 recent meta-heuristic algorithms by using the CEC-2014 benchmark set (30 functions, 10 and 30 dimensions), five engineering design problems, and a real-world ROAS optimization case. Wilcoxon Signed-Rank Test, t-test, and Friedman rank indicate the high performance of the ICOA as it solves 24 of the 30 benchmark functions successfully. In engineering applications, the ICOA achieved an optimal weight (1.339965 kg) in cantilever beam design, a maximum load capacity (85,547.81 N) in rolling element bearing design, and the highest performance (144.601) in ROAS optimization. The superior performance of the ICOA compared to the COA is proven by the following quantitative data: 0.0007% weight reduction in cantilevers design (from 1.339974 kg to 1.339965 kg), 0.09% load capacity increase in bearing design (COA: 84,196.96 N, ICOA: 85,498.38 N average), 0.27% performance improvement in ROAS problem (COA: 144.072, ICOA: 144.601), and most importantly, there seems to be an overall performance improvement as the COA has a 4.13 average rank while the ICOA has 1.70 on CEC-2014 benchmark tests. Results indicate that the improved COA enhances exploration and successfully solves challenging problems, demonstrating its effectiveness in various optimization scenarios. Full article
(This article belongs to the Section Biological Optimisation and Management)
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11 pages, 5143 KiB  
Communication
Bio-Inspired 3D Affordance Understanding from Single Image with Neural Radiance Field for Enhanced Embodied Intelligence
by Zirui Guo, Xieyuanli Chen, Zhiqiang Zheng, Huimin Lu and Ruibin Guo
Biomimetics 2025, 10(6), 410; https://doi.org/10.3390/biomimetics10060410 - 19 Jun 2025
Viewed by 345
Abstract
Affordance understanding means identifying possible operable parts of objects, which is crucial in achieving accurate robotic manipulation. Although homogeneous objects for grasping have various shapes, they always share a similar affordance distribution. Based on this fact, we propose AFF-NeRF to address the problem [...] Read more.
Affordance understanding means identifying possible operable parts of objects, which is crucial in achieving accurate robotic manipulation. Although homogeneous objects for grasping have various shapes, they always share a similar affordance distribution. Based on this fact, we propose AFF-NeRF to address the problem of affordance generation for homogeneous objects inspired by human cognitive processes. Our method employs deep residual networks to extract the shape and appearance features of various objects, enabling it to adapt to various homogeneous objects. These features are then integrated into our extended neural radiance fields, named AFF-NeRF, to generate 3D affordance models for unseen objects using a single image. Our experimental results demonstrate that our approach outperforms baseline methods in the affordance generation of unseen views on novel objects without additional training. Additionally, more stable grasps can be obtained by employing 3D affordance models generated by our method in the grasp generation algorithm. Full article
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12 pages, 8480 KiB  
Article
Chemical and Biological Properties of C-Point Obturation Cones
by Marina Angélica Marciano, Paulo Jorge Palma, Ana Cristina Padilha Janini, Brenda Fornazaro Moraes, Thiago Bessa Marconato Antunes, Ribamar Lazanha Lucateli, Bruno Martini Guimarães, Mariza Akemi Matsumoto, Diana Bela Sequeira, Talita Tartari, Brenda Paula Figueiredo Almeida Gomes and Marco Antonio Hungaro Duarte
Biomimetics 2025, 10(6), 409; https://doi.org/10.3390/biomimetics10060409 - 18 Jun 2025
Viewed by 278
Abstract
This study evaluated the chemical composition and subcutaneous tissue biocompatibility of C-Point, a root canal filling material, compared to ProTaper gutta-percha cones (control). Material characterization was conducted using scanning electron microscopy with energy-dispersive spectroscopy (SEM-EDS). For biocompatibility assessment, both materials were implanted subcutaneously [...] Read more.
This study evaluated the chemical composition and subcutaneous tissue biocompatibility of C-Point, a root canal filling material, compared to ProTaper gutta-percha cones (control). Material characterization was conducted using scanning electron microscopy with energy-dispersive spectroscopy (SEM-EDS). For biocompatibility assessment, both materials were implanted subcutaneously in the dorsal connective tissue of sixteen albino rats (n = 8 per group). Histological evaluation of inflammatory infiltrate intensity was performed at 30 and 60 days post-implantation, with statistical analysis (significance set at p < 0.05). SEM-EDS analysis revealed distinct elemental compositions: C-Point primarily contained zirconium and cobalt ions, while gutta-percha cones demonstrated a strong zinc signature with trace amounts of barium, aluminum, and sulfur. Both materials exhibited similar particulate morphology with radiopaque inclusions. Histologically, no significant difference in inflammatory response was observed between C-Point and gutta-percha at any time point (p > 0.05). All specimens developed a fibrous encapsulation. The inflammatory profile showed temporal dynamics, with lymphocyte predominance during early stages that progressively diminished by the study endpoint. These findings demonstrate that while C-Point possesses a unique elemental profile dominated by zirconium, its tissue biocompatibility parallels that of conventional gutta-percha obturation materials. However, due to the absence of mechanical testing and the limited in vivo follow-up period, the long-term stability of the material remains uncertain. Full article
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11 pages, 3790 KiB  
Article
Using Patient-Specific 3D-Printed C1–C2 Interfacet Spacers for the Treatment of Type 1 Basilar Invagination: A Clinical Case Report
by Tim T. Bui, Alexander T. Yahanda, Karan Joseph, Miguel Ruiz-Cardozo, Bernardo A. de Monaco, Alexander Perdomo-Pantoja, Joshua P. Koleske, Sean D. McEvoy and Camilo A. Molina
Biomimetics 2025, 10(6), 408; https://doi.org/10.3390/biomimetics10060408 - 17 Jun 2025
Viewed by 324
Abstract
Background: Type 1 basilar invagination (BI) is caused by a structural instability at the craniovertebral junction (CVJ) and has been historically treated with distraction and stabilization through fusion of the C1–C2 vertebrae. Recent advances in 3D printed custom implants (3DPIs) have improved the [...] Read more.
Background: Type 1 basilar invagination (BI) is caused by a structural instability at the craniovertebral junction (CVJ) and has been historically treated with distraction and stabilization through fusion of the C1–C2 vertebrae. Recent advances in 3D printed custom implants (3DPIs) have improved the array of available options for reaching distraction and alignment goals. Case Presentation: We report the case of a 15-year-old male who presented with early signs of cervical myelopathy. Radiographic evaluation revealed type 1 BI with a widened atlantodental interval (ADI) of 3.7 mm and a 9 mm McRae’s line violation (MLV) of the dens, resulting in severe narrowing at the CVJ and brainstem/spinal cord impingement. Of note, the patient had bilateral dysplastic C1 and C2 anatomy, thus requiring a patient-specific 3DPI to conform to this anatomy and enable sufficient distraction and fusion. Custom 3D printed C1–C2 interfacet spacers were created and implemented within 14 days to achieve sufficient distraction, osteoconduction, and stabilization of the C1–C2 joint. Outcome: Postoperatively, the patient remained neurologically intact with myelopathic symptom improvement before discharge on postoperative day 4. Postoperative imaging demonstrated the resolution of BI from successful C1–C2 joint distraction and confirmed intended implant placement with resolution of canal stenosis. During his 6-week follow-up, the patient remained neurologically stable with intact hardware and preserved alignment. Conclusions: This case is the first in the United States demonstrating the use of custom 3D printed interfacet spacers to achieve successful distraction, decompression, and stabilization of type 1 BI. These patient-specific 3DPIs were designed and created in a streamlined manner and serve as proof-of-concept of pragmatic implant design and manufacturing. Future optimization of the workflow and characterization of long-term patient outcomes should be explored for these types of 3DPI. Full article
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37 pages, 33539 KiB  
Article
Domain-Separated Quantum Neural Network for Truss Structural Analysis with Mechanics-Informed Constraints
by Hyeonju Ha, Sudeok Shon and Seungjae Lee
Biomimetics 2025, 10(6), 407; https://doi.org/10.3390/biomimetics10060407 - 16 Jun 2025
Viewed by 487
Abstract
This study proposes an index-based quantum neural network (QNN) model, built upon a variational quantum circuit (VQC), as a surrogate framework for the static analysis of truss structures. Unlike coordinate-based models, the proposed QNN uses discrete member and node indices as inputs, and [...] Read more.
This study proposes an index-based quantum neural network (QNN) model, built upon a variational quantum circuit (VQC), as a surrogate framework for the static analysis of truss structures. Unlike coordinate-based models, the proposed QNN uses discrete member and node indices as inputs, and it adopts a separate-domain strategy that partitions the structure for parallel training. This architecture reflects the way nature organizes and optimizes complex systems, thereby enhancing both flexibility and scalability. Independent quantum circuits are assigned to each separate domain, and a mechanics-informed loss function based on the force method is formulated within a Lagrangian dual framework to embed physical constraints directly into the training process. As a result, the model achieves high prediction accuracy and fast convergence, even under complex structural conditions with relatively few parameters. Numerical experiments on 2D and 3D truss structures show that the QNN reduces the number of parameters by up to 64% compared to conventional neural networks, while achieving higher accuracy. Even within the same QNN architecture, the separate-domain approach outperforms the single-domain model with a 6.25% reduction in parameters. The proposed index-based QNN model has demonstrated practical applicability for structural analysis and shows strong potential as a quantum-based numerical analysis tool for future applications in building structure optimization and broader engineering domains. Full article
(This article belongs to the Special Issue Nature-Inspired Metaheuristic Optimization Algorithms 2025)
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37 pages, 3765 KiB  
Article
Transition Processes in Technological Systems: Inspiration from Processes in Biological Evolution
by Martin Möller, Olga Speck, Harishankar Thekkepat and Thomas Speck
Biomimetics 2025, 10(6), 406; https://doi.org/10.3390/biomimetics10060406 - 16 Jun 2025
Viewed by 537
Abstract
With environmental challenges intensifying, a fundamental understanding and sustainable management of ongoing transition processes are crucial. Biological evolution provides valuable lessons on how to adapt and thrive under changing conditions. By studying its key principles, we identified analogies between biological evolution and technological [...] Read more.
With environmental challenges intensifying, a fundamental understanding and sustainable management of ongoing transition processes are crucial. Biological evolution provides valuable lessons on how to adapt and thrive under changing conditions. By studying its key principles, we identified analogies between biological evolution and technological transitions in terms of both the Multi-Level Perceptive and the path dependency model. The comparative study also revealed that, despite contrasting time scales, the generation-based and version-based developments are comparable. In addition, interesting similarities were found in the increase and decrease of variety and between fitness and consistency. The lessons learned from biology include “Give it a try”, “Do not close for reconstruction”, and “Keep older versions in the innovation process”. Based on this comparison, we aim to gain insights for a better understanding of how to manage technology transitions and to derive concrete indicators for assessing and monitoring them. In doing so, we can provide action-oriented guidance for developing more sustainable technological solutions for major ongoing transitions, such as the energy transition. Full article
(This article belongs to the Section Biomimetic Design, Constructions and Devices)
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26 pages, 6175 KiB  
Article
Numerical Analysis of Load Reduction in the Gliding Process Achieved by the Bionic Swan’s Webbed-Foot Structures
by Fukui Gao, Xiyan Liu, Xinlin Li, Zhaolin Fan, Houcun Zhou and Wenhua Wu
Biomimetics 2025, 10(6), 405; https://doi.org/10.3390/biomimetics10060405 - 16 Jun 2025
Viewed by 345
Abstract
Webbed-foot gliding water entry is a characteristic water-landing strategy employed by swans and other large waterfowls, demonstrating exceptional low-impact loading and remarkable motion stability. These distinctive biomechanical features offer significant potential for informing the design of cross-medium vehicles’ (CMVs’) water-entry systems. To analyze [...] Read more.
Webbed-foot gliding water entry is a characteristic water-landing strategy employed by swans and other large waterfowls, demonstrating exceptional low-impact loading and remarkable motion stability. These distinctive biomechanical features offer significant potential for informing the design of cross-medium vehicles’ (CMVs’) water-entry systems. To analyze the hydrodynamic mechanisms and flow characteristics during swan webbed-foot gliding entry, the three-dimensional bionic webbed-foot water-entry process was investigated through a computational fluid dynamics (CFD) method coupled with global motion mesh (GMM) technology, with a particular emphasis on elucidating the regulatory effects of entry parameters on dynamic performance. The results demonstrated that the gliding water-entry process can be divided into two distinct phases: stable skipping and surface gliding. During the stable skipping phase, the motion trajectory exhibits quasi-sinusoidal periodic fluctuations, accompanied by multiple water-impact events and significant load variations. In the surface-gliding phase, the kinetic energy of the bionic webbed foot progressively decreases while maintaining relatively stable load characteristics. Increasing the water-entry velocity will enhance impact loads while simultaneously increasing the skipping frequency and distance. Increasing the water-entry angle will primarily intensify the impact load magnitude while slightly reducing the skipping frequency and distance. An optimal pitch angle of 20° provides maximum glide-skip stability for the bio-inspired webbed foot, with angles exceeding 25° or below 15° leading to motion instability. This study on webbed-foot gliding entry behavior provided insights for developing novel bio-inspired entry strategies for cross-medium vehicles, while simultaneously advancing the optimization of impact-mitigation designs in gliding water-entry systems. Full article
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15 pages, 4313 KiB  
Article
Fabrication of EP@PDMS@F-SiO2 Superhydrophobic Composite Coating on Titanium Alloy Substrate
by Chaoming Huang, Jinhe Qi, Jie Li, Xinchi Li, Jiawei Chen, Shuo Fu and Yanning Lu
Biomimetics 2025, 10(6), 404; https://doi.org/10.3390/biomimetics10060404 - 16 Jun 2025
Viewed by 360
Abstract
In this study, a preparation method of superhydrophobic composite coating based on a titanium alloy (Ti-6Al-4V) substrate is proposed. The micro-scale pit array structure was fabricated via laser etching technology. Utilizing the synergistic effects of epoxy resin (EP), polydimethylsiloxane (PDMS), and fluorinated nanosilica [...] Read more.
In this study, a preparation method of superhydrophobic composite coating based on a titanium alloy (Ti-6Al-4V) substrate is proposed. The micro-scale pit array structure was fabricated via laser etching technology. Utilizing the synergistic effects of epoxy resin (EP), polydimethylsiloxane (PDMS), and fluorinated nanosilica (F-SiO2), we successfully prepared an EP@PDMS@F-SiO2 composite coating. The effects of the contents of EP, PDMS, and F-SiO2 on the surface wettability, mechanical stability, and UV durability were studied by optimizing the coating ratio through orthogonal experiments. The results show that the micro–nano composite structure formed by laser etching can effectively fix the coating particles and provide excellent superhydrophobicity on the surface. The coating retains high hydrophobicity after paper abrasion (1000 cm under a 200 g load), demonstrating the mechanical stability of the armor-like structure, High-content F-SiO2 coatings exhibit greater UV durability. In addition, the coating surface has low droplet adhesion and self-cleaning capabilities for efficient contaminant removal. The research provides theoretical and technical support for the design and engineering application of a non-fluorinated, environmentally friendly superhydrophobic coating. Full article
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32 pages, 6847 KiB  
Article
Bionic Energy-Efficient Inverse Kinematics Method Based on Neural Networks for the Legs of Hydraulic Legged Robots
by Jinbo She, Xiang Feng, Bao Xu, Linyang Chen, Yuan Wang, Ning Liu, Wenpeng Zou, Guoliang Ma, Bin Yu and Kaixian Ba
Biomimetics 2025, 10(6), 403; https://doi.org/10.3390/biomimetics10060403 - 14 Jun 2025
Viewed by 313
Abstract
Hydraulic legged robots, with advantages such as high load capacity and power density, have become a strategic driving force in advancing intelligent mobile platform technologies. However, their high energy consumption significantly limits long-duration endurance and efficient operational performance. In this paper, inspired by [...] Read more.
Hydraulic legged robots, with advantages such as high load capacity and power density, have become a strategic driving force in advancing intelligent mobile platform technologies. However, their high energy consumption significantly limits long-duration endurance and efficient operational performance. In this paper, inspired by the excellent autonomous energy-efficient consciousness of mammals endowed by natural evolution, a bionic energy-efficient inverse kinematics method based on neural networks (EIKNN) is proposed for the energy-efficient motion planning of hydraulic legged robots with redundant degrees of freedom (RDOFs). Firstly, the dynamic programming (DP) algorithm is used to solve the optimal joint configuration with minimum energy loss as the goal, and the training data set is generated. Subsequently, the inverse kinematic model of the leg with minimum energy loss is learned based on neural network (NN) simulation of the autonomous energy-efficient consciousness endowed to mammals by natural evolution. Finally, extensive comparative experiments validate the effectiveness and superiority of the proposed method. This method not only significantly reduces energy dissipation in hydraulic legged robots but also lays a crucial foundation for advancing hydraulic legged robot technology toward high efficiency, environmental sustainability, and long-term developmental viability. Full article
(This article belongs to the Special Issue Biomimetic Robot Motion Control)
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16 pages, 2578 KiB  
Article
Multi-Feature Facial Complexion Classification Algorithms Based on CNN
by Xiyuan Cao, Delong Zhang, Chunyang Jin, Zhidong Zhang and Chenyang Xue
Biomimetics 2025, 10(6), 402; https://doi.org/10.3390/biomimetics10060402 - 13 Jun 2025
Viewed by 304
Abstract
Variations in facial complexion serve as a telltale sign of underlying health conditions. Precisely categorizing facial complexions poses a significant challenge due to the subtle distinctions in facial features. Three multi-feature facial complexion classification algorithms leveraging convolutional neural networks (CNNs) are proposed. They [...] Read more.
Variations in facial complexion serve as a telltale sign of underlying health conditions. Precisely categorizing facial complexions poses a significant challenge due to the subtle distinctions in facial features. Three multi-feature facial complexion classification algorithms leveraging convolutional neural networks (CNNs) are proposed. They fuse, splice, or independently train the features extracted from distinct facial regions of interest (ROI), respectively. Innovative frameworks of the three algorithms can more effectively exploit facial features, improving the utilization rate of feature information and classification performance. We trained and validated the three algorithms on the dataset consisting of 721 facial images that we had collected and preprocessed. The comprehensive evaluation reveals that multi-feature fusion and splicing classification algorithms achieve accuracies of 95.98% and 93.76%, respectively. The optimal approach combining multi-feature CNN with machine learning algorithms attains a remarkable accuracy of 97.78%. Additionally, these experiments proved that the multidomain combination was crucial, and the arrangement of ROI features, including the nose, forehead, philtrum, and right and left cheek, was the optimal choice for classification. Furthermore, we employed the EfficientNet model for training on the face image as a whole, which achieves a classification accuracy of 89.37%. The difference in accuracy underscores the superiority and efficacy of multi-feature classification algorithms. The employment of multi-feature fusion algorithms in facial complexion classification holds substantial advantages, ushering in fresh research directions in the field of facial complexion classification and deep learning. Full article
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22 pages, 7090 KiB  
Article
The Structural Design and Optimization of a Novel Independently Driven Bionic Ornithopter
by Mouhui Dai, Ruien Wu, Mingxuan Ye, Kai Gao, Bin Chen, Xinwang Tao and Zhijie Fan
Biomimetics 2025, 10(6), 401; https://doi.org/10.3390/biomimetics10060401 - 13 Jun 2025
Viewed by 304
Abstract
To address the limitations of traditional single-motor bionic ornithopters in terms of environmental adaptability and lift capacity, this study proposes a dual-motor independently driven system utilizing a cross-shaft single-gear crank mechanism to achieve adjustable flap speed and wing frequency, thereby enabling asymmetric flapping [...] Read more.
To address the limitations of traditional single-motor bionic ornithopters in terms of environmental adaptability and lift capacity, this study proposes a dual-motor independently driven system utilizing a cross-shaft single-gear crank mechanism to achieve adjustable flap speed and wing frequency, thereby enabling asymmetric flapping for enhanced environmental adaptability. The design integrates a two-stage reduction gear group to optimize torque transmission and an S1223 high-lift airfoil to improve aerodynamic efficiency. Multiphysics simulations combining computational fluid dynamics (CFD) and finite element analysis (FEA) demonstrate that, under flapping frequencies of 1–3.45 Hz and wind speeds of 1.2–3 m/s, the optimized model achieves 50% and 60% improvements in lift and thrust coefficients, respectively, compared to the baseline. Concurrently, peak stress in critical components (e.g., cam disks and wing rods) is reduced by 37% to 41 MPa, with significantly improved stress uniformity. These results validate the dual-motor system’s capability to dynamically adapt to turbulent airflow through the precise control of wing kinematics, offering innovative solutions for applications such as aerial inspection and precision agriculture. Full article
(This article belongs to the Section Biomimetic Design, Constructions and Devices)
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12 pages, 2399 KiB  
Article
Towards Self-Assembling 3D-Printed Shapes Through Βiomimetic Μechanical Interlocking
by Tino Marte, Savvas Koltsakidis, Thomas Profitiliotis, Emmanouil Tzimtzimis and Dimitrios Tzetzis
Biomimetics 2025, 10(6), 400; https://doi.org/10.3390/biomimetics10060400 - 13 Jun 2025
Viewed by 395
Abstract
While early studies on macroscopic self-assembly peaked in the late 20th century, recent research continues to explore and expand the field’s potential through innovative materials and external control strategies. To harness this potential, a unit cell was designed and 3D-printed that could form [...] Read more.
While early studies on macroscopic self-assembly peaked in the late 20th century, recent research continues to explore and expand the field’s potential through innovative materials and external control strategies. To harness this potential, a unit cell was designed and 3D-printed that could form a face-centered cubic lattice and stabilize it through a biomimetic mechanism for mechanical interlocking. The wing coupling structures of the brown marmorated stink bug were examined under a scanning electron microscope to be used as a source of bio-inspiration for the interlocking mechanism. A total of 20 unit cells were studied in five different self-assembly processes and in different compression scenarios. A maximum average of 34% of unit cells remained stable, and 20% were mechanically interlocked after self-assembly tests. The compression tests performed on a single unit cell revealed that the cell can withstand forces up to 1000 N without any plastic deformation. Pyramid configurations from 5-unit cells were manually assembled and assessed in compression tests. They showed an average compression force of 294 N. As the first study focused on self-assembly through mechanical interlocking, further studies that change the unit cell production and self-assembly processes are expected to improve upon these results. Full article
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17 pages, 1929 KiB  
Article
Bio-Signal-Guided Robot Adaptive Stiffness Learning via Human-Teleoperated Demonstrations
by Wei Xia, Zhiwei Liao, Zongxin Lu and Ligang Yao
Biomimetics 2025, 10(6), 399; https://doi.org/10.3390/biomimetics10060399 - 13 Jun 2025
Viewed by 395
Abstract
Robot learning from human demonstration pioneers an effective mapping paradigm for endowing robots with human-like operational capabilities. This paper proposes a bio-signal-guided robot adaptive stiffness learning framework grounded in the conclusion that muscle activation of the human arm is positively correlated with the [...] Read more.
Robot learning from human demonstration pioneers an effective mapping paradigm for endowing robots with human-like operational capabilities. This paper proposes a bio-signal-guided robot adaptive stiffness learning framework grounded in the conclusion that muscle activation of the human arm is positively correlated with the endpoint stiffness. First, we propose a human-teleoperated demonstration platform enabling real-time modulation of robot end-effector stiffness by human tutors during operational tasks. Second, we develop a dual-stage probabilistic modeling architecture employing the Gaussian mixture model and Gaussian mixture regression to model the temporal–motion correlation and the motion–sEMG relationship, successively. Third, a real-world experiment was conducted to validate the effectiveness of the proposed skill transfer framework, demonstrating that the robot achieves online adaptation of Cartesian impedance characteristics in contact-rich tasks. This paper provides a simple and intuitive way to plan the Cartesian impedance parameters, transcending the classical method that requires complex human arm endpoint stiffness identification before human demonstration or compensation for the difference in human–robot operational effects after human demonstration. Full article
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14 pages, 7961 KiB  
Article
Silanised Fluoride Hydrotalcites as Functional and Multicomponent Fillers for Dental Composites
by Morena Nocchetti, Michela Piccinini, Antonio Scafuri, Alessandro Di Michele and Valeria Ambrogi
Biomimetics 2025, 10(6), 398; https://doi.org/10.3390/biomimetics10060398 - 12 Jun 2025
Viewed by 370
Abstract
Acrylic resin composites with a high filler loading, consisting of a fluoride-containing hydrotalcite incorporated into silica nanoparticles, were prepared. The filler was obtained by a multi-step process. First, ZnAl hydrotalcite in fluoride form (HTlc/F) was functionalised with tetraethoxysilane to form Si-O-M bonds (M [...] Read more.
Acrylic resin composites with a high filler loading, consisting of a fluoride-containing hydrotalcite incorporated into silica nanoparticles, were prepared. The filler was obtained by a multi-step process. First, ZnAl hydrotalcite in fluoride form (HTlc/F) was functionalised with tetraethoxysilane to form Si-O-M bonds (M = Al or Zn) with the brucitic layers. The ethoxysilane groups exposed on the layers were used as nucleation seeds for silica nanoparticles. The composite, named SiO2@HTlc/F, was then functionalised with 3-(trimethoxysilyl)-propyl methacrylate groups and used as a filler for acrylic resins. The methacrylate groups on the surface of the inorganic composite participated in the polymerisation process of the resin by minimising the phase separation between inorganic and polymer through the formation of chemical bonds at the polymer–inorganic interface. The filler in the resin increases the degree of polymerisation, bringing it to values very close to 100%. Finally, preliminary studies on the release of fluoride anions showed that they are released slowly over time. Full article
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65 pages, 2739 KiB  
Systematic Review
Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition
by Evgenia Gkintoni, Stephanos P. Vassilopoulos and Georgios Nikolaou
Biomimetics 2025, 10(6), 397; https://doi.org/10.3390/biomimetics10060397 - 12 Jun 2025
Viewed by 856
Abstract
Background: Multicultural education and second-language acquisition engaged neural networks, supporting executive function, memory, and social cognition in adulthood, represent powerful forms of brain-inspired multisensory learning. The neuroeducational framework integrates neuroscience with pedagogical practice to understand how linguistically and culturally rich environments drive neuroplasticity [...] Read more.
Background: Multicultural education and second-language acquisition engaged neural networks, supporting executive function, memory, and social cognition in adulthood, represent powerful forms of brain-inspired multisensory learning. The neuroeducational framework integrates neuroscience with pedagogical practice to understand how linguistically and culturally rich environments drive neuroplasticity and cognitive adaptation in adult learners. Objective: This systematic review synthesizes findings from 80 studies examining neuroplasticity and cognitive outcomes in adults undergoing multicultural and second-language acquisition, focusing on underlying neural mechanisms and educational effectiveness. Methods: The analysis included randomized controlled trials and longitudinal studies employing diverse neuroimaging techniques (fMRI, MEG, DTI) to assess structural and functional brain network changes. Interventions varied in terms of immersion intensity (ranging from limited classroom contact to complete environmental immersion), multimodal approaches (integrating visual, auditory, and kinesthetic elements), feedback mechanisms (immediate vs. delayed, social vs. automated), and learning contexts (formal instruction, naturalistic acquisition, and technology-enhanced environments). Outcomes encompassed cognitive domains (executive function, working memory, attention) and socio-emotional processes (empathy, cultural adaptation). Results: Strong evidence demonstrates that multicultural and second-language acquisition induce specific neuroplastic adaptations, including enhanced connectivity between language and executive networks, increased cortical thickness in frontal–temporal regions, and white matter reorganization supporting processing efficiency. These neural changes are correlated with significant improvements in working memory, attentional control, and cognitive flexibility. Immersion intensity, multimodal design features, learning context, and individual differences, including age and sociocultural background, moderate the effectiveness of interventions across adult populations. Conclusions: Adult multicultural and second-language acquisition represents a biologically aligned educational approach that leverages natural neuroplastic mechanisms to enhance cognitive resilience. Findings support the design of interventions that engage integrated neural networks through rich, culturally relevant environments, with significant implications for cognitive health across the adult lifespan and for evidence-based educational practice. Full article
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17 pages, 10685 KiB  
Article
Development of a Cuttlefish-Inspired Amphibious Robot with Wave-Motion Propulsion and Rigid–Flexible Coupling
by Yichao Gao, Felix Pancheri, Tim C. Lueth and Yilun Sun
Biomimetics 2025, 10(6), 396; https://doi.org/10.3390/biomimetics10060396 - 12 Jun 2025
Viewed by 364
Abstract
Amphibious robots require efficient locomotion strategies to enable smooth transitions between terrestrial and aquatic environments. Drawing inspiration from the undulatory movements of aquatic organisms such as cuttlefish and knifefish, this study introduces a bio-inspired propulsion system that emulates natural wave-based locomotion to improve [...] Read more.
Amphibious robots require efficient locomotion strategies to enable smooth transitions between terrestrial and aquatic environments. Drawing inspiration from the undulatory movements of aquatic organisms such as cuttlefish and knifefish, this study introduces a bio-inspired propulsion system that emulates natural wave-based locomotion to improve adaptability and propulsion efficiency. A novel mechanism combining crank–rocker and sliding components is proposed to generate wave-like motions in robotic legs and fins, supporting both land crawling and aquatic paddling. By adopting a rigid–flexible coupling design, the system achieves a balance between structural integrity and motion flexibility. The effectiveness of the mechanism is systematically investigated through kinematic modeling, animation-based simulation, and experimental validation. The developed kinematic model captures the principles of wave propagation via the Crank–Slider–Rocker structure, offering insights into motion efficiency and thrust generation. Animation simulations are employed to visually validate the locomotion patterns and assess coordination across the mechanism. A functional prototype is fabricated and tested in both terrestrial and aquatic settings, demonstrating successful amphibious locomotion. The findings confirm the feasibility of the proposed design and underscore its potential in biomimetic robotics and amphibious exploration. Full article
(This article belongs to the Special Issue Bio-Inspired Soft Robotics: Design, Fabrication and Applications)
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14 pages, 3037 KiB  
Article
The Effect of Three-Dimensional Stabilization Thread Design on Biomechanical Fixation and Osseointegration in Type IV Bone
by Nicholas J. Iglesias, Vasudev Vivekanand Nayak, Arthur Castellano, Lukasz Witek, Bruno Martins de Souza, Edmara T. P. Bergamo, Ricky Almada, Blaire V. Slavin, Estevam A. Bonfante and Paulo G. Coelho
Biomimetics 2025, 10(6), 395; https://doi.org/10.3390/biomimetics10060395 - 12 Jun 2025
Viewed by 400
Abstract
Achieving the appropriate primary stability for immediate or early loading in areas with low-density bone, such as the posterior maxilla, is challenging. A three-dimensional (3D) stabilization implant design featuring a tapered body with continuous cutting flutes along the length of the external thread [...] Read more.
Achieving the appropriate primary stability for immediate or early loading in areas with low-density bone, such as the posterior maxilla, is challenging. A three-dimensional (3D) stabilization implant design featuring a tapered body with continuous cutting flutes along the length of the external thread form, with a combination of curved and linear geometric surfaces on the thread’s crest, has the capacity to enhance early biomechanical and osseointegration outcomes compared to implants with traditional buttressed thread profiles. Commercially available implants with a buttress thread design (TP), and an experimental implant that incorporated the 3D stabilization trimmed-thread design (TP 3DS) were used in this study. Six osteotomies were surgically created in the ilium of adult sheep (N = 14). Osteotomy sites were randomized to receive either the TP or TP 3DS implant to reduce site bias. Subjects were allowed to heal for either 3 or 12 weeks (N = 7 sheep/time point), after which samples were collected en bloc (including the implants and surrounding bone) and implants were either subjected to bench-top biomechanical testing (e.g., lateral loading), histological/histomorphometric analysis, or nanoindentation testing. Both implant designs yielded high insertion torque (ITV ≥ 30 N⋅cm) and implant stability quotient (ISQ ≥ 70) values, indicative of high primary stability. Qualitative histomorphological analysis revealed that the TP 3DS group exhibited a continuous bone–implant interface along the threaded region, in contrast to the TP group at the early, 3-week, healing time point. Furthermore, TP 3DS’s cutting flutes along the entire length of the implant permitted the distribution of autologous bone chips within the healing chambers. Histological evaluation at 12 weeks revealed an increase in woven bone containing a greater presence of lacunae within the healing chambers in both groups, consistent with an intramembranous-like healing pattern and absence of bone dieback. The TP 3DS macrogeometry yielded a ~66% increase in average lateral load during pushout testing at baseline (T = 0 weeks, p = 0.036) and significantly higher bone-to-implant contact (BIC) values at 3 weeks post-implantation (p = 0.006), relative to the traditional TP implant. In a low-density (Type IV) bone model, the TP 3DS implant demonstrated improved performance compared to the conventional TP, as evidenced by an increase in baseline lateral loading capacity and increased BIC during the early stages of osseointegration. These findings indicate that the modified implant configuration of the TP 3DS facilitates more favorable biomechanical integration and may promote more rapid and stable bone anchorage under compromised bone quality conditions. Therefore, such improvements could have important clinical implications for the success and longevity of dental implants placed in regions with low bone density. Full article
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36 pages, 1078 KiB  
Review
Radionuclide-Labeled Biomaterials: A Novel Strategy for Tumor-Targeted Therapy
by Shu Zhang, Aiyue Zhang, Xunhao Qi, Zongtai Han, Luqi Song, Jiayu Zhou, Guanglin Wang, Ran Zhu and Jianguo Li
Biomimetics 2025, 10(6), 394; https://doi.org/10.3390/biomimetics10060394 - 11 Jun 2025
Viewed by 542
Abstract
This paper presents a comprehensive review of recent advancements in radionuclide-labeled biomaterials for cancer therapy, with a particular focus on the characteristics, production methods, and labeling techniques of α-particle, β-particle, and Auger electron-based radiotherapy. It explores innovative strategies for targeted delivery systems and [...] Read more.
This paper presents a comprehensive review of recent advancements in radionuclide-labeled biomaterials for cancer therapy, with a particular focus on the characteristics, production methods, and labeling techniques of α-particle, β-particle, and Auger electron-based radiotherapy. It explores innovative strategies for targeted delivery systems and highlights the advantages of theranostics and combination therapies. The application of radionuclide-labeled biomaterials in various cancer types, including prostate cancer, breast cancer, neuroendocrine tumors, gliomas, and melanoma, is systematically summarized. Furthermore, the article critically examines current technological bottlenecks and challenges in clinical translation, while proposing future directions such as AI-assisted dose optimization and multimodal combination therapies. This review provides essential theoretical foundations and practical insights to facilitate the clinical translation of radionuclide-labeled biomaterials. Full article
(This article belongs to the Special Issue Biological Materials and Bioinspired Designs)
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15 pages, 2653 KiB  
Article
Fluid–Structure Interaction Analysis of a Bionic Robotic Fish Based on a Macrofiber Composite Material
by Chenghong Zhang
Biomimetics 2025, 10(6), 393; https://doi.org/10.3390/biomimetics10060393 - 11 Jun 2025
Viewed by 325
Abstract
In this study, the power system of a bionic robotic fish has been significantly simplified, resulting in a reduced volume and enhanced flexibility of both the structure and movement. To comprehensively understand the dynamics, a fluid–structure interaction (FSI) analysis was conducted, considering the [...] Read more.
In this study, the power system of a bionic robotic fish has been significantly simplified, resulting in a reduced volume and enhanced flexibility of both the structure and movement. To comprehensively understand the dynamics, a fluid–structure interaction (FSI) analysis was conducted, considering the intricate interplay between the mollusk’s structure and the surrounding fluid. This analysis took into account the dissipation due to fluid viscosity and the influence of the wake performance around the mollusk. The study examined the relationships between the driving frequency of the input signal and various parameters such as fluid pressure, propulsion force, and propulsion displacement of the soft robot fish head. With the robot fish’s head fixed, the amplitude of propulsion motion and propulsion force were measured. The simulation results closely matched the experimental findings, indicating their potential to predict the propulsion characteristics of the soft robot fish in fluid environments and further improve its performance. Full article
(This article belongs to the Special Issue Bionic Robotic Fish: 2nd Edition)
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18 pages, 5409 KiB  
Article
Research on Motion Transfer Method from Human Arm to Bionic Robot Arm Based on PSO-RF Algorithm
by Yuanyuan Zheng, Hanqi Zhang, Gang Zheng, Yuanjian Hong, Zhonghua Wei and Peng Sun
Biomimetics 2025, 10(6), 392; https://doi.org/10.3390/biomimetics10060392 - 11 Jun 2025
Viewed by 358
Abstract
Although existing motion transfer methods for bionic robot arms are based on kinematic equivalence or simplified dynamic models, they frequently fail to tackle dynamic compliance and real-time adaptability in complex human-like motions. To address this shortcoming, this study presents a motion transfer method [...] Read more.
Although existing motion transfer methods for bionic robot arms are based on kinematic equivalence or simplified dynamic models, they frequently fail to tackle dynamic compliance and real-time adaptability in complex human-like motions. To address this shortcoming, this study presents a motion transfer method from the human arm to a bionic robot arm based on the hybrid PSO-RF (Particle Swarm Optimization-Random Forest) algorithm to improve joint space mapping accuracy and dynamic compliance. Initially, a high-precision optical motion capture (Mocap) system was utilized to record human arm trajectories, and Kalman filtering and a Rauch–Tung–Striebel (RTS) smoother were applied to reduce noise and phase lag. Subsequently, the joint angles of the human arm were computed through geometric vector analysis. Although geometric vector analysis offers an initial estimation of joint angles, its deterministic framework is subject to error accumulation caused by the occlusion of reflective markers and kinematic singularities. To surmount this limitation, this study designed five action sequences for the establishment of the training database for the PSO-RF model to predict joint angles when performing different actions. Ultimately, an experimental platform was built to validate the motion transfer method, and the experimental verification showed that the system attained high prediction accuracy (R2 = 0.932 for the elbow joint angle) and real-time performance with a latency of 0.1097 s. This paper promotes compliant human–robot interaction by dealing with joint-level dynamic transfer challenges, presenting a framework for applications in intelligent manufacturing and rehabilitation robotics. Full article
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22 pages, 6009 KiB  
Article
Teaching Bioinspired Design for Assistive Technologies Using Additive Manufacturing: A Collaborative Experience
by Maria Elizete Kunkel, Alexander Sauer, Carlos Isaacs, Thabata Alcântara Ferreira Ganga, Leonardo Henrique Fazan and Eduardo Keller Rorato
Biomimetics 2025, 10(6), 391; https://doi.org/10.3390/biomimetics10060391 - 11 Jun 2025
Viewed by 383
Abstract
Integrating bioinspired design and additive manufacturing into engineering education fosters innovation to meet the growing demand for accessible, personalized assistive technologies. This paper presents the outcomes of an international course, “3D Prosthetics and Orthotics”, offered to undergraduate students in the Biomimetic program at [...] Read more.
Integrating bioinspired design and additive manufacturing into engineering education fosters innovation to meet the growing demand for accessible, personalized assistive technologies. This paper presents the outcomes of an international course, “3D Prosthetics and Orthotics”, offered to undergraduate students in the Biomimetic program at Westfälische Hochschule (Germany), in collaboration with the 3D Orthotics and Prosthetics Laboratory at the Federal University of São Paulo—UNIFESP (Brazil). The course combined theoretical and hands-on modules covering digital modeling (CAD), simulation (CAE), and fabrication (CAM), enabling students to develop bioinspired assistive devices through a Project-based learning approach. Working in interdisciplinary teams, students addressed real-world rehabilitation challenges by translating biological mechanisms into engineered solutions using additive manufacturing. Resulting prototypes included a hand prosthesis based on the Fin Ray effect, a modular finger prosthesis inspired by tendon–muscle antagonism, and a cervical orthosis designed based on stingray morphology. Each device was digitally modeled, mechanically analyzed, and physically fabricated using open-source and low-cost methods. This initiative illustrates how biomimetic mechanisms and design can be integrated into education to generate functional outcomes and socially impactful health technologies. Grounded in the Mao3D open-source methodology, this experience demonstrates the value of combining nature-inspired principles, digital fabrication, Design Thinking, and international collaboration to advance inclusive, low-cost innovations in assistive technology. Full article
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15 pages, 3484 KiB  
Article
Construction of a Mathematical Model of the Irregular Plantar and Complex Morphology of Mallard Foot and the Bionic Design of a High-Traction Wheel Grouser
by Jinrui Hu, Dianlei Han, Changwei Li, Hairui Liu, Lizhi Ren and Hao Pang
Biomimetics 2025, 10(6), 390; https://doi.org/10.3390/biomimetics10060390 - 11 Jun 2025
Viewed by 329
Abstract
To improve the traction performance of mobile mechanisms on soft ground, such as paddy fields, tidal flats, and swamps, a mallard (Anas platyrhynchos) foot was adopted as a bionic prototype to explore the influence and contribution of the plantar morphology of the toes [...] Read more.
To improve the traction performance of mobile mechanisms on soft ground, such as paddy fields, tidal flats, and swamps, a mallard (Anas platyrhynchos) foot was adopted as a bionic prototype to explore the influence and contribution of the plantar morphology of the toes and webbing on the anti-subsidence function during its locomotion on wet and soft substrates and to apply this to the bionic design of high-traction wheel grousers. A handheld three-dimensional laser scanner was used to scan the main locomotion postures of a mallard foot during ground contact, and the Geomagic Studio software was utilized to repair the scanned model. As a result, the main three-dimensional geometric models of a mallard foot during the process of touching the ground were obtained. The plantar morphology of a mallard foot was divided into three typical parts: the plantar irregular edge curve, the lateral webbing surface, and the medial webbing surface. The main morphological feature curves/surfaces were extracted through computer-aided design software for the fitting and construction of a mathematical model to obtain the fitting equations of the three typical parts, and the mathematical model construction of the plantar irregular morphology of the mallard foot was completed. In order to verify the sand-fixing and flow-limiting characteristics of this morphological feature, based on the discrete element method (DEM), the numerical simulation of the interaction between the plantar surface of the mallard foot and sand particles was carried out. The simulation results show that during the process of the mallard foot penetration into the loose medium, the lateral and medial webbing surfaces cause the particles under the foot to mainly move downward, effectively preventing the particles from spreading around and significantly enhancing the solidification effect of the particles under the sole. Based on the principle and technology of engineering bionics, the plantar morphology and movement attitude characteristics of the mallard were extracted, and the characteristics of concave middle and edge bulge were applied to the wheel grouser design of paddy field wheels. Two types of bionic wheel grousers with different curved surfaces were designed and compared with the traditional wheel grousers of the paddy field wheel. Through pressure-bearing simulation and experiments, the resistance of different wheel grousers during the process of penetrating into sand particles was compared, and the macro–micro behaviors of particle disturbance during the pressure-bearing process were analyzed. The results show that a bionic wheel grouser with unique curved surfaces can well encapsulate sand particles at the bottom of the wheel grouser, and it also has a greater penetration resistance, which plays a crucial role in improving the traction performance of the paddy field wheel and reducing the disturbance to the surrounding sand particles. This paper realizes the transformation from the biological model to the mathematical model of the plantar morphology of the mallard foot and applies it to the bionic design of the wheel grousers of the paddy field wheels, providing a new solution for improving the traction performance of mobile mechanisms on soft ground. Full article
(This article belongs to the Special Issue Bioinspired Engineered Systems)
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24 pages, 4517 KiB  
Article
Bio-Inspired Compliant Joints and Economic MPC Co-Design for Energy-Efficient, High-Speed Locomotion in Snake-like Robots
by Shuai Zhou, Gengbiao Chen, Mingyu Gong, Jing Liu, Peng Xu, Binshuo Liu and Nian Yin
Biomimetics 2025, 10(6), 389; https://doi.org/10.3390/biomimetics10060389 - 11 Jun 2025
Viewed by 348
Abstract
Snake-like robots face critical challenges in energy-efficient locomotion and smooth gait transitions, limiting their real-world deployment. This study introduces a bio-inspired compliant joint design integrated with a hierarchical neural oscillator network and an energy-optimized control framework. The joint mimics biological skeletal flexibility using [...] Read more.
Snake-like robots face critical challenges in energy-efficient locomotion and smooth gait transitions, limiting their real-world deployment. This study introduces a bio-inspired compliant joint design integrated with a hierarchical neural oscillator network and an energy-optimized control framework. The joint mimics biological skeletal flexibility using specialized wheeled mechanisms and adaptive parallel linkages, while the control network enables adaptive gait generation and seamless transitions through a phase-smoothing algorithm. Critically, this work adopts a synergistic design philosophy where mechanical components and control parameters are co-optimized through shared dynamic modeling. The proposed predictive control strategy optimizes locomotion speed while minimizing energy consumption. Experimental simulations demonstrate that the method achieves an 18% higher average forward speed (0.0563 m/s vs. 0.0478 m/s) with 7% lower energy use (0.1952 J vs. 0.2107 J) compared to conventional approaches. Physical prototype testing confirms these improvements under real-world conditions, showing a 12.9% speed increase (0.0531 m/s vs. 0.0470 m/s) and 7.3% energy reduction (0.2147 J vs. 0.2317 J). By unifying mechanical flexibility and adaptive control parameter tuning, this work bridges dynamic performance and energy efficiency, offering a robust solution for unstructured environments. Full article
(This article belongs to the Special Issue Biorobotics: Challenges and Opportunities)
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20 pages, 7815 KiB  
Article
An Enhanced Snow Geese Optimizer Integrating Multiple Strategies for Numerical Optimization
by Baoqi Zhao, Yu Fang and Tianyi Chen
Biomimetics 2025, 10(6), 388; https://doi.org/10.3390/biomimetics10060388 - 11 Jun 2025
Viewed by 316
Abstract
An enhanced snow geese algorithm (ESGA) is proposed to address the problems of the weakened population diversity and unbalanced search tendencies encountered by the snow geese algorithm (SGA) in the search process. First, an adaptive switching strategy is used to dynamically select the [...] Read more.
An enhanced snow geese algorithm (ESGA) is proposed to address the problems of the weakened population diversity and unbalanced search tendencies encountered by the snow geese algorithm (SGA) in the search process. First, an adaptive switching strategy is used to dynamically select the search strategy to balance the exploitation and exploration capabilities. Second, a dominant group guidance strategy is introduced to improve the population quality. Finally, a dominant stochastic difference search strategy is designed to enrich the population diversity and help it escape from the local optimum by co-directing effects in multiple directions. Ablation experiments were performed on the CEC2017 test set to illustrate the improvement mechanism and the degree of compatibility of their improved strategies. The proposed ESGA with a highly cited algorithm and the powerful improved algorithm are compared on the CEC2022 test suite, and the experimental results confirm that the ESGA outperforms the compared algorithms. Finally, the ability of the ESGA to solve complex problems is further highlighted by solving the robot path planning problem. Full article
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14 pages, 731 KiB  
Review
Comparative Analysis of Highly Purified Sericin and Waste-Derived Sericin: Implications for Biomedical Applications
by Federica Paladini, Fabiana D’Urso, Angelica Panico, Carmen Lanzillotti, Francesco Broccolo and Mauro Pollini
Biomimetics 2025, 10(6), 387; https://doi.org/10.3390/biomimetics10060387 - 11 Jun 2025
Viewed by 305
Abstract
Sericin, a natural glycoprotein constituting 20–30% of the silk cocoon, has emerged as a promising biomaterial due to its excellent biological properties, including biocompatibility, antioxidant properties and potential applications in regenerative medicine. The quality and the features of sericin are strongly dependent on [...] Read more.
Sericin, a natural glycoprotein constituting 20–30% of the silk cocoon, has emerged as a promising biomaterial due to its excellent biological properties, including biocompatibility, antioxidant properties and potential applications in regenerative medicine. The quality and the features of sericin are strongly dependent on the extraction and purification methods, which can employ mild conditions to preserve the molecular integrity of the protein or recovery techniques from waste streams produced during the industrial degumming processes. The silk industry prioritizes fiber yield over protein preservation, so often harsh alkaline conditions at high temperatures are adopted. These divergent approaches result in fundamentally different products with distinct molecular characteristics and functional capabilities. This review comprehensively examines the current technological approaches for sericin extraction techniques and for its recovery from textile industry waste, focusing on how these aspects affect the biological properties of the protein and the potential applications. Full article
(This article belongs to the Special Issue Advanced Biomaterials for Wound Healing Application)
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12 pages, 9150 KiB  
Case Report
Guided Bone Regeneration Using a Modified Occlusive Barrier with a Window: A Case Report
by Luis Leiva-Gea, Alfonso Lendínez-Jurado, Paulino Sánchez-Palomino, Bendición Delgado-Ramos, María Daniela Corte-Torres, Isabel Leiva-Gea and Antonio Leiva-Gea
Biomimetics 2025, 10(6), 386; https://doi.org/10.3390/biomimetics10060386 - 10 Jun 2025
Viewed by 355
Abstract
Background: Bone resorption following tooth loss poses significant challenges for dental implant success. Guided bone regeneration (GBR) techniques, particularly in vertically deficient ridges, often require complex procedures and soft tissue management. This case report introduces a modified occlusive barrier with a window, combined [...] Read more.
Background: Bone resorption following tooth loss poses significant challenges for dental implant success. Guided bone regeneration (GBR) techniques, particularly in vertically deficient ridges, often require complex procedures and soft tissue management. This case report introduces a modified occlusive barrier with a window, combined with tricalcium phosphate, to address these challenges. Methods: A 26-year-old female with significant bone loss in the mandibular anterior region underwent GBR using a digitally designed titanium occlusive barrier. The barrier was fabricated using CAD/CAM technology and secured with screws. A blood clot mixed with tricalcium phosphate was used to promote bone regeneration. Postoperative care included regular irrigation, de-epithelialization, and follow-up over six months. Implant placement and histological analysis were performed to evaluate outcomes. Case Presentation: The patient achieved 8.8 mm of vertical and 7.6 mm of horizontal bone regeneration. Histological analysis confirmed the presence of mature, mineralized bone, and keratinized gingiva. The implant was successfully placed, and a fixed prosthesis was restored after four months, with stable results at a three-year follow-up. Conclusion: This technique demonstrates effective bone and soft tissue regeneration in a single procedure, eliminating the need for autologous bone grafts and secondary surgeries. The use of a digitally designed occlusive barrier offers precision, reduces morbidity, and simplifies the surgical process, suggesting a promising advancement in GBR. Further studies are needed to validate these findings. Full article
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23 pages, 6740 KiB  
Article
Numerical Investigations of Flow over Cambered Deflectors at Re = 1 × 105: A Parametric Study
by Gang Wang, Zhi Wang, Zhaoqi Jiao, Pihai Gong and Changtao Guan
Biomimetics 2025, 10(6), 385; https://doi.org/10.3390/biomimetics10060385 - 10 Jun 2025
Viewed by 319
Abstract
The cambered deflectors in aquacultural facilities are applied to enhance hydrodynamic efficiencies or enable flow fields to be fully developed. Given the anticipated improvements with the bio-inspired profiles or tandem configurations, the hydrodynamics of cambered deflectors with the above features are investigated at [...] Read more.
The cambered deflectors in aquacultural facilities are applied to enhance hydrodynamic efficiencies or enable flow fields to be fully developed. Given the anticipated improvements with the bio-inspired profiles or tandem configurations, the hydrodynamics of cambered deflectors with the above features are investigated at Re=1×105. The relationship between force coefficients and local flow behaviors for both bionic and non-bionic isolated deflectors, as well as tandem deflectors, is revealed using kω SST simulation. The dependencies of force coefficients on gap (G), stagger (S), and inclination angles (θ) in tandem deflectors are illustrated using an updated metamodeling workflow with simulated data. It is demonstrated that the variations of force coefficients over angles of attack are related to flow physics in boundary-layer regions. The non-bionic isolated deflector with the θ=10 prevails as the decent performances of CL and γ globally, which is chosen in the following studies. Regarding tandem deflectors, θ plays a more vital role in drag coefficients (CD) and lift coefficients (CL), while the influence of S is not quite considerable compared to G. Aiming for cost minimizations and lift improvements, an optimized tandem case is obtained and justified with the superiorities in flow fields. This study has provided novel insights into the designs and optimizations of cambered deflectors in aquacultural engineering. Full article
(This article belongs to the Special Issue Drag Reduction through Bionic Approaches)
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34 pages, 2554 KiB  
Article
An Improved Whale Optimization Algorithm via Angle Penalized Distance for Automatic Train Operation
by Longda Wang, Yanjie Ju, Long Guo, Gang Liu, Chunlin Li and Yan Chen
Biomimetics 2025, 10(6), 384; https://doi.org/10.3390/biomimetics10060384 - 9 Jun 2025
Viewed by 302
Abstract
This study proposes a novel effective improved whale optimization algorithm via angle penalized distance (IWOA-APD) for automatic train operation (ATO) to effectively improve the ATO quality. Specifically, aiming at the high-quality target speed curve of urban rail trains, a target speed curve multi-objective [...] Read more.
This study proposes a novel effective improved whale optimization algorithm via angle penalized distance (IWOA-APD) for automatic train operation (ATO) to effectively improve the ATO quality. Specifically, aiming at the high-quality target speed curve of urban rail trains, a target speed curve multi-objective optimization model for ATO is established with energy saving, punctuality, accurate stopping, and comfort as the indexes; and the comprehensive evaluation strategy utilizing angle-penalized distance as the evaluation index is proposed to enhance the assessment’s rationality and applicability. On this basis, the IWOA-APD is proposed using strategies of non-linear decreasing convergence factor, solutions of out-of-bounds eliminating via combination of reflection and refraction, mechanisms of genetic evolution with variable probability, and elite maintenance based on fusion distance and crowding degree distance. In addition, the detailed design scheme of IWOA-APD is given. The test results show that the proposed IWOA-APD achieves significant performance improvements compared to traditional MOWOA. In the optimization scenario from Lvshun New Port Station to Tieshan Town Station of Dalian urban rail transit line No.12, the IGD value shows a remarkable 69.1% reduction, while energy consumption decreases by 12.5%. The system achieves a 64.6% improvement in punctuality and a 76.5% enhancement in parking accuracy. Additionally, comfort level improves by 15.9%. Full article
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28 pages, 6802 KiB  
Article
Comprehensive Stiffness Modeling and Evaluation of an Orthopedic Surgical Robot for Enhanced Cutting Operation Performance
by Heqiang Tian, Mengke Zhang, Jiezhong Tan, Zhuo Chen and Guangqing Chen
Biomimetics 2025, 10(6), 383; https://doi.org/10.3390/biomimetics10060383 - 8 Jun 2025
Viewed by 440
Abstract
This study presents an integrated stiffness modeling and evaluation framework for an orthopedic surgical robot, aiming to enhance cutting accuracy and operational stability. A comprehensive stiffness model is developed, incorporating the stiffness of the end-effector, cutting tool, and force sensor. End-effector stiffness is [...] Read more.
This study presents an integrated stiffness modeling and evaluation framework for an orthopedic surgical robot, aiming to enhance cutting accuracy and operational stability. A comprehensive stiffness model is developed, incorporating the stiffness of the end-effector, cutting tool, and force sensor. End-effector stiffness is computed using the virtual joint method based on the Jacobian matrix, enabling accurate analysis of stiffness distribution within the robot’s workspace. Joint stiffness is experimentally identified through laser tracker-based displacement measurements under controlled loads and calculated using a least-squares method. The results show displacement errors below 0.3 mm and joint stiffness estimation errors under 1.5%, with values more consistent and stable than those reported for typical surgical robots. Simulation studies reveal spatial variations in operational stiffness, identifying zones of low stiffness and excessive stiffness. Compared to prior studies where stiffness varied over 50%, the proposed model exhibits superior uniformity. Experimental validation confirms model fidelity, with prediction errors generally below 5%. Cutting experiments on porcine femurs demonstrate real-world applicability, achieving average stiffness prediction errors below 3%, and under 1% in key directions. The model supports stiffness-aware trajectory planning and control, reducing cutting deviation by up to 10% and improving workspace stiffness stability by 30%. This research offers a validated, high-accuracy approach to stiffness modeling for surgical robots, bridging the gap between simulation and clinical application, and providing a foundation for safer, more precise robotic orthopedic procedures. Full article
(This article belongs to the Special Issue Bioinspired Engineered Systems)
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14 pages, 6262 KiB  
Article
Effect of Surfactant on Bubble Formation on Superhydrophobic Surface in Quasi-Static Regime
by Hangjian Ling, John Ready and Daniel O’Coin
Biomimetics 2025, 10(6), 382; https://doi.org/10.3390/biomimetics10060382 - 7 Jun 2025
Viewed by 516
Abstract
We experimentally studied the effect of a surfactant on bubble formation on a superhydrophobic surface (SHS). The bubble was created by injecting gas through an orifice on the SHS at a constant flow rate in the quasi-static regime. The surfactant, 1-pentanol, was mixed [...] Read more.
We experimentally studied the effect of a surfactant on bubble formation on a superhydrophobic surface (SHS). The bubble was created by injecting gas through an orifice on the SHS at a constant flow rate in the quasi-static regime. The surfactant, 1-pentanol, was mixed with water at concentration C ranging from 0 to 0.08 mol/L, corresponding to surface tension σ ranging from 72 to 43 mN/m. We found that as C increased, the bubble detachment volume (Vd) and maximum bubble base radius (Rdmax) decreased. For a low surfactant concentration, the static contact angle θ0 remained nearly constant, and Vd and Rdmax decreased due to lower surface tensions, following the scaling laws Rdmax~σ1/2 and Vd~σ3/2. The bubble shapes at different concentrations were self-similar. The bubble height, bubble base radius, radius at the bubble apex, and neck radius all scaled with the capillary length. For high surfactant concentrations, however, θ0 was greatly reduced, and Vd and Rdmax decreased due to the combined effects of reduced θ0 and smaller σ. Lastly, we found that the surfactant had a negligible impact on the forces acting on the bubble, except for reducing their magnitudes, and had little effect on the dynamics of bubble pinch-off, except for reducing the time and length scales. Overall, our results provide a better understanding of bubble formation on complex surfaces in complex liquids. Full article
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